Gene Overview
Target Gene: AREG
NCBI Official Symbol: AREG
Entrez ID: 374
Ensembl ID: ENSG00000109321
Gene Full Name: amphiregulin
Strand: +
Gene Locus: 4q13.3
External Links:

AREG Significantly Regulated by These T(co)Fs

T(co)Fs that Activate AREG   
T(co)Fs that Repress AREG
The Intensity of the Gene Regulated by T(co)Fs:
AREG-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
AREG SPDEF shRNA Mammary_gland MCF7 0.15429 -2.69626 0.16177 0.99999 DataSet_01_107
AREG HOXA1 siRNA Lung_fibroblast IMR-90 130.769 7.03088 8.42641e-07 0.00345 DataSet_01_110
AREG TCF3 shRNA Mammary_gland MDA-MB468 3.8359 1.93956 9.04096e-05 0.0023 DataSet_01_116
AREG ID1 siRNA Lung A549 0.5497 -0.86328 0.04731 0.23527 DataSet_01_117
AREG IKZF2 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 1.63851 0.71238 0.18026 0.99993 DataSet_01_137
AREG SOX4 shRNA Parotid_gland ACC3 0.60053 -0.73569 0.50725 0.9882 DataSet_01_140
AREG HSF1 shRNA Skin A375 2.04563 1.03254 0.00246 0.02409 DataSet_01_155
AREG ELK1 siRNA Peripheral_blood CD4+ T cells 0.12055 -3.05227 0.00326 0.0245 DataSet_01_162
AREG GATA3 siRNA Peripheral_blood CD4+ T cells 1.79851 0.8468 0.08345 0.41746 DataSet_01_163
AREG JUN siRNA Peripheral_blood CD4+ T cells 0.10952 -3.19074 0.00231 0.02674 DataSet_01_164
AREG MAF siRNA Peripheral_blood CD4+ T cells 0.07936 -3.65543 0.00073 0.02022 DataSet_01_165
AREG NFATC3 siRNA Peripheral_blood CD4+ T cells 0.10071 -3.31172 0.00168 0.03187 DataSet_01_166
AREG NFKB1 siRNA Peripheral_blood CD4+ T cells 406.74 8.66796 0.05443 0.60788 DataSet_01_167
AREG STAT3 siRNA Peripheral_blood CD4+ T cells 0.2953 -1.75974 0.08968 0.99183 DataSet_01_168
AREG CREB1 shRNA Parotid_gland H3118 MEC 0.08723 -3.51901 0.00091 0.10095 DataSet_01_194
AREG TP63 siRNA Head_and_neck SCC-1 0.55813 -0.84134 - - DataSet_01_198
AREG TP63 siRNA Head_and_neck SCC-012 0.49617 -1.01111 - - DataSet_01_201
AREG TP63 siRNA Head_and_neck SCC-6 0.55362 -0.85303 - - DataSet_01_202
AREG XBP1 shRNA Mammary_gland T47D 1.68496 0.75272 5.19351e-05 9e-04 DataSet_01_203
AREG HIC1 shRNA Mammary_gland HBL100 2.43858 1.28604 - - DataSet_01_205
AREG MITF shRNA Skin COLO829 3.94401 1.97966 0.05732 0.20837 DataSet_01_207
AREG REST siRNA Prostate LNCaP 1.53061 0.61411 0.09367 0.34879 DataSet_01_211
AREG LIN28A siRNA Embryo H9 4.74402 2.24611 2.03672e-05 0.00124 DataSet_01_215
AREG TAL1 shRNA Haematopoietic_and_lymphoid_tissue HEL 1.55567 0.63753 0.00665 0.0407 DataSet_01_217
AREG ZEB1 siRNA Cervix HeLa229 2.64318 1.40227 - - DataSet_01_232
AREG STAT5 shRNA Haematopoietic_and_lymphoid_tissue K562 0.43863 -1.18891 3.12931e-05 0.00083 DataSet_01_239
AREG GATA6 siRNA Colon HT29 0.54591 -0.87327 - - DataSet_01_247
AREG TWIST1 shRNA Stomach CAF14 1.66124 0.73226 0.37948 0.99996 DataSet_01_252
AREG TWIST1 shRNA Stomach CAF32 1.87639 0.90796 0.00199 0.02455 DataSet_01_253
AREG TWIST1 shRNA Stomach CAF 1.76554 0.82011 0.14786 0.63094 DataSet_01_254
AREG STAT5 shRNA Prostate CWR22Pc 1.84114 0.8806 0.00394 0.03068 DataSet_01_279
AREG MSX1 siRNA Tooth Dental Pulp Cells 0.15703 -2.67084 7.95005e-07 6.78167e-05 DataSet_01_281
AREG ZIC5 siRNA Skin A375 6.30604 2.65673 - - DataSet_01_284
AREG POSTN shRNA Brain GSC272 2.28828 1.19427 0.18059 0.58498 DataSet_01_293
AREG TFAP4 siRNA Brain BE(2)-C 0.28218 -1.82533 0.42038 0.51625 DataSet_01_295
AREG ARID1B shRNA Liver IRM90 2.10515 1.07392 7.16921e-07 0.00018 DataSet_01_298
AREG SOX7 siRNA Umbilical_vein HUVEC 2.01753 1.01259 0.0559 0.89788 DataSet_01_299
AREG PTEN shRNA Skin A431 0.53687 -0.89737 0.0054 0.0804 DataSet_01_301
AREG ELK3 shRNA Mammary_gland MDA-MB-231 0.05916 -4.07915 1.78197e-06 4.71824e-05 DataSet_01_318
AREG ZNF25 siRNA Bone_marrow hMSC-TERT4 0.49334 -1.01933 0.06894 0.54596 DataSet_01_319
AREG AR shRNA Prostate CWR22Rv1 1.61928 0.69535 0.00179 0.03153 DataSet_01_323
AREG HOXC6 siRNA Prostate LNCaP 1.64096 0.71454 0.79938 0.99927 DataSet_01_333
AREG NFE2L2 siRNA Lung A549 1.87139 0.90411 1.30222e-06 8.95886e-05 DataSet_01_335
AREG HIF1A siRNA Oral_cavity OEC-M1 2.04418 1.03152 0.05896 0.85151 DataSet_01_348
AREG NFYA siRNA Mammary_gland MDA-MB-231 0.63639 -0.65201 - - DataSet_01_355
AREG PAX3 shRNA Soft_tissue Rh30 0.48608 -1.04073 - - DataSet_01_359
AREG SOX17 siRNA Umbilical_vein HUVEC 0.35318 -1.50151 - - DataSet_01_360
AREG RBM17 shRNA Liver HepG2 0.55994 -0.83665 0.03194 0.27426 DataSet_02_100
AREG SAFB2 shRNA Liver HepG2 0.56568 -0.82194 0.00293 0.02618 DataSet_02_102
AREG FIP1L1 shRNA Liver HepG2 4.64152 2.2146 0.00022 0.01016 DataSet_02_103
AREG HDGF shRNA Liver HepG2 1.54932 0.63164 0.07251 0.21148 DataSet_02_104
AREG SSB shRNA Liver HepG2 0.0184 -5.76434 1e-04 0.0037 DataSet_02_107
AREG RBM39 shRNA Liver HepG2 0.6119 -0.70863 0.01936 0.21151 DataSet_02_111
AREG U2AF2 shRNA Liver HepG2 0.63774 -0.64897 0.16769 0.30063 DataSet_02_113
AREG XRCC5 shRNA Liver HepG2 3.78112 1.91881 0.00013 0.12055 DataSet_02_114
AREG PCBP1 shRNA Liver HepG2 9.74908 3.28527 0.00054 0.01339 DataSet_02_115
AREG SUB1 shRNA Liver HepG2 2.85476 1.51337 0.00036 0.12645 DataSet_02_117
AREG CEBPZ shRNA Liver HepG2 0.59172 -0.75702 0.71087 1 DataSet_02_118
AREG RBM25 shRNA Liver HepG2 3.38376 1.75863 0.00364 0.0268 DataSet_02_119
AREG PTBP1 shRNA Liver HepG2 42.4576 5.40795 1e-04 0.00582 DataSet_02_120
AREG EWSR1 shRNA Liver HepG2 1.9926 0.99465 0.04716 0.12721 DataSet_02_122
AREG FUS shRNA Liver HepG2 1.96054 0.97125 0.00129 0.05046 DataSet_02_124
AREG HNRNPLL shRNA Liver HepG2 0.27255 -1.87538 0.00039 0.01127 DataSet_02_125
AREG SNRNP70 shRNA Liver HepG2 0.22379 -2.1598 0.00044 0.03074 DataSet_02_126
AREG SRSF3 shRNA Liver HepG2 1.73855 0.79789 0.04521 0.14953 DataSet_02_127
AREG PRPF4 shRNA Liver HepG2 0.17329 -2.52875 0.00031 0.02426 DataSet_02_128
AREG TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 0.54743 -0.86926 0.00192 0.23905 DataSet_02_129
AREG PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.6615 -0.59619 0.0404 0.0982 DataSet_02_131
AREG AGO2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.31893 -1.64868 0.00534 0.10123 DataSet_02_132
AREG PCBP2 shRNA Haematopoietic_and_lymphoid_tissue K562 1.50093 0.58586 0.00588 0.08614 DataSet_02_135
AREG HNRNPK shRNA Haematopoietic_and_lymphoid_tissue K562 2.0155 1.01114 0.00799 0.15175 DataSet_02_136
AREG PCBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.6646 0.73518 0.0027 0.19546 DataSet_02_137
AREG RBFOX2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.5256 -0.92797 0.02528 0.45829 DataSet_02_139
AREG RBM34 shRNA Haematopoietic_and_lymphoid_tissue K562 1.62244 0.69817 0.04823 0.24143 DataSet_02_141
AREG PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.06699 1.04753 0.00376 0.19727 DataSet_02_144
AREG ILF3 shRNA Haematopoietic_and_lymphoid_tissue K562 0.58362 -0.7769 0.12248 0.40163 DataSet_02_148
AREG ILF2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.54723 -0.86978 0.13756 0.43258 DataSet_02_152
AREG SRSF4 shRNA Haematopoietic_and_lymphoid_tissue K562 2.12317 1.08622 0.074 0.40514 DataSet_02_154
AREG FUS shRNA Haematopoietic_and_lymphoid_tissue K562 1.66692 0.73719 0.02186 0.23697 DataSet_02_155
AREG SUB1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.02412 1.01729 0.08204 0.71289 DataSet_02_161
AREG AGO1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.7013 0.76664 0.03633 0.53443 DataSet_02_162
AREG TAF15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.47403 -1.07695 0.05959 0.29595 DataSet_02_163
AREG U2AF1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.33933 1.22609 0.00065 0.13212 DataSet_02_165
AREG TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 0.6174 -0.69571 0.00207 0.04354 DataSet_02_169
AREG U2AF2 shRNA Haematopoietic_and_lymphoid_tissue K562 1.94457 0.95945 0.00147 0.04371 DataSet_02_170
AREG RAD21 siRNA Haematopoietic_and_lymphoid_tissue K562 0.45619 -1.13228 0.58079 1 DataSet_02_190
AREG AR siRNA Prostate abl cells 1.6039 0.681581 0.215752682491089 0.999852161656754 DataSet_03_004
AREG AR siRNA Mammary_gland MCF7 0.414373 -1.271 0.000104474590932173 0.00343593291974169 DataSet_03_006
AREG ASCL1 siRNA Lung DMS79 0.378578 -1.40134 0.0410377367965804 0.646808950312483 DataSet_03_016
AREG BCL6 siRNA Lymph Pfeiffer DLBCL 2.75491 1.462 0.024015719115148 0.424865592221281 DataSet_03_026
AREG CEBPB siRNA Embryo hESC 0.367954 -1.4424 0.000720123585225396 0.108255836739527 DataSet_03_049
AREG CTNNB1 siRNA Mammary_gland MCF7 1.71967 0.782129 0.0295258273598343 0.999436862066063 DataSet_03_058
AREG E2F1 siRNA Mammary_gland MCF7 1.504 0.588808 0.0778583274803601 0.999927373439084 DataSet_03_061
AREG ETS1 siRNA Fibroblasts WI38 0.433394 -1.20625 0.00476497673224247 0.0442727262344595 DataSet_03_073
AREG ETS1 siRNA Fibroblasts WI38 0.459165 -1.12292 0.0123042249585376 0.0855026654937877 DataSet_03_074
AREG FOXM1 siRNA Mammary_gland BT-20 cells 1.57143 0.652077 0.0183850420240884 0.332893949954201 DataSet_03_091
AREG FOXO1 siRNA Skin primary human dermal lymphatic endothelial cells 0.0249562 -5.32446 - - DataSet_03_096
AREG GATA3 siRNA Mammary_gland MCF7 1.51455 0.598894 0.0739669033824326 0.999831535534034 DataSet_03_102
AREG GATA6 siRNA Stomach AGS 0.5223 -0.937048 0.0563631931815126 0.497572339317429 DataSet_03_108
AREG GATA6 siRNA Stomach KatoIII 1.79441 0.843506 0.172494101818977 0.688704078550501 DataSet_03_109
AREG HNF4a siRNA Liver HepG2 2.31487 1.21093 0.0295295493559935 0.593510961878416 DataSet_03_126
AREG IRF4 siRNA Skin Cutaneous T cell lymphoma HuT-102 cells 0.638533 -0.647167 0.403952330555736 0.999948959532916 DataSet_03_134
AREG Klf4 siRNA Skin Primary neonatal keratinocytes 0.623761 -0.680934 0.00118507822492269 0.010247014734873 DataSet_03_147
AREG KLF5 siRNA Colon SW480 1.63356 0.708022 0.0633917132581256 0.395664527171555 DataSet_03_148
AREG KLF5 siRNA Stomach KatoIII 1.72177 0.78389 0.205447311276637 0.654066675344837 DataSet_03_150
AREG MEF2D shRNA Liver HuH7 3.83915 1.94079 - - DataSet_03_162
AREG MEF2D siRNA Liver HuH7 7.36028 2.87976 - - DataSet_03_163
AREG MTA2 siRNA Stomach SGC-7901 2.00646 1.00466 - - DataSet_03_169
AREG PHB shRNA Embryo Embryonic stem cells (ESCs) 2.39826 1.26199 0.0184796201655851 0.0513441332673524 DataSet_03_211
AREG RELA siRNA Fibroblasts WI38 3.66802 1.875 7.29273401840741e-05 0.0024139719572846 DataSet_03_222
AREG RELA siRNA Fibroblasts WI38 5.15748 2.36667 7.00733144984601e-07 4.29288127550312e-05 DataSet_03_223
AREG SOX11 siRNA Lung_fibroblast NHLF 1.73302 0.793291 0.1123729903209 0.507079106544127 DataSet_03_237
AREG SOX11 siRNA Lung_fibroblast NHLF 2.57419 1.36412 0.12437918904446 0.485108148944027 DataSet_03_238
AREG SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 0.592593 -0.754888 - - DataSet_03_246
AREG SP1 siRNA Cervix HeLa 1.52853 0.612142 0.00269840675030849 0.0176324677664244 DataSet_03_249
AREG STAT1 knockout Liver Huh-7.5 2.30449 1.20445 0.00107882150244022 0.0344778341150287 DataSet_03_257
AREG STAT3 CRISPR Embryo hESC 0.123039 -3.02281 0.00595255657362975 0.0526603967884268 DataSet_03_258
AREG STAT5B siRNA Mammary_gland MCF7 1.57832 0.658385 0.0547136852851446 0.999932708473107 DataSet_03_263
AREG TCEA1 siRNA Mammary_gland MCF7 1.52805 0.611694 0.0693106713230403 0.999762252994287 DataSet_03_266
AREG TFAP2C siRNA Mammary_gland MCF7 2.69863 1.43223 0.0991307589539383 0.448090143066739 DataSet_03_274
AREG TP53 siRNA Mammary_gland MCF7 1.64926 0.721814 0.0397931272420447 0.999938217444253 DataSet_03_277
AREG TP63 siRNA Skin Primary neonatal keratinocytes 0.613176 -0.705628 0.000754885462909007 0.00886499170243739 DataSet_03_281
AREG TP63 siRNA Foreskin Neonatal foreskin keratinocytes 0.562595 -0.829831 0.155889742779799 0.754776896268714 DataSet_03_282
AREG ZHX2 shRNA Kidney 786-O 1.60959 0.686689 0.00282713820738564 0.0270322312573596 DataSet_03_287
AREG ZNF165 siRNA Mammary_gland SUM159 1.75904 0.814787 0.559664739403347 0.999998167536832 DataSet_03_288
AREG ZNF165 siRNA Mammary_gland WHIM12 0.631094 -0.664073 0.148829683170452 0.999997668745677 DataSet_03_289
AREG ZNF746 siRNA Colon HCT116 0.622437 -0.684 - - DataSet_03_293
AREG APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 4.58317 2.19635 0.000494655828242338 0.216938313807236 DataSet_04_001
AREG CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 1.80659 0.85327 0.00477082893082773 0.0507335764981845 DataSet_04_002
AREG CIZ1 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.29499 1.19849 0.00145350445262268 0.020385436043523 DataSet_04_004
AREG EIF2AK2 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.56435 0.645563 0.0509860808065926 0.485121323596656 DataSet_04_008
AREG MARK2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.570984 -0.808477 0.00749097576797944 0.0251687114829476 DataSet_04_012
AREG NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 11.8136 3.56238 0.689413909512673 0.788256350022616 DataSet_04_014
AREG SMAD4 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.30514 1.20485 0.00184750702281507 0.0979887211869635 DataSet_04_019
AREG YBX1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.560748 -0.834576 0.217654554787344 0.603470348541001 DataSet_04_022
AREG ANXA2 CRISPR Liver HepG2 1.61739 0.693669 0.138461676144295 0.715854652855132 DataSet_04_024
AREG CIZ1 CRISPR Liver HepG2 3.22222 1.68806 0.00820630671383557 0.176328357533288 DataSet_04_026
AREG E4F1 CRISPR Liver HepG2 1.82255 0.865956 0.0139570123096682 0.2419957830355 DataSet_04_028
AREG ERN1 CRISPR Liver HepG2 0.557589 -0.842725 0.00294600557967918 0.0696765133205214 DataSet_04_029
AREG NFX1 CRISPR Liver HepG2 1.74275 0.801364 0.0116983793294555 0.0398691658395566 DataSet_04_032
AREG PAN2 CRISPR Liver HepG2 1.72644 0.787798 0.0424087513877342 0.172879927094978 DataSet_04_033
AREG YBX1 CRISPR Liver HepG2 0.0866181 -3.52919 0.287101139518291 0.972884761036538 DataSet_04_039
AREG ZC3H8 shRNA Liver HepG2 0.188778 -2.40524 0.00253015930438587 0.0761318855555147 DataSet_04_040
AREG ACTN4 CRISPR Liver HepG2 0.452692 -1.1434 0.000943930022358379 0.0314049003592783 DataSet_04_042
AREG DDX20 CRISPR Liver HepG2 0.642073 -0.639192 0.00104524732657462 0.0398597783455255 DataSet_04_043
AREG CNOT7 CRISPR Liver HepG2 0.208002 -2.26533 1.00614832942611e-05 0.00817949022430367 DataSet_04_045
AREG CALR shRNA Liver HepG2 3.31954 1.73098 7.24189099991391e-06 0.00191058974100696 DataSet_04_053
AREG CCAR1 shRNA Liver HepG2 0.454096 -1.13893 9.93761800847294e-05 0.00853610795101046 DataSet_04_054
AREG CNOT7 shRNA Liver HepG2 0.112348 -3.15396 1.73595380447284e-06 0.000841644333519409 DataSet_04_051
AREG PRPF6 shRNA Liver HepG2 0.643032 -0.637038 0.00449995796289827 0.0561745580373009 DataSet_04_056
AREG UBE2L3 shRNA Liver HepG2 2.0579 1.04118 0.000125876087062824 0.00610629238896484 DataSet_04_055
AREG YBX3 shRNA Liver HepG2 0.498439 -1.00451 0.000136020858243755 0.0279539922692366 DataSet_02_98
AREG NPM1 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.47589 1.30795 0.000130505075392963 0.0340600577442938 DataSet_04_046
AREG NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.585799 -0.771523 0.0315185964540885 0.350009805091782 DataSet_02_32
AREG TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.50296 0.587805 0.233707608891232 0.375488303804286 DataSet_02_33
AREG ABT1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.551271 -0.859167 0.00651748962613289 0.0428305649476852 DataSet_04_060
AREG CNOT7 shRNA Haematopoietic_and_lymphoid_tissue K562 0.4524 -1.14433 0.0432900457081079 0.158081538714112 DataSet_04_061
AREG HDGF shRNA Haematopoietic_and_lymphoid_tissue K562 0.632124 -0.66172 0.00570317629899584 0.0199154326885348 DataSet_04_059
AREG NFKBIZ knockout Colon Colon organoid 0.392143 -1.35055 5.896172e-02 0.656871251 DataSet_03_323
AREG AEBP1 siRNA Umbilical_vein HUVEC 1.57869 0.65873 7.096321e-01 0.999982779 DataSet_03_300
AREG SMARCA4 siRNA Colon HCT116 1.83944 0.879265 8.876166e-02 9.443045e-01 DataSet_03_301
AREG SMARCA4 siRNA Colon HCT116 2.22956 1.15676 1.988542e-03 0.1301247 DataSet_03_302
AREG SNAI2 shRNA Pancreas pancreatic cancer stem cells 1.52564 0.609415 1.000110e-01 0.6510154 DataSet_03_306
AREG SNAI2 shRNA Pancreas KLM1 0.452446 -1.14418 3.519640e-02 0.25971495 DataSet_03_307
AREG PRMT1 shRNA Lung A549 0.443554 -1.17282 - - DataSet_03_342
AREG ACTR5 siRNA Muscle RD 0.1107 -3.17527 - - DataSet_03_343
AREG INO80 siRNA Muscle RD 0.111229 -3.16839 - - DataSet_03_344
AREG AEBP1 siRNA Central_nervous_system U87MG 2.27208 1.18401 1.067326e-02 0.9347200 DataSet_03_338
AREG BRCA1 siRNA Mammary_gland MCF7 1.50408 0.588884 1.309729e-01 0.9999931 DataSet_03_308
AREG RUNX1 shRNA Haematopoietic_and_lymphoid_tissue OCI-AML5 1.71177 0.77549 2.308302e-01 4.685650e-01 DataSet_03_359
AREG NCOA2 siRNA Uterus endometrial stromal cells 0.584615 -0.77444 0.5061795784 1 DataSet_03_360
AREG EP300 shRNA Mammary_gland MCF10AT 0.6587 -0.602306 8.573462e-03 0.067716203 DataSet_03_364
AREG DNMT3A knockout Embryo_kidney HEK293T 2.33673 1.22449 - - DataSet_03_369
AREG BHLHE40 shRNA Cervix HeLaS3 3.56725 1.83481 3.350198e-01 0.85073934 DataSet_03_372
AREG E2F1 siRNA Nasopharynx HK1 0.626697 -0.67416 2.922264e-03 4.527451e-02 DataSet_03_373
AREG HNRNPU siRNA Colon RKO 2.88831 1.53023 - - DataSet_03_374
AREG ZNF213 siRNA Mammary_gland MCF7 0.560619 -0.834907 2.710979e-04 1.349213e-02 DataSet_03_376
AREG EZH2 CRISPR Ovary SKOV3 128 7 1.747128e-04 0.0076385366 DataSet_03_378
AREG TCF19 CRISPR Oral_squamous CAL27 0.550853 -0.860261 3.626940e-03 0.0403481906 DataSet_03_383
AREG KAT6A CRISPR Haematopoietic_and_lymphoid_tissue MOLM-13 2.98128 1.57593 0.0502163717 0.8388073 DataSet_03_387
AREG TRIM8 siRNA Mammary_gland MCF7 5.10673 2.3524 5.056298e-07 0.0008667661 DataSet_03_388
AREG NFKBIA shRNA Bone_marrow U2OS 0.0614035 -4.02554 8.403634e-01 0.93331375 DataSet_03_389
AREG YY1 knockdown Liver HepG2 8.94444 3.16099 2.349422e-07 4.328699e-06 DataSet_03_390
AREG ILF2 siRNA Stomach SGC-7901 3.2375 1.69488 0.2183302325 0.40346604 DataSet_03_393
AREG ASXL1 CRISPR Embryo iPSC 3.98638 1.99508 0.0597643152 0.8048302 DataSet_03_394
AREG TLE4 CRISPR Lymph CAR T Cell 0.651706 -0.617708 2.343323e-01 0.57808263 DataSet_03_398
AREG HMGA1 shRNA Bile_duct HUCCT1 7.14773 2.83749 1.166989e-04 0.014832233 DataSet_03_400
AREG TFAP2A knockout Embryo H9 0.363636 -1.45943 6.721896e-01 0.76331870 DataSet_03_405
AREG CHD1 shRNA Prostate LNCaP 0.025974 -5.26679 3.084976e-01 8.223830e-01 DataSet_03_407
AREG MAP3K7 shRNA Prostate LNCaP 0.0275974 -5.17932 3.064488e-01 5.399056e-01 DataSet_03_408
AREG STRAP knockout Nerve SK-N-AS 1.9247 0.944631 - - DataSet_03_409
AREG SIRT1 siRNA Pancreas PANC1 0.278395 -1.84479 1.435478e-05 0.007379702 DataSet_03_410
AREG USP22 shRNA Liver HuH7 0.507756 -0.977794 - - DataSet_03_411
AREG E2F2 siRNA Prostate LNCaP 3.66667 1.87447 4.161425e-02 1.703004e-01 DataSet_03_414
AREG RUNX2 shRNA Cord_blood Natural Killer Cell 0.636711 -0.651289 2.328738e-01 0.793390621 DataSet_03_416
AREG FOXK2 shRNA Ovary OVCAR-5 4.82645 2.27096 2.800379e-02 0.13487985 DataSet_03_419
AREG BRD4 CRISPR Lymph CD8+ T cells 0.615385 -0.70044 - - DataSet_03_420
AREG FOXQ1 CRISPR Lymph Primary CD4+ T cells 0.580645 -0.784271 - - DataSet_03_422
AREG MAEL CRISPR Liver Alexander cells 0.130557 -2.93725 - - DataSet_03_423
AREG STAT3 siRNA Peripheral_blood Monocyte-derived M-CSF macrophages 2.30233 1.20309 0.3992077562 1 DataSet_03_430
AREG USP7 shRNA Skin xenograft cells 2.42857 1.28011 0.45214087 0.5751170 DataSet_03_431
AREG EP300 knockout Pancreas HPAF-II orthotopic cells 0.545326 -0.874808 4.494034e-04 4.508438e-03 DataSet_03_436
AREG SUFU shRNA Mammary_gland HCC1954 cells 0.179 -2.48197 0.7427055884 0.9050866 DataSet_03_437
AREG CIC knockout Brain Immortalized Astrocyte Cells 2.19149 1.13191 4.905824e-01 8.280201e-01 DataSet_03_438
AREG FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 3.61387 1.85354 2.238288e-02 0.66957581 DataSet_03_439
AREG DAXX shRNA Mammary_gland MDA-MB-231 0.308091 -1.69857 5.072672e-05 0.02111146 DataSet_03_441
AREG FOSL1 siRNA Prostate MSKPCa3 0.166667 -2.58496 0.4946652798 0.6975529 DataSet_03_445
AREG RELB CRISPR Colon SW480 0.237037 -2.07682 1.353381e-02 9.258112e-02 DataSet_03_449
AREG CBX2 siRNA Mammary_gland MCF7 0.474782 -1.07466 2.267274e-03 0.0099711222 DataSet_03_451
AREG SMARCA2 shRNA Lung HCC2302 92.004 6.52362 6.900453e-12 8.533301e-11 DataSet_03_455
AREG PPARG siRNA Aortic_valve Valvular endothelial cell 1.54404 0.626711 8.852331e-03 1.252857e-01 DataSet_03_456
AREG SREBF2 siRNA Umbilical_vein HUVEC 0.398528 -1.32725 4.810575e-02 3.541262e-01 DataSet_03_457
AREG ARID1A shRNA Bile_duct MMNK1 1.82565 0.868407 2.341211e-03 0.044979639 DataSet_03_458
AREG IRF2 shRNA Cord_Blood CD34+ cells 2.61538 1.38702 - - DataSet_03_460
AREG TXNIP shRNA Cord_Blood CD34+ cells 2.3913 1.2578 - - DataSet_03_461
AREG TXNIP shRNA Cord_blood ST3 12.2268 3.61197 2.635569e-05 0.0090608877 DataSet_03_462
AREG STAT3 shRNA Liver HepG2 0.585366 -0.77259 6.229977e-02 0.3839039655 DataSet_03_465
AREG EZH2 siRNA Prostate LNCaP 0.496565 -1.00995 - - DataSet_03_472
AREG EZH2 siRNA Umbilical_vein HUVEC 2.45455 1.29546 9.572719e-02 0.319444014 DataSet_03_473
AREG CREBBP CRISPR Lymph U2932 3.05085 1.60921 1.005917e-01 1.0000000 DataSet_03_474
AREG EZH2 siRNA Prostate LNCaP 4.18182 2.06413 1.314134e-01 1.0000000 DataSet_03_475
AREG APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 4.58317 2.19635 0.0001035709 0.145569 DataSet_04_072
AREG CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 1.80659 0.85327 0.001130757 0.015133533 DataSet_04_074
Regulation Region
 
T(co)Fs that significantly regulate YBX1 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of AREG
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines