Gene Overview
| Target Gene: | S100a9 |
| NCBI Official Symbol: | S100a9 |
| Entrez ID: | 20202 |
| Ensembl ID: | ENSMUSG00000056071 |
| Gene Full Name: | S100 calcium binding protein A9 (calgranulin B) |
| Strand: | - |
| Gene Locus: | 3 F1|3 39.91 cM |
| External Links: |
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S100a9 Significantly Regulated by These T(co)Fs
T(co)Fs
that Activate S100a9
T(co)Fs
that Repress S100a9
The Intensity of the Gene Regulated by T(co)Fs:
S100a9-T(co)F Pairs
| Target Gene |
T(co)F | Knock -Method |
Tissue Type | Biosample Name |
Fold Change |
Log2FC | P-value | Corrected _P |
Dataset ID |
|---|---|---|---|---|---|---|---|---|---|
| S100a9 | Arid1a | knockout | Liver | Liver | 2.00109 | 1.00078 | 0.648797517965665 | 0.999999999999956 | DataSet_11_004 |
| S100a9 | Bcl6 | knockout | Bone_marrow | Bone marrow-derived macrophages | 0.237574 | -2.07355 | 0.00119310021470314 | 0.184578692097562 | DataSet_11_014 |
| S100a9 | Cbfb | knockdown | Peripheral_blood | Peripheral CD4+CD25hi cells | 3.93583 | 1.97667 | 0.104785915133021 | 0.904110021500063 | DataSet_11_017 |
| S100a9 | Cbx2 | knockout | Gonads | Embryonic gonads | 1.82476 | 0.867708 | 0.0107997991243629 | 0.0555276731875087 | DataSet_11_018 |
| S100a9 | Cebpa | shRNA | Bone_marrow | Marrow progenitors | 10.0753 | 3.33275 | 0.00686329198749333 | 0.103948936396015 | DataSet_11_019 |
| S100a9 | Cebpe | knockout | Bone_marrow | Bone marrow-derived macrophages | 0.0783969 | -3.67306 | - | - | DataSet_11_023 |
| S100a9 | Dmrt1 | knockout | Testis | Testes | 2.19761 | 1.13594 | 0.264293898507051 | 0.852455438817996 | DataSet_11_024 |
| S100a9 | Dmrt1 | knockout | Ovary | Ovary | 1.88147 | 0.911858 | 0.375207824583362 | 0.667173120110658 | DataSet_11_030 |
| S100a9 | Dmrt1 | knockout | Ovary | Ovary | 1.88147 | 0.911858 | 0.375207824583362 | 0.667173120110658 | DataSet_11_031 |
| S100a9 | E2f4 | knockout | Brain | Forebrain | 0.327599 | -1.61 | - | - | DataSet_11_033 |
| S100a9 | Elf5 | knockout | Mammary_gland | Mammary gland | 4.1038 | 2.03696 | 0.00120300745186293 | 0.174307436967295 | DataSet_11_035 |
| S100a9 | En2 | knockout | Hippocampus | Hippocampus | 1.71277 | 0.776333 | 0.000325765474205524 | 0.0340522819613098 | DataSet_11_037 |
| S100a9 | Gata2 | knockout | Kidney | renal collecting duct cells | 0.202569 | -2.30351 | - | - | DataSet_11_047 |
| S100a9 | Gata4 | knockout | Intestine | Jejunum | 2.83761 | 1.50467 | 0.351741472159232 | 0.79114965530757 | DataSet_11_049 |
| S100a9 | Gfi1 | knockout | Cord_Blood | T-cells | 4.83486 | 2.27347 | 0.312256308996308 | 0.691838556968706 | DataSet_11_053 |
| S100a9 | Irf6 | knockout | Skin | Skin | 76.8083 | 6.26319 | 1.6147507779934e-06 | 0.00197907840649625 | DataSet_11_062 |
| S100a9 | Jarid2 | knockout | Pancreas | Embryonic pancreas | 3.77021 | 1.91465 | 0.0690256047139503 | 0.758178814946143 | DataSet_11_064 |
| S100a9 | Mafg | knockout | Embryo | Whole embryo | 0.489247 | -1.03136 | 0.128975443411609 | 1 | DataSet_11_073 |
| S100a9 | Mbd1 | siRNA | Adipose_tissue | 3T3-L1 cells | 3.71429 | 1.89309 | - | - | DataSet_11_074 |
| S100a9 | Mbd2 | knockout | Lymph | GFP+ BM leukemia cells | 0.303495 | -1.72026 | 0.0121756375321312 | 0.0689846229102993 | DataSet_11_076 |
| S100a9 | Meis1 | knockout | Hematopoietic | KSL hematopoietic cells | 0.499902 | -1.00028 | 0.723470474347848 | 0.995635220774426 | DataSet_11_081 |
| S100a9 | Meis1 | knockout | Bone_marrow | Immortalized myeloid cell | 1.55755 | 0.639275 | 5.47049149661994e-08 | 2.46481992683218e-06 | DataSet_11_082 |
| S100a9 | Myb | shRNA | Hematopoietic | AML cells | 2.92858 | 1.5502 | 5.12712583620711e-05 | 0.0030646027944891 | DataSet_11_084 |
| S100a9 | Neurod1 | knockout | Eye | Pineal gland | 0.531981 | -0.910554 | 0.0812981735011514 | 0.453288300875607 | DataSet_11_087 |
| S100a9 | Neurod1 | knockout | Eye | Pineal gland | 1.8 | 0.847997 | 0.423394518094512 | 0.9983937273602 | DataSet_11_089 |
| S100a9 | Nfil3 | knockout | Bone_marrow | Prepro NK cells | 0.559075 | -0.838888 | 0.00969611683604776 | 0.592103803193821 | DataSet_11_090 |
| S100a9 | Nhlh2 | knockout | Eye | Retina | 0.128677 | -2.95818 | 0.00953244575146336 | 0.523726874680013 | DataSet_11_092 |
| S100a9 | Nr2f2 | knockout | Ovary | E14.5 Ovary | 21.0772 | 4.39761 | 0.216005870117486 | 0.850674961093718 | DataSet_11_094 |
| S100a9 | Otx2 | knockout | Eye | Retina | 2.02778 | 1.0199 | 0.0790777075408179 | 0.999923528647439 | DataSet_11_097 |
| S100a9 | Pax5 | knockout | Bone_marrow | B220+ cells | 0.228331 | -2.1308 | 0.00702895113451477 | 0.104432289026483 | DataSet_11_100 |
| S100a9 | Pbx1 | knockout | Bone_marrow | BM cells | 1.99358 | 0.995361 | 0.25748256886292 | 0.690364281482601 | DataSet_11_102 |
| S100a9 | Pitx2 | knockout | Eye | Cornea | 0.0290232 | -5.10665 | 0.246630577434739 | 0.639894195485409 | DataSet_11_103 |
| S100a9 | Plagl2 | knockout | Intestine | Small intestine | 3.26271 | 1.70607 | 0.446216512223311 | 0.724730538569915 | DataSet_11_104 |
| S100a9 | Pparg | siRNA | Adipose_tissue | Preadipocytes | 3.61371 | 1.85348 | 0.399165602918408 | 0.992522660015251 | DataSet_11_105 |
| S100a9 | Prox1 | knockout | Liver | Liver | 2.65348 | 1.40789 | - | - | DataSet_11_109 |
| S100a9 | Rest | knockout | Brain | Brain | 2.14706 | 1.10236 | 0.267255917478343 | 1 | DataSet_11_113 |
| S100a9 | Runx1 | knockout | Bone_marrow | KSL cells | 0.18292 | -2.45072 | 0.252804760634271 | 0.957554091291132 | DataSet_11_115 |
| S100a9 | Runx1 | knockout | Lymph | ProB cells | 1.5095 | 0.594069 | 0.0745325050272428 | 0.299833626416534 | DataSet_11_116 |
| S100a9 | Runx1 | knockout | Mammary_gland | Luminal epithelial cells | 4.02668 | 2.00959 | 0.413676758031435 | 0.999784944667092 | DataSet_11_117 |
| S100a9 | Sall4 | shRNA | Embryo | ES cells | 2 | 1 | 0.390320638262965 | 0.999840995136314 | DataSet_11_123 |
| S100a9 | Smad1 | knockout | Lung | Lung left lobe | 0.572591 | -0.804423 | 0.0261051117572812 | 0.542998753027287 | DataSet_11_126 |
| S100a9 | Smad4 | siRNA | Brain | bEnd3 | 0.0645009 | -3.95454 | - | - | DataSet_11_127 |
| S100a9 | Smad4 | knockout | Aorta | Aortic arteries | 20.6427 | 4.36756 | 0.00341384326393355 | 0.109190533145224 | DataSet_11_128 |
| S100a9 | Snai1 | knockout | Embryo | Teratoma | 4.06737 | 2.0241 | - | - | DataSet_11_130 |
| S100a9 | Sohlh1 | knockout | Ovary | Ovary | 16.1672 | 4.015 | 3.738491181672e-05 | 0.000813128638683442 | DataSet_11_134 |
| S100a9 | Sohlh2 | knockout | Ovary | Ovary | 3.05852 | 1.61283 | 0.007776137543841 | 0.0363896906623898 | DataSet_11_135 |
| S100a9 | Sox9 | knockout | Lung | Trachea | 8.51469 | 3.08995 | 0.0133975031175023 | 0.15003878645806 | DataSet_11_144 |
| S100a9 | Spdef | knockout | Colon | Colon | 0.24661 | -2.0197 | 0.0480982537263656 | 0.997507742354799 | DataSet_11_146 |
| S100a9 | Spdef | knockout | Stomach | Stomach | 0.301924 | -1.72775 | 0.0708865790367633 | 0.844378361113003 | DataSet_11_147 |
| S100a9 | Stat3 | knockout | Lung | Lung typeII cells | 3.23746 | 1.69486 | 0.0178502637831371 | 0.612118334492788 | DataSet_11_151 |
| S100a9 | Stat4 | knockout | Lymph | Lamina propria lymphocytes | 4.81788 | 2.2684 | 0.000924249988177304 | 0.629991695169029 | DataSet_11_152 |
| S100a9 | Stat6 | knockout | Bone_marrow | Bone marrow-derived macrophages | 5.32048 | 2.41156 | 0.00015449855378085 | 0.00322635552123522 | DataSet_11_153 |
| S100a9 | Tbx1 | knockout | Ear | Otic vesicles | 0.334061 | -1.58182 | 0.518350992443386 | 0.996209135879357 | DataSet_11_154 |
| S100a9 | Tet2 | knockout | Kidney | Kidney | 2.38129 | 1.25174 | 0.429890612329998 | 1 | DataSet_11_159 |
| S100a9 | Tet2 | shRNA | Embryo | ES cells | 0.175158 | -2.51327 | - | - | DataSet_11_161 |
| S100a9 | Tsc22d4 | shRNA | Liver | Liver | 0.439856 | -1.1849 | 0.000312835699270864 | 0.00379567961811132 | DataSet_11_169 |
| S100a9 | Vdr | knockout | Skin | Skin | 1.90067 | 0.926507 | - | - | DataSet_11_177 |
| S100a9 | Wt1 | knockout | Oviduct | Oviduct | 12.0217 | 3.58756 | 0.00390999057449548 | 0.51929206106762 | DataSet_11_180 |
| S100a9 | Xbp1 | siRNA | Liver | Liver | 2.07246 | 1.05135 | 0.168559865114643 | 0.447377954737042 | DataSet_11_181 |
| S100a9 | Yy1 | knockout | Muscle | Skeletal muscle | 0.659481 | -0.600596 | 0.0118131973369328 | 0.03780049125761 | DataSet_11_182 |
| S100a9 | Yy1 | knockout | White_adipose_tissue | Visceral white adipose tissue | 0.607566 | -0.718886 | 0.381406927649704 | 0.581253097294036 | DataSet_11_185 |
| S100a9 | Dnmt1 | siRNA | Pituitary_gland | AtT-20 | 0.537103 | -0.896729 | 5.991676e-02 | 0.9999923 | DataSet_11_187 |
| S100a9 | Cpeb1 | siRNA | Neuron | Neuro-2a | 7.65365 | 2.93615 | - | - | DataSet_11_189 |
| S100a9 | Kdm5b | knockout | Heart | left ventricles | 0.401309 | -1.31721 | 0.3368477305 | 0.9999827 | DataSet_11_210 |
| S100a9 | Dnmt1 | knockout | Embryo | Embryonic fibroblasts | 1.64348 | 0.716752 | 6.232783e-01 | 7.582076e-01 | DataSet_11_192 |
| S100a9 | Dnmt1 | shRNA | Embryo | Embryonic fibroblasts | 0.619512 | -0.690795 | - | - | DataSet_11_196 |
| S100a9 | Tet1 | knockout | Cortex | brain cortex | 1.63984 | 0.713551 | 6.547949e-02 | 0.242058911 | DataSet_11_218 |
| S100a9 | Ezh2 | knockout | Bone_marrow | CD45.2+LSK cells | 3.40282e38 | 256.699 | - | - | DataSet_11_220 |
| S100a9 | Cebpa | shRNA | Bone_marrow | lineage-negative marrow progenitors | 10.0753 | 3.33275 | 5.256839e-03 | 0.103821722 | DataSet_11_199 |
| S100a9 | Dnmt1 | knockout | Liver | Liver | 2.14854 | 1.10336 | 2.431120e-03 | 3.957942e-02 | DataSet_11_232 |
| S100a9 | Bptf | shRNA | Mammary_gland | 4T1 cells | 1.59107 | 0.67 | 1.625341e-01 | 0.610754565 | DataSet_11_223 |
| S100a9 | Smarca4 | shRNA | Embryo | ES cells | 1.74717 | 0.805018 | - | - | DataSet_11_224 |
| S100a9 | Smarca4 | shRNA | Embryo | ES cells | 1.74717 | 0.805018 | - | - | DataSet_11_225 |
| S100a9 | Rag1 | knockout | Bone | Mice fractured callus | 0.57713 | -0.793032 | 7.728263e-03 | 3.459391e-02 | DataSet_11_230 |
| S100a9 | Twist1 | knockout | Bone_marrow | stromal cells | 6.87013 | 2.78034 | - | - | DataSet_11_244 |
| S100a9 | Ezh2 | knockout | Calvaria | calvaria | 0.628205 | -0.670692 | 1.211228e-01 | 0.49841950 | DataSet_11_247 |
| S100a9 | Tet1 | shRNA | Muscle | MLL-ENL-ERtm | 0.580914 | -0.783605 | 1.729637e-02 | 3.894781e-02 | DataSet_11_249 |
| S100a9 | Mecp2 | knockout | Adipose_tissue | brown adipose tissue | 4.09329 | 2.03326 | 5.110643e-05 | 0.039072692 | DataSet_11_253 |
| S100a9 | Mecp2 | knockout | Adipose_tissue | inguinal adipose tissue | 2.44477 | 1.2897 | 6.344125e-02 | 0.2620725 | DataSet_11_254 |
| S100a9 | Eed | knockout | Brain | Forebrain | 0.396326 | -1.33524 | 2.840968e-01 | 7.492072e-01 | DataSet_11_258 |
| S100a9 | Eed | knockout | Brain | hindbrain | 3.12163 | 1.6423 | 9.908052e-03 | 3.922913e-01 | DataSet_11_259 |
| S100a9 | Eed | knockout | Spinal_cord | spinal cord | 0.634279 | -0.65681 | 5.539336e-01 | 9.999790e-01 | DataSet_11_261 |
| S100a9 | Fubp1 | shRNA | Bone_marrow | BM cells | 4.39007 | 2.13424 | 6.348100e-01 | 0.950816799 | DataSet_11_262 |
| S100a9 | Bcl3 | knockout | Bone | Osteoblast | 2.125 | 1.08746 | 7.254617e-01 | 9.038759e-01 | DataSet_11_263 |
| S100a9 | Nsd2 | knockout | Bone_marrow | Bone marrow immature B cells | 1.92739 | 0.94665 | 2.062084e-03 | 0.05522984 | DataSet_11_267 |
| S100a9 | Nr4a1 | knockout | Mammary_gland | PyVT mouse mammary tumor cells | 0.166008 | -2.59068 | 7.709511e-02 | 0.7273107 | DataSet_11_268 |
| S100a9 | Myc | CRISPR | Skeletal_muscle | muscle stem cells | 2.13341 | 1.09316 | 9.130048e-01 | 1.00000000 | DataSet_11_272 |
| S100a9 | Lin28b | knockout | Bone_marrow | Bone marrow immature B cells | 0.376147 | -1.41063 | 7.331072e-01 | 0.9878520 | DataSet_11_274 |
| S100a9 | Pcgf6 | knockout | Liver | Liver | 1.72027 | 0.782636 | 2.762337e-01 | 0.9665401 | DataSet_11_281 |
| S100a9 | Pcgf6 | knockout | Testis | Testis | 0.0430598 | -4.53751 | 3.275802e-01 | 0.8964874 | DataSet_11_282 |
| S100a9 | Dnmt1 | knockout | Cortex | mature Pvergic cortical interneurons | 8.83784 | 3.14369 | 7.955659e-02 | 0.6936949 | DataSet_11_283 |
| S100a9 | Setd2 | knockout | Kidney | primary renal tubular epithelial (RTE) cells | 3.33333 | 1.73697 | - | - | DataSet_11_285 |
| S100a9 | Pdx1 | CRISPR | Liver | Liver | 0.180451 | -2.47032 | 3.781433e-05 | 0.153195007 | DataSet_11_286 |
| S100a9 | Fli1 | CRISPR | Lymph | CD8 T cells | 0.0888889 | -3.49185 | 4.537466e-01 | 0.9999740103 | DataSet_11_288 |
| S100a9 | Med19 | knockout | White_adipose_tissue | Gonadal white adipose tissue | 2.32824 | 1.21924 | 3.972410e-04 | 2.625995e-02 | DataSet_11_289 |
| S100a9 | Irf8 | knockout | Brain | mice brain | 7.59207 | 2.92449 | 6.850108e-03 | 4.172044e-01 | DataSet_11_292 |
| S100a9 | Mkl1 | knockout | Bone_marrow | Bone marrow differentiated macrophages | 0.5 | -1 | 7.377207e-01 | 0.8903623140 | DataSet_11_294 |
| S100a9 | Tfap2a | knockout | Brain | Brain | 0.346154 | -1.53051 | 0.1564792358 | 0.9599640 | DataSet_11_295 |
| S100a9 | Sirt3 | knockout | Pancreatic_islets | pancreatic beta cell | 2.09184 | 1.06477 | 3.154116e-01 | 7.144686e-01 | DataSet_11_297 |
| S100a9 | Phf8 | knockout | prostate | Prostate | 0.161885 | -2.62696 | 0.0646208063 | 0.2881554 | DataSet_11_298 |
| S100a9 | Arid2 | knockout | Muscle | LSK | 1.69889 | 0.764592 | 9.680633e-02 | 9.743848e-01 | DataSet_11_301 |
| S100a9 | Dnmt1 | knockout | Skin | Keratinocytes | 2.73823 | 1.45324 | 8.570023e-03 | 0.1196521149 | DataSet_11_303 |
| S100a9 | Suz12 | knockout | Lung | Alveolar macrophage | 3.92902 | 1.97417 | 2.595629e-01 | 0.6751756060 | DataSet_11_311 |
| S100a9 | Suz12 | knockout | Lung | Alveolar macrophage | 2.94271 | 1.55715 | 2.503980e-03 | 3.494325e-02 | DataSet_11_312 |
| S100a9 | Irf7 | knockout | Bone_marrow | c-kit+ leukemic cells | 0.0393831 | -4.66628 | - | - | DataSet_11_313 |
| S100a9 | Actl6a | knockout | Nerve | sciatic nerve | 2.29576 | 1.19897 | 3.553154e-02 | 0.261675738 | DataSet_11_314 |
| S100a9 | Arid2 | knockout | Bone_marrow | bone marrow leukemia cells | 3.89147 | 1.96031 | 8.945964e-02 | 0.7021662 | DataSet_11_318 |
| S100a9 | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 0.477948 | -1.06508 | 5.436715e-01 | 7.171618e-01 | DataSet_11_320 |
| S100a9 | Prmt1 | siRNA | Adipose_tissue | 3T3-L1 cells | 4 | 2 | 1.945164e-01 | 0.9832045 | DataSet_11_325 |
| S100a9 | Snai1 | knockdown | Heart | Heart | 2.32213 | 1.21545 | 1.327462e-03 | 0.02764805 | DataSet_11_326 |
| S100a9 | Dnmt3l | knockout | Testis | Spermatogonial progenitor cells | 7.20241 | 2.84848 | - | - | DataSet_11_328 |
| S100a9 | Dnmt1 | knockout | Brain | Cortex | 2.11632 | 1.08156 | 2.722318e-02 | 0.2713588565 | DataSet_11_329 |
| S100a9 | Dnmt3a | knockout | Brain | Cortex | 0.343152 | -1.54308 | 1.807149e-01 | 0.7922939 | DataSet_11_330 |
| S100a9 | Ezh2 | shRNA | Brain | SVZ derived neural stem cells | 0.0338884 | -4.88307 | 2.813434e-05 | 3.361216e-03 | DataSet_11_332 |
| S100a9 | Ezh2 | knockout | Eye | Retina | 4.5287 | 2.1791 | 0.4178947949 | 1.0000000 | DataSet_11_334 |
| S100a9 | Dnmt3b | siRNA | Heart | embryonic cardiomyocytes | 11.5 | 3.52356 | 1.826812e-03 | 0.13835186 | DataSet_11_338 |
| S100a9 | Gtf2ird1 | knockout | Lip | Lip | 3.89894 | 1.96308 | 2.844866e-01 | 6.966605e-01 | DataSet_11_339 |
| S100a9 | Dnmt1 | siRNA | Heart | embryonic cardiomyocytes | 0.5 | -1 | 7.183309e-01 | 0.785791405 | DataSet_11_340 |
| S100a9 | Ezh2 | knockout | Small_intestinal_crypts | small intestinal crypts | 0.125 | -3 | 0.2261908536 | 0.3018736 | DataSet_11_341 |
Regulation Region
Expression Atlas of S100a9