Gene Overview
Target Gene: ASCL1
NCBI Official Symbol: ASCL1
Entrez ID: 429
Ensembl ID: ENSG00000139352
Gene Full Name: achaete-scute family bHLH transcription factor 1
Strand: +
Gene Locus: 12q23.2
External Links:

ASCL1 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate ASCL1   
T(co)Fs that Repress ASCL1
The Intensity of the Gene Regulated by T(co)Fs:
ASCL1-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
ASCL1 ESR1 siRNA Mammary_gland MCF7 0.6615 -0.59619 0.00012 0.01382 DataSet_01_111
ASCL1 ID1 siRNA Lung H1650 1.51818 0.60234 0.45828 0.74973 DataSet_01_118
ASCL1 BRD4 shRNA Embryo_kidney HEK293 1.53634 0.6195 - - DataSet_01_119
ASCL1 GATA3 siRNA Mammary_gland MCF7 3.72444 1.89702 1.13059e-09 1.57889e-06 DataSet_01_120
ASCL1 FOXM1 siRNA Central_nervous_system U87 1.71828 0.78097 - - DataSet_01_122
ASCL1 IKZF1 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 1.58838 0.66756 0.33582 0.99993 DataSet_01_138
ASCL1 REST siRNA Adrenal_gland H295R/TR 0.64298 -0.63715 0.00013 0.02168 DataSet_01_145
ASCL1 SF1 siRNA Adrenal_gland H295R/TR 0.65365 -0.61342 0.00011 0.00275 DataSet_01_146
ASCL1 TFAP2C shRNA Mammary_gland MCF7 0.6038 -0.72785 1.0459e-08 1.23352e-07 DataSet_01_150
ASCL1 MYCN siRNA Autonomic_ganglia SKNBE2 0.56973 -0.81165 0.04474 0.26155 DataSet_01_160
ASCL1 HOXB7 siRNA Pancreas MIA PaCa-2 0.6568 -0.60647 0.06593 0.62269 DataSet_01_169
ASCL1 HSF1 shRNA Liver KYN2 0.54037 -0.88797 - - DataSet_01_178
ASCL1 NR5A2 siRNA Mammary_gland MCF7 0.31341 -1.67389 0.00457 0.0532 DataSet_01_182
ASCL1 TCF4 siRNA Autonomic_ganglia SH-SY5Y 0.42864 -1.22215 3.458e-05 0.00683 DataSet_01_185
ASCL1 CREB1 shRNA Parotid_gland H3118 MEC 2.17543 1.1213 0.11065 0.43909 DataSet_01_194
ASCL1 CREB1 shRNA Parotid_gland HSY 0.65053 -0.62031 0.71587 0.98114 DataSet_01_195
ASCL1 TP63 siRNA Head_and_neck SCC-1 2.0782 1.05534 - - DataSet_01_198
ASCL1 HIC1 shRNA Mammary_gland HBL100 0.56646 -0.81996 - - DataSet_01_205
ASCL1 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 1.776 0.82863 - - DataSet_01_209
ASCL1 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 0.38962 -1.35987 - - DataSet_01_210
ASCL1 ERG siRNA Prostate VCaP 3.35171 1.7449 7.29051e-06 0.00082 DataSet_01_216
ASCL1 FOXM1 siRNA Mammary_gland MCF7 3.78887 1.92177 0.13593 0.78354 DataSet_01_223
ASCL1 IRX1 shRNA Bone_marrow 143B 0.59226 -0.7557 0.05383 0.24001 DataSet_01_227
ASCL1 MEF2A shRNA Fetal_spinal_cord SPC04 1.77801 0.83026 0.24792 0.89984 DataSet_01_265
ASCL1 FOXO3 siRNA Pancreas PANC1 0.47801 -1.06488 - - DataSet_01_267
ASCL1 AR shRNA Prostate CWR22Pc 0.4146 -1.27021 0.1465 0.34035 DataSet_01_278
ASCL1 POSTN shRNA Brain GSC272 3.33353 1.73705 0.03508 0.529 DataSet_01_293
ASCL1 TFAP4 siRNA Brain BE(2)-C 0.10075 -3.3112 0.15246 0.51625 DataSet_01_295
ASCL1 PTEN shRNA Lung HCC827 0.53375 -0.90576 0.16709 0.65244 DataSet_01_302
ASCL1 PTEN shRNA Mammary_gland SKBR3 2.27698 1.18712 0.02239 0.49451 DataSet_01_303
ASCL1 SOX9 siRNA Prostate VCaP 1.77524 0.82802 0.09403 0.9316 DataSet_01_308
ASCL1 SOX9 siRNA Prostate VCaP 1.77524 0.82802 0.09403 0.9316 DataSet_01_309
ASCL1 MYC siRNA Colon HCT116 1.77381 0.82685 0.00973 0.02029 DataSet_01_324
ASCL1 HIF1A siRNA Oral_cavity OEC-M1 1.58775 0.66699 0.09137 0.85151 DataSet_01_348
ASCL1 ELK1 siRNA Mammary_gland MDA-MB-231 0.41272 -1.27678 - - DataSet_01_354
ASCL1 GTF2B siRNA Cervix HeLa 0.58817 -0.7657 - - DataSet_01_362
ASCL1 TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 3.28 1.7137 0.00926 0.26063 DataSet_02_129
ASCL1 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.16 -2.64386 0.00031 0.02779 DataSet_02_131
ASCL1 AGO2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.2 -2.32193 0.02828 0.14316 DataSet_02_132
ASCL1 PCBP2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.44 -1.18442 0.0066 0.08749 DataSet_02_135
ASCL1 HNRNPK shRNA Haematopoietic_and_lymphoid_tissue K562 2.16 1.11103 0.00504 0.14579 DataSet_02_136
ASCL1 RBFOX2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.44681 -1.16227 0.22692 0.56652 DataSet_02_139
ASCL1 ILF3 shRNA Haematopoietic_and_lymphoid_tissue K562 0.21277 -2.23266 0.0513 0.31664 DataSet_02_148
ASCL1 RBM39 shRNA Haematopoietic_and_lymphoid_tissue K562 0.63333 -0.65896 0.0759 0.27762 DataSet_02_151
ASCL1 ILF2 shRNA Haematopoietic_and_lymphoid_tissue K562 2.57143 1.36257 0.01875 0.26498 DataSet_02_152
ASCL1 YBX3 shRNA Haematopoietic_and_lymphoid_tissue K562 0.3617 -1.46713 0.21052 0.64256 DataSet_02_153
ASCL1 FUS shRNA Haematopoietic_and_lymphoid_tissue K562 0.29167 -1.77761 0.00214 0.22733 DataSet_02_155
ASCL1 GTF2F1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.56 -0.8365 0.21595 0.99879 DataSet_02_157
ASCL1 TAF15 shRNA Haematopoietic_and_lymphoid_tissue K562 1.76923 0.82312 0.62676 0.77437 DataSet_02_163
ASCL1 SSB shRNA Haematopoietic_and_lymphoid_tissue K562 0.54167 -0.88452 0.20477 0.41494 DataSet_02_164
ASCL1 U2AF1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.3913 -1.35364 0.11412 0.27981 DataSet_02_165
ASCL1 RBM25 shRNA Haematopoietic_and_lymphoid_tissue K562 0.3913 -1.35364 0.11396 0.32203 DataSet_02_166
ASCL1 EWSR1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.64 -0.64386 0.02219 0.22555 DataSet_02_167
ASCL1 RBM22 shRNA Haematopoietic_and_lymphoid_tissue K562 0.24 -2.05889 0.00069 0.05289 DataSet_02_168
ASCL1 TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 7 2.80735 0.00116 0.04354 DataSet_02_169
ASCL1 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.6087 -0.71621 0.37647 0.57175 DataSet_02_171
ASCL1 ZFX siRNA Prostate C4-2B 0.58333 -0.77761 0.78146 0.84939 DataSet_02_172
ASCL1 NFE2L2 siRNA Haematopoietic_and_lymphoid_tissue K562 0.275 -1.8625 0.19629 1 DataSet_02_174
ASCL1 ZNF180 siRNA Haematopoietic_and_lymphoid_tissue K562 0.44828 -1.15754 0.75488 1 DataSet_02_177
ASCL1 VEZF1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.54054 -0.88753 0.24239 1 DataSet_02_179
ASCL1 CTCF siRNA Haematopoietic_and_lymphoid_tissue K562 0.42105 -1.24793 0.18568 1 DataSet_02_185
ASCL1 BHLHE40 siRNA Haematopoietic_and_lymphoid_tissue K562 0.22222 -2.16993 0.18291 1 DataSet_02_186
ASCL1 CHD1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.10586 1 DataSet_02_187
ASCL1 BACH1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.58333 -0.77761 0.3799 1 DataSet_02_188
ASCL1 MAFG siRNA Haematopoietic_and_lymphoid_tissue K562 0.45833 -1.12553 0.96088 1 DataSet_02_189
ASCL1 MAX siRNA Haematopoietic_and_lymphoid_tissue K562 0.5625 -0.83007 0.3173 1 DataSet_02_192
ASCL1 ARID3A siRNA Haematopoietic_and_lymphoid_tissue K562 0.66038 -0.59864 0.5663 1 DataSet_02_193
ASCL1 LMNB1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.60417 -0.72698 0.39101 1 DataSet_02_195
ASCL1 UBTF siRNA Haematopoietic_and_lymphoid_tissue K562 1.91667 0.9386 0.79567 1 DataSet_02_198
ASCL1 BRCA1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.62069 -0.68806 0.21904 1 DataSet_02_202
ASCL1 ZNF384 siRNA Haematopoietic_and_lymphoid_tissue K562 2.6 1.37851 0.04552 1 DataSet_02_203
ASCL1 RCOR1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.70588 0.77052 0.71298 1 DataSet_02_204
ASCL1 E2F6 siRNA Haematopoietic_and_lymphoid_tissue K562 0.52083 -0.94111 0.27873 1 DataSet_02_205
ASCL1 ABL1 siRNA Mammary_gland MCF7 0.475217 -1.07334 0.145442119786354 0.976385569407162 DataSet_03_001
ASCL1 AKT1 siRNA Mammary_gland MCF7 0.415434 -1.26731 0.0950048131408268 0.937512920166337 DataSet_03_002
ASCL1 AR siRNA Prostate CWR22Rv1 1.73007 0.790833 0.000258013013330257 0.0819061127270968 DataSet_03_008
ASCL1 ASCL1 siRNA Lung DMS79 0.5818 -0.781406 0.0666657443145194 0.71296222878669 DataSet_03_016
ASCL1 ATF4 siRNA Skin A375 0.598844 -0.739749 0.134455012599512 0.775512819201899 DataSet_03_018
ASCL1 ATR siRNA Mammary_gland MCF7 0.453388 -1.14118 0.125392729231282 0.999819450785634 DataSet_03_020
ASCL1 BCL6 siRNA Mammary_gland MCF7 0.410043 -1.28615 0.0911367628500065 0.989541443114508 DataSet_03_024
ASCL1 BRCA1 siRNA Mammary_gland MCF7 0.554902 -0.849695 0.234832897177611 0.999850583334387 DataSet_03_028
ASCL1 BRCA2 siRNA Mammary_gland MCF7 0.517089 -0.951517 0.189260500317787 0.999441861952364 DataSet_03_029
ASCL1 CCNA2 siRNA Mammary_gland MCF7 0.477715 -1.06578 0.147858403604672 0.872422373040044 DataSet_03_034
ASCL1 CDK2 siRNA Mammary_gland MCF7 0.589307 -0.762908 0.281039307206055 0.99987175116756 DataSet_03_044
ASCL1 CEBPA siRNA Mammary_gland MCF7 1.58408 0.663641 0.34304412947854 0.999962793175751 DataSet_03_047
ASCL1 CEBPB siRNA Mammary_gland MCF7 0.436199 -1.19694 0.110936223255763 0.993756826434039 DataSet_03_048
ASCL1 CEBPB siRNA Embryo hESC 0.432716 -1.20851 0.0685168612830736 0.410838124135249 DataSet_03_049
ASCL1 CEBPD siRNA Mammary_gland MCF7 0.461497 -1.11561 0.132618940794688 0.999848455332859 DataSet_03_050
ASCL1 CENPF siRNA Mammary_gland MCF7 1.74099 0.79991 0.260462183048842 0.999662524742916 DataSet_03_052
ASCL1 CHEK1 siRNA Mammary_gland MCF7 0.448271 -1.15756 0.120967924370755 0.999587656258211 DataSet_03_053
ASCL1 CREBBP siRNA Mammary_gland MCF7 0.567032 -0.818498 0.250622880046255 0.968255936317567 DataSet_03_055
ASCL1 CTNNB1 siRNA Mammary_gland MCF7 2.31603 1.21165 0.10740180504531 0.999436862066063 DataSet_03_058
ASCL1 E2F1 siRNA Mammary_gland MCF7 2.70057 1.43326 0.0658941558495098 0.999927373439084 DataSet_03_061
ASCL1 E2F5 siRNA Mammary_gland MCF7 2.38193 1.25213 0.0982375856824935 0.999540347732068 DataSet_03_062
ASCL1 ERBB2 siRNA Mammary_gland MCF7 0.517393 -0.950668 0.18960471808182 0.998282799776643 DataSet_03_066
ASCL1 ERF siRNA Mammary_gland MCF7 0.446261 -1.16404 0.119258052334719 0.999855523449227 DataSet_03_067
ASCL1 ESR1 siRNA Mammary_gland MCF7 0.453452 -1.14098 0.050770467629683 0.999753934970283 DataSet_03_068
ASCL1 ESRRA siRNA Mammary_gland MCF7 0.482791 -1.05053 0.152845988087142 0.999964003642835 DataSet_03_072
ASCL1 FOXA1 siRNA Mammary_gland MCF7 0.192022 -2.38066 4.57635996723365e-15 1.95495318007677e-12 DataSet_03_081
ASCL1 FOXA1 siRNA Mammary_gland MCF7 0.192022 -2.38066 4.57635996723365e-15 1.95495318007677e-12 DataSet_03_082
ASCL1 FOXC1 siRNA Mammary_gland MCF7 0.519833 -0.943879 0.192378708742773 0.999669928105298 DataSet_03_084
ASCL1 FOXJ2 siRNA Mammary_gland MCF7 0.522542 -0.936381 0.19548531397535 0.999965704179325 DataSet_03_088
ASCL1 FOXP1 siRNA Mammary_gland MCF7 0.51865 -0.947167 0.191030858516866 0.999975993110711 DataSet_03_099
ASCL1 GATA2 siRNA Lymph Lymphatic endothelial cells 1.82834 0.870531 7.49698110151236e-06 0.000154057605998865 DataSet_03_101
ASCL1 GATA3 siRNA Mammary_gland MCF7 2.05157 1.03673 0.157495624703492 0.999831535534034 DataSet_03_102
ASCL1 GATA6 siRNA Stomach AGS 2.08278 1.05851 0.0653218141935635 0.520006511670522 DataSet_03_108
ASCL1 GATA6 siRNA Stomach KatoIII 0.562501 -0.830072 0.060174918842469 0.568314551268771 DataSet_03_109
ASCL1 GATA6 siRNA Stomach YCC3 0.6009 -0.734804 0.21735603301309 0.812158538195538 DataSet_03_110
ASCL1 HDAC3 siRNA Mammary_gland MCF7 0.55473 -0.850142 0.234613281295913 0.99997791025972 DataSet_03_114
ASCL1 HDAC5 siRNA Mammary_gland MCF7 1.77083 0.824428 0.24755146878704 0.999966625300244 DataSet_03_115
ASCL1 HIC1 CRISPR Prostate PC3 0.412324 -1.27815 - - DataSet_03_118
ASCL1 HIF1A siRNA Mammary_gland MCF7 0.442127 -1.17747 0.115790999806558 0.999966843283762 DataSet_03_119
ASCL1 HOXB7 siRNA Mammary_gland MCF7 0.533875 -0.905427 0.20879845281286 0.999977683706165 DataSet_03_127
ASCL1 HSF2 siRNA Mammary_gland MCF7 1.87466 0.906631 0.208265110594238 0.990969613280381 DataSet_03_130
ASCL1 ID1 siRNA Mammary_gland MCF7 0.468328 -1.09441 0.138908848009683 0.999926480273844 DataSet_03_133
ASCL1 IRF4 siRNA Skin Cutaneous T cell lymphoma HuT-102 cells 0.636605 -0.651529 0.125210255698581 0.998230994452914 DataSet_03_134
ASCL1 JARID1A siRNA Autonomic_ganglia SKNBE2 0.587686 -0.766882 0.00245699798266413 0.191438660714996 DataSet_03_135
ASCL1 JUN siRNA Mammary_gland MCF7 0.456554 -1.13114 0.252365834513504 0.999857657786768 DataSet_03_142
ASCL1 JUND siRNA Mammary_gland MCF7 0.568346 -0.81516 0.128182789469893 0.999848956486105 DataSet_03_145
ASCL1 KDM3A siRNA Mammary_gland MCF7 2.55748 1.35472 2.69723112279421e-06 0.000596681501811466 DataSet_03_146
ASCL1 MAPK1 siRNA Mammary_gland MCF7 0.52073 -0.941392 0.416304492692691 0.999829384224364 DataSet_03_156
ASCL1 MAX siRNA Mammary_gland MCF7 0.394055 -1.34353 0.0803008507030825 0.999907009675999 DataSet_03_158
ASCL1 MCM2 siRNA Mammary_gland MCF7 0.504024 -0.988435 0.17483218414202 0.999925560383539 DataSet_03_161
ASCL1 MEF2D shRNA Liver HuH7 0.294997 -1.76123 - - DataSet_03_162
ASCL1 MEF2D siRNA Liver HuH7 0.614779 -0.701859 - - DataSet_03_163
ASCL1 MYB siRNA Cord_Blood CD34+ progenitor cells 3.2468 1.69902 - - DataSet_03_170
ASCL1 MYBL2 siRNA Mammary_gland MCF7 0.457433 -1.12837 0.128964573883818 0.999907476570542 DataSet_03_176
ASCL1 MYC siRNA Colon HT29 0.496414 -1.01038 - - DataSet_03_177
ASCL1 MYC siRNA Mammary_gland MCF7 0.411932 -1.27952 0.0924792422503077 0.999887767096734 DataSet_03_182
ASCL1 MYCN siRNA Autonomic_ganglia SKNBE2 0.569729 -0.811652 0.0433818747341124 0.268388300179582 DataSet_03_185
ASCL1 NCOR2 siRNA Mammary_gland MCF7 0.387627 -1.36726 0.0762066803573333 0.999834929103349 DataSet_03_193
ASCL1 NMI siRNA Mammary_gland MCF7 0.550125 -0.862169 0.228768108354665 0.783569713919107 DataSet_03_199
ASCL1 PAX3 siRNA Mammary_gland MCF7 0.509522 -0.972782 0.0934694112911043 0.919978041032696 DataSet_03_206
ASCL1 PBX1 siRNA Mammary_gland MCF7 1.5303 0.61381 3.66623680500632e-06 0.00133535922028241 DataSet_03_209
ASCL1 PCNA siRNA Mammary_gland MCF7 2.10656 1.07489 0.144952475309956 0.999448838103647 DataSet_03_210
ASCL1 RB1 siRNA Mammary_gland MCF7 1.60989 0.686961 0.327561689777545 0.999890290262508 DataSet_03_219
ASCL1 RBL2 siRNA Mammary_gland MCF7 0.47475 -1.07476 0.144993790662908 0.999927471951507 DataSet_03_220
ASCL1 RELA siRNA Mammary_gland MCF7 0.461051 -1.117 0.132214626762074 0.999993711976373 DataSet_03_224
ASCL1 SMAD7 siRNA Mammary_gland MCF7 0.43966 -1.18554 0.113754044478349 0.99858912864726 DataSet_03_234
ASCL1 SOX2 siRNA Lung LK2 0.434439 -1.20277 - - DataSet_03_241
ASCL1 SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 3.45902 1.79036 - - DataSet_03_246
ASCL1 SP100 siRNA Mammary_gland MCF7 0.546826 -0.870848 0.224630062660204 0.999952086018951 DataSet_03_252
ASCL1 SSRP1 siRNA Brain BE(2)C cells 0.398734 -1.3265 0.000246203615612842 0.0928253989782013 DataSet_03_255
ASCL1 STAT1 siRNA Mammary_gland MCF7 0.502468 -0.992898 0.17315838934023 0.999890411872485 DataSet_03_256
ASCL1 STAT3 CRISPR Embryo hESC 5.37713 2.42684 0.0410683555890792 0.113548679141437 DataSet_03_258
ASCL1 STAT5B siRNA Mammary_gland MCF7 1.66772 0.737877 0.295724087109381 0.999932708473107 DataSet_03_263
ASCL1 STAT6 siRNA Umbilical_vein HUVEC 0.556463 -0.845643 0.0265115229108369 0.630736138641862 DataSet_03_264
ASCL1 TCEA1 siRNA Mammary_gland MCF7 2.01076 1.00774 0.167697289205425 0.999762252994287 DataSet_03_266
ASCL1 TET3 siRNA Embryo NCCIT 0.579918 -0.78608 0.00132459107304081 0.0158064583855059 DataSet_03_273
ASCL1 TFAP2C siRNA Mammary_gland MCF7 0.64464 -0.633434 0.104632937930207 0.454893850808798 DataSet_03_274
ASCL1 TFE3 siRNA Kidney UOK257-2 3.21362 1.6842 - - DataSet_03_275
ASCL1 TP53 siRNA Mammary_gland MCF7 1.86997 0.903013 0.209869700147263 0.999938217444253 DataSet_03_277
ASCL1 TP53 siRNA Foreskin Neonatal foreskin keratinocytes 0.651579 -0.617987 0.0284437134343427 0.999791649573014 DataSet_03_278
ASCL1 TP53 knockout Haematopoietic_and_lymphoid_tissue MOLP8 1.79409 0.843253 0.0149285520196406 0.553792919172882 DataSet_03_280
ASCL1 WT1 siRNA Mammary_gland MCF7 0.519591 -0.944552 0.192102013369796 0.999957852801679 DataSet_03_285
ASCL1 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 1.55556 0.63743 0.369020225980302 0.77608675388146 DataSet_04_001
ASCL1 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 0.2 -2.32193 0.0567471325495808 0.142352616821918 DataSet_04_002
ASCL1 CHCHD3 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.466667 -1.09954 0.0596537815731039 0.913576075439876 DataSet_04_003
ASCL1 CIZ1 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.35294 1.23447 0.0064190199838623 0.0335292681762142 DataSet_04_004
ASCL1 CTCF CRISPR Haematopoietic_and_lymphoid_tissue K562 1.54839 0.630766 0.130330113904748 0.467893080933659 DataSet_04_005
ASCL1 E4F1 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.64516 0.718229 0.00970273491269495 0.460888933881103 DataSet_04_007
ASCL1 EIF2AK2 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.57895 0.658963 0.0400229704152539 0.480174357057465 DataSet_04_008
ASCL1 ERN1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.645161 -0.632268 0.061079703548619 0.69075240598746 DataSet_04_009
ASCL1 FUBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.36364 1.24101 0.330642290360449 0.457203051156988 DataSet_04_010
ASCL1 FUBP3 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.82353 0.866733 0.0458101864692358 0.748246762324488 DataSet_04_011
ASCL1 MARK2 shRNA Haematopoietic_and_lymphoid_tissue K562 6.75 2.75489 0.000448051959764133 0.0116174763701763 DataSet_04_012
ASCL1 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 311.889 8.28489 0.0322683844255485 0.103238206317235 DataSet_04_014
ASCL1 RPS3 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.51852 0.602664 0.224336314329395 0.625085388906581 DataSet_04_017
ASCL1 XRCC5 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.52941 0.612977 0.00455950494037701 0.157889235774855 DataSet_04_021
ASCL1 YBX1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.148148 -2.75489 0.199597222515738 0.591612722975329 DataSet_04_022
ASCL1 DDX17 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.3 -1.73697 0.0912429279073153 0.618913264720355 DataSet_04_047
ASCL1 RIOK2 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.16667 1.11548 0.645629337773923 0.927222023957068 DataSet_04_076
ASCL1 SEPT11 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.578947 -0.788496 0.489773900588302 1 DataSet_04_077
ASCL1 SNW1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.315789 -1.66297 0.237647425875146 0.392679906851692 DataSet_04_049
ASCL1 HMGA1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.444444 -1.16992 0.464241301776569 0.787684317068168 DataSet_02_75
ASCL1 HMGN3 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.62963 -0.667425 0.690339517426864 0.926792792835266 DataSet_02_45
ASCL1 SNW1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.307692 -1.70044 0.361909031053582 0.753021496036762 DataSet_02_49
ASCL1 TBL1XR1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.55556 0.63743 0.423309351043914 0.612471731989517 DataSet_02_43
ASCL1 TLE2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.51852 0.602665 0.356316327343419 0.527307760481384 DataSet_02_53
ASCL1 CCAR1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.340426 -1.55459 0.233924941393306 0.416352056396427 DataSet_04_064
ASCL1 DDX1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.255319 -1.96963 0.222663242257059 0.660423991964679 DataSet_04_063
ASCL1 HDGF shRNA Haematopoietic_and_lymphoid_tissue K562 2.75 1.45943 0.654159666440401 0.767974556304855 DataSet_04_059
ASCL1 PRPF6 shRNA Haematopoietic_and_lymphoid_tissue K562 0.48 -1.05889 0.421036503329161 0.759372375232137 DataSet_04_065
ASCL1 CNOT3 shRNA Lung A549 0.502795 -0.991957 9.884880e-02 0.8830540 DataSet_03_340
ASCL1 SNAI2 shRNA Pancreas pancreatic cancer stem cells 2.01967 1.01412 1.977621e-01 0.6510154 DataSet_03_306
ASCL1 SNAI2 shRNA Pancreas KLM1 0.398879 -1.32597 4.036228e-03 0.13113020 DataSet_03_307
ASCL1 PBX1 siRNA Mammary_gland MCF7 1.5303 0.61381 4.383171e-06 1.476799e-03 DataSet_03_326
ASCL1 EZH2 shRNA Mammary_gland MCF7 7.75263 2.95468 1.506733e-10 2.622218e-07 DataSet_03_331
ASCL1 EZH2 knockdown Colon HCT116 1.84009 0.879776 0.070934697 0.8488990 DataSet_03_334
ASCL1 EZH2 shRNA Mammary_gland LM2 1.73685 0.796471 7.020077e-01 9.183545e-01 DataSet_03_350
ASCL1 ESR1 siRNA Mammary_gland MCF7 0.132585 -2.91501 4.111392e-04 0.0137129327 DataSet_03_352
ASCL1 PTPN14 CRISPR Brain U5-NPC 0.0328853 -4.92641 2.303159e-04 0.07978596 DataSet_03_357
ASCL1 TP53 CRISPR Brain U5-NPC 2.27291 1.18454 7.807689e-02 2.143312e-01 DataSet_03_358
ASCL1 NCOA3 siRNA Mammary_gland MDA-MB-231 0.417856 -1.25892 8.569087e-01 0.9944303 DataSet_03_361
ASCL1 ARID2 shRNA Haematopoietic_and_lymphoid_tissue MM.1S 3.90692 1.96603 6.551724e-04 2.460772e-03 DataSet_03_362
ASCL1 TP53 knockout Stomach SNU1 0.29117 -1.78006 0.5068641867 0.9454354 DataSet_03_365
ASCL1 DNMT3A knockout Embryo_kidney HEK293T 9.00573 3.17084 - - DataSet_03_369
ASCL1 E2F1 siRNA Nasopharynx HK1 0.6 -0.736966 3.571404e-01 9.722824e-01 DataSet_03_373
ASCL1 ZNF213 siRNA Mammary_gland MCF7 3.63506 1.86198 2.552680e-01 6.592819e-01 DataSet_03_376
ASCL1 EZH2 CRISPR Ovary SKOV3 4 2 2.493245e-01 0.4844524281 DataSet_03_378
ASCL1 NFKB2 siRNA Bone_marrow U2OS 0.333333 -1.58496 6.553791e-02 0.32883079 DataSet_03_381
ASCL1 KAT6A CRISPR Haematopoietic_and_lymphoid_tissue MOLM-13 5.2816 2.40098 0.3589139039 0.8491668 DataSet_03_387
ASCL1 NFKBIA shRNA Bone_marrow U2OS 0.222502 -2.16811 4.884389e-01 0.87005461 DataSet_03_389
ASCL1 YY1 knockdown Liver HepG2 5.25 2.39232 7.405430e-02 1.742776e-01 DataSet_03_390
ASCL1 KDM5A CRISPR Lung GLC16 0.321075 -1.63902 1.122412e-04 0.012004319 DataSet_03_392
ASCL1 IKZF2 CRISPR Lymph CAR T Cell 1.94442 0.959341 3.901850e-01 0.781295552 DataSet_03_397
ASCL1 TLE4 CRISPR Lymph CAR T Cell 4.37723 2.13002 4.684556e-02 0.24629102 DataSet_03_398
ASCL1 SUMO1 CRISPR Bone_marrow U2OS 1.90909 0.932886 1.766666e-02 7.747158e-02 DataSet_03_401
ASCL1 TFAP2A knockout Embryo H9 3.19685 1.67665 5.129766e-03 0.05010921 DataSet_03_405
ASCL1 ZKSCAN3 CRISPR Colon HCT116 2.66667 1.41504 3.588501e-01 0.645639775 DataSet_03_415
ASCL1 BRD4 CRISPR Lymph CD8+ T cells 4 2 - - DataSet_03_420
ASCL1 MAEL CRISPR Liver Alexander cells 0.5 -1 - - DataSet_03_423
ASCL1 FOXP3 CRISPR Peripheral_blood Naive Treg 4.928 2.301 6.011289e-02 0.338625750 DataSet_03_427
ASCL1 CBX2 siRNA Mammary_gland MCF7 8.94142 3.1605 2.337997e-04 0.0022306849 DataSet_03_451
ASCL1 SOX9 knockout Liver HuH7 0.307692 -1.70044 7.786185e-02 1.846301e-01 DataSet_03_463
ASCL1 LIN28A siRNA Mammary_gland MCF7M 0.387528 -1.36763 4.426227e-01 0.7949577 DataSet_03_469
ASCL1 LIN28A siRNA Mammary_gland MCF7M 0.387528 -1.36763 4.426227e-01 0.7949577 DataSet_03_470
ASCL1 EZH2 siRNA Prostate LNCaP 2.33333 1.22239 6.521694e-01 1.0000000 DataSet_03_475
ASCL1 CHCHD3 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.466667 -1.09954 0.2281373 0.8826529 DataSet_04_071
ASCL1 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 1.55556 0.63743 0.64249 0.9239142 DataSet_04_072
ASCL1 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 0.2 -2.32193 0.07372305 0.16560773 DataSet_04_074
Regulation Region
 
T(co)Fs that significantly regulate MCM2 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of ASCL1
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines