Gene Overview
Target Gene: CYP19A1
NCBI Official Symbol: CYP19A1
Entrez ID: 1588
Ensembl ID: ENSG00000137869
Gene Full Name: cytochrome P450 family 19 subfamily A member 1
Strand: -
Gene Locus: 15q21.2
External Links:

CYP19A1 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate CYP19A1   
T(co)Fs that Repress CYP19A1
The Intensity of the Gene Regulated by T(co)Fs:
CYP19A1-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
CYP19A1 ZIC2 siRNA Pancreas PANC1 2.00126 1.00091 - - DataSet_01_121
CYP19A1 FOXM1 siRNA Central_nervous_system U87 2.09627 1.06783 - - DataSet_01_122
CYP19A1 POLR3A siRNA Mammary_gland MCF7 0.6253 -0.67739 - - DataSet_01_139
CYP19A1 REST siRNA Adrenal_gland H295R/TR 2.23231 1.15854 7.97958e-06 0.00385 DataSet_01_145
CYP19A1 SF1 siRNA Adrenal_gland H295R/TR 0.42467 -1.23558 6.83286e-06 0.00042 DataSet_01_146
CYP19A1 ESRRG siRNA Placenta_tissue Trophoblast cells 0.51014 -0.97103 0.00333 0.06675 DataSet_01_173
CYP19A1 GABPA shRNA Prostate C4-2B 818.525 9.67688 0.23938 0.43934 DataSet_01_190
CYP19A1 GABPA shRNA Prostate LNCaP 727.588 9.50698 0.46552 0.7048 DataSet_01_191
CYP19A1 GATA2 siRNA Prostate LNCaP 0.61925 -0.69141 0.16798 0.28394 DataSet_01_193
CYP19A1 CREB1 shRNA Parotid_gland H3118 MEC 2.18633 1.12851 0.05308 0.33103 DataSet_01_194
CYP19A1 TP63 siRNA Immortalized_keratinocyte HaCaT RG 0.63419 -0.65702 - - DataSet_01_197
CYP19A1 TP63 siRNA Head_and_neck SCC-1 0.28154 -1.8286 - - DataSet_01_198
CYP19A1 TP63 siRNA Immortalized_keratinocyte HaCaT 1.69436 0.76074 - - DataSet_01_200
CYP19A1 TP63 siRNA Head_and_neck SCC-6 1.75901 0.81476 - - DataSet_01_202
CYP19A1 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly10 0.42396 -1.238 - - DataSet_01_208
CYP19A1 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 1.80779 0.85423 - - DataSet_01_209
CYP19A1 LIN28A siRNA Embryo H9 1.5478 0.63022 0.02486 0.08749 DataSet_01_215
CYP19A1 TAL1 shRNA Haematopoietic_and_lymphoid_tissue HEL 1.52761 0.61127 0.00226 0.02171 DataSet_01_217
CYP19A1 HIF1A shRNA Liver HepG2 1.65654 0.72817 6.12578e-06 0.00612 DataSet_01_220
CYP19A1 MYC siRNA White_adipose_tissue Adipose stem cells 0.48252 -1.05133 5.15391e-07 0.00014 DataSet_01_231
CYP19A1 STAT5 shRNA Haematopoietic_and_lymphoid_tissue K562 2.6068 1.38228 6.2316e-06 0.00039 DataSet_01_239
CYP19A1 POSTN shRNA Brain GSC272 2.35644 1.23661 0.1332 0.56088 DataSet_01_293
CYP19A1 TFAP4 siRNA Brain BE(2)-C 0.21539 -2.21495 0.3546 0.51625 DataSet_01_295
CYP19A1 ARNT siRNA Upper_aerodigestive_tract HSC3 1.75129 0.80841 - - DataSet_01_315
CYP19A1 MYC siRNA Colon HCT116 1.80892 0.85513 0.42177 0.49061 DataSet_01_324
CYP19A1 RBM17 shRNA Liver HepG2 0.4567 -1.13067 0.01903 0.26816 DataSet_02_100
CYP19A1 SAFB2 shRNA Liver HepG2 1.76296 0.818 0.00083 0.0224 DataSet_02_102
CYP19A1 FIP1L1 shRNA Liver HepG2 0.19038 -2.39303 0.00399 0.02643 DataSet_02_103
CYP19A1 HDGF shRNA Liver HepG2 0.59147 -0.75761 0.01406 0.10191 DataSet_02_104
CYP19A1 SSB shRNA Liver HepG2 1.75508 0.81154 0.04302 0.07685 DataSet_02_107
CYP19A1 ZNF622 shRNA Liver HepG2 0.42654 -1.22925 0.00201 0.01129 DataSet_02_108
CYP19A1 GTF2F1 shRNA Liver HepG2 0.66005 -0.59936 0.0106 0.22187 DataSet_02_110
CYP19A1 BCLAF1 shRNA Liver HepG2 2.43455 1.28366 0.00343 0.03134 DataSet_02_112
CYP19A1 U2AF2 shRNA Liver HepG2 0.32955 -1.60144 0.04366 0.13324 DataSet_02_113
CYP19A1 PCBP1 shRNA Liver HepG2 0.51783 -0.94944 0.00081 0.01339 DataSet_02_115
CYP19A1 RBM25 shRNA Liver HepG2 0.34113 -1.5516 0.00018 0.02139 DataSet_02_119
CYP19A1 PTBP1 shRNA Liver HepG2 0.56577 -0.82171 0.00431 0.01347 DataSet_02_120
CYP19A1 FUS shRNA Liver HepG2 0.40961 -1.28767 0.00213 0.056 DataSet_02_124
CYP19A1 HNRNPLL shRNA Liver HepG2 10.9495 3.4528 5e-04 0.01168 DataSet_02_125
CYP19A1 SRSF3 shRNA Liver HepG2 0.64431 -0.63418 0.10591 0.2394 DataSet_02_127
CYP19A1 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.32143 1.21501 0.08401 0.16 DataSet_02_131
CYP19A1 AGO2 shRNA Haematopoietic_and_lymphoid_tissue K562 1.54217 0.62496 0.5142 0.66301 DataSet_02_132
CYP19A1 PCBP2 shRNA Haematopoietic_and_lymphoid_tissue K562 3.17857 1.66838 0.39408 0.55245 DataSet_02_135
CYP19A1 HNRNPK shRNA Haematopoietic_and_lymphoid_tissue K562 2.32143 1.21501 0.11524 0.31333 DataSet_02_136
CYP19A1 PCBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.10714 1.07529 0.19672 0.43278 DataSet_02_137
CYP19A1 BCLAF1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.63889 0.71272 0.63338 0.76696 DataSet_02_142
CYP19A1 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.10843 -3.20511 0.34099 0.5701 DataSet_02_144
CYP19A1 DROSHA shRNA Haematopoietic_and_lymphoid_tissue K562 0.42424 -1.23704 0.16552 0.53525 DataSet_02_145
CYP19A1 CCAR2 shRNA Haematopoietic_and_lymphoid_tissue K562 1.93333 0.95109 0.11111 0.54006 DataSet_02_146
CYP19A1 FIP1L1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.41667 -1.26303 0.22143 0.36433 DataSet_02_147
CYP19A1 RBM39 shRNA Haematopoietic_and_lymphoid_tissue K562 0.57576 -0.79647 0.37407 0.55956 DataSet_02_151
CYP19A1 HNRNPUL1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.07071 -3.822 0.01952 0.51515 DataSet_02_156
CYP19A1 XRCC5 shRNA Haematopoietic_and_lymphoid_tissue K562 0.63793 -0.64853 0.59963 0.90031 DataSet_02_159
CYP19A1 HNRNPL shRNA Haematopoietic_and_lymphoid_tissue K562 1.9375 0.9542 0.20048 0.37968 DataSet_02_160
CYP19A1 SSB shRNA Haematopoietic_and_lymphoid_tissue K562 0.21605 -2.21057 0.19748 0.40712 DataSet_02_164
CYP19A1 TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 0.34118 -1.55141 0.26865 0.37438 DataSet_02_169
CYP19A1 U2AF2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.55556 -0.848 0.72754 0.80925 DataSet_02_170
CYP19A1 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 2.55556 1.35364 0.10637 0.30194 DataSet_02_171
CYP19A1 NFE2L2 siRNA Haematopoietic_and_lymphoid_tissue K562 0.44099 -1.18117 0.4113 1 DataSet_02_174
CYP19A1 VEZF1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.4977 -1.00666 0.3157 1 DataSet_02_179
CYP19A1 KAT2B siRNA Haematopoietic_and_lymphoid_tissue K562 0.53991 -0.88922 0.0945 1 DataSet_02_184
CYP19A1 MAFG siRNA Haematopoietic_and_lymphoid_tissue K562 0.44681 -1.16227 0.7555 1 DataSet_02_189
CYP19A1 CHD2 siRNA Haematopoietic_and_lymphoid_tissue K562 0.53614 -0.89931 0.5826 0.67878 DataSet_02_196
CYP19A1 MAZ siRNA Haematopoietic_and_lymphoid_tissue K562 0.63855 -0.64712 0.25272 1 DataSet_02_199
CYP19A1 E2F4 siRNA Haematopoietic_and_lymphoid_tissue K562 0.46939 -1.09115 0.87268 1 DataSet_02_200
CYP19A1 TAL1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.68657 0.75409 0.33555 1 DataSet_02_201
CYP19A1 ZNF384 siRNA Haematopoietic_and_lymphoid_tissue K562 0.64679 -0.62863 0.19122 1 DataSet_02_203
CYP19A1 RCOR1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.64848 -0.62486 0.30007 1 DataSet_02_204
CYP19A1 AR siRNA Prostate LNCaP 1.54702 0.629491 0.0885615972027257 0.111913178084407 DataSet_03_011
CYP19A1 ASCL1 siRNA Lung DMS79 1.52412 0.607979 0.115691112271229 0.782755856488901 DataSet_03_016
CYP19A1 BCL6 siRNA Lymph Pfeiffer DLBCL 0.590989 -0.758797 0.219529706129125 0.691078383805619 DataSet_03_026
CYP19A1 EP300 siRNA Prostate LNCaP 0.538596 -0.892725 0.074327194094984 0.166371917014935 DataSet_03_065
CYP19A1 GATA6 siRNA Stomach KatoIII 1.67183 0.741431 0.075645755803037 0.588244698225451 DataSet_03_109
CYP19A1 HNF4a siRNA Liver HepG2 0.47195 -1.08329 0.00795327081879932 0.463316892527268 DataSet_03_126
CYP19A1 MEF2D siRNA Liver HuH7 1.95094 0.964166 - - DataSet_03_163
CYP19A1 MYB siRNA Cord_Blood CD34+ progenitor cells 12.8428 3.68289 - - DataSet_03_170
CYP19A1 MYC siRNA Colon HT29 0.595889 -0.746884 - - DataSet_03_177
CYP19A1 NCOA3 siRNA Prostate LNCaP 1.74345 0.801948 0.287881162762086 0.527364608901249 DataSet_03_191
CYP19A1 PPARG siRNA Peripheral_blood GM-CSF Macrophage 1.53067 0.614167 0.130827701914932 0.930263907044415 DataSet_03_214
CYP19A1 REST siRNA Adrenal_gland H295R/TR 1.74577 0.803867 0.000380979883762136 0.0577829679187828 DataSet_03_228
CYP19A1 SMARCA4 siRNA Prostate LNCaP 1.55205 0.634178 0.509246075323366 0.901933663660608 DataSet_03_235
CYP19A1 SMARCC1 siRNA Prostate LNCaP 0.603844 -0.727752 0.219818893716323 0.981357430883255 DataSet_03_236
CYP19A1 SOX11 siRNA Lung_fibroblast NHLF 0.502228 -0.993585 0.0350037186392025 0.285742208991672 DataSet_03_238
CYP19A1 SP1 siRNA Mammary_gland MDA-MB-231 0.526008 -0.926843 0.117440571215399 0.413972819854456 DataSet_03_250
CYP19A1 TP53 siRNA Foreskin Neonatal foreskin keratinocytes 0.33311 -1.58593 0.000499941893756277 0.999791649573014 DataSet_03_278
CYP19A1 TP63 siRNA Foreskin Neonatal foreskin keratinocytes 0.557501 -0.842953 0.0238542592733465 0.729684006943091 DataSet_03_282
CYP19A1 ZNF165 siRNA Mammary_gland SUM159 0.491331 -1.02523 0.158624225931261 0.999998167536832 DataSet_03_288
CYP19A1 ZNF746 siRNA Colon HCT116 1.52335 0.60725 - - DataSet_03_293
CYP19A1 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 2.30435 1.20436 0.0135916164810228 0.456728289189746 DataSet_04_001
CYP19A1 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 1.96296 0.973033 0.106280665290228 0.209752220714003 DataSet_04_002
CYP19A1 CHCHD3 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.22222 1.152 0.087930950056358 0.915844825866729 DataSet_04_003
CYP19A1 CIZ1 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.54412 0.626783 0.696612636862531 0.768276436875683 DataSet_04_004
CYP19A1 CTCF CRISPR Haematopoietic_and_lymphoid_tissue K562 3.1875 1.67243 0.0115564318289735 0.332587786395324 DataSet_04_005
CYP19A1 DDX59 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.553571 -0.853159 0.421493046878054 0.722759757795753 DataSet_04_006
CYP19A1 E4F1 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.1875 1.12928 0.0630815808583948 0.502871437557818 DataSet_04_007
CYP19A1 ERN1 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.5625 1.35755 0.00895056328904756 0.521146547504794 DataSet_04_009
CYP19A1 FUBP3 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.642857 -0.63743 0.706030071732859 0.954967243497847 DataSet_04_011
CYP19A1 MARK2 shRNA Haematopoietic_and_lymphoid_tissue K562 2.45205 1.29399 0.0322686244340365 0.0653346318422455 DataSet_04_012
CYP19A1 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 96.7766 6.59659 0.0212649693830235 0.0789545026569844 DataSet_04_014
CYP19A1 PAN2 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.204044259281203 0.866340360689574 DataSet_04_016
CYP19A1 RPS3 CRISPR Haematopoietic_and_lymphoid_tissue K562 3.57143 1.8365 0.12325961866022 0.5272880076124 DataSet_04_017
CYP19A1 SMAD5 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.3125 1.20945 0.0150493874876023 0.394951331771279 DataSet_04_020
CYP19A1 XRCC5 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.485294 -1.04307 0.362765570676857 0.589856905053404 DataSet_04_021
CYP19A1 YBX1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.464286 -1.10691 0.225577286291911 0.60973941829337 DataSet_04_022
CYP19A1 ZNF574 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.193878 -2.36678 0.0342051800202512 0.149170066842891 DataSet_04_023
CYP19A1 APTX CRISPR Liver HepG2 2.6875 1.42627 0.0416231663652247 0.455813913069024 DataSet_04_025
CYP19A1 ERN1 CRISPR Liver HepG2 1.54565 0.62821 0.00193825251194365 0.0615236264318229 DataSet_04_029
CYP19A1 NFX1 CRISPR Liver HepG2 1.76195 0.817174 0.00415014079616643 0.0225009157503295 DataSet_04_032
CYP19A1 SMAD4 CRISPR Liver HepG2 0.612234 -0.707845 0.0012393251513647 0.0603611303910653 DataSet_04_035
CYP19A1 ZC3H8 shRNA Liver HepG2 1.82762 0.869966 0.00441548469774752 0.0846218827846345 DataSet_04_040
CYP19A1 ACTN4 CRISPR Liver HepG2 2.36242 1.24027 0.00720767960267585 0.0507318398050085 DataSet_04_042
CYP19A1 DDX20 CRISPR Liver HepG2 1.56854 0.649427 0.00279800815803948 0.0467332974910807 DataSet_04_043
CYP19A1 PAN2 CRISPR Liver HepG2 0.612234 -0.707845 0.000178615836688589 0.0165824152079675 DataSet_04_066
CYP19A1 ABT1 shRNA Liver HepG2 0.177692 -2.49255 1.76281143952572e-05 0.0013068406551314 DataSet_04_052
CYP19A1 CALR shRNA Liver HepG2 2.89985 1.53598 1.76384009025273e-05 0.00191058974100696 DataSet_04_053
CYP19A1 PRPF6 shRNA Liver HepG2 0.630571 -0.665269 0.00202388310477339 0.0427534178952079 DataSet_04_056
CYP19A1 UBE2L3 shRNA Liver HepG2 1.9932 0.995085 0.00530630051230494 0.0275153098441231 DataSet_04_055
CYP19A1 NPM1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.555556 -0.847997 0.500578512444715 0.685531971468641 DataSet_04_046
CYP19A1 SEPT11 CRISPR Haematopoietic_and_lymphoid_tissue K562 4.82353 2.27009 0.0289383129540612 1 DataSet_04_077
CYP19A1 SMG5 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.05882 1.04182 0.4154245603394 0.765200897673279 DataSet_04_073
CYP19A1 SMG7 CRISPR Haematopoietic_and_lymphoid_tissue K562 6.88235 2.7829 0.14652958214545 0.498336928071079 DataSet_04_075
CYP19A1 SNW1 CRISPR Haematopoietic_and_lymphoid_tissue K562 2 1 0.340616828074927 0.509632807522406 DataSet_04_049
CYP19A1 CITED2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.531915 -0.910733 0.614862744597111 0.808636028117307 DataSet_02_38
CYP19A1 DPF2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.234043 -2.09516 0.352680581460996 0.515329957792942 DataSet_02_14
CYP19A1 ERF CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.170213 -2.55459 0.299792185596133 0.477269406694843 DataSet_02_34
CYP19A1 HMGA1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.464286 -1.10692 0.127770355352537 0.520945272290348 DataSet_02_75
CYP19A1 HMGN3 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.57447 0.654864 0.548787172587321 0.869676036257581 DataSet_02_45
CYP19A1 LDB1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.404255 -1.30666 0.468501445572424 0.649269995520965 DataSet_02_35
CYP19A1 NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.606383 -0.721699 0.614436025153681 0.788119796043452 DataSet_02_32
CYP19A1 SNW1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 4.92308 2.29956 0.122830178478527 0.526326627041528 DataSet_02_49
CYP19A1 TBL1XR1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.70213 0.767339 0.577112452134705 0.744385735422928 DataSet_02_43
CYP19A1 TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.191489 -2.38466 0.325800735234114 0.481586339205956 DataSet_02_33
CYP19A1 ABT1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.555556 -0.847997 0.139706435471765 0.270696043263415 DataSet_04_060
CYP19A1 CNOT7 shRNA Haematopoietic_and_lymphoid_tissue K562 2.12 1.08406 0.173643072104089 0.353881133567333 DataSet_04_061
CYP19A1 HDGF shRNA Haematopoietic_and_lymphoid_tissue K562 0.273973 -1.8679 0.0689989777665659 0.131944557172403 DataSet_04_059
CYP19A1 SNAI2 shRNA Pancreas pancreatic cancer stem cells 1.82037 0.864228 2.284733e-02 0.6279811 DataSet_03_306
CYP19A1 EZH2 knockdown Colon HCT116 1.58781 0.667036 0.140635414 0.8488990 DataSet_03_334
CYP19A1 SKI CRISPR Blood HL60 4 2 4.022023e-01 0.667077595 DataSet_03_351
CYP19A1 ETV5 knockdown Colon HT29 0.363636 -1.45943 1.711708e-01 0.453099797 DataSet_03_353
CYP19A1 TET1 CRISPR Mammary_gland Hs578T 2.39614 1.26071 2.923965e-02 9.974144e-02 DataSet_03_355
CYP19A1 CREBBP CRISPR Brain U5-NPC 2 1 0.8034016069 0.8799256 DataSet_03_356
CYP19A1 RUNX1 shRNA Haematopoietic_and_lymphoid_tissue OCI-AML5 0.0873673 -3.51676 4.105147e-02 2.274392e-01 DataSet_03_359
CYP19A1 NCOA2 siRNA Uterus endometrial stromal cells 0.333333 -1.58496 0.0902486018 1 DataSet_03_360
CYP19A1 MYC siRNA Peripheral_blood T lymphocyte 1.87567 0.907403 2.938246e-02 0.146608965 DataSet_03_363
CYP19A1 EP300 shRNA Mammary_gland MCF10AT 10 3.32193 9.391682e-02 0.268368371 DataSet_03_364
CYP19A1 TPR shRNA Bone_marrow U2OS 1.7462 0.80422 1.952371e-01 6.238032e-01 DataSet_03_370
CYP19A1 ZFP36L1 siRNA Urinary_bladder J82 2.85714 1.51457 - - DataSet_03_371
CYP19A1 BHLHE40 shRNA Cervix HeLaS3 8 3 5.220630e-01 0.91201136 DataSet_03_372
CYP19A1 GLI1 siRNA Skeletal_muscle RMS13 2.32649 1.21815 5.415095e-01 0.707100920 DataSet_03_375
CYP19A1 SMARCA2 shRNA Lung NCI-H1944 0.479109 -1.06158 6.131571e-03 1.911632e-01 DataSet_03_377
CYP19A1 NFKB2 siRNA Bone_marrow U2OS 3.66667 1.87447 1.456083e-01 0.46122143 DataSet_03_381
CYP19A1 DNMT1 siRNA Skin Human melanoma cells 3.03261 1.60056 1.778946e-03 5.059616e-03 DataSet_03_382
CYP19A1 YY1 shRNA Brain GSC1517 12 3.58496 - - DataSet_03_384
CYP19A1 YY1 shRNA Brain GSC23 1.85714 0.893085 - - DataSet_03_385
CYP19A1 YY1 shRNA Brain GSC3028 0.428571 -1.22239 - - DataSet_03_386
CYP19A1 NFKBIA shRNA Bone_marrow U2OS 0.00600848 -7.37878 5.903321e-01 0.87005461 DataSet_03_389
CYP19A1 YY1 knockdown Liver HepG2 0.602459 -0.731065 2.625271e-02 7.798586e-02 DataSet_03_390
CYP19A1 KDM5A CRISPR Lung GLC16 0.404305 -1.30648 1.146988e-03 0.016189280 DataSet_03_392
CYP19A1 JAZF1 siRNA Cervix HeLa Kyoto 0.223108 -2.16418 4.515951e-02 0.620927241 DataSet_03_396
CYP19A1 IKZF2 CRISPR Lymph CAR T Cell 0.448802 -1.15585 5.228097e-01 0.847824801 DataSet_03_397
CYP19A1 RELA CRISPR Brain T30 2.44429 1.28941 0.2879032169 0.8400824 DataSet_03_399
CYP19A1 HMGA1 shRNA Bile_duct HUCCT1 0.0930233 -3.42627 1.970227e-01 0.506128541 DataSet_03_400
CYP19A1 JARID2 siRNA Adipose_tissue human adipose tissue derived stem cells 2.33333 1.22239 2.517619e-01 0.4576066 DataSet_03_403
CYP19A1 CDK7 shRNA Bone_marrow D458 13.2222 3.72489 2.173565e-03 0.09703627 DataSet_03_404
CYP19A1 TFAP2A knockout Embryo H9 0.0618557 -4.01495 2.588639e-05 0.01552045 DataSet_03_405
CYP19A1 SATB2 CRISPR Colon Colon organoid 1.66667 0.736966 2.752356e-01 0.95735254 DataSet_03_406
CYP19A1 STRAP knockout Nerve SK-N-AS 2.44382 1.28914 - - DataSet_03_409
CYP19A1 SIRT1 siRNA Pancreas PANC1 0.6 -0.736966 8.266695e-01 0.893781303 DataSet_03_410
CYP19A1 USP22 shRNA Liver HuH7 6.93208 2.79329 - - DataSet_03_411
CYP19A1 E2F6 shRNA Liver HuH7 0.310408 -1.68776 - - DataSet_03_412
CYP19A1 ZKSCAN3 CRISPR Colon HCT116 1.57143 0.652077 5.603375e-01 0.800961473 DataSet_03_415
CYP19A1 FOXK2 shRNA Ovary OVCAR-5 1.64706 0.719892 1.396007e-01 0.34794422 DataSet_03_419
CYP19A1 BRD4 CRISPR Lymph CD8+ T cells 2.10204 1.07179 - - DataSet_03_420
CYP19A1 PRDM1 CRISPR Lymph CD8+ T cells 0.612245 -0.707819 - - DataSet_03_421
CYP19A1 FOXP3 CRISPR Peripheral_blood Naive Treg 9 3.16992 7.967997e-02 0.378799982 DataSet_03_427
CYP19A1 LHX2 shRNA Bone_marrow ES-derived RPE cells 0.25 -2 3.322884e-02 1.000000e+00 DataSet_03_428
CYP19A1 USP7 shRNA Skin xenograft cells 0.489796 -1.02975 0.29155031 0.4388691 DataSet_03_431
CYP19A1 POU2AF1 CRISPR Haematopoietic_and_lymphoid_tissue OCI-Ly7 2 1 7.862655e-01 0.876297656 DataSet_03_434
CYP19A1 POU2AF1 CRISPR Lymph SUDHL4 0.5 -1 6.786484e-01 0.758567827 DataSet_03_435
CYP19A1 EP300 knockout Pancreas HPAF-II orthotopic cells 22.5 4.49185 3.447291e-02 1.056661e-01 DataSet_03_436
CYP19A1 SUFU shRNA Mammary_gland HCC1954 cells 0.285714 -1.80735 0.3044812930 0.6455297 DataSet_03_437
CYP19A1 SETDB1 shRNA Colon HCT116 1.72136 0.783549 - - DataSet_03_440
CYP19A1 HMG20A siRNA Mammary_gland MDA-MB-231 3.4 1.76553 0.0542730632 0.2564521 DataSet_03_442
CYP19A1 CAMTA1 knockout Embryo_kidney HEK293T 2 1 7.696051e-01 0.84241881 DataSet_03_448
CYP19A1 RELB CRISPR Colon SW480 2.43478 1.28379 2.607076e-02 1.311045e-01 DataSet_03_449
CYP19A1 SOX9 knockout Liver HuH7 2.84946 1.51069 1.774825e-04 2.988451e-03 DataSet_03_463
CYP19A1 PARP1 knockout Embryo_kidney HEK293a 0.66 -0.599462 1.608492e-01 2.904278e-01 DataSet_03_464
CYP19A1 CREBBP CRISPR Lymph U2932 2 1 5.350113e-01 1.0000000 DataSet_03_474
CYP19A1 CHCHD3 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.22222 1.152 0.1096497 0.8578272 DataSet_04_071
CYP19A1 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 2.30435 1.20436 0.04167326 0.4457998 DataSet_04_072
CYP19A1 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 1.96296 0.973033 0.1282336 0.248865738 DataSet_04_074
Regulation Region
 
T(co)Fs that significantly regulate YY1 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of CYP19A1
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines