Gene Overview
Target Gene: PRR5L
NCBI Official Symbol: PRR5L
Entrez ID: 79899
Ensembl ID: ENSG00000135362
Gene Full Name: proline rich 5 like
Strand: +
Gene Locus: 11p13-p12
External Links:

PRR5L Significantly Regulated by These T(co)Fs

T(co)Fs that Activate PRR5L   
T(co)Fs that Repress PRR5L
The Intensity of the Gene Regulated by T(co)Fs:
PRR5L-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
PRR5L HNF1B shRNA Ovary RMG2 1.69408 0.76051 0.00179 0.00677 DataSet_01_103
PRR5L SPDEF shRNA Mammary_gland MCF7 2.75302 1.46102 0.64545 0.99999 DataSet_01_107
PRR5L ZIC2 siRNA Pancreas PANC1 1.64344 0.71672 - - DataSet_01_121
PRR5L FOXM1 siRNA Central_nervous_system U87 2.53245 1.34053 - - DataSet_01_122
PRR5L SF1 siRNA Adrenal_gland H295R/TR 1.59333 0.67205 3.25528e-05 0.00119 DataSet_01_146
PRR5L HSF1 shRNA Skin A375 1.73774 0.79721 0.00367 0.032 DataSet_01_155
PRR5L ELK1 siRNA Peripheral_blood CD4+ T cells 1.88277 0.91285 0.00341 0.02528 DataSet_01_162
PRR5L JUN siRNA Peripheral_blood CD4+ T cells 1.67725 0.7461 0.01311 0.08047 DataSet_01_164
PRR5L MAF siRNA Peripheral_blood CD4+ T cells 1.78226 0.83371 0.00526 0.07221 DataSet_01_165
PRR5L TP63 siRNA Immortalized_keratinocyte HaCaT RG 5.80952 2.53842 - - DataSet_01_196
PRR5L TP63 siRNA Immortalized_keratinocyte HaCaT RG 3.7093 1.89115 - - DataSet_01_197
PRR5L TP63 siRNA Head_and_neck SCC-1 0.12766 -2.96963 - - DataSet_01_198
PRR5L TP63 siRNA Head_and_neck SCC-1 0.23273 -2.10329 - - DataSet_01_199
PRR5L XBP1 shRNA Mammary_gland MDA-MB-231 1.53862 0.62164 0.00045 0.01135 DataSet_01_204
PRR5L HIC1 shRNA Mammary_gland HBL100 2.40283 1.26474 - - DataSet_01_205
PRR5L FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 0.52689 -0.92443 - - DataSet_01_209
PRR5L EGR3 shRNA Prostate M12 0.64391 -0.63507 0.11784 0.34129 DataSet_01_212
PRR5L LIN28A siRNA Embryo H9 3.83062 1.93758 4.20458e-05 0.00188 DataSet_01_215
PRR5L TAL1 shRNA Haematopoietic_and_lymphoid_tissue HEL 1.64906 0.72165 0.00064 0.01158 DataSet_01_217
PRR5L TWIST1 shRNA Stomach CAF32 0.22917 -2.12553 0.00032 0.01506 DataSet_01_253
PRR5L TWIST1 shRNA Stomach CAF 0.46669 -1.09945 0.14034 0.62601 DataSet_01_254
PRR5L STAT5 shRNA Prostate CWR22Pc 2.30946 1.20756 0.00234 0.02326 DataSet_01_279
PRR5L MSX1 siRNA Tooth Dental Pulp Cells 1.52355 0.60744 0.00019 0.00158 DataSet_01_281
PRR5L TFAP4 siRNA Brain BE(2)-C 0.17666 -2.50095 0.32694 0.51625 DataSet_01_295
PRR5L SOX7 siRNA Umbilical_vein HUVEC 0.59965 -0.73782 0.26942 0.89788 DataSet_01_299
PRR5L PTEN shRNA Skin A431 0.50083 -0.99762 0.03153 0.14758 DataSet_01_301
PRR5L ARNT siRNA Upper_aerodigestive_tract HSC3 0.56859 -0.81453 - - DataSet_01_315
PRR5L ELK3 shRNA Mammary_gland MDA-MB-231 0.39867 -1.32674 9.46819e-06 0.00012 DataSet_01_318
PRR5L HOXC6 siRNA Prostate LNCaP 2.8642 1.51813 0.094 0.99927 DataSet_01_333
PRR5L NFE2L2 siRNA Lung A549 3.07848 1.62222 1.87474e-08 4.36909e-06 DataSet_01_335
PRR5L KLF7 siRNA Embryo HCE 0.59413 -0.75116 0.08442 0.6419 DataSet_01_340
PRR5L GATA3 siRNA Oral_cavity OEC-M1 2.67293 1.41842 0.01365 0.68576 DataSet_01_347
PRR5L HIF1A siRNA Oral_cavity OEC-M1 1.66316 0.73393 0.10358 0.85151 DataSet_01_348
PRR5L RBM17 shRNA Liver HepG2 0.5 -1 0.13806 0.40479 DataSet_02_100
PRR5L FIP1L1 shRNA Liver HepG2 29.4286 4.87915 0.00377 0.0257 DataSet_02_103
PRR5L HDGF shRNA Liver HepG2 2.05882 1.04182 0.17403 0.34478 DataSet_02_104
PRR5L U2AF2 shRNA Liver HepG2 8 3 0.39487 0.54212 DataSet_02_105
PRR5L HNRNPUL1 shRNA Liver HepG2 4.42105 2.14439 0.12732 0.20584 DataSet_02_109
PRR5L RBM39 shRNA Liver HepG2 4.75 2.24793 0.10328 0.33436 DataSet_02_111
PRR5L XRCC5 shRNA Liver HepG2 7 2.80735 0.13201 0.31776 DataSet_02_114
PRR5L TARDBP shRNA Liver HepG2 0.42857 -1.22239 0.50652 0.59418 DataSet_02_116
PRR5L SUB1 shRNA Liver HepG2 27 4.75489 0.11516 0.28928 DataSet_02_117
PRR5L RBM34 shRNA Liver HepG2 19 4.24793 0.01191 0.39494 DataSet_02_121
PRR5L EWSR1 shRNA Liver HepG2 0.23529 -2.08746 0.46507 0.58601 DataSet_02_122
PRR5L PCBP2 shRNA Liver HepG2 4 2 0.03363 0.13175 DataSet_02_123
PRR5L FUS shRNA Liver HepG2 30 4.90689 4e-04 0.04604 DataSet_02_124
PRR5L SNRNP70 shRNA Liver HepG2 4.42857 2.14684 0.00791 0.04778 DataSet_02_126
PRR5L SRSF3 shRNA Liver HepG2 2.07143 1.05063 0.00815 0.07884 DataSet_02_127
PRR5L TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 2.125 1.08746 0.93512 0.98021 DataSet_02_129
PRR5L SRSF9 shRNA Haematopoietic_and_lymphoid_tissue K562 2 1 0.50363 0.62986 DataSet_02_134
PRR5L PCBP2 shRNA Haematopoietic_and_lymphoid_tissue K562 3.20833 1.68182 0.06921 0.19192 DataSet_02_135
PRR5L HNRNPK shRNA Haematopoietic_and_lymphoid_tissue K562 2.58333 1.36923 0.02983 0.18704 DataSet_02_136
PRR5L RBFOX2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.15625 -2.67807 0.63936 0.83268 DataSet_02_139
PRR5L RBM34 shRNA Haematopoietic_and_lymphoid_tissue K562 2.16667 1.11548 0.00068 0.20864 DataSet_02_141
PRR5L RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.52381 -0.93289 0.51472 0.5925 DataSet_02_143
PRR5L DROSHA shRNA Haematopoietic_and_lymphoid_tissue K562 0.24561 -2.02554 0.71672 0.87302 DataSet_02_145
PRR5L ILF3 shRNA Haematopoietic_and_lymphoid_tissue K562 1.75 0.80735 0.26538 0.55384 DataSet_02_148
PRR5L NONO shRNA Haematopoietic_and_lymphoid_tissue K562 0.45614 -1.13245 0.78606 0.87714 DataSet_02_149
PRR5L RBM39 shRNA Haematopoietic_and_lymphoid_tissue K562 0.47368 -1.078 0.84898 0.91593 DataSet_02_151
PRR5L ILF2 shRNA Haematopoietic_and_lymphoid_tissue K562 7.125 2.83289 0.97848 1 DataSet_02_152
PRR5L HNRNPUL1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.14035 -2.83289 0.88359 0.95719 DataSet_02_156
PRR5L HNRNPL shRNA Haematopoietic_and_lymphoid_tissue K562 1.8 0.848 0.24275 0.42616 DataSet_02_160
PRR5L TAF15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.47401 0.66888 DataSet_02_163
PRR5L U2AF1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.62963 -0.66742 0.5112 0.66205 DataSet_02_165
PRR5L RBM25 shRNA Haematopoietic_and_lymphoid_tissue K562 0.2037 -2.29546 0.41901 0.62586 DataSet_02_166
PRR5L RBM22 shRNA Haematopoietic_and_lymphoid_tissue K562 1.58333 0.66297 0.08479 0.18572 DataSet_02_168
PRR5L U2AF2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.62963 -0.66742 0.59638 0.70192 DataSet_02_170
PRR5L ZFX siRNA Prostate C4-2B 0.38043 -1.39428 0.01833 0.04889 DataSet_02_172
PRR5L LMNA siRNA Haematopoietic_and_lymphoid_tissue K562 0.41026 -1.2854 0.6788 1 DataSet_02_175
PRR5L CEBPZ siRNA Haematopoietic_and_lymphoid_tissue K562 0.13514 -2.88753 0.03292 1 DataSet_02_176
PRR5L ZNF180 siRNA Haematopoietic_and_lymphoid_tissue K562 3 1.58496 0.13039 1 DataSet_02_177
PRR5L TBL1XR1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.30667 -1.70526 0.11228 1 DataSet_02_178
PRR5L VEZF1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.27119 -1.88264 0.00041 1 DataSet_02_179
PRR5L ATF3 siRNA Haematopoietic_and_lymphoid_tissue K562 5.31818 2.41093 0.67633 1 DataSet_02_180
PRR5L ZMIZ1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.42105 -1.24793 0.60805 1 DataSet_02_181
PRR5L STAT5A siRNA Haematopoietic_and_lymphoid_tissue K562 0.31707 -1.65711 0.01349 1 DataSet_02_182
PRR5L KAT2B siRNA Haematopoietic_and_lymphoid_tissue K562 4.75 2.24793 0.03377 1 DataSet_02_184
PRR5L CTCF siRNA Haematopoietic_and_lymphoid_tissue K562 1.58333 0.66297 0.3152 1 DataSet_02_185
PRR5L BHLHE40 siRNA Haematopoietic_and_lymphoid_tissue K562 6.375 2.67243 0.13227 1 DataSet_02_186
PRR5L CHD1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.875 0.90689 0.80353 1 DataSet_02_187
PRR5L RAD21 siRNA Haematopoietic_and_lymphoid_tissue K562 1.72222 0.78427 0.12269 1 DataSet_02_190
PRR5L ARID3A siRNA Haematopoietic_and_lymphoid_tissue K562 0.34328 -1.54253 0.42858 1 DataSet_02_193
PRR5L TCP1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.61538 -0.70044 0.58743 1 DataSet_02_194
PRR5L LMNB1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.25676 -1.96153 0.60051 1 DataSet_02_195
PRR5L CHD2 siRNA Haematopoietic_and_lymphoid_tissue K562 1.9 0.926 0.62624 0.71529 DataSet_02_196
PRR5L MAZ siRNA Haematopoietic_and_lymphoid_tissue K562 0.26866 -1.89616 0.0854 1 DataSet_02_199
PRR5L E2F4 siRNA Haematopoietic_and_lymphoid_tissue K562 0.53846 -0.89308 0.12206 1 DataSet_02_200
PRR5L TAL1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.47059 -1.08746 0.36666 1 DataSet_02_201
PRR5L BRCA1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.41935 -1.25376 0.47335 1 DataSet_02_202
PRR5L ZNF384 siRNA Haematopoietic_and_lymphoid_tissue K562 0.46667 -1.09954 0.15478 1 DataSet_02_203
PRR5L RCOR1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.38889 -1.36257 0.35521 1 DataSet_02_204
PRR5L ZFX siRNA Mammary_gland MCF7 2.2 1.1375 0.06045 0.22538 DataSet_02_206
PRR5L CEBPB siRNA Embryo hESC 3.54053 1.82396 0.00903408794872066 0.213483494501971 DataSet_03_049
PRR5L ESR1 siRNA Uterus Endometrial stromal cells 0.52045 -0.94217 - - DataSet_03_069
PRR5L FOXO1 siRNA Skin primary human dermal lymphatic endothelial cells 4.90768 2.29504 - - DataSet_03_096
PRR5L GATA4 siRNA Stomach AGS 1.57319 0.653696 0.171559597992452 0.816783035898161 DataSet_03_105
PRR5L GATA6 siRNA Stomach AGS 1.83426 0.875197 0.171148705185224 0.673255130289235 DataSet_03_108
PRR5L GATA6 siRNA Stomach KatoIII 1.56975 0.650537 0.345257267970305 0.8016852631889 DataSet_03_109
PRR5L GATA6 siRNA Stomach YCC3 1.53103 0.614501 0.106389069049633 0.725783835745249 DataSet_03_110
PRR5L HIC1 CRISPR Prostate PC3 3.35811 1.74765 - - DataSet_03_118
PRR5L HNF4a siRNA Liver HepG2 0.601462 -0.733453 0.227857928024163 0.820493522502805 DataSet_03_126
PRR5L MAFB siRNA Peripheral_blood Monocyte-derived M-CSF macrophages 0.607097 -0.72 0.134521171068207 1 DataSet_03_155
PRR5L MEF2D shRNA Liver HuH7 1.64032 0.713976 - - DataSet_03_162
PRR5L MYB siRNA Cord_Blood CD34+ progenitor cells 3.49507 1.80532 - - DataSet_03_170
PRR5L MYC siRNA Colon HT29 2.48473 1.31309 - - DataSet_03_177
PRR5L MYC siRNA Central_nervous_system DAOY M2.1 1.65752 0.729024 5.65821055488658e-07 5.31116383034542e-06 DataSet_03_178
PRR5L PHB shRNA Embryo Embryonic stem cells (ESCs) 8.42846 3.07527 3.52529974236232e-06 0.000239554393660391 DataSet_03_211
PRR5L PRRX1 CRISPR Neuroblastoma 691-MES 0.659994 -0.599474 0.19959179562469 0.89189998148014 DataSet_03_217
PRR5L SOX11 siRNA Lung_fibroblast NHLF 5.27504 2.39918 0.059665743747169 0.413880384134109 DataSet_03_237
PRR5L SOX11 siRNA Lung_fibroblast NHLF 4.29677 2.10325 0.152079346445914 0.528402489053875 DataSet_03_238
PRR5L SOX2 siRNA Mammary_gland GSC-11 0.588801 -0.764147 8.71066461483413e-06 0.0023879948545878 DataSet_03_245
PRR5L SOX9 knockdown Liver HepG2 0.470222 -1.08859 2.24434534125413e-05 0.00121067490051448 DataSet_03_248
PRR5L STAT3 CRISPR Embryo hESC 2.70324 1.43469 0.0414076198938107 0.114066273669743 DataSet_03_258
PRR5L STAT6 siRNA Umbilical_vein HUVEC 1.69709 0.763065 0.0576483524468708 0.742211434311889 DataSet_03_264
PRR5L TP63 siRNA Foreskin Neonatal foreskin keratinocytes 0.571131 -0.808107 0.0595710505027986 0.732269517420315 DataSet_03_282
PRR5L CHCHD3 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.363636 -1.45943 0.144800447088422 0.915844825866729 DataSet_04_003
PRR5L DDX59 CRISPR Haematopoietic_and_lymphoid_tissue K562 3.85714 1.94753 0.0318336657058319 0.518744806039141 DataSet_04_006
PRR5L E4F1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.538462 -0.893085 0.154299379711481 0.586484867122173 DataSet_04_007
PRR5L ERN1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.108471421558088 0.728602866888613 DataSet_04_009
PRR5L FUBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.06667 1.04731 0.220350235070735 0.341406675863748 DataSet_04_010
PRR5L FUBP3 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.85714 0.893085 0.0634673298149017 0.748246762324488 DataSet_04_011
PRR5L MARK2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.468085 -1.09516 0.178051400230876 0.246806268495794 DataSet_04_012
PRR5L NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 11.1759 3.48232 0.0248408816396955 0.0868682624677458 DataSet_04_014
PRR5L RPS3 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.61111 0.688056 0.188036301084667 0.600690297867635 DataSet_04_017
PRR5L SMAD4 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.488372 -1.03395 0.0322573101290859 0.15289467781634 DataSet_04_019
PRR5L XRCC5 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.85714 0.893085 0.592511031807304 0.763542857162388 DataSet_04_021
PRR5L ZNF574 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.315789 -1.66297 0.0313114513432408 0.144542526360072 DataSet_04_023
PRR5L ERN1 CRISPR Liver HepG2 2.5 1.32193 0.0927738562716378 0.25839013792004 DataSet_04_029
PRR5L FUBP1 shRNA Liver HepG2 2 1 0.191780954664508 0.556523711603171 DataSet_04_030
PRR5L MECP2 CRISPR Liver HepG2 2.75 1.45943 0.0806641969852688 0.336272006265506 DataSet_04_031
PRR5L SMAD4 CRISPR Liver HepG2 0.526316 -0.925999 0.456266242985074 0.601437178571569 DataSet_04_035
PRR5L SRPK2 CRISPR Liver HepG2 2.75 1.45943 0.109459275426602 0.291464498258041 DataSet_04_037
PRR5L DDX20 CRISPR Liver HepG2 0.5 -1 0.301098247751924 0.451801589013209 DataSet_04_043
PRR5L CNOT7 CRISPR Liver HepG2 1.75 0.807355 0.52682822532509 0.686394351637525 DataSet_04_045
PRR5L PAN2 CRISPR Liver HepG2 0.526316 -0.925999 0.422935671108238 0.604292436078895 DataSet_04_066
PRR5L RIOK2 CRISPR Liver HepG2 1.66667 0.736966 0.88878037877613 1 DataSet_04_070
PRR5L ABT1 shRNA Liver HepG2 4 2 0.016014305382339 0.0489097346033347 DataSet_04_052
PRR5L DDX1 shRNA Liver HepG2 5.36842 2.4245 0.0551557520765857 0.2176124961275 DataSet_04_057
PRR5L NPM1 shRNA Liver HepG2 3.75 1.90689 0.610682025078045 0.909042112961554 DataSet_04_058
PRR5L PRPF6 shRNA Liver HepG2 13 3.70044 0.361139049988388 0.579665574343417 DataSet_04_056
PRR5L UBE2L3 shRNA Liver HepG2 0.52381 -0.932886 0.504149582623565 0.657797841620137 DataSet_04_055
PRR5L DDX20 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.57143 1.36257 0.390009990934766 0.746766553382657 DataSet_04_050
PRR5L NPM1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.651163 -0.61891 0.173750932112855 0.347549558689645 DataSet_04_046
PRR5L SEPT11 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.444444 -1.16992 0.561885727206108 1 DataSet_04_077
PRR5L SMG7 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.444444 -1.16992 0.56379596754246 0.835452903412517 DataSet_04_075
PRR5L CITED2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.52 -0.943416 0.0780704987927294 0.275696016324913 DataSet_02_38
PRR5L DPF2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.36 -1.47393 0.0629456942519209 0.142014606436417 DataSet_02_14
PRR5L HMGA1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 9.66667 3.27302 0.0692255038639971 0.44602092915716 DataSet_02_75
PRR5L HMGN3 CRISPRi Haematopoietic_and_lymphoid_tissue K562 4.06 2.02148 0.148513277918567 0.642778982091851 DataSet_02_45
PRR5L NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.585 -0.773491 0.291216240571822 0.552162101115945 DataSet_02_32
PRR5L SMARCA4 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.33 -1.59946 0.00623125501636493 0.0285682791850458 DataSet_02_47
PRR5L SNW1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.8913 0.919382 0.23114972147941 0.646349322950611 DataSet_02_49
PRR5L TBL1XR1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.18 -2.47393 0.0111629782044902 0.0550023445847763 DataSet_02_43
PRR5L ABT1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.93333 1.55254 0.222026037475277 0.374602264780574 DataSet_04_060
PRR5L CNOT7 shRNA Haematopoietic_and_lymphoid_tissue K562 0.25 -2 0.67505698062411 0.826093399060223 DataSet_04_061
PRR5L DDX1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.59375 -0.752073 0.669651358139577 0.91779802713623 DataSet_04_063
PRR5L HDGF shRNA Haematopoietic_and_lymphoid_tissue K562 0.446809 -1.16227 0.190405841506742 0.298197304684449 DataSet_04_059
PRR5L NFKBIZ knockout Colon Colon organoid 0.557183 -0.843776 2.077523e-01 0.681837709 DataSet_03_323
PRR5L EZH2 knockdown Uterus Ishikawa (ISK) cell 1.56736 0.648333 - - DataSet_03_324
PRR5L ELF3 CRISPR Bile_duct HBDEC2 4.45905 2.15674 5.933662e-06 2.621833e-04 DataSet_03_304
PRR5L SNAI2 shRNA Pancreas pancreatic cancer stem cells 2.04185 1.02987 1.432198e-01 0.6510154 DataSet_03_306
PRR5L SNAI2 shRNA Pancreas KLM1 0.19802 -2.33628 5.862709e-03 0.14409900 DataSet_03_307
PRR5L INO80 siRNA Muscle RD 1.882 0.912269 - - DataSet_03_344
PRR5L TET1 CRISPR Mammary_gland MDA-MB-231 0.6462 -0.629948 5.117882e-03 3.925566e-02 DataSet_03_347
PRR5L ETV5 knockdown Colon HT29 0.332437 -1.58885 1.617396e-04 0.027628234 DataSet_03_353
PRR5L TET1 CRISPR Mammary_gland Hs578T 2.46495 1.30156 3.685932e-03 2.540753e-02 DataSet_03_355
PRR5L CREBBP CRISPR Brain U5-NPC 1.59574 0.67423 0.2877544332 0.7490853 DataSet_03_356
PRR5L PTPN14 CRISPR Brain U5-NPC 0.526055 -0.926716 9.742130e-02 0.32322579 DataSet_03_357
PRR5L RUNX1 shRNA Haematopoietic_and_lymphoid_tissue OCI-AML5 2.20653 1.14178 6.038749e-02 2.598724e-01 DataSet_03_359
PRR5L NCOA2 siRNA Uterus endometrial stromal cells 0.588491 -0.764907 0.5006652364 1 DataSet_03_360
PRR5L ARID2 shRNA Haematopoietic_and_lymphoid_tissue MM.1S 0.646136 -0.630089 8.995579e-05 5.355889e-04 DataSet_03_362
PRR5L MYC siRNA Peripheral_blood T lymphocyte 0.410652 -1.28401 2.184900e-01 0.508715915 DataSet_03_363
PRR5L EP300 shRNA Mammary_gland MCF10AT 5.67123 2.50366 7.469024e-03 0.062277457 DataSet_03_364
PRR5L BHLHE40 shRNA Cervix HeLaS3 1.62264 0.698344 9.895808e-02 0.84447131 DataSet_03_372
PRR5L E2F1 siRNA Nasopharynx HK1 0.564765 -0.824277 1.012818e-03 2.139855e-02 DataSet_03_373
PRR5L HNRNPU siRNA Colon RKO 0.612141 -0.708065 - - DataSet_03_374
PRR5L ZNF213 siRNA Mammary_gland MCF7 1.87829 0.90942 2.355156e-01 6.592819e-01 DataSet_03_376
PRR5L SMARCA2 shRNA Lung NCI-H1944 0.659191 -0.601231 2.237326e-02 2.936720e-01 DataSet_03_377
PRR5L EZH2 CRISPR Ovary SKOV3 2.95722 1.56424 1.105315e-04 0.0057876515 DataSet_03_378
PRR5L NFKBIA shRNA Bone_marrow U2OS 0.520311 -0.942553 3.368891e-01 0.87005461 DataSet_03_389
PRR5L YY1 knockdown Liver HepG2 26.25 4.71425 1.432966e-05 1.394221e-04 DataSet_03_390
PRR5L PRDM15 CRISPR Kidney Immortalized human podocytes 1.82866 0.870789 2.528691e-01 4.081551e-01 DataSet_03_391
PRR5L ILF2 siRNA Stomach SGC-7901 2.98 1.57531 0.0123896137 0.05383558 DataSet_03_393
PRR5L BMI1 shRNA Bile_duct QBC-939 0.296469 -1.75405 1.321440e-02 0.0482452393 DataSet_03_395
PRR5L TLE4 CRISPR Lymph CAR T Cell 1.56968 0.65047 7.538211e-02 0.30828302 DataSet_03_398
PRR5L RELA CRISPR Brain T30 0.060474 -4.04754 0.2140803826 0.8400824 DataSet_03_399
PRR5L HMGA1 shRNA Bile_duct HUCCT1 2.1354 1.09451 1.068763e-03 0.039058150 DataSet_03_400
PRR5L CDK7 shRNA Bone_marrow D458 3 1.58496 9.704543e-02 0.39312748 DataSet_03_404
PRR5L CHD1 shRNA Prostate LNCaP 0.0851064 -3.55459 4.545527e-01 8.841501e-01 DataSet_03_407
PRR5L MAP3K7 shRNA Prostate LNCaP 0.0595745 -4.06916 2.701875e-01 5.077224e-01 DataSet_03_408
PRR5L STRAP knockout Nerve SK-N-AS 3.16121 1.66048 - - DataSet_03_409
PRR5L E2F1 siRNA Prostate LNCaP 0.5 -1 5.300378e-01 0.8184360010 DataSet_03_413
PRR5L E2F2 siRNA Prostate LNCaP 3.5 1.80736 3.573846e-02 1.553036e-01 DataSet_03_414
PRR5L ZKSCAN3 CRISPR Colon HCT116 0.445946 -1.16506 4.693612e-02 0.417387863 DataSet_03_415
PRR5L NFATC2 shRNA Haematopoietic_and_lymphoid_tissue THP-1 0.660714 -0.597902 2.311167e-01 0.435497894 DataSet_03_418
PRR5L FOXQ1 CRISPR Lymph Primary CD4+ T cells 0.399086 -1.32523 - - DataSet_03_422
PRR5L MAEL CRISPR Liver Alexander cells 0.5 -1 - - DataSet_03_423
PRR5L LHX2 shRNA Bone_marrow ES-derived RPE cells 0.665541 -0.587402 5.812665e-01 1.000000e+00 DataSet_03_428
PRR5L IKZF2 shRNA Lymph Hut78 2.04567 1.03257 1.181200e-01 0.58499277 DataSet_03_429
PRR5L USP7 shRNA Skin xenograft cells 0.483754 -1.04765 0.26367757 0.4348960 DataSet_03_431
PRR5L PLAG1 shRNA Cord_blood Lin-CD34+ HSPCs 0.467933 -1.09563 - - DataSet_03_432
PRR5L SUFU shRNA Mammary_gland HCC1954 cells 3.5 1.80735 0.0026809458 0.2904148 DataSet_03_437
PRR5L CIC knockout Brain Immortalized Astrocyte Cells 0.608525 -0.716613 7.253601e-03 1.599474e-01 DataSet_03_438
PRR5L FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 2.72857 1.44815 8.774692e-03 0.48021655 DataSet_03_439
PRR5L SETDB1 shRNA Colon HCT116 0.248641 -2.00786 - - DataSet_03_440
PRR5L DAXX shRNA Mammary_gland MDA-MB-231 2.50096 1.32248 3.852741e-02 0.21487598 DataSet_03_441
PRR5L CBX2 siRNA Mammary_gland MCF7 0.409001 -1.28982 8.203492e-03 0.0261182422 DataSet_03_451
PRR5L SMARCA2 shRNA Lung HCC2302 0.0618741 -4.01452 2.231248e-17 2.844950e-15 DataSet_03_455
PRR5L PPARG siRNA Aortic_valve Valvular endothelial cell 1.55614 0.637974 1.581790e-05 2.200221e-03 DataSet_03_456
PRR5L ARID1A shRNA Bile_duct MMNK1 1.54019 0.623109 5.986855e-03 0.074149084 DataSet_03_458
PRR5L TXNIP shRNA Cord_Blood CD34+ cells 2.56522 1.35908 - - DataSet_03_461
PRR5L TXNIP shRNA Cord_blood ST3 7.37143 2.88194 1.617212e-03 0.0706648055 DataSet_03_462
PRR5L SOX9 knockout Liver HuH7 0.5 -1 6.413294e-01 7.465250e-01 DataSet_03_463
PRR5L SMARCA1 Cas13 Embryo_kidney HEK293T 0.573529 -0.802061 - - DataSet_03_466
PRR5L SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 1.91176 0.934905 - - DataSet_03_467
PRR5L SMARCA1 shRNA Embryo_kidney HEK293T 2.22059 1.15094 - - DataSet_03_468
PRR5L LIN28A siRNA Mammary_gland MCF7M 0.624734 -0.678687 4.249740e-01 0.7829855 DataSet_03_469
PRR5L LIN28A siRNA Mammary_gland MCF7M 0.624734 -0.678687 4.249740e-01 0.7829855 DataSet_03_470
PRR5L CHCHD3 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.363636 -1.45943 0.2401538 0.8873867 DataSet_04_071
Regulation Region
 
T(co)Fs that significantly regulate FUS by the evidences of both expression and ChIP-seq/motif
Expression Atlas of PRR5L
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines