Gene Overview
Target Gene: CLIC3
NCBI Official Symbol: CLIC3
Entrez ID: 9022
Ensembl ID: ENSG00000169583
Gene Full Name: chloride intracellular channel 3
Strand: -
Gene Locus: 9q34.3
External Links:

CLIC3 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate CLIC3   
T(co)Fs that Repress CLIC3
The Intensity of the Gene Regulated by T(co)Fs:
CLIC3-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
CLIC3 MYB shRNA Fetal_liver Primary CD34+ hematopoietic stem/progenitor cells (HSPCs) 0.66112 -0.59702 0.00064 0.00222 DataSet_01_102
CLIC3 SPDEF shRNA Mammary_gland MCF7 0.21546 -2.21451 0.23642 0.99999 DataSet_01_107
CLIC3 ARID1A shRNA Ovary OSE4 0.53902 -0.8916 - - DataSet_01_108
CLIC3 ARID1A siRNA Oesophagus OE33 2.10392 1.07308 0.00084 0.04576 DataSet_01_114
CLIC3 ID1 siRNA Lung A549 0.57768 -0.79165 0.17436 0.4108 DataSet_01_117
CLIC3 ZIC2 siRNA Pancreas PANC1 4.81163 2.26652 - - DataSet_01_121
CLIC3 FOXM1 siRNA Central_nervous_system U87 0.34263 -1.54528 - - DataSet_01_122
CLIC3 NFYA shRNA Cervix HeLaS3 2.26386 1.17878 0.00091 0.0172 DataSet_01_131
CLIC3 SOX4 shRNA Parotid_gland ACC3 2.32821 1.21922 0.70594 0.99285 DataSet_01_140
CLIC3 TFAP2C shRNA Mammary_gland MCF7 0.04914 -4.34704 1.14533e-17 3.73397e-15 DataSet_01_150
CLIC3 TEAD4 shRNA Stomach SNU216 0.28636 -1.80408 - - DataSet_01_151
CLIC3 ELK1 siRNA Peripheral_blood CD4+ T cells 2.84932 1.51062 0.00666 0.03925 DataSet_01_162
CLIC3 JUN siRNA Peripheral_blood CD4+ T cells 3.27879 1.71316 0.00111 0.01647 DataSet_01_164
CLIC3 MAF siRNA Peripheral_blood CD4+ T cells 3.12686 1.64471 0.00161 0.03331 DataSet_01_165
CLIC3 NFATC3 siRNA Peripheral_blood CD4+ T cells 2.29136 1.1962 0.01701 0.12444 DataSet_01_166
CLIC3 NFKB1 siRNA Peripheral_blood CD4+ T cells 0.58606 -0.77087 0.2355 0.75634 DataSet_01_167
CLIC3 HOXB7 siRNA Pancreas MIA PaCa-2 0.34125 -1.55112 0.00044 0.33051 DataSet_01_169
CLIC3 ESRRG siRNA Placenta_tissue Trophoblast cells 0.62911 -0.66861 0.03321 0.25964 DataSet_01_173
CLIC3 TP53 siRNA Lung SAECs 4.85802 2.28037 3.98727e-05 0.06154 DataSet_01_175
CLIC3 TP63 shRNA Bladder UC14 4.46791 2.1596 2.12054e-06 0.00011 DataSet_01_183
CLIC3 GATA2 siRNA Prostate LNCaP 2.02395 1.01717 0.10485 0.20246 DataSet_01_193
CLIC3 CREB1 shRNA Parotid_gland H3118 MEC 2.71035 1.43848 0.00188 0.11309 DataSet_01_194
CLIC3 CREB1 shRNA Parotid_gland HSY 2.28105 1.1897 0.13774 0.78551 DataSet_01_195
CLIC3 TP63 siRNA Immortalized_keratinocyte HaCaT RG 2.41679 1.27309 - - DataSet_01_196
CLIC3 TP63 siRNA Head_and_neck SCC-1 2.91842 1.54519 - - DataSet_01_198
CLIC3 TP63 siRNA Immortalized_keratinocyte HaCaT 1.60003 0.6781 - - DataSet_01_200
CLIC3 TP63 siRNA Head_and_neck SCC-012 1.61497 0.69151 - - DataSet_01_201
CLIC3 XBP1 shRNA Mammary_gland T47D 3.87356 1.95366 2.49798e-07 0.00011 DataSet_01_203
CLIC3 XBP1 shRNA Mammary_gland MDA-MB-231 3.0008 1.58535 0.00027 0.00888 DataSet_01_204
CLIC3 HIC1 shRNA Mammary_gland HBL100 0.2742 -1.86671 - - DataSet_01_205
CLIC3 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly10 7.77111 2.95812 - - DataSet_01_208
CLIC3 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 0.4301 -1.21724 - - DataSet_01_209
CLIC3 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 2.36809 1.24373 - - DataSet_01_210
CLIC3 REST siRNA Prostate LNCaP 0.33317 -1.58567 7.36619e-05 0.02212 DataSet_01_211
CLIC3 EGR3 shRNA Prostate M12 2.33053 1.22066 0.00747 0.10382 DataSet_01_212
CLIC3 PTEN shRNA Mammary_gland MCF10A 4.37521 2.12935 2.90466e-09 4.31769e-07 DataSet_01_218
CLIC3 ATM shRNA Mammary_gland MCF10A 0.13909 -2.84588 1.56894e-07 5.63584e-06 DataSet_01_219
CLIC3 KLF9 siRNA Liver HepG2 0.50021 -0.99939 0.01499 0.06453 DataSet_01_222
CLIC3 HIF1A shRNA Liver HuH7 0.34581 -1.53193 - - DataSet_01_224
CLIC3 SNAI2 shRNA Skin Primary human keratinocytes 12.7444 3.67179 0.00014 0.00857 DataSet_01_225
CLIC3 KLF2 shRNA Bone_marrow RPMI8226 2.18411 1.12704 0.08669 0.69185 DataSet_01_226
CLIC3 IRX1 shRNA Bone_marrow 143B 0.16133 -2.63194 0.00779 0.09417 DataSet_01_227
CLIC3 GATA6 siRNA Colon HT29 1.84259 0.88174 - - DataSet_01_247
CLIC3 SOX4 shRNA Mammary_gland MDA-MB-231 2.04688 1.03343 0.00022 0.01417 DataSet_01_260
CLIC3 SIX4 siRNA Ovary PEO1 2.12085 1.08464 0.00173 0.02107 DataSet_01_269
CLIC3 AR shRNA Prostate CWR22Pc 0.49696 -1.0088 0.04722 0.16468 DataSet_01_278
CLIC3 ESRRA shRNA Embryo_kidney 293T 1.77659 0.82911 0.20341 0.7753 DataSet_01_280
CLIC3 MSX1 siRNA Tooth Dental Pulp Cells 2.33227 1.22174 0.04361 0.09713 DataSet_01_281
CLIC3 NFYA shRNA Lung H322 0.56157 -0.83247 4e-04 0.00418 DataSet_01_288
CLIC3 SP3 siRNA Haematopoietic_and_lymphoid_tissue JURKAT 1.8666 0.90041 0.88832 0.98557 DataSet_01_290
CLIC3 SNAI2 siRNA Mammary_gland MCFDCIS 3.83116 1.93778 0.03966 0.53321 DataSet_01_292
CLIC3 POSTN shRNA Brain GSC272 3.74212 1.90385 0.37594 0.69484 DataSet_01_293
CLIC3 TFAP4 siRNA Brain BE(2)-C 0.26128 -1.93634 0.41099 0.51625 DataSet_01_295
CLIC3 MYCN siRNA Brain BE(2)-C 3.82634 1.93596 0.69826 1 DataSet_01_296
CLIC3 SOX7 siRNA Umbilical_vein HUVEC 1.93023 0.94877 0.01759 0.89788 DataSet_01_299
CLIC3 PTEN shRNA Skin A431 0.57929 -0.78764 0.05506 0.19314 DataSet_01_301
CLIC3 PTEN shRNA Lung HCC827 3.78334 1.91966 0.34298 0.74983 DataSet_01_302
CLIC3 ETV5 siRNA Soft_tissue hADSC 0.46103 -1.11707 1.22272e-05 0.00156 DataSet_01_304
CLIC3 SOX9 siRNA Prostate VCaP 1.68817 0.75546 0.20928 0.9316 DataSet_01_308
CLIC3 SOX9 siRNA Prostate VCaP 1.68817 0.75546 0.20928 0.9316 DataSet_01_309
CLIC3 ARNT siRNA Upper_aerodigestive_tract HSC3 3.5395 1.82355 - - DataSet_01_315
CLIC3 ELK3 shRNA Mammary_gland MDA-MB-231 0.14923 -2.74438 6.14748e-07 2.66139e-05 DataSet_01_318
CLIC3 MYC siRNA Colon HCT116 10.0367 3.32721 3.77216e-11 3.71372e-09 DataSet_01_324
CLIC3 GRHL3 siRNA Skin NHEK 0.38836 -1.36455 0.00118 0.1566 DataSet_01_336
CLIC3 KLF4 siRNA Embryo HCE 2.15884 1.11026 0.00179 0.28179 DataSet_01_341
CLIC3 KLF7 siRNA Embryo HCE 1.66911 0.73908 0.03977 0.99985 DataSet_01_342
CLIC3 ARID1A shRNA Uterus iEEC16 0.25972 -1.94497 - - DataSet_01_345
CLIC3 TCF7L1 shRNA Colon HCT116 0.6302 -0.66611 0.00181 0.03113 DataSet_01_346
CLIC3 HIF1A siRNA Oral_cavity OEC-M1 0.66465 -0.58932 0.1723 0.85151 DataSet_01_348
CLIC3 SOX17 siRNA Umbilical_vein HUVEC 1.88654 0.91574 - - DataSet_01_360
CLIC3 AKT1 siRNA Mammary_gland MCF7 0.539576 -0.890102 0.184764459155804 0.937512920166337 DataSet_03_002
CLIC3 AR siRNA Prostate abl cells 1.63699 0.711042 0.853559948660356 0.999852161656754 DataSet_03_004
CLIC3 AR siRNA Prostate LNCaP 0.623482 -0.681581 0.843051724100988 1 DataSet_03_005
CLIC3 ASCL1 siRNA Lung DMS79 0.638183 -0.647957 0.144426945844145 0.809596650115281 DataSet_03_016
CLIC3 ATF4 siRNA Skin A375 2.85453 1.51325 0.0113672787064892 0.775512819201899 DataSet_03_018
CLIC3 ATOH8 siRNA Umbilical_vein HUVEC 0.220647 -2.18019 0.145286537219584 0.885272532352317 DataSet_03_019
CLIC3 ATR siRNA Mammary_gland MCF7 0.640813 -0.642025 0.322735009510051 0.999819450785634 DataSet_03_020
CLIC3 BCL6 siRNA Mammary_gland MCF7 0.372501 -1.42469 0.0520291609597925 0.989541443114508 DataSet_03_024
CLIC3 BCL6 siRNA Lymph Pfeiffer DLBCL 2.55671 1.35429 0.0947059092097923 0.566534934789517 DataSet_03_026
CLIC3 CCNA2 siRNA Mammary_gland MCF7 0.607656 -0.718674 0.27286728608532 0.878655295335484 DataSet_03_034
CLIC3 CDK2 siRNA Mammary_gland MCF7 0.588528 -0.764817 0.246114410747154 0.99987175116756 DataSet_03_044
CLIC3 CEBPA siRNA Mammary_gland MCF7 1.7518 0.808836 0.222750448131122 0.999962793175751 DataSet_03_047
CLIC3 CEBPB siRNA Mammary_gland MCF7 0.427974 -1.2244 0.0837779626428985 0.993756826434039 DataSet_03_048
CLIC3 CEBPD siRNA Mammary_gland MCF7 0.607454 -0.719153 0.272577256482092 0.999848455332859 DataSet_03_050
CLIC3 CHEK1 siRNA Mammary_gland MCF7 0.476968 -1.06804 0.121598170521477 0.999587656258211 DataSet_03_053
CLIC3 CREBBP siRNA Mammary_gland MCF7 0.471468 -1.08477 0.116860088053128 0.963067261754673 DataSet_03_055
CLIC3 CTNNB1 siRNA Mammary_gland MCF7 1.623 0.698663 0.285218630237899 0.999436862066063 DataSet_03_058
CLIC3 E2F1 siRNA Mammary_gland MCF7 2.10281 1.07232 0.120368704060438 0.999927373439084 DataSet_03_061
CLIC3 E2F5 siRNA Mammary_gland MCF7 2.02834 1.0203 0.136161019822491 0.999540347732068 DataSet_03_062
CLIC3 E2F7 siRNA Upper_aerodigestive_tract SCC25 1.79832 0.846649 2.19366955084687e-07 1.28211091992063e-05 DataSet_03_063
CLIC3 ERF siRNA Mammary_gland MCF7 0.464576 -1.10601 0.111101786255144 0.999855523449227 DataSet_03_067
CLIC3 ESR1 siRNA Mammary_gland MCF7 0.599735 -0.737603 0.0682364342026055 0.0941957111169423 DataSet_03_071
CLIC3 FOS siRNA Mammary_gland MCF7 0.408863 -1.29031 0.0715918556120384 0.999966427400474 DataSet_03_079
CLIC3 FOXA1 siRNA Mammary_gland MCF7 3.20824 1.68178 3.5284692172062e-09 1.59695304478902e-06 DataSet_03_080
CLIC3 FOXA1 siRNA Mammary_gland MCF7 2.32612 1.21792 3.70557080028281e-15 1.643848215787e-12 DataSet_03_081
CLIC3 FOXA1 siRNA Mammary_gland MCF7 2.32612 1.21792 3.70557080028281e-15 1.643848215787e-12 DataSet_03_082
CLIC3 FOXC1 siRNA Mammary_gland MCF7 0.472143 -1.08271 0.117434521643819 0.999669928105298 DataSet_03_084
CLIC3 FOXF2 siRNA Mammary_gland MCF10A 1.70377 0.768732 - - DataSet_03_086
CLIC3 FOXJ2 siRNA Mammary_gland MCF7 0.567886 -0.816326 0.218977102739294 0.999965704179325 DataSet_03_088
CLIC3 FOXO1 siRNA Skin primary human dermal lymphatic endothelial cells 0.505386 -0.984544 - - DataSet_03_096
CLIC3 FOXP1 siRNA Mammary_gland MCF7 0.427305 -1.22666 0.0833279352767777 0.999975993110711 DataSet_03_099
CLIC3 GATA6 siRNA Stomach AGS 1.51382 0.598193 0.00208010113651687 0.153212891534941 DataSet_03_108
CLIC3 GRHL3 siRNA Skin Primary neonatal keratinocytes 0.48302 -1.04984 0.000534188604544582 0.10192999448738 DataSet_03_113
CLIC3 HDAC3 siRNA Mammary_gland MCF7 0.556756 -0.844884 0.205107244707581 0.99997791025972 DataSet_03_114
CLIC3 HIC1 CRISPR Prostate PC3 0.453961 -1.13936 - - DataSet_03_118
CLIC3 HIF1A siRNA Mammary_gland MCF7 0.385848 -1.3739 0.0586828206909369 0.999966843283762 DataSet_03_119
CLIC3 HMGA1 siRNA Mammary_gland MDA-MB-231 1.53186 0.615283 0.000899445474555573 0.00557934452921826 DataSet_03_124
CLIC3 HMGA2 siRNA Mammary_gland MDA-MB-231 3.55273 1.82893 0.001641041681597 0.352354322744326 DataSet_03_125
CLIC3 HSF2 siRNA Mammary_gland MCF7 1.79817 0.846526 0.204333851291521 0.990969613280381 DataSet_03_130
CLIC3 IRF4 siRNA Skin Cutaneous T cell lymphoma HuT-102 cells 1.89403 0.921462 0.761045018936787 0.999948959532916 DataSet_03_134
CLIC3 JUN siRNA Mammary_gland MCF7 0.492606 -1.02149 0.0671111707788964 0.999857657786768 DataSet_03_142
CLIC3 JUND siRNA Prostate PC3 1.54285 0.625597 0.00105378980932836 0.236018782283991 DataSet_03_144
CLIC3 JUND siRNA Mammary_gland MCF7 0.401245 -1.31745 0.135776092466645 0.999848956486105 DataSet_03_145
CLIC3 KDM3A siRNA Mammary_gland MCF7 2.09975 1.07022 0.00135372153402622 0.0235773167176233 DataSet_03_146
CLIC3 Klf4 siRNA Skin Primary neonatal keratinocytes 0.619453 -0.690934 0.0564411298770373 0.153778644625974 DataSet_03_147
CLIC3 KLF5 siRNA Colon SW480 0.274948 -1.86277 1.08690943606963e-08 5.36634361323479e-05 DataSet_03_148
CLIC3 KLF5 siRNA Stomach AGS 0.464963 -1.10481 0.000111839079764151 0.0515292611126105 DataSet_03_149
CLIC3 KLF5 siRNA Stomach YCC3 0.244793 -2.03037 0.000426108059745258 0.0386082428191781 DataSet_03_151
CLIC3 MAPK1 siRNA Mammary_gland MCF7 0.478862 -1.06232 0.355609762132226 0.999829384224364 DataSet_03_156
CLIC3 MAPK14 siRNA Mammary_gland MCF7 0.661293 -0.596638 0.123259428142555 0.999824418484635 DataSet_03_157
CLIC3 MAX siRNA Mammary_gland MCF7 0.435442 -1.19945 0.0889184850540934 0.999907009675999 DataSet_03_158
CLIC3 MCM2 siRNA Mammary_gland MCF7 0.4563 -1.13195 0.104448578435011 0.999925560383539 DataSet_03_161
CLIC3 MEF2D shRNA Liver HuH7 0.345455 -1.53343 - - DataSet_03_162
CLIC3 MEF2D siRNA Liver HuH7 1.64577 0.718762 - - DataSet_03_163
CLIC3 MTA2 siRNA Stomach SGC-7901 2.57236 1.36309 - - DataSet_03_169
CLIC3 MYB siRNA Cord_Blood CD34+ progenitor cells 34.8701 5.12392 - - DataSet_03_170
CLIC3 MYB siRNA Prostate DU145 2.10526 1.074 1.1038023475245e-05 0.0055353288158033 DataSet_03_171
CLIC3 MYBL2 siRNA Mammary_gland MCF7 0.606887 -0.720501 0.271762787293124 0.999907476570542 DataSet_03_176
CLIC3 MYC siRNA Colon HT29 6.79739 2.76498 - - DataSet_03_177
CLIC3 NCOR1 siRNA Prostate LNCaP 1.61208 0.688927 0.0212652490713937 0.200478436500231 DataSet_03_192
CLIC3 NCOR2 siRNA Mammary_gland MCF7 0.459885 -1.12065 0.10729614230356 0.999834929103349 DataSet_03_193
CLIC3 NFAT5 siRNA Synovial Primary fibroblast-like synoviocytes 0.283212 -1.82004 0.00298166420163594 0.0883122481343045 DataSet_03_194
CLIC3 NMI siRNA Mammary_gland MCF7 0.448594 -1.15652 0.0985069683604689 0.706928878591624 DataSet_03_199
CLIC3 NR4A3 siRNA Pancreas 1.1B4 0.563791 -0.826769 1.70655466408217e-06 4.34780027720751e-05 DataSet_03_203
CLIC3 PPARG siRNA Peripheral_blood GM-CSF Macrophage 1.54043 0.623333 0.022797127376528 0.793786128876751 DataSet_03_214
CLIC3 RB1 siRNA Mammary_gland MCF7 1.5933 0.672016 0.302392216259298 0.999890290262508 DataSet_03_219
CLIC3 RBL2 siRNA Mammary_gland MCF7 0.314898 -1.66704 0.0295369659236441 0.999927471951507 DataSet_03_220
CLIC3 RELA siRNA Mammary_gland MCF7 0.473777 -1.07772 0.118833598154885 0.999993711976373 DataSet_03_224
CLIC3 SMAD7 siRNA Mammary_gland MCF7 0.56435 -0.825337 0.214512522417075 0.99858912864726 DataSet_03_234
CLIC3 SOX11 siRNA Lung_fibroblast NHLF 2.94324 1.55741 0.100363561284392 0.486761871677231 DataSet_03_237
CLIC3 SOX11 siRNA Lung_fibroblast NHLF 3.65301 1.86909 0.000715216658265038 0.144920899698915 DataSet_03_238
CLIC3 SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 0.233333 -2.09954 - - DataSet_03_246
CLIC3 SOX4 siRNA Mammary_gland MDA-LM2 1.79471 0.843749 0.00102505923271476 0.183183978615408 DataSet_03_247
CLIC3 SP1 siRNA Cervix HeLa 1.64875 0.721374 0.000188545256347519 0.00280807945406157 DataSet_03_249
CLIC3 SP1 siRNA Ovary OVSAYO 1.86552 0.899581 0.00822932375863589 0.123539400856944 DataSet_03_251
CLIC3 STAT1 siRNA Mammary_gland MCF7 0.567233 -0.817986 0.218148031661301 0.999890411872485 DataSet_03_256
CLIC3 STAT3 CRISPR Embryo hESC 0.182541 -2.4537 0.213212395537858 0.28412068552527 DataSet_03_258
CLIC3 STAT5B siRNA Mammary_gland MCF7 1.9318 0.949944 0.160692889316532 0.999932708473107 DataSet_03_263
CLIC3 TFE3 siRNA Kidney UOK257-2 0.321403 -1.63754 - - DataSet_03_275
CLIC3 TP63 siRNA Skin Primary neonatal keratinocytes 0.51629 -0.953748 0.0517407918409717 0.15192499624627 DataSet_03_281
CLIC3 TP63 siRNA Foreskin Neonatal foreskin keratinocytes 1.72779 0.788927 0.101315537198939 0.737723716449684 DataSet_03_282
CLIC3 WT1 siRNA Mammary_gland MCF7 0.54082 -0.886781 0.186193636206562 0.999957852801679 DataSet_03_285
CLIC3 ZNF746 siRNA Colon HCT116 1.93321 0.951 - - DataSet_03_293
CLIC3 ZNF750 siRNA Skin Primary neonatal keratinocytes 0.463874 -1.10819 0.101335688377294 0.297953066097801 DataSet_03_294
CLIC3 PATZ1 siRNA Liver HepG2 0.528728 -0.919403 1.217807e-05 3.189031e-03 DataSet_03_296
CLIC3 PATZ1 siRNA Liver HepG2 0.528728 -0.919403 1.217807e-05 3.189031e-03 DataSet_03_297
CLIC3 EZH2 shRNA Colon SW480 1.68795 0.75527 - - DataSet_03_298
CLIC3 EZH2 knockdown Uterus Ishikawa (ISK) cell 3.02444 1.59667 - - DataSet_03_324
CLIC3 ELF3 CRISPR Bile_duct HBDEC2 0.326728 -1.61384 4.132274e-05 7.104629e-04 DataSet_03_304
CLIC3 ELF3 knockdown Bile_duct HBDEC2 1.64946 0.721996 2.021611e-05 3.944049e-03 DataSet_03_305
CLIC3 SNAI2 shRNA Pancreas pancreatic cancer stem cells 1.54357 0.626267 1.232532e-01 0.6510154 DataSet_03_306
CLIC3 ACTR5 siRNA Muscle RD 1.87332 0.9056 - - DataSet_03_343
CLIC3 EZH2 siRNA Ovary SKOV3 1.68839 0.75565 4.934129e-06 2.298847e-03 DataSet_03_325
CLIC3 EZH2 shRNA Mammary_gland MCF7 3.65155 1.86851 3.011593e-07 7.547293e-05 DataSet_03_331
CLIC3 ARID3B CRISPR Colon HCT15 0.489272 -1.03129 - - DataSet_03_335
CLIC3 TET1 CRISPR Mammary_gland MDA-MB-231 0.188432 -2.40789 9.145665e-04 1.216373e-02 DataSet_03_347
CLIC3 EZH2 shRNA Mammary_gland LM2 0.43786 -1.19146 1.593885e-02 1.960915e-01 DataSet_03_350
CLIC3 SKI CRISPR Blood HL60 4 2 4.984582e-02 0.376639135 DataSet_03_351
CLIC3 ESR1 siRNA Mammary_gland MCF7 0.530077 -0.915727 2.719347e-03 0.0317389570 DataSet_03_352
CLIC3 ETV5 knockdown Colon HT29 0.576998 -0.793362 7.325081e-03 0.099504624 DataSet_03_353
CLIC3 TET1 CRISPR Mammary_gland Hs578T 0.303289 -1.72124 1.930118e-02 7.516495e-02 DataSet_03_355
CLIC3 EP300 shRNA Mammary_gland MCF10AT 0.637037 -0.650551 1.080901e-02 0.077702101 DataSet_03_364
CLIC3 USP22 shRNA Liver PLC_PRF_5 cells 0.548781 -0.865699 3.899092e-01 0.60384428 DataSet_03_368
CLIC3 TPR shRNA Bone_marrow U2OS 2.23936 1.16308 1.938902e-03 5.502673e-02 DataSet_03_370
CLIC3 ZFP36L1 siRNA Urinary_bladder J82 12 3.58496 - - DataSet_03_371
CLIC3 GLI1 siRNA Skeletal_muscle RMS13 0.335407 -1.57602 4.346075e-03 0.046198713 DataSet_03_375
CLIC3 SMARCA2 shRNA Lung NCI-H1944 0.665877 -0.586673 1.709189e-01 5.663216e-01 DataSet_03_377
CLIC3 EZH2 CRISPR Ovary SKOV3 5.56574 2.47657 1.888767e-02 0.1098120014 DataSet_03_378
CLIC3 DDX5 shRNA Stomach HGC-27 2.41451 1.27173 - - DataSet_03_379
CLIC3 NFKB2 siRNA Bone_marrow U2OS 0.333333 -1.58496 2.679121e-02 0.21610549 DataSet_03_381
CLIC3 TCF19 CRISPR Oral_squamous CAL27 2.7574 1.46331 5.564186e-06 0.0020967709 DataSet_03_383
CLIC3 YY1 shRNA Brain GSC1517 0.5 -1 - - DataSet_03_384
CLIC3 NFKBIA shRNA Bone_marrow U2OS 0.170994 -2.54798 1.992068e-01 0.87005461 DataSet_03_389
CLIC3 YY1 knockdown Liver HepG2 0.583333 -0.777608 3.344161e-01 5.021150e-01 DataSet_03_390
CLIC3 ASXL1 CRISPR Embryo iPSC 0.221324 -2.17577 0.2199729597 0.8187866 DataSet_03_394
CLIC3 IKZF2 CRISPR Lymph CAR T Cell 0.5072 -0.979375 7.952020e-04 0.125239846 DataSet_03_397
CLIC3 TLE4 CRISPR Lymph CAR T Cell 0.356727 -1.48711 5.371786e-04 0.06814752 DataSet_03_398
CLIC3 RELA CRISPR Brain T30 2.98724 1.57881 0.0708919789 0.8400824 DataSet_03_399
CLIC3 SUMO1 CRISPR Bone_marrow U2OS 1.89375 0.921246 1.311816e-03 1.641157e-02 DataSet_03_401
CLIC3 JARID2 siRNA Adipose_tissue human adipose tissue derived stem cells 2.52 1.33342 2.244451e-02 0.3239928 DataSet_03_403
CLIC3 TFAP2A knockout Embryo H9 0.101562 -3.29956 4.494487e-04 0.02133083 DataSet_03_405
CLIC3 CHD1 shRNA Prostate LNCaP 0.238095 -2.07039 6.401791e-01 9.413332e-01 DataSet_03_407
CLIC3 MAP3K7 shRNA Prostate LNCaP 0.476191 -1.07039 9.215387e-01 9.629162e-01 DataSet_03_408
CLIC3 STRAP knockout Nerve SK-N-AS 3.00006 1.58499 - - DataSet_03_409
CLIC3 NFATC2 shRNA Haematopoietic_and_lymphoid_tissue THP-1 2.38889 1.25634 4.949464e-01 0.653859225 DataSet_03_418
CLIC3 FOXK2 shRNA Ovary OVCAR-5 0.0605355 -4.04607 2.745826e-03 0.08266460 DataSet_03_419
CLIC3 BRD4 CRISPR Lymph CD8+ T cells 0.32 -1.64386 - - DataSet_03_420
CLIC3 PRDM1 CRISPR Lymph CD8+ T cells 0.04 -4.64386 - - DataSet_03_421
CLIC3 MAEL CRISPR Liver Alexander cells 3.25 1.70044 - - DataSet_03_423
CLIC3 FOXP3 CRISPR Peripheral_blood Naive Treg 0.134658 -2.89263 2.901286e-02 0.252728083 DataSet_03_427
CLIC3 IKZF2 shRNA Lymph Hut78 3.25127 1.701 1.745813e-02 0.40531743 DataSet_03_429
CLIC3 USP7 shRNA Skin xenograft cells 0.4375 -1.19265 0.23746530 0.4348960 DataSet_03_431
CLIC3 POU2AF1 CRISPR Haematopoietic_and_lymphoid_tissue OCI-Ly7 7.508 2.90843 1.111466e-01 0.500930674 DataSet_03_434
CLIC3 EP300 knockout Pancreas HPAF-II orthotopic cells 1.98027 0.985696 2.300768e-02 7.821540e-02 DataSet_03_436
CLIC3 SUFU shRNA Mammary_gland HCC1954 cells 1.76383 0.818714 0.1045216298 0.6455297 DataSet_03_437
CLIC3 SETDB1 shRNA Colon HCT116 2.70367 1.43492 - - DataSet_03_440
CLIC3 DAXX shRNA Mammary_gland MDA-MB-231 0.584639 -0.774383 5.500323e-02 0.25778256 DataSet_03_441
CLIC3 PURA siRNA Cervix HeLa 8 3 6.153620e-03 0.078008436 DataSet_03_444
CLIC3 FOSL1 siRNA Prostate MSKPCa3 1.76471 0.819428 0.2560969941 0.5297688 DataSet_03_445
CLIC3 RELB CRISPR Colon SW480 2.19748 1.13585 1.050528e-01 2.847317e-01 DataSet_03_449
CLIC3 ZFP36L1 CRISPR Lung NCI-H1876 0.294639 -1.76298 2.393231e-01 0.992381486 DataSet_03_454
CLIC3 SMARCA2 shRNA Lung HCC2302 12.8315 3.68161 4.804280e-09 2.332518e-08 DataSet_03_455
CLIC3 PPARG siRNA Aortic_valve Valvular endothelial cell 1.5066 0.591292 4.738407e-03 8.440889e-02 DataSet_03_456
CLIC3 SREBF2 siRNA Umbilical_vein HUVEC 0.467662 -1.09646 1.472418e-01 5.766101e-01 DataSet_03_457
CLIC3 ARID1A shRNA Bile_duct MMNK1 0.052796 -4.24343 1.032225e-04 0.011240404 DataSet_03_458
CLIC3 CREBBP CRISPR Lymph U2932 0.533333 -0.906891 3.742174e-01 1.0000000 DataSet_03_474
Regulation Region
 
T(co)Fs that significantly regulate MCM2 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of CLIC3
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines