Gene Overview
Target Gene: CTHRC1
NCBI Official Symbol: CTHRC1
Entrez ID: 115908
Ensembl ID: ENSG00000164932
Gene Full Name: collagen triple helix repeat containing 1
Strand: +
Gene Locus: 8q22.3
External Links:

CTHRC1 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate CTHRC1   
T(co)Fs that Repress CTHRC1
The Intensity of the Gene Regulated by T(co)Fs:
CTHRC1-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
CTHRC1 HNF1B shRNA Ovary RMG2 0.32896 -1.604 0.00118 0.00481 DataSet_01_103
CTHRC1 HSF1 siRNA Upper_aerodigestive_tract HSC3 0.65969 -0.60014 0.07582 0.27486 DataSet_01_112
CTHRC1 GABPA siRNA Lung A549 1.86109 0.89614 0.00027 0.00108 DataSet_01_113
CTHRC1 ID1 siRNA Lung A549 2.1577 1.10949 0.01539 0.16113 DataSet_01_117
CTHRC1 FOXM1 siRNA Central_nervous_system U87 12.2844 3.61875 - - DataSet_01_122
CTHRC1 IKZF1 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 2.20112 1.13824 0.03677 0.99993 DataSet_01_138
CTHRC1 TFAP2C shRNA Mammary_gland MCF7 1.7431 0.80166 8.497e-08 7.079e-07 DataSet_01_150
CTHRC1 TAL1 shRNA Umbilical_cord_blood ECFCs 0.60274 -0.73039 0.06833 0.55234 DataSet_01_152
CTHRC1 HSF1 shRNA Skin A375 0.33486 -1.57838 0.00011 0.0025 DataSet_01_155
CTHRC1 ELK1 siRNA Peripheral_blood CD4+ T cells 1.89232 0.92016 2e-04 0.00369 DataSet_01_162
CTHRC1 JUN siRNA Peripheral_blood CD4+ T cells 1.69988 0.76544 4e-04 0.00864 DataSet_01_164
CTHRC1 TP53 siRNA Lung SAECs 2.08584 1.06063 0.00019 0.10762 DataSet_01_175
CTHRC1 STAT3 siRNA Oesophagus OE21 1.64984 0.72233 0.00546 0.29992 DataSet_01_180
CTHRC1 STAT3 siRNA Urothelial Scaber 0.61062 -0.71164 1.69013e-06 0.00013 DataSet_01_184
CTHRC1 GABPA shRNA Prostate C4-2B 1854.03 10.8565 0.23895 0.43934 DataSet_01_190
CTHRC1 GABPA shRNA Prostate LNCaP 1123.2 10.1334 0.4634 0.7048 DataSet_01_191
CTHRC1 TP63 siRNA Immortalized_keratinocyte HaCaT RG 5.9898 2.58251 - - DataSet_01_197
CTHRC1 TP63 siRNA Head_and_neck SCC-6 1.80276 0.8502 - - DataSet_01_202
CTHRC1 MITF shRNA Skin COLO829 2.28869 1.19452 0.05145 0.19579 DataSet_01_207
CTHRC1 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 2.29835 1.2006 - - DataSet_01_209
CTHRC1 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 0.25472 -1.97303 - - DataSet_01_210
CTHRC1 EGR3 shRNA Prostate M12 0.52307 -0.93493 0.00634 0.09495 DataSet_01_212
CTHRC1 KLF2 shRNA Bone_marrow RPMI8226 0.45205 -1.14545 0.71419 0.95704 DataSet_01_226
CTHRC1 ESR2 siRNA Mammary_gland BT549 1.50873 0.59333 1.64715e-05 0.00039 DataSet_01_229
CTHRC1 TWIST1 shRNA Stomach CAF32 0.49982 -1.00051 0.0023 0.02597 DataSet_01_253
CTHRC1 TWIST1 shRNA Stomach CAF 0.64306 -0.63698 0.62177 0.88794 DataSet_01_254
CTHRC1 FOXO3 siRNA Pancreas PANC1 1.66004 0.73122 - - DataSet_01_267
CTHRC1 FOXO1 siRNA Umbilical_vein HUVEC 0.47134 -1.08516 8.68061e-05 0.00588 DataSet_01_270
CTHRC1 AR shRNA Prostate CWR22Pc 1.57845 0.65851 0.45633 0.6734 DataSet_01_278
CTHRC1 STAT5 shRNA Prostate CWR22Pc 5.2036 2.37951 0.00395 0.0307 DataSet_01_279
CTHRC1 NFYA shRNA Lung H322 0.63205 -0.6619 0.02602 0.08503 DataSet_01_288
CTHRC1 RELB siRNA Lung A549 1.61599 0.69242 0.00641 0.07112 DataSet_01_294
CTHRC1 TFAP4 siRNA Brain BE(2)-C 0.19636 -2.34839 0.29762 0.51625 DataSet_01_295
CTHRC1 MYCN siRNA Brain BE(2)-C 1.56809 0.64901 0.81511 1 DataSet_01_296
CTHRC1 SOX7 siRNA Umbilical_vein HUVEC 0.64823 -0.62542 0.13992 0.89788 DataSet_01_299
CTHRC1 PTEN shRNA Mammary_gland SKBR3 2.1933 1.1331 0.08073 0.59771 DataSet_01_303
CTHRC1 OVOL2 siRNA Corneal_epithelial Corneal epithelial cells 1.58034 0.66024 0.14398 0.37352 DataSet_01_313
CTHRC1 ARNT siRNA Upper_aerodigestive_tract HSC3 4.84463 2.27639 - - DataSet_01_315
CTHRC1 ZNF25 siRNA Bone_marrow hMSC-TERT4 1.95577 0.96773 0.25207 0.75553 DataSet_01_319
CTHRC1 MYC siRNA Colon HCT116 2.892 1.53207 9.48946e-09 1.92385e-07 DataSet_01_324
CTHRC1 NFE2L2 siRNA Lung A549 1.79963 0.8477 3.35094e-07 3.37703e-05 DataSet_01_335
CTHRC1 HIF1A siRNA Oral_cavity OEC-M1 0.48376 -1.04764 0.15988 0.85151 DataSet_01_348
CTHRC1 SOX2 shRNA Neuroepithelium HF2303 0.60449 -0.72621 0.12569 1 DataSet_01_349
CTHRC1 PAX3 shRNA Soft_tissue Rh30 0.65081 -0.6197 - - DataSet_01_359
CTHRC1 GTF2B siRNA Cervix HeLa 1.56513 0.64628 - - DataSet_01_362
CTHRC1 RBM17 shRNA Liver HepG2 0.62274 -0.6833 0.03103 0.27426 DataSet_02_100
CTHRC1 RBFOX2 shRNA Liver HepG2 1.87837 0.90948 0.01896 0.65168 DataSet_02_101
CTHRC1 FIP1L1 shRNA Liver HepG2 6.79387 2.76423 4.99373e-05 0.0094 DataSet_02_103
CTHRC1 HDGF shRNA Liver HepG2 1.66572 0.73615 0.00841 0.08745 DataSet_02_104
CTHRC1 SSB shRNA Liver HepG2 0.07732 -3.69296 1.48919e-05 0.00314 DataSet_02_107
CTHRC1 BCLAF1 shRNA Liver HepG2 0.64975 -0.62204 0.01354 0.05706 DataSet_02_112
CTHRC1 XRCC5 shRNA Liver HepG2 2.42254 1.27652 0.00079 0.12055 DataSet_02_114
CTHRC1 PCBP1 shRNA Liver HepG2 4.39387 2.13549 9.98203e-05 0.01339 DataSet_02_115
CTHRC1 SUB1 shRNA Liver HepG2 1.62188 0.69767 0.01974 0.156 DataSet_02_117
CTHRC1 PTBP1 shRNA Liver HepG2 5.28736 2.40255 4.82722e-05 0.00582 DataSet_02_120
CTHRC1 FUS shRNA Liver HepG2 2.11601 1.08134 0.00096 0.05046 DataSet_02_124
CTHRC1 HNRNPLL shRNA Liver HepG2 0.39445 -1.34207 0.01463 0.04177 DataSet_02_125
CTHRC1 SNRNP70 shRNA Liver HepG2 2.42921 1.28048 0.07397 0.15617 DataSet_02_126
CTHRC1 PRPF4 shRNA Liver HepG2 0.14977 -2.73914 3e-04 0.02426 DataSet_02_128
CTHRC1 TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 0.29245 -1.77372 0.2276 0.51706 DataSet_02_129
CTHRC1 POLR2G shRNA Haematopoietic_and_lymphoid_tissue K562 3.28571 1.71621 0.53692 0.85748 DataSet_02_130
CTHRC1 AGO2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.30097 -1.7323 0.0656 0.20065 DataSet_02_132
CTHRC1 SRSF7 shRNA Haematopoietic_and_lymphoid_tissue K562 0.37736 -1.40599 0.03789 0.26288 DataSet_02_133
CTHRC1 PCBP2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.06604 -3.92057 0.00285 0.08267 DataSet_02_135
CTHRC1 HNRNPK shRNA Haematopoietic_and_lymphoid_tissue K562 0.29245 -1.77372 0.09684 0.28856 DataSet_02_136
CTHRC1 RBM17 shRNA Haematopoietic_and_lymphoid_tissue K562 0.57647 -0.79468 0.1461 0.42106 DataSet_02_138
CTHRC1 TAF15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.4955 -1.01306 0.11149 0.32963 DataSet_02_140
CTHRC1 BCLAF1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.47126 -1.08539 0.05987 0.19516 DataSet_02_142
CTHRC1 FIP1L1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.48077 -1.05658 0.27206 0.41975 DataSet_02_147
CTHRC1 ILF3 shRNA Haematopoietic_and_lymphoid_tissue K562 0.39326 -1.34645 0.0489 0.31324 DataSet_02_148
CTHRC1 NONO shRNA Haematopoietic_and_lymphoid_tissue K562 0.34821 -1.52195 0.00441 0.19424 DataSet_02_149
CTHRC1 RBM39 shRNA Haematopoietic_and_lymphoid_tissue K562 0.31959 -1.64572 0.18244 0.38447 DataSet_02_151
CTHRC1 ILF2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.25352 -1.97982 0.3793 0.67042 DataSet_02_152
CTHRC1 SRSF4 shRNA Haematopoietic_and_lymphoid_tissue K562 0.60656 -0.72128 0.47674 0.71366 DataSet_02_154
CTHRC1 GTF2F1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.5082 -0.97654 0.2934 0.99879 DataSet_02_157
CTHRC1 XRCC5 shRNA Haematopoietic_and_lymphoid_tissue K562 0.36066 -1.47131 0.14752 0.71227 DataSet_02_159
CTHRC1 HNRNPL shRNA Haematopoietic_and_lymphoid_tissue K562 1.78261 0.83399 0.06878 0.2187 DataSet_02_160
CTHRC1 AGO1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.57895 -0.7885 0.15792 0.63184 DataSet_02_162
CTHRC1 TAF15 shRNA Haematopoietic_and_lymphoid_tissue K562 2.90476 1.53842 0.19511 0.43556 DataSet_02_163
CTHRC1 SSB shRNA Haematopoietic_and_lymphoid_tissue K562 1.76316 0.81816 0.10672 0.30508 DataSet_02_164
CTHRC1 U2AF1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.46847 -1.09398 0.11001 0.27465 DataSet_02_165
CTHRC1 RBM25 shRNA Haematopoietic_and_lymphoid_tissue K562 0.35135 -1.50901 0.03313 0.21146 DataSet_02_166
CTHRC1 EWSR1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.59804 -0.74169 0.14252 0.36231 DataSet_02_167
CTHRC1 ZFX siRNA Prostate C4-2B 1.51515 0.59946 0.56723 0.67234 DataSet_02_172
CTHRC1 LMNA siRNA Haematopoietic_and_lymphoid_tissue K562 0.52 -0.94342 0.2796 1 DataSet_02_175
CTHRC1 ZNF180 siRNA Haematopoietic_and_lymphoid_tissue K562 0.46269 -1.11189 0.96305 1 DataSet_02_177
CTHRC1 TBL1XR1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.37931 -1.39855 0.37852 1 DataSet_02_178
CTHRC1 VEZF1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.53143 -0.91205 0.83788 1 DataSet_02_179
CTHRC1 ZMIZ1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.80769 0.85415 0.17574 1 DataSet_02_181
CTHRC1 STAT5A siRNA Haematopoietic_and_lymphoid_tissue K562 0.34043 -1.55459 0.46663 1 DataSet_02_182
CTHRC1 CTCF siRNA Haematopoietic_and_lymphoid_tissue K562 2.97778 1.57424 0.21007 1 DataSet_02_185
CTHRC1 BHLHE40 siRNA Haematopoietic_and_lymphoid_tissue K562 1.6 0.67807 0.45103 1 DataSet_02_186
CTHRC1 CHD1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.58182 0.66158 0.1989 1 DataSet_02_187
CTHRC1 LMNB2 siRNA Haematopoietic_and_lymphoid_tissue K562 0.34286 -1.54432 0.12281 1 DataSet_02_191
CTHRC1 ARID3A siRNA Haematopoietic_and_lymphoid_tissue K562 0.34545 -1.53343 0.05783 1 DataSet_02_193
CTHRC1 TCP1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.36 -1.47393 0.10013 1 DataSet_02_194
CTHRC1 LMNB1 siRNA Haematopoietic_and_lymphoid_tissue K562 4.14583 2.05166 0.98766 1 DataSet_02_195
CTHRC1 CHD2 siRNA Haematopoietic_and_lymphoid_tissue K562 0.59375 -0.75207 0.65858 0.74419 DataSet_02_196
CTHRC1 UBTF siRNA Haematopoietic_and_lymphoid_tissue K562 4.26923 2.09398 0.36614 1 DataSet_02_198
CTHRC1 MAZ siRNA Haematopoietic_and_lymphoid_tissue K562 0.61818 -0.6939 0.36876 1 DataSet_02_199
CTHRC1 E2F4 siRNA Haematopoietic_and_lymphoid_tissue K562 0.28571 -1.80735 0.09107 1 DataSet_02_200
CTHRC1 TAL1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.33889 -1.56112 0.08944 1 DataSet_02_201
CTHRC1 ZNF384 siRNA Haematopoietic_and_lymphoid_tissue K562 0.54023 -0.88835 0.05443 1 DataSet_02_203
CTHRC1 E2F6 siRNA Haematopoietic_and_lymphoid_tissue K562 2.8125 1.49185 0.85788 1 DataSet_02_205
CTHRC1 ARID2 CRISPR Liver JHH4 6.96777 2.8007 0.199210553879532 1 DataSet_03_015
CTHRC1 ATF3 knockout Colon HCT116 1.71127 0.775072 0.00227881893892849 0.250489610353521 DataSet_03_017
CTHRC1 ATOH8 siRNA Umbilical_vein HUVEC 0.626486 -0.674645 0.107128846421406 0.885272532352317 DataSet_03_019
CTHRC1 BCL6 siRNA Lymph OCI-Ly7 DLBCL 0.652777 -0.615337 0.450146596834459 0.897489797292523 DataSet_03_025
CTHRC1 BCL6 siRNA Lymph Pfeiffer DLBCL 1.51777 0.601949 0.0373672446250364 0.461865115499522 DataSet_03_026
CTHRC1 CEBPA siRNA Mammary_gland MCF7 1.9001 0.926079 0.0287942334255604 0.999962793175751 DataSet_03_047
CTHRC1 CTNNB1 siRNA Mammary_gland MCF7 1.57979 0.659734 0.0897638910178424 0.999436862066063 DataSet_03_058
CTHRC1 E2F7 siRNA Upper_aerodigestive_tract SCC25 2.32254 1.2157 2.65821509799498e-08 3.67896969562506e-06 DataSet_03_063
CTHRC1 GATA4 siRNA Stomach AGS 1.50317 0.588003 0.667038617654735 0.958048054456509 DataSet_03_105
CTHRC1 GATA4 siRNA Stomach YCC3 0.442391 -1.1766 0.0719315137094171 0.616918961213603 DataSet_03_107
CTHRC1 GFP siRNA Upper_aerodigestive_tract SCC25 1.9296 0.9483 1.94169449712347e-06 0.000154798685715374 DataSet_03_112
CTHRC1 HDAC5 siRNA Mammary_gland MCF7 1.81316 0.858506 0.0382403622894921 0.999966625300244 DataSet_03_115
CTHRC1 HIC1 CRISPR Prostate PC3 0.320207 -1.64292 - - DataSet_03_118
CTHRC1 HSF2 siRNA Mammary_gland MCF7 1.74566 0.803771 0.0482644639282251 0.990969613280381 DataSet_03_130
CTHRC1 IRF4 siRNA Skin Cutaneous T cell lymphoma HuT-102 cells 1.61639 0.692773 0.423137089593543 0.999948959532916 DataSet_03_134
CTHRC1 JARID1A siRNA Autonomic_ganglia SKNBE2 0.564093 -0.825994 0.0576383494745039 0.430005611434053 DataSet_03_135
CTHRC1 JUN siRNA Fibroblasts WI38 1.58478 0.664286 8.14960897843888e-05 0.00315434424410617 DataSet_03_140
CTHRC1 JUN siRNA Fibroblasts WI38 1.58478 0.664286 8.13697020316754e-05 0.0031233004034707 DataSet_03_141
CTHRC1 KLF5 siRNA Colon SW480 1.66274 0.73356 3.69247123566268e-05 0.011454920147634 DataSet_03_148
CTHRC1 KLF5 siRNA Stomach AGS 1.64558 0.718595 0.556679925493311 0.861680041926923 DataSet_03_149
CTHRC1 MITF siRNA Skin Ma-Mel-15 1.51309 0.597493 0.0699185294717968 0.382076336466529 DataSet_03_167
CTHRC1 MITF siRNA Skin SK-MEL-5 0.587914 -0.766323 0.000994200831098741 0.00337418756489277 DataSet_03_168
CTHRC1 MYC siRNA Colon HT29 1.58047 0.660353 - - DataSet_03_177
CTHRC1 MYC siRNA Central_nervous_system DAOY M2.1 13.3855 3.7426 4.25137739850961e-12 4.60317887823628e-08 DataSet_03_178
CTHRC1 NFAT5 siRNA Umbilical_vein HUVEC 0.655191 -0.610013 0.112043949953413 0.558446336385846 DataSet_03_195
CTHRC1 NR4A3 siRNA Pancreas 1.1B4 1.67871 0.747355 1.39486411059018e-05 0.000188493315577077 DataSet_03_203
CTHRC1 PCNA siRNA Mammary_gland MCF7 1.78777 0.838164 0.0416845626859493 0.999448838103647 DataSet_03_210
CTHRC1 PHB shRNA Embryo Embryonic stem cells (ESCs) 2.63701 1.3989 2.6315473053257e-05 0.00059733917082629 DataSet_03_211
CTHRC1 RB1 siRNA Mammary_gland MCF7 1.64733 0.720128 0.0691429393032967 0.999890290262508 DataSet_03_219
CTHRC1 RELB siRNA Immortalized_keratinocyte HaCaT 0.561643 -0.832275 0.000329168162855147 0.00333916058959654 DataSet_03_227
CTHRC1 SOX11 siRNA Lung_fibroblast NHLF 1.59258 0.671367 0.19491947496709 0.584162029354128 DataSet_03_237
CTHRC1 SOX11 siRNA Lung_fibroblast NHLF 1.79242 0.841905 0.386443080237726 0.725876003115973 DataSet_03_238
CTHRC1 SOX2 siRNA Lung LK2 1.95972 0.970645 - - DataSet_03_241
CTHRC1 SP1 siRNA Ovary OVSAYO 2.62359 1.39154 0.00144880255341697 0.073585549406873 DataSet_03_251
CTHRC1 STAT5B siRNA Mammary_gland MCF7 1.66216 0.733056 0.0653923841696095 0.999932708473107 DataSet_03_263
CTHRC1 STAT6 siRNA Umbilical_vein HUVEC 1.95615 0.968018 0.0576494866087553 0.742211434311889 DataSet_03_264
CTHRC1 TFAP2C siRNA Mammary_gland MCF7 0.271524 -1.88085 0.0103440426215709 0.268733844625389 DataSet_03_274
CTHRC1 TP53 siRNA Mammary_gland MCF7 1.72944 0.790306 0.0511265690008424 0.999938217444253 DataSet_03_277
CTHRC1 TP53 knockout Haematopoietic_and_lymphoid_tissue MM1S 0.558354 -0.840747 0.608166636510371 0.996741972687817 DataSet_03_279
CTHRC1 WT1 siRNA Mammary_gland MCF7 0.64053 -0.642661 0.0966389661779915 0.999957852801679 DataSet_03_285
CTHRC1 ZHX2 shRNA Kidney 786-O 0.606902 -0.720465 0.000573655705272813 0.0114999538113187 DataSet_03_287
CTHRC1 ZNF554 siRNA Embryo HTR8/Svneo 1.63973 0.713458 1.25776764198221e-08 2.77776159005915e-05 DataSet_03_292
CTHRC1 ZNF750 siRNA Skin Primary neonatal keratinocytes 4.12207 2.04337 4.85214646685695e-05 0.0141172506444072 DataSet_03_294
CTHRC1 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 0.622951 -0.68281 0.61282479137969 0.880944695603171 DataSet_04_001
CTHRC1 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 0.411765 -1.28011 0.00796297570742264 0.0570774567026284 DataSet_04_002
CTHRC1 DDX59 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.52727 0.610958 0.402510960881196 0.711966824482917 DataSet_04_006
CTHRC1 EIF2AK2 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.362319 -1.46467 0.00553750702896526 0.44628950588594 DataSet_04_008
CTHRC1 FUBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.12727 1.089 0.11890392429315 0.225884690225612 DataSet_04_010
CTHRC1 MARK2 shRNA Haematopoietic_and_lymphoid_tissue K562 1.8 0.847997 0.0543760926286175 0.0962678782761748 DataSet_04_012
CTHRC1 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 206.793 7.69204 0.254023179286516 0.401591182323558 DataSet_04_014
CTHRC1 PAN2 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.70909 0.773229 0.108731716703184 0.858378518819642 DataSet_04_016
CTHRC1 RPS3 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.641975 -0.63941 0.00963182077044245 0.387252025537545 DataSet_04_017
CTHRC1 SMAD2 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.64179 0.715271 0.105221608807571 0.230237721605211 DataSet_04_018
CTHRC1 SMAD5 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.663265 -0.592342 0.00323786372204694 0.394951331771279 DataSet_04_020
CTHRC1 XRCC5 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.75556 0.811928 0.0385627764077172 0.239831500207122 DataSet_04_021
CTHRC1 YBX1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.159574 -2.6477 0.0406470139706611 0.497248176954853 DataSet_04_022
CTHRC1 ANXA2 CRISPR Liver HepG2 0.622642 -0.683526 0.123759659372207 0.704095893789967 DataSet_04_024
CTHRC1 E4F1 CRISPR Liver HepG2 0.606956 -0.720335 0.0306485526891365 0.278051624713375 DataSet_04_028
CTHRC1 NFX1 CRISPR Liver HepG2 0.593859 -0.751809 0.00128389826647341 0.0145927460043823 DataSet_04_032
CTHRC1 YBX1 CRISPR Liver HepG2 0.62789 -0.671416 0.310320250342665 0.972884761036538 DataSet_04_039
CTHRC1 ZC3H8 shRNA Liver HepG2 0.527231 -0.923494 0.00733917078749198 0.094527141826364 DataSet_04_040
CTHRC1 DDX20 CRISPR Liver HepG2 0.648373 -0.625103 0.00131679054334758 0.0412891207466856 DataSet_04_043
CTHRC1 DNMT3B CRISPR Liver HepG2 0.652174 -0.616671 0.00273773685156655 0.0750826396899713 DataSet_04_044
CTHRC1 ABT1 shRNA Liver HepG2 2.43047 1.28124 0.000150405252547758 0.00310902476315693 DataSet_04_052
CTHRC1 CNOT7 shRNA Liver HepG2 2.49263 1.31767 0.000170024299825531 0.00320836806862655 DataSet_04_051
CTHRC1 NPM1 shRNA Liver HepG2 1.5616 0.643022 0.0154784769079632 0.322972689747318 DataSet_04_058
CTHRC1 PRPF6 shRNA Liver HepG2 0.455147 -1.1356 0.000410626351059794 0.0306260712278941 DataSet_04_056
CTHRC1 SNW1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.509615 -0.972519 0.0483476327141994 0.121501775143587 DataSet_04_049
CTHRC1 CITED2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.448276 -1.15754 0.21554771215285 0.4796558026202 DataSet_02_38
CTHRC1 DPF2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.55172 1.35147 0.0275816657956659 0.0770186490533306 DataSet_02_14
CTHRC1 ERF CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.586207 -0.770518 0.401488177367162 0.580207975923661 DataSet_02_34
CTHRC1 HMGA1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.218085 -2.19704 0.104393182198694 0.491941511524363 DataSet_02_75
CTHRC1 HMGN3 CRISPRi Haematopoietic_and_lymphoid_tissue K562 3.34483 1.74193 0.0666614422358104 0.533291537886483 DataSet_02_45
CTHRC1 TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.37931 -1.39855 0.153357889665539 0.270704895327429 DataSet_02_33
CTHRC1 ABT1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.8 0.847997 0.118871802839254 0.241412564116493 DataSet_04_060
CTHRC1 CNOT7 shRNA Haematopoietic_and_lymphoid_tissue K562 0.528571 -0.91983 0.546822736821849 0.728778163100246 DataSet_04_061
CTHRC1 DDX1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.280899 -1.83188 0.388805830869565 0.774752738088122 DataSet_04_063
CTHRC1 UBE2L3 shRNA Haematopoietic_and_lymphoid_tissue K562 0.486111 -1.04064 0.0609282537857464 0.232283014432788 DataSet_04_062
CTHRC1 NFAT5 siRNA Umbilical_cords HUASMCs 1.61619 0.692597 8.309366e-05 0.0067462890 DataSet_03_312
CTHRC1 ELF3 CRISPR Bile_duct HBDEC2 1.64735 0.72015 7.194350e-03 2.627337e-02 DataSet_03_304
CTHRC1 SNAI2 shRNA Pancreas pancreatic cancer stem cells 0.63372 -0.658082 6.350264e-01 0.8508011 DataSet_03_306
CTHRC1 SNAI2 shRNA Pancreas KLM1 1.76435 0.819134 2.281029e-01 0.58452109 DataSet_03_307
CTHRC1 PRMT1 shRNA Lung A549 1.54647 0.628981 - - DataSet_03_342
CTHRC1 INO80 siRNA Muscle RD 1.67718 0.74604 - - DataSet_03_344
CTHRC1 TET1 CRISPR Mammary_gland MDA-MB-231 3.22048 1.68728 2.857065e-01 5.043689e-01 DataSet_03_347
CTHRC1 ETV5 knockdown Colon HT29 1.75862 0.814444 1.234480e-01 0.375698943 DataSet_03_353
CTHRC1 NCOA3 siRNA Mammary_gland MDA-MB-231 0.607706 -0.718555 7.248075e-01 0.9732634 DataSet_03_361
CTHRC1 MYC siRNA Peripheral_blood T lymphocyte 2.0053 1.00382 3.350401e-01 0.607825888 DataSet_03_363
CTHRC1 EP300 shRNA Mammary_gland MCF10AT 0.4 -1.32193 2.440122e-02 0.118877699 DataSet_03_364
CTHRC1 TP53 knockout Stomach SNU1 0.525434 -0.928419 0.1008555114 0.9301241 DataSet_03_365
CTHRC1 ZFP36L1 siRNA Urinary_bladder J82 2.28571 1.19265 - - DataSet_03_371
CTHRC1 E2F1 siRNA Nasopharynx HK1 0.230769 -2.11548 1.087820e-01 5.557185e-01 DataSet_03_373
CTHRC1 ZNF213 siRNA Mammary_gland MCF7 2.11641 1.08162 1.836831e-01 6.592819e-01 DataSet_03_376
CTHRC1 EZH2 CRISPR Ovary SKOV3 1.8766 0.908118 1.105261e-03 0.0222591087 DataSet_03_378
CTHRC1 NFKB2 siRNA Bone_marrow U2OS 3 1.58496 3.192182e-03 0.08600455 DataSet_03_381
CTHRC1 DNMT1 siRNA Skin Human melanoma cells 1.50341 0.588243 1.958538e-05 1.669103e-04 DataSet_03_382
CTHRC1 TCF19 CRISPR Oral_squamous CAL27 1.80449 0.851587 2.410696e-03 0.0316894333 DataSet_03_383
CTHRC1 YY1 shRNA Brain GSC1517 0.428571 -1.22239 - - DataSet_03_384
CTHRC1 YY1 shRNA Brain GSC23 0.4 -1.32193 - - DataSet_03_385
CTHRC1 YY1 shRNA Brain GSC3028 4 2 - - DataSet_03_386
CTHRC1 KAT6A CRISPR Haematopoietic_and_lymphoid_tissue MOLM-13 1.65855 0.729927 0.5300607300 0.9002240 DataSet_03_387
CTHRC1 YY1 knockdown Liver HepG2 4.25163 2.08802 1.341106e-12 1.784696e-10 DataSet_03_390
CTHRC1 KDM5A CRISPR Lung GLC16 0.606115 -0.722337 2.764155e-02 0.080916600 DataSet_03_392
CTHRC1 ASXL1 CRISPR Embryo iPSC 3.97442 1.99074 0.0629949434 0.8048302 DataSet_03_394
CTHRC1 BMI1 shRNA Bile_duct QBC-939 2.43455 1.28366 1.937981e-04 0.0027881666 DataSet_03_395
CTHRC1 JAZF1 siRNA Cervix HeLa Kyoto 0.593503 -0.752672 3.372302e-01 0.782417587 DataSet_03_396
CTHRC1 IKZF2 CRISPR Lymph CAR T Cell 7.10843 2.82953 3.396815e-03 0.204454524 DataSet_03_397
CTHRC1 TLE4 CRISPR Lymph CAR T Cell 6.12129 2.61384 8.045186e-04 0.07310924 DataSet_03_398
CTHRC1 RELA CRISPR Brain T30 0.118516 -3.07685 0.2105062777 0.8400824 DataSet_03_399
CTHRC1 SUMO1 CRISPR Bone_marrow U2OS 0.446429 -1.1635 6.399515e-03 4.289530e-02 DataSet_03_401
CTHRC1 JARID2 siRNA Adipose_tissue human adipose tissue derived stem cells 1.5067 0.591391 5.049015e-02 0.3239928 DataSet_03_403
CTHRC1 TFAP2A knockout Embryo H9 0.340073 -1.55608 4.363067e-04 0.02122994 DataSet_03_405
CTHRC1 CHD1 shRNA Prostate LNCaP 0.416667 -1.26303 2.580437e-02 3.585448e-01 DataSet_03_407
CTHRC1 STRAP knockout Nerve SK-N-AS 61.5015 5.94255 - - DataSet_03_409
CTHRC1 SIRT1 siRNA Pancreas PANC1 2.45591 1.29626 3.411362e-04 0.014287020 DataSet_03_410
CTHRC1 USP22 shRNA Liver HuH7 2.34332 1.22855 - - DataSet_03_411
CTHRC1 RUNX2 shRNA Cord_blood Natural Killer Cell 2.79268 1.48165 1.598164e-02 0.793390621 DataSet_03_416
CTHRC1 NFATC2 shRNA Haematopoietic_and_lymphoid_tissue THP-1 0.543478 -0.879706 4.611775e-01 0.653859225 DataSet_03_418
CTHRC1 FOXK2 shRNA Ovary OVCAR-5 0.145969 -2.77626 8.409398e-03 0.09617284 DataSet_03_419
CTHRC1 BRD4 CRISPR Lymph CD8+ T cells 0.507463 -0.978626 - - DataSet_03_420
CTHRC1 PRDM1 CRISPR Lymph CD8+ T cells 0.61194 -0.708537 - - DataSet_03_421
CTHRC1 FOXQ1 CRISPR Lymph Primary CD4+ T cells 1.73404 0.794139 - - DataSet_03_422
CTHRC1 MAEL CRISPR Liver Alexander cells 0.422535 -1.24286 - - DataSet_03_423
CTHRC1 FOXP3 CRISPR Peripheral_blood Naive Treg 0.424242 -1.23704 5.759888e-01 0.805901609 DataSet_03_427
CTHRC1 LHX2 shRNA Bone_marrow ES-derived RPE cells 0.585714 -0.771731 2.456870e-01 1.000000e+00 DataSet_03_428
CTHRC1 STAT3 siRNA Peripheral_blood Monocyte-derived M-CSF macrophages 0.559932 -0.836675 0.5192325532 1 DataSet_03_430
CTHRC1 USP7 shRNA Skin xenograft cells 0.529384 -0.917613 0.32158237 0.4633831 DataSet_03_431
CTHRC1 POU2AF1 CRISPR Haematopoietic_and_lymphoid_tissue OCI-Ly7 0.230769 -2.11548 1.378819e-02 0.348222411 DataSet_03_434
CTHRC1 EP300 knockout Pancreas HPAF-II orthotopic cells 1.94623 0.960684 2.768968e-03 1.640121e-02 DataSet_03_436
CTHRC1 SUFU shRNA Mammary_gland HCC1954 cells 3.61539 1.85415 0.0032937319 0.2904148 DataSet_03_437
CTHRC1 FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 2.47222 1.30581 9.472433e-02 0.90558273 DataSet_03_439
CTHRC1 SETDB1 shRNA Colon HCT116 2.05842 1.04154 - - DataSet_03_440
CTHRC1 HMG20A siRNA Mammary_gland MDA-MB-231 0.614286 -0.703018 0.0115814455 0.1695644 DataSet_03_442
CTHRC1 PHF14 siRNA Mammary_gland MDA-MB-231 0.335714 -1.57469 0.0024545532 0.1688577 DataSet_03_443
CTHRC1 CAMTA1 knockout Embryo_kidney HEK293T 0.4 -1.32193 3.122866e-01 0.44365395 DataSet_03_448
CTHRC1 RELB CRISPR Colon SW480 0.515012 -0.957323 1.636864e-02 1.014519e-01 DataSet_03_449
CTHRC1 CBX2 siRNA Mammary_gland MDA-MB-231 0.64233 -0.638615 1.956015e-02 7.611128e-02 DataSet_03_450
CTHRC1 CBX2 siRNA Mammary_gland MCF7 0.419709 -1.25254 5.051227e-02 0.1092939141 DataSet_03_451
CTHRC1 OGT siRNA Embryo BeWo cells 4 2 4.402495e-01 0.76317389 DataSet_03_453
CTHRC1 SMARCA2 shRNA Lung HCC2302 0.239033 -2.06472 6.646898e-08 2.351029e-07 DataSet_03_455
CTHRC1 ARID1A shRNA Bile_duct MMNK1 0.292814 -1.77194 5.732821e-02 0.266709208 DataSet_03_458
CTHRC1 TXNIP shRNA Cord_blood ST3 0.5625 -0.830075 3.397429e-01 0.5926717116 DataSet_03_462
CTHRC1 SOX9 knockout Liver HuH7 0.147287 -2.7633 1.133422e-04 2.292619e-03 DataSet_03_463
CTHRC1 STAT3 shRNA Liver HepG2 0.428571 -1.22239 4.772477e-01 0.7009938969 DataSet_03_465
CTHRC1 CREBBP CRISPR Lymph U2932 0.649485 -0.622633 9.550731e-01 1.0000000 DataSet_03_474
CTHRC1 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 0.622951 -0.68281 0.4758223 0.8472181 DataSet_04_072
CTHRC1 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 0.411765 -1.28011 0.02231961 0.071350327 DataSet_04_074
Regulation Region
 
T(co)Fs that significantly regulate MYC by the evidences of both expression and ChIP-seq/motif
Expression Atlas of CTHRC1
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines