Gene Overview
Target Gene: HMOX1
NCBI Official Symbol: HMOX1
Entrez ID: 3162
Ensembl ID: ENSG00000100292
Gene Full Name: heme oxygenase 1
Strand: +
Gene Locus: 22q12.3
External Links:

HMOX1 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate HMOX1   
T(co)Fs that Repress HMOX1
The Intensity of the Gene Regulated by T(co)Fs:
HMOX1-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
HMOX1 IRF6 shRNA Fetal_liver Primary CD34+ hematopoietic stem/progenitor cells (HSPCs) 2.14507 1.10102 0.01826 0.10386 DataSet_01_101
HMOX1 MYB shRNA Fetal_liver Primary CD34+ hematopoietic stem/progenitor cells (HSPCs) 1.71873 0.78134 0.00014 0.00065 DataSet_01_102
HMOX1 HNF1B shRNA Ovary RMG2 0.65446 -0.61161 0.04817 0.08956 DataSet_01_103
HMOX1 FOXA1 siRNA Prostate LNCaP 4.6337 2.21216 - - DataSet_01_104
HMOX1 FOXO1 shRNA Bone EWS-FLI1 2.3732 1.24684 0.02523 0.30905 DataSet_01_106
HMOX1 SPDEF shRNA Mammary_gland MCF7 1.62617 0.70147 0.69178 0.99999 DataSet_01_107
HMOX1 GABPA siRNA Lung A549 0.16388 -2.60925 1.07346e-12 1.57055e-09 DataSet_01_113
HMOX1 TCF3 shRNA Mammary_gland MDA-MB468 0.53202 -0.91044 2.40013e-05 0.00091 DataSet_01_116
HMOX1 FOXM1 siRNA Central_nervous_system U87 4.8997 2.29269 - - DataSet_01_122
HMOX1 ZNF91 siRNA Gastrointestinal_tissue GIST-T1 0.64904 -0.62363 0.00038 0.01017 DataSet_01_123
HMOX1 ZNF100 siRNA Gastrointestinal_tissue GIST-T1 1.72287 0.78482 6.61031e-05 0.00527 DataSet_01_124
HMOX1 ZNF254 siRNA Gastrointestinal_tissue GIST-T1 0.46997 -1.08936 4.44679e-06 0.00054 DataSet_01_127
HMOX1 ZNF431 siRNA Gastrointestinal_tissue GIST-T1 2.99894 1.58445 1.68204e-07 1e-04 DataSet_01_128
HMOX1 ID1 shRNA Neuroepithelium GSC8 6.59589 2.72157 7.65167e-15 1.0453e-12 DataSet_01_134
HMOX1 SPDEF shRNA Mammary_gland MCF7 2.59626 1.37644 6.73174e-05 0.01171 DataSet_01_135
HMOX1 POLR3A siRNA Mammary_gland MCF7 0.35101 -1.51041 - - DataSet_01_139
HMOX1 SOX4 shRNA Parotid_gland ACC3 1.89748 0.92408 0.01023 0.83611 DataSet_01_140
HMOX1 ETS2 siRNA Lung H441 1.68179 0.75 7.67555e-07 5e-04 DataSet_01_149
HMOX1 TFAP2C shRNA Mammary_gland MCF7 0.52069 -0.9415 3.067e-06 1.55539e-05 DataSet_01_150
HMOX1 TEAD4 shRNA Stomach SNU216 1.7289 0.78986 - - DataSet_01_151
HMOX1 TAL1 shRNA Umbilical_cord_blood ECFCs 4.25241 2.08828 2.35375e-05 0.12155 DataSet_01_152
HMOX1 STAT1 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 1.56552 0.64665 0.13243 0.42169 DataSet_01_154
HMOX1 HSF1 shRNA Skin A375 0.38147 -1.39036 0.14827 0.38088 DataSet_01_155
HMOX1 MYCN siRNA Autonomic_ganglia SKNBE2 1.98639 0.99015 0.16696 0.48414 DataSet_01_160
HMOX1 ETV1 shRNA Prostate LNCaP 1.50542 0.59017 0.03614 0.10019 DataSet_01_161
HMOX1 ELK1 siRNA Peripheral_blood CD4+ T cells 2.91064 1.54134 0.00399 0.02797 DataSet_01_162
HMOX1 JUN siRNA Peripheral_blood CD4+ T cells 2.67197 1.4179 0.00498 0.0438 DataSet_01_164
HMOX1 MAF siRNA Peripheral_blood CD4+ T cells 2.10773 1.07569 0.02002 0.15791 DataSet_01_165
HMOX1 NFATC3 siRNA Peripheral_blood CD4+ T cells 2.30707 1.20606 0.01595 0.11963 DataSet_01_166
HMOX1 ESRRG siRNA Placenta_tissue Trophoblast cells 1.80969 0.85575 0.07633 0.40145 DataSet_01_173
HMOX1 TP53 siRNA Lung SAECs 2.63035 1.39525 0.23656 0.64762 DataSet_01_175
HMOX1 TP63 shRNA Bladder UC14 5.49941 2.45928 2.59153e-08 6.97572e-06 DataSet_01_183
HMOX1 GATA2 siRNA Prostate LNCaP 0.50546 -0.98432 0.00453 0.01876 DataSet_01_193
HMOX1 CREB1 shRNA Parotid_gland H3118 MEC 0.6497 -0.62215 0.6064 0.84402 DataSet_01_194
HMOX1 CREB1 shRNA Parotid_gland HSY 0.51233 -0.96484 0.01234 0.39989 DataSet_01_195
HMOX1 TP63 siRNA Immortalized_keratinocyte HaCaT 2.01049 1.00755 - - DataSet_01_200
HMOX1 XBP1 shRNA Mammary_gland MDA-MB-231 2.36633 1.24265 0.00654 0.05282 DataSet_01_204
HMOX1 HIC1 shRNA Mammary_gland HBL100 0.56592 -0.82133 - - DataSet_01_205
HMOX1 REST siRNA Prostate LNCaP 1.67871 0.74736 0.06908 0.30528 DataSet_01_211
HMOX1 LIN28A siRNA Embryo H9 3.24809 1.69959 0.00012 0.00327 DataSet_01_215
HMOX1 ATM shRNA Mammary_gland MCF10A 0.59105 -0.75866 6.84972e-06 0.00011 DataSet_01_219
HMOX1 KLF9 siRNA Liver HepG2 2.30487 1.20469 3.23148e-06 6.39593e-05 DataSet_01_222
HMOX1 FOXM1 siRNA Mammary_gland MCF7 2.52792 1.33795 0.00018 0.05012 DataSet_01_223
HMOX1 HIF1A shRNA Liver HuH7 0.59026 -0.76058 - - DataSet_01_224
HMOX1 SNAI2 shRNA Skin Primary human keratinocytes 5.1389 2.36146 9.07038e-05 0.00742 DataSet_01_225
HMOX1 IRX1 shRNA Bone_marrow 143B 1.88303 0.91306 0.0314 0.18451 DataSet_01_227
HMOX1 FOXA1 siRNA Prostate LNCaP 1.9598 0.97071 0.00236 0.09331 DataSet_01_233
HMOX1 FOXP1 siRNA Prostate LNCaP 0.27156 -1.88066 1.21532e-06 0.00731 DataSet_01_234
HMOX1 TWIST1 shRNA Stomach CAF32 0.28817 -1.79499 9.53582e-05 0.01241 DataSet_01_253
HMOX1 TWIST1 shRNA Stomach CAF 0.64941 -0.62281 0.20532 0.67718 DataSet_01_254
HMOX1 SOX4 shRNA Mammary_gland MDA-MB-231 1.51519 0.5995 0.0262 0.20007 DataSet_01_260
HMOX1 FOXO3 siRNA Pancreas PANC1 0.54174 -0.88434 - - DataSet_01_267
HMOX1 SIX4 siRNA Ovary PEO1 0.29587 -1.75698 0.00467 0.04055 DataSet_01_269
HMOX1 SALL4 shRNA Lung H661 2.55831 1.35519 0.00143 0.05011 DataSet_01_277
HMOX1 AR shRNA Prostate CWR22Pc 1.68765 0.75502 0.00076 0.0134 DataSet_01_278
HMOX1 STAT5 shRNA Prostate CWR22Pc 2.98146 1.57602 4.2022e-05 0.00448 DataSet_01_279
HMOX1 MSX1 siRNA Tooth Dental Pulp Cells 2.02806 1.0201 0.00022 0.00172 DataSet_01_281
HMOX1 ZIC5 siRNA Skin A375 3.40357 1.76705 - - DataSet_01_284
HMOX1 ZIC5 siRNA Skin SK-MEL-28 2.15413 1.1071 - - DataSet_01_285
HMOX1 TP53 shRNA Haematopoietic_and_lymphoid_tissue JVM2 3.55038 1.82798 5.75897e-10 5.12605e-08 DataSet_01_286
HMOX1 NFYA shRNA Lung H322 1.57738 0.65753 0.021 0.07266 DataSet_01_288
HMOX1 SNAI2 siRNA Mammary_gland MCFDCIS 2.11141 1.07821 0.01942 0.46999 DataSet_01_292
HMOX1 POSTN shRNA Brain GSC272 2.73794 1.45309 0.06868 0.53976 DataSet_01_293
HMOX1 TFAP4 siRNA Brain BE(2)-C 0.18476 -2.43624 0.45225 0.51643 DataSet_01_295
HMOX1 MYCN siRNA Brain BE(2)-C 1.73986 0.79897 0.74296 1 DataSet_01_296
HMOX1 SOX17 siRNA Umbilical_vein HUVEC 3.09396 1.62946 0.00473 0.99998 DataSet_01_300
HMOX1 PTEN shRNA Skin A431 2.11836 1.08295 0.01276 0.10366 DataSet_01_301
HMOX1 ETV5 siRNA Soft_tissue hADSC 2.0165 1.01185 1.98459e-05 0.00209 DataSet_01_304
HMOX1 ARNT siRNA Upper_aerodigestive_tract HSC3 0.5001 -0.99972 - - DataSet_01_315
HMOX1 MYC siRNA Colon HCT116 2.1563 1.10856 0.05142 0.08262 DataSet_01_324
HMOX1 TOX shRNA Haematopoietic_and_lymphoid_tissue HPB-ALL 2.43751 1.28541 0.0067 0.63404 DataSet_01_332
HMOX1 HOXC6 siRNA Prostate LNCaP 1.69794 0.76378 0.13464 0.99927 DataSet_01_333
HMOX1 NFE2L2 siRNA Lung A549 0.57421 -0.80035 9.48579e-07 7.13117e-05 DataSet_01_335
HMOX1 TCF7L1 shRNA Colon HCT116 0.66159 -0.596 0.00439 0.054 DataSet_01_346
HMOX1 ETV4 shRNA Prostate PC3 1.6926 0.75924 - - DataSet_01_356
HMOX1 PAX3 shRNA Soft_tissue Rh30 2.10732 1.07541 - - DataSet_01_359
HMOX1 SOX17 siRNA Umbilical_vein HUVEC 2.93202 1.55189 - - DataSet_01_360
HMOX1 RBM17 shRNA Liver HepG2 1.57851 0.65857 0.27445 0.54303 DataSet_02_100
HMOX1 RBFOX2 shRNA Liver HepG2 1.61295 0.6897 0.22841 0.677 DataSet_02_101
HMOX1 TAF15 shRNA Liver HepG2 0.14125 -2.8237 3.98628e-05 0.01075 DataSet_02_106
HMOX1 TARDBP shRNA Liver HepG2 0.4938 -1.01799 0.00249 0.02063 DataSet_02_116
HMOX1 RBM25 shRNA Liver HepG2 1.74773 0.80548 0.00318 0.02541 DataSet_02_119
HMOX1 HNRNPLL shRNA Liver HepG2 0.59152 -0.75751 0.00913 0.03175 DataSet_02_125
HMOX1 SNRNP70 shRNA Liver HepG2 0.58389 -0.77623 0.07007 0.15091 DataSet_02_126
HMOX1 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.19048 -2.39232 0.03257 0.07432 DataSet_02_143
HMOX1 SAFB2 shRNA Haematopoietic_and_lymphoid_tissue K562 2 1 0.02854 0.44766 DataSet_02_150
HMOX1 ZFX siRNA Prostate C4-2B 8.62626 3.10873 1.92286e-06 0.00059 DataSet_02_172
HMOX1 NFE2L2 siRNA Haematopoietic_and_lymphoid_tissue K562 0.47368 -1.078 0.18114 1 DataSet_02_174
HMOX1 CEBPZ siRNA Haematopoietic_and_lymphoid_tissue K562 0.23333 -2.09954 0.73476 1 DataSet_02_176
HMOX1 KAT2B siRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.51379 1 DataSet_02_184
HMOX1 CTCF siRNA Haematopoietic_and_lymphoid_tissue K562 1.68421 0.75207 0.62596 1 DataSet_02_185
HMOX1 MAFG siRNA Haematopoietic_and_lymphoid_tissue K562 1.66667 0.73697 0.81954 1 DataSet_02_189
HMOX1 RAD21 siRNA Haematopoietic_and_lymphoid_tissue K562 3.40351 1.76702 0.59803 1 DataSet_02_190
HMOX1 ARID3A siRNA Haematopoietic_and_lymphoid_tissue K562 0.53552 -0.90099 0.21203 1 DataSet_02_193
HMOX1 CDAN1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.83333 0.87447 0.88158 1 DataSet_02_197
HMOX1 UBTF siRNA Haematopoietic_and_lymphoid_tissue K562 0.42 -1.25154 0.14739 1 DataSet_02_198
HMOX1 MAZ siRNA Haematopoietic_and_lymphoid_tissue K562 0.42623 -1.2303 0.08477 1 DataSet_02_199
HMOX1 TAL1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.39474 -1.34104 0.18062 1 DataSet_02_201
HMOX1 ZNF384 siRNA Haematopoietic_and_lymphoid_tissue K562 0.63158 -0.66297 0.19313 1 DataSet_02_203
HMOX1 RCOR1 siRNA Haematopoietic_and_lymphoid_tissue K562 7.25 2.85798 0.25727 1 DataSet_02_204
HMOX1 ZFX siRNA Mammary_gland MCF7 3.20875 1.68201 0.00033 0.02352 DataSet_02_206
HMOX1 AR siRNA Mammary_gland MCF7 1.78482 0.835778 0.000713976108441327 0.0126859641621994 DataSet_03_006
HMOX1 ATF4 siRNA Skin A375 0.486508 -1.03946 0.0456637767215004 0.775512819201899 DataSet_03_018
HMOX1 ATOH8 siRNA Umbilical_vein HUVEC 1.92959 0.948295 0.0121136271929015 0.432872272049972 DataSet_03_019
HMOX1 BCL6 siRNA Central_nervous_system U87 0.426545 -1.22923 3.58059078183842e-06 0.00155281270731378 DataSet_03_027
HMOX1 CASP8AP2 siRNA Bone_marrow U2OS 1.58186 0.661626 8.25610391603559e-07 0.00016454978020835 DataSet_03_031
HMOX1 CEBPB siRNA Embryo hESC 0.423873 -1.23829 0.00536564956712636 0.18868381208857 DataSet_03_049
HMOX1 ETV6 siRNA Central_nervous_system U251 2.56999 1.36177 1.62853099123009e-07 0.00108035203959036 DataSet_03_075
HMOX1 FLI1 siRNA Haematopoietic_and_lymphoid_tissue THP-1 2.30611 1.20546 5.53957805394123e-06 0.0130044112806295 DataSet_03_078
HMOX1 FOXA1 siRNA Mammary_gland MCF7 2.72512 1.44632 5.13798712864036e-07 4.52429760002662e-05 DataSet_03_080
HMOX1 FOXA1 siRNA Mammary_gland MCF7 4.17371 2.06133 4.81117120912121e-16 4.06039380921981e-13 DataSet_03_081
HMOX1 FOXA1 siRNA Mammary_gland MCF7 4.17371 2.06133 4.81117120912121e-16 4.06039380921981e-13 DataSet_03_082
HMOX1 FOXF2 siRNA Mammary_gland MDA-MB-231 3.36529 1.75073 - - DataSet_03_087
HMOX1 FOXM1 siRNA Mammary_gland BT-20 cells 1.57219 0.652778 0.00195978508581661 0.143008675050059 DataSet_03_091
HMOX1 FOXO1 siRNA Skin primary human dermal lymphatic endothelial cells 0.295621 -1.75818 - - DataSet_03_096
HMOX1 GATA2 siRNA Uterus Decidual stromal cells 1.819 0.863145 0.581769571986796 0.951574757739829 DataSet_03_100
HMOX1 GATA6 siRNA Stomach AGS 0.554906 -0.849683 0.00193951502665144 0.149966543870154 DataSet_03_108
HMOX1 GATA6 siRNA Stomach KatoIII 0.586761 -0.769154 0.000487506183845471 0.135345466809919 DataSet_03_109
HMOX1 GFP siRNA Mammary_gland BT-20 cells 1.80749 0.853985 0.00309090193407556 0.263841071216191 DataSet_03_111
HMOX1 GRHL3 siRNA Skin Primary neonatal keratinocytes 0.492737 -1.02111 0.000834791657135061 0.116627450707192 DataSet_03_113
HMOX1 Klf4 siRNA Skin Primary neonatal keratinocytes 0.0102234 -6.61199 1.2932408785461e-06 0.000307748694779294 DataSet_03_147
HMOX1 LHX9 siRNA Skin Fibroblast 0.52382 -0.932857 3.73278578600322e-06 0.00345681469565752 DataSet_03_152
HMOX1 LYAR siRNA Brain BE(2)C cells 2.53174 1.34013 0.0979980208738618 0.412545181927371 DataSet_03_153
HMOX1 MITF siRNA Skin Ma-Mel-15 0.554938 -0.849601 0.0296328385123051 0.25159722472976 DataSet_03_167
HMOX1 MITF siRNA Skin SK-MEL-5 0.471305 -1.08527 2.6240358218696e-06 3.28314810485301e-05 DataSet_03_168
HMOX1 MYB siRNA Cord_Blood CD34+ progenitor cells 4.33293 2.11535 - - DataSet_03_170
HMOX1 MYC siRNA Central_nervous_system DAOY M2.1 2.02069 1.01485 2.28992028911944e-06 1.52955656572737e-05 DataSet_03_178
HMOX1 MYC siRNA Mammary_gland MCF7 1.59693 0.675299 0.00871929457349493 0.999887767096734 DataSet_03_182
HMOX1 MYCN siRNA Autonomic_ganglia SKNBE2 1.98639 0.99015 0.163904913779122 0.494048444969718 DataSet_03_185
HMOX1 MYCN siRNA Brain BE(2)C cells 1.54007 0.623 - - DataSet_03_187
HMOX1 NFAT5 siRNA Umbilical_vein HUVEC 6.55647 2.71292 7.84193468872161e-10 6.53450304552841e-06 DataSet_03_195
HMOX1 NFKB1 siRNA Central_nervous_system U251 2.21369 1.14645 3.82916053861761e-07 0.00206123711793786 DataSet_03_197
HMOX1 NR4A3 siRNA Pancreas 1.1B4 0.630542 -0.665336 0.0512788460801147 0.110778415217914 DataSet_03_203
HMOX1 PHB shRNA Embryo Embryonic stem cells (ESCs) 15.8721 3.98842 4.52890861178836e-07 0.000113292240005626 DataSet_03_211
HMOX1 RELB siRNA Pancreas MIA PaCa-2 1.61504 0.691572 0.00823092844277584 0.083444214534918 DataSet_03_225
HMOX1 RELB shRNA Ovary SKOV3 1.65254 0.724685 0.329502539321141 0.999733815028798 DataSet_03_226
HMOX1 SOX11 siRNA Lung_fibroblast NHLF 1.92109 0.941925 0.0192861090201461 0.320971602420634 DataSet_03_237
HMOX1 SOX11 siRNA Lung_fibroblast NHLF 1.51592 0.600192 0.160291760787246 0.532214789801003 DataSet_03_238
HMOX1 SOX2 siRNA Lung H520 4.62648 2.20991 - - DataSet_03_240
HMOX1 SOX2 siRNA Lung LK2 4.95615 2.30922 - - DataSet_03_241
HMOX1 SOX2 siRNA Embryo 2102Ep 0.643261 -0.636523 0.000253113300354877 0.0070235169792156 DataSet_03_242
HMOX1 SOX2 siRNA Embryo NTera-2 0.656457 -0.607227 0.000511351216349381 0.0214114526399819 DataSet_03_243
HMOX1 SOX4 siRNA Mammary_gland MDA-LM2 1.53576 0.618955 0.32225606153688 0.864114616196884 DataSet_03_247
HMOX1 SRF siRNA Prostate LNCaP 2.88158 1.52686 0.00749267106336084 0.0481037034915739 DataSet_03_254
HMOX1 STAT3 CRISPR Embryo hESC 0.284361 -1.8142 0.0185233363930307 0.0808176213184897 DataSet_03_258
HMOX1 STAT3 siRNA Ovary SKOV3 1.80097 0.848772 1.04652664980525e-05 0.00557223851679406 DataSet_03_261
HMOX1 STAT6 siRNA Umbilical_vein HUVEC 2.87272 1.52242 0.044388234467468 0.709916704130738 DataSet_03_264
HMOX1 TBX3 siRNA Skin Fibroblast 1.75298 0.809808 6.87307023369982e-05 0.00374729525371172 DataSet_03_265
HMOX1 TCEA1 siRNA Mammary_gland MCF7 1.53767 0.620746 0.0127654356117634 0.999762252994287 DataSet_03_266
HMOX1 TET2 siRNA Prostate DU145 2.6932 1.42932 - - DataSet_03_271
HMOX1 TP63 siRNA Skin Primary neonatal keratinocytes 0.226469 -2.14261 1.3861262015187e-05 0.0013489479831662 DataSet_03_281
HMOX1 TWIST1 siRNA Bone_marrow MSCs 10.0903 3.3349 - - DataSet_03_283
HMOX1 ZHX2 shRNA Kidney 786-O 1.52696 0.610665 0.00041512126117629 0.010345486022531 DataSet_03_287
HMOX1 ZNF746 siRNA Colon HCT116 1.66094 0.732 - - DataSet_03_293
HMOX1 ZNF750 siRNA Skin Primary neonatal keratinocytes 0.043066 -4.53731 0.000712563574867264 0.0270711652872817 DataSet_03_294
HMOX1 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 0.571429 -0.807355 0.348807579388594 0.767154857434309 DataSet_04_001
HMOX1 CIZ1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.6 -0.736966 0.607499709016683 0.690113201842291 DataSet_04_004
HMOX1 XRCC5 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.6 -0.736966 0.610741485574987 0.775852442645916 DataSet_04_021
HMOX1 ACTN4 CRISPR Liver HepG2 0.295258 -1.75995 0.00120045492399187 0.0314387418505503 DataSet_04_042
HMOX1 CALR shRNA Liver HepG2 0.503005 -0.991355 0.000143354597667521 0.00412601669171458 DataSet_04_053
HMOX1 PRPF6 shRNA Liver HepG2 1.79765 0.846113 0.00234290595387463 0.0443507986707146 DataSet_04_056
HMOX1 UBE2L3 shRNA Liver HepG2 0.531511 -0.911828 0.000821819522641141 0.0105513750294578 DataSet_04_055
HMOX1 DDX17 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.5 1.32193 0.751528959342821 0.963554930785977 DataSet_04_047
HMOX1 DDX20 CRISPR Haematopoietic_and_lymphoid_tissue K562 7 2.80735 0.21213359216947 0.594245250407483 DataSet_04_050
HMOX1 SMG5 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.526316 -0.925999 0.555343280178171 0.850358615417366 DataSet_04_073
HMOX1 SMG7 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.578947 -0.788496 0.624936269885948 0.868282661580703 DataSet_04_075
HMOX1 CITED2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.66129 0.732304 0.740217900353326 0.886300418741338 DataSet_02_38
HMOX1 DPF2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.403226 -1.31034 0.221679374047175 0.36794626812659 DataSet_02_14
HMOX1 ERF CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.483871 -1.04731 0.342712936272458 0.521361169010229 DataSet_02_34
HMOX1 HMGA1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.58462 1.36995 0.0461429443049841 0.41130799214458 DataSet_02_75
HMOX1 HMGN3 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.72581 1.44668 0.154688643803493 0.64639629083159 DataSet_02_45
HMOX1 LDB1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.370968 -1.43063 0.195982478146842 0.345901333034844 DataSet_02_35
HMOX1 NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 4.96774 2.31259 0.320978307181696 0.575709324619515 DataSet_02_32
HMOX1 SMARCA4 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.322581 -1.63227 0.21509363480502 0.360268270278859 DataSet_02_47
HMOX1 TBL1XR1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.16129 -2.63227 0.101570296360317 0.228423961125142 DataSet_02_43
HMOX1 TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.0645161 -3.9542 0.069589668268538 0.146289869998233 DataSet_02_33
HMOX1 TLE2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.77419 0.827163 0.571806016169975 0.722106180422193 DataSet_02_53
HMOX1 ABT1 shRNA Haematopoietic_and_lymphoid_tissue K562 4 2 0.401356336956437 0.565026216552057 DataSet_04_060
HMOX1 SMARCB1 shRNA Liver SK-Hep1 2.17425 1.12052 0.0046145224 0.8770521 DataSet_03_313
HMOX1 EZH2 shRNA Colon SW480 3.30558 1.7249 - - DataSet_03_298
HMOX1 TET1 siRNA Lung A549 4.0309 2.0111 - - DataSet_03_318
HMOX1 TET1 siRNA Lung A549 4.0309 2.0111 - - DataSet_03_320
HMOX1 ZNF598 knockout Cervix HeLa 0.662249 -0.594554 1.320372e-01 1.0000000 DataSet_03_299
HMOX1 EZH2 knockdown Uterus Ishikawa (ISK) cell 2.35472 1.23556 - - DataSet_03_324
HMOX1 SMARCA4 siRNA Colon HCT116 1.60772 0.685012 1.774498e-01 9.892536e-01 DataSet_03_301
HMOX1 SMARCA4 siRNA Colon HCT116 2.02652 1.01901 2.890663e-03 0.1301247 DataSet_03_302
HMOX1 ELF3 CRISPR Bile_duct HBDEC2 1.5446 0.627235 8.831398e-04 5.576626e-03 DataSet_03_304
HMOX1 HDAC5 siRNA Liver human hepatocytes 0.399724 -1.32292 1.936733e-08 1.232328e-05 DataSet_03_346
HMOX1 INO80 siRNA Muscle RD 1.63631 0.710448 - - DataSet_03_344
HMOX1 EZH2 shRNA Mammary_gland MCF7 1.50427 0.589065 8.629293e-03 1.213836e-01 DataSet_03_331
HMOX1 BCL3 siRNA Central_nervous_system U87 4.08002 2.02858 1.831984e-12 5.757009e-08 DataSet_03_336
HMOX1 DNMT1 shRNA Lung hTERT-immortalised adult fibroblasts 1.78728 0.837763 1.100286e-01 6.204725e-01 DataSet_03_311
HMOX1 ZFX siRNA Prostate C4-2B 9.1308 3.19074 1.697736e-08 1.184607e-05 DataSet_03_348
HMOX1 ZFX siRNA Mammary_gland MCF7 3.30228 1.72346 1.330169e-06 3.653015e-04 DataSet_03_349
HMOX1 SKI CRISPR Blood HL60 4.5 2.16992 4.326430e-03 0.130220805 DataSet_03_351
HMOX1 ESR1 siRNA Mammary_gland MCF7 0.518677 -0.947092 1.544265e-03 0.0233790263 DataSet_03_352
HMOX1 PARP1 siRNA Prostate LNCaP 2.9102 1.54112 2.286969e-01 0.525200649 DataSet_03_354
HMOX1 CREBBP CRISPR Brain U5-NPC 2.14535 1.10121 0.6245958876 0.7637169 DataSet_03_356
HMOX1 PTPN14 CRISPR Brain U5-NPC 0.507984 -0.977146 1.387194e-01 0.36467515 DataSet_03_357
HMOX1 TP53 CRISPR Brain U5-NPC 2.71366 1.44024 2.550582e-02 1.657288e-01 DataSet_03_358
HMOX1 RUNX1 shRNA Haematopoietic_and_lymphoid_tissue OCI-AML5 0.331425 -1.59324 7.788881e-03 1.307468e-01 DataSet_03_359
HMOX1 ARID2 shRNA Haematopoietic_and_lymphoid_tissue MM.1S 4.5415 2.18317 1.005622e-08 4.423000e-06 DataSet_03_362
HMOX1 EP300 shRNA Mammary_gland MCF10AT 6.0181 2.58931 5.249493e-04 0.019179932 DataSet_03_364
HMOX1 TP53 knockout Stomach SNU1 0.588751 -0.764271 0.4266710834 0.9354741 DataSet_03_365
HMOX1 ZNF148 shRNA Mammary_gland MDA-MB-231 1.96991 0.978128 8.177297e-04 0.026572906 DataSet_03_366
HMOX1 TPR shRNA Bone_marrow U2OS 5.02898 2.33027 5.766610e-04 2.635797e-02 DataSet_03_370
HMOX1 ZFP36L1 siRNA Urinary_bladder J82 2.3595 1.23848 - - DataSet_03_371
HMOX1 E2F1 siRNA Nasopharynx HK1 2.51018 1.32779 3.661839e-03 5.341822e-02 DataSet_03_373
HMOX1 GLI1 siRNA Skeletal_muscle RMS13 3.82166 1.9342 6.350528e-05 0.005808475 DataSet_03_375
HMOX1 SMARCA2 shRNA Lung NCI-H1944 1.75247 0.809388 2.526467e-02 3.066364e-01 DataSet_03_377
HMOX1 EZH2 CRISPR Ovary SKOV3 0.590423 -0.760178 1.035717e-01 0.2808671999 DataSet_03_378
HMOX1 DDX5 shRNA Stomach HGC-27 1.86969 0.902802 - - DataSet_03_379
HMOX1 NFKB2 siRNA Bone_marrow U2OS 3.05759 1.6124 3.208658e-04 0.05603913 DataSet_03_381
HMOX1 YY1 shRNA Brain GSC1517 2.4053 1.26622 - - DataSet_03_384
HMOX1 YY1 shRNA Brain GSC3028 1.73256 0.792904 - - DataSet_03_386
HMOX1 KAT6A CRISPR Haematopoietic_and_lymphoid_tissue MOLM-13 1.83837 0.878429 0.1919769317 0.8388073 DataSet_03_387
HMOX1 TRIM8 siRNA Mammary_gland MCF7 4.22686 2.07959 2.091090e-03 0.0195065326 DataSet_03_388
HMOX1 NFKBIA shRNA Bone_marrow U2OS 0.647421 -0.627223 6.195665e-02 0.87005461 DataSet_03_389
HMOX1 KDM5A CRISPR Lung GLC16 1.87257 0.905022 1.822674e-01 0.314435328 DataSet_03_392
HMOX1 ILF2 siRNA Stomach SGC-7901 1.79274 0.842166 0.3046496465 0.50566494 DataSet_03_393
HMOX1 TLE4 CRISPR Lymph CAR T Cell 1.5745 0.654891 1.729100e-01 0.49157314 DataSet_03_398
HMOX1 RELA CRISPR Brain T30 1.50232 0.587192 0.1933860074 0.8400824 DataSet_03_399
HMOX1 EHF shRNA Stomach MKN7 8.34829 3.06148 - - DataSet_03_402
HMOX1 CDK7 shRNA Bone_marrow D458 80.6 6.33271 8.472483e-06 0.01744429 DataSet_03_404
HMOX1 TFAP2A knockout Embryo H9 0.286017 -1.80583 3.464279e-04 0.01975251 DataSet_03_405
HMOX1 E2F1 siRNA Prostate LNCaP 1.52273 0.606658 2.198650e-02 0.4265296107 DataSet_03_413
HMOX1 E2F2 siRNA Prostate LNCaP 2.48011 1.31041 9.913180e-05 3.560410e-03 DataSet_03_414
HMOX1 ZKSCAN3 CRISPR Colon HCT116 1.51741 0.601607 1.029010e-01 0.482108704 DataSet_03_415
HMOX1 FOXK2 shRNA Ovary OVCAR-5 0.339701 -1.55766 5.125133e-02 0.18613973 DataSet_03_419
HMOX1 PRDM1 CRISPR Lymph CD8+ T cells 0.584795 -0.773996 - - DataSet_03_421
HMOX1 FOXP3 CRISPR Peripheral_blood Naive Treg 0.330638 -1.59668 6.029785e-02 0.338625750 DataSet_03_427
HMOX1 LHX2 shRNA Bone_marrow ES-derived RPE cells 4.17225 2.06083 4.915069e-02 1.000000e+00 DataSet_03_428
HMOX1 IKZF2 shRNA Lymph Hut78 0.415865 -1.26581 8.831800e-02 0.53076795 DataSet_03_429
HMOX1 USP7 shRNA Skin xenograft cells 0.458337 -1.12552 0.26693556 0.4348960 DataSet_03_431
HMOX1 NFE2L1 knockout Lung A549 0.336107 -1.57301 2.661617e-03 1.423927e-01 DataSet_03_433
HMOX1 POU2AF1 CRISPR Haematopoietic_and_lymphoid_tissue OCI-Ly7 2.42648 1.27886 1.715540e-03 0.158576807 DataSet_03_434
HMOX1 POU2AF1 CRISPR Lymph SUDHL4 0.6 -0.736966 5.562401e-01 0.646243906 DataSet_03_435
HMOX1 SUFU shRNA Mammary_gland HCC1954 cells 2.27801 1.18777 0.3121593125 0.6455297 DataSet_03_437
HMOX1 FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 1.83966 0.87944 1.379335e-01 0.90558273 DataSet_03_439
HMOX1 SETDB1 shRNA Colon HCT116 6.11547 2.61246 - - DataSet_03_440
HMOX1 CAMTA1 knockout Embryo_kidney HEK293T 0.656942 -0.606162 8.896170e-03 0.11146167 DataSet_03_448
HMOX1 CBX2 siRNA Mammary_gland MDA-MB-231 1.56401 0.645251 9.230283e-01 9.573424e-01 DataSet_03_450
HMOX1 SMARCA2 shRNA Lung HCC2302 0.426132 -1.23063 2.090807e-07 6.495993e-07 DataSet_03_455
HMOX1 PPARG siRNA Aortic_valve Valvular endothelial cell 2.18108 1.12504 1.626995e-01 5.947254e-01 DataSet_03_456
HMOX1 SREBF2 siRNA Umbilical_vein HUVEC 0.597872 -0.742092 5.536468e-05 9.027034e-03 DataSet_03_457
HMOX1 PARP1 knockout Embryo_kidney HEK293a 5.13016 2.359 3.079506e-13 7.384223e-11 DataSet_03_464
HMOX1 SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 2.72335 1.44538 - - DataSet_03_467
HMOX1 WHSC1 siRNA Prostate PC3 0.506761 -0.980623 2.213489e-03 0.07761533 DataSet_03_471
HMOX1 EZH2 siRNA Prostate LNCaP 0.453077 -1.14217 - - DataSet_03_472
HMOX1 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 0.571429 -0.807355 0.742584 0.9527008 DataSet_04_072
HMOX1 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 3.5 1.80736 0.6399616 0.777639792 DataSet_04_074
Regulation Region
 
T(co)Fs that significantly regulate SOX2 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of HMOX1
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines