Gene Overview
Target Gene: PBX1
NCBI Official Symbol: PBX1
Entrez ID: 5087
Ensembl ID: ENSG00000185630
Gene Full Name: PBX homeobox 1
Strand: +
Gene Locus: 1q23.3
External Links:

PBX1 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate PBX1   
T(co)Fs that Repress PBX1
The Intensity of the Gene Regulated by T(co)Fs:
PBX1-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
PBX1 IRF6 shRNA Fetal_liver Primary CD34+ hematopoietic stem/progenitor cells (HSPCs) 1.60707 0.68443 0.00147 0.02393 DataSet_01_101
PBX1 MYB shRNA Fetal_liver Primary CD34+ hematopoietic stem/progenitor cells (HSPCs) 1.73925 0.79846 7.54328e-06 6.20066e-05 DataSet_01_102
PBX1 SPDEF shRNA Mammary_gland MCF7 0.64005 -0.64375 0.90391 0.99999 DataSet_01_107
PBX1 GABPA siRNA Lung A549 1.5785 0.65856 2.657e-08 7.69511e-07 DataSet_01_113
PBX1 TCF3 shRNA Mammary_gland MDA-MB468 0.59998 -0.73702 0.00258 0.02311 DataSet_01_116
PBX1 ID1 siRNA Lung H1650 1.52307 0.60698 0.05619 0.37915 DataSet_01_118
PBX1 ZIC2 siRNA Pancreas PANC1 1.53333 0.61667 - - DataSet_01_121
PBX1 FOXM1 siRNA Central_nervous_system U87 0.14154 -2.82073 - - DataSet_01_122
PBX1 ID1 shRNA Neuroepithelium GSC8 1.6268 0.70204 3.23652e-09 1.09515e-08 DataSet_01_134
PBX1 IKZF2 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 1.57409 0.65452 0.21306 0.99993 DataSet_01_137
PBX1 IKZF1 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 2.54039 1.34505 0.0254 0.99993 DataSet_01_138
PBX1 TEAD4 shRNA Stomach SNU216 0.66005 -0.59934 - - DataSet_01_151
PBX1 LIN28B siRNA Embryo_kidney HEK293 0.64324 -0.63658 0.00135 0.02089 DataSet_01_153
PBX1 HSF1 shRNA Skin A375 0.41315 -1.27527 3.36804e-05 0.00101 DataSet_01_155
PBX1 JUN siRNA Peripheral_blood CD4+ T cells 0.53742 -0.89587 0.00299 0.03162 DataSet_01_164
PBX1 TP63 shRNA Bladder UC14 1.58708 0.66637 0.00052 0.00521 DataSet_01_183
PBX1 TCF4 siRNA Autonomic_ganglia SH-SY5Y 0.53495 -0.90254 2.34151e-05 0.0053 DataSet_01_185
PBX1 CREB1 shRNA Parotid_gland HSY 0.55704 -0.84415 0.00201 0.28796 DataSet_01_195
PBX1 TP63 siRNA Head_and_neck SCC-012 2.42319 1.27691 - - DataSet_01_201
PBX1 TP63 siRNA Head_and_neck SCC-6 1.67927 0.74783 - - DataSet_01_202
PBX1 XBP1 shRNA Mammary_gland T47D 0.33502 -1.5777 1.18601e-06 0.00017 DataSet_01_203
PBX1 HIC1 shRNA Mammary_gland HBL100 0.60368 -0.72814 - - DataSet_01_205
PBX1 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly10 0.63263 -0.66056 - - DataSet_01_208
PBX1 LIN28A siRNA Embryo H9 0.60045 -0.73588 0.00635 0.03775 DataSet_01_215
PBX1 IRX1 shRNA Bone_marrow 143B 0.66209 -0.59491 0.33973 0.59284 DataSet_01_227
PBX1 GATA6 siRNA Colon HT29 1.52792 0.61157 - - DataSet_01_247
PBX1 SMAD2 siRNA Liver Hep3B 1.50734 0.59201 - - DataSet_01_248
PBX1 SMAD3 siRNA Liver Hep3B 1.53321 0.61656 - - DataSet_01_249
PBX1 TWIST1 shRNA Stomach CAF32 2.37006 1.24492 0.00129 0.02126 DataSet_01_253
PBX1 TWIST1 shRNA Stomach CAF 1.57952 0.65949 0.09305 0.58485 DataSet_01_254
PBX1 SIX4 siRNA Ovary PEO1 2.71719 1.44212 0.00035 0.00747 DataSet_01_269
PBX1 TFAP4 siRNA Brain BE(2)-C 0.42247 -1.24309 0.52203 0.54602 DataSet_01_295
PBX1 ARID1B shRNA Liver IRM90 1.57548 0.65579 3.2746e-06 0.00045 DataSet_01_298
PBX1 PTEN shRNA Skin A431 5.93103 2.56828 0.00011 0.0655 DataSet_01_301
PBX1 NR2E1 shRNA Neuroepithelium PBT003 1.73566 0.79548 0.01096 0.43284 DataSet_01_306
PBX1 ARNT siRNA Upper_aerodigestive_tract HSC3 1.57233 0.65291 - - DataSet_01_315
PBX1 ELK3 shRNA Mammary_gland MDA-MB-231 3.96224 1.98632 2.22602e-06 5.22037e-05 DataSet_01_318
PBX1 MYC siRNA Colon HCT116 2.17562 1.12143 2.21185e-08 3.78098e-07 DataSet_01_324
PBX1 TP63 shRNA Immortalized_keratinocyte HaCaT 0.55858 -0.84016 9.67316e-08 7.29616e-06 DataSet_01_325
PBX1 TP63 shRNA Immortalized_keratinocyte HaCaT 0.55858 -0.84016 9.67316e-08 7.29616e-06 DataSet_01_328
PBX1 REST siRNA Skin NHEK 1.99058 0.99319 3.24512e-05 0.00586 DataSet_01_337
PBX1 GTF2B siRNA Cervix HeLa 2.49967 1.32174 - - DataSet_01_362
PBX1 RBM17 shRNA Liver HepG2 3.125 1.64386 0.34744 0.60897 DataSet_02_100
PBX1 SAFB2 shRNA Liver HepG2 0.37931 -1.39855 0.60816 0.69142 DataSet_02_102
PBX1 FIP1L1 shRNA Liver HepG2 1.83333 0.87447 0.73166 0.79762 DataSet_02_103
PBX1 HDGF shRNA Liver HepG2 2.125 1.08746 0.01319 0.10005 DataSet_02_104
PBX1 TAF15 shRNA Liver HepG2 18 4.16993 0.00305 0.01635 DataSet_02_106
PBX1 SSB shRNA Liver HepG2 0.3 -1.73697 0.01958 0.04269 DataSet_02_107
PBX1 ZNF622 shRNA Liver HepG2 0.2 -2.32193 0.30678 0.38554 DataSet_02_108
PBX1 HNRNPUL1 shRNA Liver HepG2 2.06897 1.04891 0.0519 0.10866 DataSet_02_109
PBX1 RBM39 shRNA Liver HepG2 10.5 3.39232 0.02313 0.21556 DataSet_02_111
PBX1 BCLAF1 shRNA Liver HepG2 1.625 0.70044 0.29347 0.41446 DataSet_02_112
PBX1 XRCC5 shRNA Liver HepG2 1.52381 0.60768 0.1244 0.3086 DataSet_02_114
PBX1 PCBP1 shRNA Liver HepG2 19 4.24793 0.11064 0.16973 DataSet_02_115
PBX1 SUB1 shRNA Liver HepG2 0.28571 -1.80735 0.0218 0.15851 DataSet_02_117
PBX1 CEBPZ shRNA Liver HepG2 3.33333 1.73697 0.1125 1 DataSet_02_118
PBX1 RBM25 shRNA Liver HepG2 35 5.12928 0.04228 0.09412 DataSet_02_119
PBX1 PTBP1 shRNA Liver HepG2 70 6.12928 0.01758 0.0342 DataSet_02_120
PBX1 RBM34 shRNA Liver HepG2 0.61905 -0.69188 0.33611 0.65993 DataSet_02_121
PBX1 FUS shRNA Liver HepG2 1.90476 0.92961 0.0363 0.14995 DataSet_02_124
PBX1 HNRNPLL shRNA Liver HepG2 0.3125 -1.67807 0.55671 0.63192 DataSet_02_125
PBX1 SNRNP70 shRNA Liver HepG2 0.3125 -1.67807 0.17196 0.27752 DataSet_02_126
PBX1 SRSF3 shRNA Liver HepG2 2.0625 1.04439 0.10386 0.23659 DataSet_02_127
PBX1 PRPF4 shRNA Liver HepG2 0.54545 -0.87447 0.02685 0.089 DataSet_02_128
PBX1 POLR2G shRNA Haematopoietic_and_lymphoid_tissue K562 0.55769 -0.84246 0.86443 0.97362 DataSet_02_130
PBX1 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.53704 -0.89691 0.32556 0.43655 DataSet_02_131
PBX1 SRSF7 shRNA Haematopoietic_and_lymphoid_tissue K562 2.07407 1.05247 0.07765 0.30789 DataSet_02_133
PBX1 PCBP2 shRNA Haematopoietic_and_lymphoid_tissue K562 2 1 0.3431 0.50325 DataSet_02_135
PBX1 RBM17 shRNA Haematopoietic_and_lymphoid_tissue K562 2.4 1.26303 0.1068 0.38158 DataSet_02_138
PBX1 RBFOX2 shRNA Haematopoietic_and_lymphoid_tissue K562 2.2 1.1375 0.4688 0.72548 DataSet_02_139
PBX1 RBM34 shRNA Haematopoietic_and_lymphoid_tissue K562 0.37037 -1.43296 0.08636 0.2909 DataSet_02_141
PBX1 BCLAF1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.79221 0.84174 0.06158 0.19734 DataSet_02_142
PBX1 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.24324 1.16559 0.00555 0.19727 DataSet_02_144
PBX1 FIP1L1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.34286 1.22827 0.00571 0.08524 DataSet_02_147
PBX1 ILF3 shRNA Haematopoietic_and_lymphoid_tissue K562 3.8 1.926 0.06767 0.33966 DataSet_02_148
PBX1 NONO shRNA Haematopoietic_and_lymphoid_tissue K562 1.96296 0.97303 0.4958 0.67089 DataSet_02_149
PBX1 SAFB2 shRNA Haematopoietic_and_lymphoid_tissue K562 1.7 0.76553 0.15917 0.59916 DataSet_02_150
PBX1 RBM39 shRNA Haematopoietic_and_lymphoid_tissue K562 0.62651 -0.6746 0.10952 0.31158 DataSet_02_151
PBX1 ILF2 shRNA Haematopoietic_and_lymphoid_tissue K562 5.56667 2.47681 0.0013 0.23369 DataSet_02_152
PBX1 YBX3 shRNA Haematopoietic_and_lymphoid_tissue K562 4.02857 2.01027 0.0188 0.41744 DataSet_02_153
PBX1 SRSF4 shRNA Haematopoietic_and_lymphoid_tissue K562 0.61538 -0.70044 0.31461 0.5961 DataSet_02_154
PBX1 HNRNPUL1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.46988 -1.08964 0.0741 0.51515 DataSet_02_156
PBX1 PSIP1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.25714 1.1745 0.09854 0.20737 DataSet_02_158
PBX1 SSB shRNA Haematopoietic_and_lymphoid_tissue K562 2.21154 1.14505 0.45186 0.64371 DataSet_02_164
PBX1 RBM25 shRNA Haematopoietic_and_lymphoid_tissue K562 0.32468 -1.62293 0.08548 0.28576 DataSet_02_166
PBX1 RBM22 shRNA Haematopoietic_and_lymphoid_tissue K562 2.2963 1.19931 0.05866 0.1507 DataSet_02_168
PBX1 TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 1.55556 0.63743 0.39803 0.50492 DataSet_02_169
PBX1 U2AF2 shRNA Haematopoietic_and_lymphoid_tissue K562 1.93506 0.95238 0.43021 0.55668 DataSet_02_170
PBX1 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.57143 -0.80735 0.00759 0.20622 DataSet_02_171
PBX1 NFE2L2 siRNA Haematopoietic_and_lymphoid_tissue K562 1.84906 0.88679 0.19792 1 DataSet_02_174
PBX1 LMNA siRNA Haematopoietic_and_lymphoid_tissue K562 0.56923 -0.81291 0.25614 1 DataSet_02_175
PBX1 CEBPZ siRNA Haematopoietic_and_lymphoid_tissue K562 2.38298 1.25277 0.73428 1 DataSet_02_176
PBX1 CTCF siRNA Haematopoietic_and_lymphoid_tissue K562 0.40741 -1.29546 0.07881 1 DataSet_02_185
PBX1 CHD1 siRNA Haematopoietic_and_lymphoid_tissue K562 2.00909 1.00654 0.32951 1 DataSet_02_187
PBX1 RAD21 siRNA Haematopoietic_and_lymphoid_tissue K562 3.12346 1.64314 0.64659 1 DataSet_02_190
PBX1 LMNB2 siRNA Haematopoietic_and_lymphoid_tissue K562 0.52308 -0.9349 0.27546 1 DataSet_02_191
PBX1 MAX siRNA Haematopoietic_and_lymphoid_tissue K562 1.59574 0.67423 0.57232 1 DataSet_02_192
PBX1 ARID3A siRNA Haematopoietic_and_lymphoid_tissue K562 2.13869 1.09672 0.27892 1 DataSet_02_193
PBX1 TCP1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.64615 -0.63005 0.37632 1 DataSet_02_194
PBX1 CDAN1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.61702 0.69334 0.36764 1 DataSet_02_197
PBX1 ZNF384 siRNA Haematopoietic_and_lymphoid_tissue K562 2.35 1.23266 0.07521 1 DataSet_02_203
PBX1 RCOR1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.30159 -1.72935 0.02901 1 DataSet_02_204
PBX1 AR siRNA Prostate abl cells 1.73913 0.798366 0.0843428089128151 0.999852161656754 DataSet_03_004
PBX1 AR siRNA Prostate LNCaP 2.17521 1.12115 0.145921951234479 1 DataSet_03_005
PBX1 FOXA1 siRNA Mammary_gland MCF7 1.62303 0.69869 0.000162809139728888 0.00349535909266959 DataSet_03_080
PBX1 FOXA1 siRNA Mammary_gland MCF7 1.67062 0.74038 1.60211671297991e-11 1.37901598265002e-09 DataSet_03_081
PBX1 FOXA1 siRNA Mammary_gland MCF7 1.67062 0.74038 1.60211671297991e-11 1.37901598265002e-09 DataSet_03_082
PBX1 FOXO1 siRNA Skin primary human dermal lymphatic endothelial cells 2.69208 1.42872 - - DataSet_03_096
PBX1 GATA3 siRNA Mammary_gland MCF7 1.85417 0.890775 0.066915002541617 0.201829347855863 DataSet_03_103
PBX1 IRF4 siRNA Skin Cutaneous T cell lymphoma HuT-102 cells 0.542987 -0.881012 0.25352856707019 0.999948959532916 DataSet_03_134
PBX1 Klf4 siRNA Skin Primary neonatal keratinocytes 2.93854 1.5551 7.49714747550897e-05 0.00185796008308466 DataSet_03_147
PBX1 MITF siRNA Skin Ma-Mel-15 2.31633 1.21184 0.00477540136224858 0.140969848213578 DataSet_03_166
PBX1 MITF siRNA Skin Ma-Mel-15 1.72476 0.786393 0.0121867308605211 0.152579399376406 DataSet_03_167
PBX1 MTA2 siRNA Stomach SGC-7901 0.289384 -1.78894 - - DataSet_03_169
PBX1 MYB siRNA Cord_Blood CD34+ progenitor cells 1.91993 0.941054 - - DataSet_03_170
PBX1 PBX1 siRNA Mammary_gland MCF7 0.274449 -1.86539 6.6805245761574e-09 0.000231159511384198 DataSet_03_207
PBX1 PBX1 siRNA Mammary_gland LTED 0.424 -1.23786 0.00012385570493317 0.644454904907285 DataSet_03_208
PBX1 PBX1 siRNA Mammary_gland MCF7 0.458874 -1.12383 1.05912023956482e-09 1.22158928431407e-05 DataSet_03_209
PBX1 PHB shRNA Embryo Embryonic stem cells (ESCs) 0.267948 -1.89997 1.33280483023217e-06 0.000163916384040523 DataSet_03_211
PBX1 SOX2 CRISPR Seminoma-like TCam-2 0.461023 -1.11709 0.0659063793677117 0.999580851453413 DataSet_03_244
PBX1 SP1 siRNA Cervix HeLa 0.653577 -0.61357 0.000113269858756249 0.0020001405659526 DataSet_03_249
PBX1 SP1 siRNA Ovary OVSAYO 4.2666 2.09309 0.00105376454229331 0.0671315998250021 DataSet_03_251
PBX1 STAT3 CRISPR Embryo hESC 3.378 1.75617 0.00176572244839422 0.0309520758600869 DataSet_03_258
PBX1 TP53 knockout Haematopoietic_and_lymphoid_tissue MOLP8 0.643506 -0.635974 0.0296360072199521 0.658232370081292 DataSet_03_280
PBX1 TP63 siRNA Skin Primary neonatal keratinocytes 2.00441 1.00318 0.000131045504234929 0.00332293957167142 DataSet_03_281
PBX1 ZNF750 siRNA Skin Primary neonatal keratinocytes 2.46327 1.30058 0.00134163752520381 0.0343644654049992 DataSet_03_294
PBX1 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 2.59322 1.37475 0.0406062533446463 0.116080156937527 DataSet_04_002
PBX1 CIZ1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.45946 -1.12199 0.0549347335815523 0.115301655983969 DataSet_04_004
PBX1 E4F1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.601942 -0.732304 0.040166533255705 0.46816156992682 DataSet_04_007
PBX1 FUBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 4.14706 2.05209 0.0750634293699989 0.167770550261584 DataSet_04_010
PBX1 FUBP3 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.54762 0.63005 0.00410975403612074 0.54561094583539 DataSet_04_011
PBX1 MARK2 shRNA Haematopoietic_and_lymphoid_tissue K562 1.91919 0.940499 0.00808476568552825 0.0262802219473377 DataSet_04_012
PBX1 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 2.00833 1.006 0.917004906504702 0.947132676625561 DataSet_04_014
PBX1 NUP35 shRNA Haematopoietic_and_lymphoid_tissue K562 0.454545 -1.1375 0.0138534329193679 0.0394360425824978 DataSet_04_015
PBX1 SMAD2 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.74306 0.801619 0.16949036673107 0.309593477013127 DataSet_04_018
PBX1 YBX1 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.72571 0.787194 0.0166775688163703 0.450425584370459 DataSet_04_022
PBX1 CTCF CRISPR Liver HepG2 2.25 1.16992 0.61656598105102 0.943593124097821 DataSet_04_027
PBX1 ERN1 CRISPR Liver HepG2 0.214286 -2.22239 0.0453466383541533 0.181740264395216 DataSet_04_029
PBX1 FUBP1 shRNA Liver HepG2 0.642857 -0.63743 0.446788705237938 0.734167819442101 DataSet_04_030
PBX1 MECP2 CRISPR Liver HepG2 0.357143 -1.48543 0.0982015054981415 0.361055313241796 DataSet_04_031
PBX1 NFX1 CRISPR Liver HepG2 0.0847458 -3.56071 0.0007879022783451 0.0127039521932353 DataSet_04_032
PBX1 SMAD4 CRISPR Liver HepG2 2.21429 1.14684 0.0452651184701236 0.159750626038568 DataSet_04_035
PBX1 SRPK2 CRISPR Liver HepG2 0.285714 -1.80736 0.0518739097717817 0.204984230026571 DataSet_04_037
PBX1 APTX CRISPR Liver HepG2 2.25 1.16992 0.642839695000929 0.969646467319838 DataSet_04_069
PBX1 CHCHD3 CRISPR Liver HepG2 0.416667 -1.26303 0.603636501061204 0.840809986526392 DataSet_04_067
PBX1 CNOT7 CRISPR Liver HepG2 0.411765 -1.28011 0.245945039637947 0.404131548707472 DataSet_04_045
PBX1 DNMT3B CRISPR Liver HepG2 0.294118 -1.76553 0.21468378559872 0.480537779974623 DataSet_04_044
PBX1 PAN2 CRISPR Liver HepG2 2.21429 1.14684 0.126607549445329 0.267597228469506 DataSet_04_066
PBX1 SEPT11 CRISPR Liver HepG2 18 4.16993 0.199973643490531 0.453311013371605 DataSet_04_068
PBX1 ABT1 shRNA Liver HepG2 0.59322 -0.75336 0.353644201057758 0.484791207046925 DataSet_04_052
PBX1 CCAR1 shRNA Liver HepG2 4.14286 2.05063 0.0223246800863365 0.0773372289365005 DataSet_04_054
PBX1 CNOT7 shRNA Liver HepG2 0.342857 -1.54432 0.218993514587187 0.313807430971185 DataSet_04_051
PBX1 YBX3 shRNA Liver HepG2 0.25 -2 0.170008197144061 0.344458865072466 DataSet_02_98
PBX1 ACTN4 CRISPR Haematopoietic_and_lymphoid_tissue K562 3.78125 1.91886 0.0177590541979169 0.0991133426932383 DataSet_04_048
PBX1 DDX20 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.90476 0.929611 0.00656676811607922 0.326642577842938 DataSet_04_050
PBX1 SNW1 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.69412 1.42981 0.00672814533275396 0.0351303266368054 DataSet_04_049
PBX1 CITED2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.58914 0.668243 0.0341301778897376 0.187276930742978 DataSet_02_38
PBX1 DPF2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.369081 -1.43799 0.00050503152884131 0.00824220294785054 DataSet_02_14
PBX1 ERF CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.373259 -1.42175 0.000588260499155694 0.0132168966764494 DataSet_02_34
PBX1 HMGA1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.93143 0.949668 0.00312836963206407 0.393478982766751 DataSet_02_75
PBX1 SNW1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.532738 -0.908502 0.0725610597276231 0.460265056026108 DataSet_02_49
PBX1 TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.639276 -0.64549 0.0602946764303401 0.130957558540139 DataSet_02_33
PBX1 ABT1 shRNA Haematopoietic_and_lymphoid_tissue K562 6.13235 2.61644 0.000222809862266316 0.0148125294356175 DataSet_04_060
PBX1 CCAR1 shRNA Haematopoietic_and_lymphoid_tissue K562 4.57143 2.19265 0.0102714825377122 0.0686046875086219 DataSet_04_064
PBX1 CNOT7 shRNA Haematopoietic_and_lymphoid_tissue K562 15.6333 3.96655 0.000688469856589951 0.0395443736754959 DataSet_04_061
PBX1 DDX1 shRNA Haematopoietic_and_lymphoid_tissue K562 3.82857 1.93681 0.0365860692579139 0.480673755367965 DataSet_04_063
PBX1 PRPF6 shRNA Haematopoietic_and_lymphoid_tissue K562 1.84615 0.884523 0.110666533108066 0.468683195050504 DataSet_04_065
PBX1 PATZ1 siRNA Liver HepG2 2.17873 1.12349 4.166919e-07 5.522144e-04 DataSet_03_296
PBX1 PATZ1 siRNA Liver HepG2 2.17873 1.12349 4.166919e-07 5.522144e-04 DataSet_03_297
PBX1 ELF3 knockdown Bile_duct HBDEC2 1.5352 0.61843 1.224828e-03 2.241215e-02 DataSet_03_305
PBX1 SNAI2 shRNA Pancreas KLM1 0.362158 -1.46531 8.907738e-03 0.16121838 DataSet_03_307
PBX1 PBX1 siRNA Mammary_gland MCF7 0.458874 -1.12383 1.462558e-09 1.527593e-05 DataSet_03_326
PBX1 ARID3B CRISPR Colon HCT15 0.475887 -1.07131 - - DataSet_03_335
PBX1 TET1 CRISPR Mammary_gland MDA-MB-231 0.208106 -2.26461 4.479773e-04 7.563574e-03 DataSet_03_347
PBX1 TET1 CRISPR Mammary_gland Hs578T 0.535546 -0.900918 4.645612e-02 1.375492e-01 DataSet_03_355
PBX1 MYC siRNA Peripheral_blood T lymphocyte 8.89406 3.15284 7.062439e-01 0.860300159 DataSet_03_363
PBX1 EP300 shRNA Mammary_gland MCF10AT 4.17647 2.06228 2.671367e-03 0.034488637 DataSet_03_364
PBX1 ZNF148 shRNA Mammary_gland MDA-MB-231 0.419708 -1.25254 2.893710e-02 0.127582349 DataSet_03_366
PBX1 USP22 shRNA Liver PLC_PRF_5 cells 2.06667 1.04731 1.074069e-02 0.12194554 DataSet_03_368
PBX1 DNMT3A knockout Embryo_kidney HEK293T 0.184698 -2.43676 - - DataSet_03_369
PBX1 ZFP36L1 siRNA Urinary_bladder J82 3.22314 1.68847 - - DataSet_03_371
PBX1 BHLHE40 shRNA Cervix HeLaS3 0.657808 -0.604261 1.618854e-01 0.84447131 DataSet_03_372
PBX1 HNRNPU siRNA Colon RKO 0.307267 -1.70243 - - DataSet_03_374
PBX1 NFKB2 siRNA Bone_marrow U2OS 0.191223 -2.38668 4.019840e-03 0.09402394 DataSet_03_381
PBX1 KAT6A CRISPR Haematopoietic_and_lymphoid_tissue MOLM-13 1.97719 0.983453 0.8504176218 0.9754239 DataSet_03_387
PBX1 TRIM8 siRNA Mammary_gland MCF7 0.474099 -1.07674 4.515348e-06 0.0012728436 DataSet_03_388
PBX1 NFKBIA shRNA Bone_marrow U2OS 0.474339 -1.07601 4.724205e-01 0.87005461 DataSet_03_389
PBX1 YY1 knockdown Liver HepG2 1.75 0.807355 4.196993e-01 5.965989e-01 DataSet_03_390
PBX1 ILF2 siRNA Stomach SGC-7901 2.26667 1.18057 0.0192235971 0.07685873 DataSet_03_393
PBX1 IKZF2 CRISPR Lymph CAR T Cell 0.627069 -0.673304 2.686479e-01 0.753482753 DataSet_03_397
PBX1 TLE4 CRISPR Lymph CAR T Cell 0.361658 -1.4673 2.010126e-02 0.16867570 DataSet_03_398
PBX1 RELA CRISPR Brain T30 0.353024 -1.50216 0.1614717178 0.8400824 DataSet_03_399
PBX1 CDK7 shRNA Bone_marrow D458 0.50314 -0.990969 1.804011e-02 0.21276725 DataSet_03_404
PBX1 USP22 shRNA Liver HuH7 2.96147 1.56631 - - DataSet_03_411
PBX1 ZKSCAN3 CRISPR Colon HCT116 0.332159 -1.59006 3.804580e-02 0.383238191 DataSet_03_415
PBX1 RUNX2 shRNA Cord_blood Natural Killer Cell 0.111111 -3.16992 4.767062e-01 0.803311702 DataSet_03_416
PBX1 NFATC2 shRNA Haematopoietic_and_lymphoid_tissue THP-1 0.25 -2 3.878934e-01 0.596227590 DataSet_03_418
PBX1 FOXK2 shRNA Ovary OVCAR-5 0.260702 -1.93953 4.042449e-02 0.16078314 DataSet_03_419
PBX1 BRD4 CRISPR Lymph CD8+ T cells 3 1.58496 - - DataSet_03_420
PBX1 FOXQ1 CRISPR Lymph Primary CD4+ T cells 0.610294 -0.712423 - - DataSet_03_422
PBX1 MAEL CRISPR Liver Alexander cells 1.80027 0.848212 - - DataSet_03_423
PBX1 FOXP3 CRISPR Peripheral_blood Naive Treg 0.0590164 -4.08274 3.132678e-01 0.649908366 DataSet_03_427
PBX1 USP7 shRNA Skin xenograft cells 0.525445 -0.928388 0.35670015 0.4901191 DataSet_03_431
PBX1 PLAG1 shRNA Cord_blood Lin-CD34+ HSPCs 0.196109 -2.35027 - - DataSet_03_432
PBX1 POU2AF1 CRISPR Haematopoietic_and_lymphoid_tissue OCI-Ly7 2.57143 1.36257 2.927772e-01 0.574894029 DataSet_03_434
PBX1 POU2AF1 CRISPR Lymph SUDHL4 0.25 -2 2.631870e-01 0.445514196 DataSet_03_435
PBX1 FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 0.515936 -0.954737 1.732983e-01 0.90558273 DataSet_03_439
PBX1 SETDB1 shRNA Colon HCT116 0.584994 -0.773506 - - DataSet_03_440
PBX1 DAXX shRNA Mammary_gland MDA-MB-231 0.33688 -1.56969 4.678840e-03 0.08361834 DataSet_03_441
PBX1 PHF14 siRNA Mammary_gland MDA-MB-231 1.8153 0.860211 0.0268567684 0.3650662 DataSet_03_443
PBX1 RELB CRISPR Colon SW480 4.25 2.08746 2.964005e-04 1.201413e-02 DataSet_03_449
PBX1 CBX2 siRNA Mammary_gland MDA-MB-231 0.475285 -1.07313 9.294378e-03 4.449039e-02 DataSet_03_450
PBX1 CBX2 siRNA Mammary_gland MCF7 0.4921 -1.02298 2.021069e-05 0.0006532269 DataSet_03_451
PBX1 ARID1A shRNA Bile_duct MMNK1 0.423047 -1.24111 4.419154e-03 0.063545883 DataSet_03_458
PBX1 TXNIP shRNA Cord_Blood CD34+ cells 2.05877 1.04178 - - DataSet_03_461
PBX1 TXNIP shRNA Cord_blood ST3 2.31802 1.21289 5.116954e-03 0.1163095392 DataSet_03_462
PBX1 STAT3 shRNA Liver HepG2 1.51928 0.60339 8.196219e-02 0.3967514505 DataSet_03_465
PBX1 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 2.59322 1.37475 0.01105908 0.045848247 DataSet_04_074
Regulation Region
 
T(co)Fs that significantly regulate PBX1 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of PBX1
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines