Gene Overview
Target Gene: COL5A1
NCBI Official Symbol: COL5A1
Entrez ID: 1289
Ensembl ID: ENSG00000130635
Gene Full Name: collagen type V alpha 1 chain
Strand: +
Gene Locus: 9q34.3
External Links:

COL5A1 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate COL5A1   
T(co)Fs that Repress COL5A1
The Intensity of the Gene Regulated by T(co)Fs:
COL5A1-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
COL5A1 SPDEF shRNA Mammary_gland MCF7 0.17995 -2.47436 0.54011 0.99999 DataSet_01_107
COL5A1 GABPA siRNA Lung A549 2.01171 1.00842 2.30388e-09 1.29603e-07 DataSet_01_113
COL5A1 ID1 siRNA Lung A549 3.32758 1.73447 0.00075 0.08908 DataSet_01_117
COL5A1 ZIC2 siRNA Pancreas PANC1 1.54563 0.6282 - - DataSet_01_121
COL5A1 FOXM1 siRNA Central_nervous_system U87 5.1342 2.36014 - - DataSet_01_122
COL5A1 ZNF254 siRNA Gastrointestinal_tissue GIST-T1 1.66057 0.73168 0.00011 0.0033 DataSet_01_127
COL5A1 ZNF431 siRNA Gastrointestinal_tissue GIST-T1 1.74404 0.80243 5.21229e-05 0.00131 DataSet_01_128
COL5A1 NFYA shRNA Cervix HeLaS3 1.89317 0.9208 7.09441e-06 0.00106 DataSet_01_131
COL5A1 ID1 shRNA Neuroepithelium GSC2 2.32841 1.21935 4.22571e-12 1.67779e-10 DataSet_01_133
COL5A1 ID1 shRNA Neuroepithelium GSC8 3.35871 1.74791 2.57363e-13 1.01187e-11 DataSet_01_134
COL5A1 SPDEF shRNA Mammary_gland MCF7 2.5537 1.35259 3.62342e-06 0.00488 DataSet_01_135
COL5A1 SOX4 shRNA Parotid_gland ACC3 1.58175 0.66152 0.29868 0.98034 DataSet_01_140
COL5A1 SF1 siRNA Adrenal_gland H295R/TR 1.58485 0.66434 8.37225e-05 0.00227 DataSet_01_146
COL5A1 LIN28B siRNA Embryo_kidney HEK293 0.52752 -0.92271 0.001 0.01869 DataSet_01_153
COL5A1 HSF1 shRNA Skin A375 2.52732 1.33761 4.43245e-06 0.00023 DataSet_01_155
COL5A1 ESRRG siRNA Placenta_tissue Trophoblast cells 2.36545 1.24211 0.11064 0.478 DataSet_01_173
COL5A1 STAT3 siRNA Urothelial Scaber 0.59758 -0.74279 0.00066 0.00913 DataSet_01_184
COL5A1 TCF4 siRNA Autonomic_ganglia SH-SY5Y 1.86263 0.89734 0.00117 0.03244 DataSet_01_185
COL5A1 GATA2 siRNA Prostate LNCaP 2.83301 1.50233 0.00102 0.00594 DataSet_01_193
COL5A1 CREB1 shRNA Parotid_gland H3118 MEC 2.23485 1.16018 0.00851 0.17343 DataSet_01_194
COL5A1 TP63 siRNA Immortalized_keratinocyte HaCaT RG 1.69912 0.76479 - - DataSet_01_196
COL5A1 TP63 siRNA Immortalized_keratinocyte HaCaT 2.75822 1.46374 - - DataSet_01_200
COL5A1 TP63 siRNA Head_and_neck SCC-012 2.07143 1.05063 - - DataSet_01_201
COL5A1 TP63 siRNA Head_and_neck SCC-6 5.22334 2.38497 - - DataSet_01_202
COL5A1 LIN28A siRNA Embryo H9 1.59181 0.67067 0.03661 0.11225 DataSet_01_215
COL5A1 ESR2 siRNA Mammary_gland BT549 1.56193 0.64333 1.47631e-06 8.00439e-05 DataSet_01_229
COL5A1 TWIST1 shRNA Stomach CAF32 0.46733 -1.09748 0.00063 0.01701 DataSet_01_253
COL5A1 TWIST1 shRNA Stomach CAF 0.61597 -0.69907 0.01733 0.52717 DataSet_01_254
COL5A1 YBX1 shRNA Mammary_gland MDA 0.4228 -1.24194 5.99914e-06 0.00035 DataSet_01_257
COL5A1 SIX4 siRNA Ovary PEO1 1.59136 0.67026 0.01933 0.10512 DataSet_01_269
COL5A1 FOXO1 siRNA Umbilical_vein HUVEC 1.58931 0.6684 0.00494 0.0447 DataSet_01_270
COL5A1 MSX1 siRNA Tooth Dental Pulp Cells 0.61094 -0.7109 5.29831e-05 0.00068 DataSet_01_281
COL5A1 ZIC5 siRNA Skin A375 0.27736 -1.85017 - - DataSet_01_284
COL5A1 POSTN shRNA Brain GSC272 2.29247 1.1969 0.08681 0.54319 DataSet_01_293
COL5A1 RELB siRNA Lung A549 1.77286 0.82608 0.10428 0.3843 DataSet_01_294
COL5A1 TFAP4 siRNA Brain BE(2)-C 0.04691 -4.41392 0.11842 0.51625 DataSet_01_295
COL5A1 PTEN shRNA Mammary_gland SKBR3 0.65565 -0.609 0.39547 0.77603 DataSet_01_303
COL5A1 ELK3 shRNA Mammary_gland MDA-MB-231 2.09944 1.07 0.00045 0.00184 DataSet_01_318
COL5A1 MYC siRNA Colon HCT116 2.27543 1.18614 0.00012 0.00052 DataSet_01_324
COL5A1 STAT3 siRNA Liver LX-2 1.79089 0.84068 7.00584e-10 1.35078e-07 DataSet_01_334
COL5A1 NFE2L2 siRNA Lung A549 4.4354 2.14907 2.13544e-10 2.21184e-07 DataSet_01_335
COL5A1 REST siRNA Skin NHEK 1.79095 0.84073 0.00018 0.01405 DataSet_01_337
COL5A1 PAX3 shRNA Soft_tissue Rh30 0.59003 -0.76115 - - DataSet_01_359
COL5A1 SOX17 siRNA Umbilical_vein HUVEC 2.69498 1.43027 - - DataSet_01_360
COL5A1 RBFOX2 shRNA Liver HepG2 3 1.58496 0.25437 0.68668 DataSet_02_101
COL5A1 SAFB2 shRNA Liver HepG2 0.04167 -4.58496 0.03716 0.08694 DataSet_02_102
COL5A1 FIP1L1 shRNA Liver HepG2 2.5 1.32193 0.19317 0.28874 DataSet_02_103
COL5A1 HDGF shRNA Liver HepG2 0.25 -2 0.29274 0.47506 DataSet_02_104
COL5A1 SSB shRNA Liver HepG2 0.125 -3 0.00709 0.02139 DataSet_02_107
COL5A1 HNRNPUL1 shRNA Liver HepG2 0.25 -2 0.05118 0.10774 DataSet_02_109
COL5A1 GTF2F1 shRNA Liver HepG2 0.28571 -1.80735 0.54183 0.79195 DataSet_02_110
COL5A1 BCLAF1 shRNA Liver HepG2 0.13333 -2.90689 0.45657 0.57298 DataSet_02_112
COL5A1 XRCC5 shRNA Liver HepG2 0.21429 -2.22239 0.90705 0.95283 DataSet_02_114
COL5A1 TARDBP shRNA Liver HepG2 0.15 -2.73697 0.09666 0.16531 DataSet_02_116
COL5A1 SUB1 shRNA Liver HepG2 0.07143 -3.80735 0.43798 0.61559 DataSet_02_117
COL5A1 CEBPZ shRNA Liver HepG2 0.4 -1.32193 0.02371 1 DataSet_02_118
COL5A1 EWSR1 shRNA Liver HepG2 0.1875 -2.41504 0.19154 0.31178 DataSet_02_122
COL5A1 PCBP2 shRNA Liver HepG2 0.21429 -2.22239 0.43092 0.59875 DataSet_02_123
COL5A1 FUS shRNA Liver HepG2 0.14286 -2.80735 0.2826 0.47245 DataSet_02_124
COL5A1 SNRNP70 shRNA Liver HepG2 0.025 -5.32193 0.08813 0.17479 DataSet_02_126
COL5A1 SRSF3 shRNA Liver HepG2 0.2 -2.32193 0.1521 0.29878 DataSet_02_127
COL5A1 PRPF4 shRNA Liver HepG2 0.05263 -4.24793 0.10678 0.20657 DataSet_02_128
COL5A1 TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 2.61538 1.38702 0.30264 0.58731 DataSet_02_129
COL5A1 SRSF7 shRNA Haematopoietic_and_lymphoid_tissue K562 0.15385 -2.70044 0.00053 0.22541 DataSet_02_133
COL5A1 SRSF9 shRNA Haematopoietic_and_lymphoid_tissue K562 0.23077 -2.11548 0.03042 0.12824 DataSet_02_134
COL5A1 HNRNPK shRNA Haematopoietic_and_lymphoid_tissue K562 0.15385 -2.70044 0.00051 0.14272 DataSet_02_136
COL5A1 RBM17 shRNA Haematopoietic_and_lymphoid_tissue K562 13 3.70044 0.01008 0.25101 DataSet_02_138
COL5A1 RBM34 shRNA Haematopoietic_and_lymphoid_tissue K562 0.30769 -1.70044 0.00093 0.20864 DataSet_02_141
COL5A1 BCLAF1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.5 1.32193 0.01116 0.1117 DataSet_02_142
COL5A1 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.2 -2.32193 0.00233 0.02244 DataSet_02_143
COL5A1 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 3.66667 1.87447 0.02424 0.21117 DataSet_02_144
COL5A1 DROSHA shRNA Haematopoietic_and_lymphoid_tissue K562 8 3 0.01971 0.51061 DataSet_02_145
COL5A1 CCAR2 shRNA Haematopoietic_and_lymphoid_tissue K562 8 3 0.20649 0.6226 DataSet_02_146
COL5A1 FIP1L1 shRNA Haematopoietic_and_lymphoid_tissue K562 3 1.58496 0.4787 0.61613 DataSet_02_147
COL5A1 NONO shRNA Haematopoietic_and_lymphoid_tissue K562 0.05556 -4.16993 0.00034 0.19424 DataSet_02_149
COL5A1 SAFB2 shRNA Haematopoietic_and_lymphoid_tissue K562 9.33333 3.22239 0.21302 0.64464 DataSet_02_150
COL5A1 RBM39 shRNA Haematopoietic_and_lymphoid_tissue K562 12 3.58496 0.00734 0.23644 DataSet_02_151
COL5A1 SRSF4 shRNA Haematopoietic_and_lymphoid_tissue K562 5.66667 2.5025 0.09613 0.41402 DataSet_02_154
COL5A1 FUS shRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 1 1 DataSet_02_155
COL5A1 HNRNPUL1 shRNA Haematopoietic_and_lymphoid_tissue K562 17 4.08746 0.20392 0.55742 DataSet_02_156
COL5A1 PSIP1 shRNA Haematopoietic_and_lymphoid_tissue K562 6.5 2.70044 9.70997e-05 0.0795 DataSet_02_158
COL5A1 HNRNPL shRNA Haematopoietic_and_lymphoid_tissue K562 8 3 0.19773 0.37638 DataSet_02_160
COL5A1 SUB1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.33333 -1.58496 0.46961 0.89363 DataSet_02_161
COL5A1 RBM22 shRNA Haematopoietic_and_lymphoid_tissue K562 0.38462 -1.37851 0.139 0.25455 DataSet_02_168
COL5A1 U2AF2 shRNA Haematopoietic_and_lymphoid_tissue K562 8 3 0.00039 0.04371 DataSet_02_170
COL5A1 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 1 1 DataSet_02_171
COL5A1 MXI1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.54167 0.62449 0.70707 1 DataSet_02_173
COL5A1 LMNA siRNA Haematopoietic_and_lymphoid_tissue K562 0.30303 -1.72247 0.08339 1 DataSet_02_175
COL5A1 CEBPZ siRNA Haematopoietic_and_lymphoid_tissue K562 0.17073 -2.5502 0.05276 1 DataSet_02_176
COL5A1 ZNF180 siRNA Haematopoietic_and_lymphoid_tissue K562 0.41667 -1.26303 0.16917 1 DataSet_02_177
COL5A1 KAT2B siRNA Haematopoietic_and_lymphoid_tissue K562 0.375 -1.41504 0.13154 1 DataSet_02_184
COL5A1 BHLHE40 siRNA Haematopoietic_and_lymphoid_tissue K562 25 4.64386 0.40974 1 DataSet_02_186
COL5A1 MAFG siRNA Haematopoietic_and_lymphoid_tissue K562 1.7561 0.81237 0.99071 1 DataSet_02_189
COL5A1 LMNB2 siRNA Haematopoietic_and_lymphoid_tissue K562 2.06061 1.04307 0.63794 1 DataSet_02_191
COL5A1 ARID3A siRNA Haematopoietic_and_lymphoid_tissue K562 0.14706 -2.76553 0.47046 1 DataSet_02_193
COL5A1 LMNB1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.41463 -1.27009 0.30743 1 DataSet_02_195
COL5A1 UBTF siRNA Haematopoietic_and_lymphoid_tissue K562 19 4.24793 0.00057 1 DataSet_02_198
COL5A1 E2F4 siRNA Haematopoietic_and_lymphoid_tissue K562 0.27273 -1.87447 0.07011 1 DataSet_02_200
COL5A1 TAL1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.53846 0.62149 0.28011 1 DataSet_02_201
COL5A1 ZNF384 siRNA Haematopoietic_and_lymphoid_tissue K562 0.26923 -1.89308 0.06792 1 DataSet_02_203
COL5A1 RCOR1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.61765 0.6939 0.57728 1 DataSet_02_204
COL5A1 E2F6 siRNA Haematopoietic_and_lymphoid_tissue K562 0.65854 -0.60266 0.71039 1 DataSet_02_205
COL5A1 AR siRNA Prostate LNCaP 1.64008 0.713768 0.341993379872885 1 DataSet_03_005
COL5A1 FOXA1 siRNA Mammary_gland MCF7 7.82262 2.96765 4.1819385066042e-11 1.03634410391519e-07 DataSet_03_080
COL5A1 FOXA1 siRNA Mammary_gland MCF7 2.35809 1.23762 3.24576364306349e-13 4.9915517145459e-11 DataSet_03_081
COL5A1 FOXA1 siRNA Mammary_gland MCF7 2.35809 1.23762 3.24576364306349e-13 4.9915517145459e-11 DataSet_03_082
COL5A1 FOXO1 siRNA Skin primary human dermal lymphatic endothelial cells 2.25554 1.17348 - - DataSet_03_096
COL5A1 GATA2 siRNA Uterus Decidual stromal cells 0.608996 -0.715495 0.366457635152353 0.894167096037892 DataSet_03_100
COL5A1 GATA2 siRNA Lymph Lymphatic endothelial cells 1.50371 0.588528 0.00293043258337509 0.00881797162184063 DataSet_03_101
COL5A1 HMGA2 siRNA Mammary_gland MDA-MB-231 5.1526 2.3653 0.00122772840786655 0.329054469606356 DataSet_03_125
COL5A1 HNF4a siRNA Liver HepG2 2.76101 1.46519 0.0052377703168568 0.40653733409152 DataSet_03_126
COL5A1 JUN siRNA Mammary_gland MCF7 1.62895 0.703942 0.94877494016052 0.999857657786768 DataSet_03_142
COL5A1 KDM3A siRNA Mammary_gland MCF7 3.49712 1.80617 7.49053214924616e-07 0.000382171356449921 DataSet_03_146
COL5A1 Klf4 siRNA Skin Primary neonatal keratinocytes 2.98101 1.5758 0.000102822860588814 0.0022350303353512 DataSet_03_147
COL5A1 KLF5 siRNA Stomach YCC3 0.482193 -1.05232 0.180827015402694 0.548357275752493 DataSet_03_151
COL5A1 MCM2 siRNA Mammary_gland MCF7 1.50048 0.585421 0.0420474725302691 0.999925560383539 DataSet_03_161
COL5A1 MEF2D shRNA Liver HuH7 1.58075 0.660611 - - DataSet_03_162
COL5A1 MEF2D siRNA Liver HuH7 0.395698 -1.33753 - - DataSet_03_163
COL5A1 MITF siRNA Skin Ma-Mel-15 2.96885 1.5699 0.00041142001129818 0.0308885595495426 DataSet_03_166
COL5A1 MITF siRNA Skin Ma-Mel-15 2.68539 1.42513 3.13394739321966e-06 0.000478872684058225 DataSet_03_167
COL5A1 MYB siRNA Cord_Blood CD34+ progenitor cells 1.61902 0.69512 - - DataSet_03_170
COL5A1 MYC siRNA Central_nervous_system DAOY M2.1 3.95019 1.98192 1.1090138507371e-09 1.5131561439671e-07 DataSet_03_178
COL5A1 NFAT5 siRNA Synovial Primary fibroblast-like synoviocytes 0.658747 -0.602203 0.264622978574741 0.672293207534082 DataSet_03_194
COL5A1 PHB shRNA Embryo Embryonic stem cells (ESCs) 8.30216 3.05349 1.20576943242679e-06 0.000161586617354113 DataSet_03_211
COL5A1 SOX11 siRNA Lung_fibroblast NHLF 1.69222 0.75892 0.123955191408838 0.524080537423846 DataSet_03_237
COL5A1 SOX11 siRNA Lung_fibroblast NHLF 2.07854 1.05557 0.261102910680488 0.628263061527302 DataSet_03_238
COL5A1 SOX2 CRISPR Seminoma-like TCam-2 1.71411 0.777456 0.311717743939901 0.999580851453413 DataSet_03_244
COL5A1 SP1 siRNA Cervix HeLa 1.75281 0.809672 4.11329916299389e-05 0.00105981150384383 DataSet_03_249
COL5A1 STAT3 CRISPR Embryo hESC 0.549231 -0.864514 0.191579857828321 0.260914353040502 DataSet_03_258
COL5A1 TFAP2C siRNA Mammary_gland MCF7 0.445659 -1.16599 0.00766170082618547 0.250968522515396 DataSet_03_274
COL5A1 TFE3 siRNA Kidney UOK257-2 3.12957 1.64596 - - DataSet_03_275
COL5A1 TP53 siRNA Foreskin Neonatal foreskin keratinocytes 0.600649 -0.735407 0.0433084908361826 0.999791649573014 DataSet_03_278
COL5A1 TP63 siRNA Skin Primary neonatal keratinocytes 5.28493 2.40188 7.95568942298677e-07 0.000753655439130832 DataSet_03_281
COL5A1 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 0.435897 -1.19794 0.836616936679926 0.958977528108705 DataSet_04_001
COL5A1 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.446043364024487 0.56818567339715 DataSet_04_002
COL5A1 CIZ1 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.8 0.847997 0.16824856788799 0.260625943088825 DataSet_04_004
COL5A1 DDX59 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.61539 0.691878 0.069898130875749 0.529009626438517 DataSet_04_006
COL5A1 E4F1 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.55556 0.63743 0.149591226466581 0.586170015351558 DataSet_04_007
COL5A1 EIF2AK2 CRISPR Haematopoietic_and_lymphoid_tissue K562 6.6 2.72247 0.1361650656039 0.518024035569298 DataSet_04_008
COL5A1 ERN1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.555556 -0.847997 0.136670650110329 0.743594795320557 DataSet_04_009
COL5A1 MECP2 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.45 -1.152 0.657614683818648 0.94278028030641 DataSet_04_013
COL5A1 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 367.735 8.52252 0.0170494437063844 0.0691488033152363 DataSet_04_014
COL5A1 SMAD4 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.3 -1.73697 0.404798509206194 0.568483097034568 DataSet_04_019
COL5A1 SMAD5 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.55556 0.63743 0.342414516995244 0.657018236075143 DataSet_04_020
COL5A1 YBX1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.0918367 -3.44479 0.447270230945472 0.737114424643288 DataSet_04_022
COL5A1 ANXA2 CRISPR Liver HepG2 0.65 -0.621488 0.999999999999999 1 DataSet_04_024
COL5A1 FUBP1 shRNA Liver HepG2 0.25 -2 0.296413618349316 0.633744016565176 DataSet_04_030
COL5A1 MECP2 CRISPR Liver HepG2 0.5 -1 0.744144990247907 0.876805814432645 DataSet_04_031
COL5A1 NFX1 CRISPR Liver HepG2 0.289474 -1.7885 0.349002340128203 0.444040694598343 DataSet_04_032
COL5A1 SMAD2 CRISPR Liver HepG2 2 1 0.485911110268795 0.839322445272542 DataSet_04_034
COL5A1 SMAD4 CRISPR Liver HepG2 6.83333 2.77259 0.0117100344483978 0.0962949222479783 DataSet_04_035
COL5A1 ZC3H8 shRNA Liver HepG2 0.0789474 -3.66297 0.0697092515949021 0.219606923325117 DataSet_04_040
COL5A1 APTX CRISPR Liver HepG2 5 2.32193 0.665377130602114 0.969929995678059 DataSet_04_069
COL5A1 CHCHD3 CRISPR Liver HepG2 4 2 0.809658106518298 0.940294899673562 DataSet_04_067
COL5A1 CNOT7 CRISPR Liver HepG2 0.5 -1 0.667868534412452 0.798935898635793 DataSet_04_045
COL5A1 PAN2 CRISPR Liver HepG2 6.83333 2.77259 0.0298986341098791 0.107677050868614 DataSet_04_066
COL5A1 SEPT11 CRISPR Liver HepG2 4 2 0.171567775294493 0.417195086329413 DataSet_04_068
COL5A1 ABT1 shRNA Liver HepG2 0.368421 -1.44057 0.38941133031742 0.521000301889088 DataSet_04_052
COL5A1 CCAR1 shRNA Liver HepG2 20.6667 4.36923 0.0068086699076113 0.0390368078792812 DataSet_04_054
COL5A1 DDX1 shRNA Liver HepG2 0.125 -3 0.171113795986206 0.396303014177835 DataSet_04_057
COL5A1 NPM1 shRNA Liver HepG2 2.5 1.32193 0.859524339946819 0.986641141247727 DataSet_04_058
COL5A1 PRPF6 shRNA Liver HepG2 0.357143 -1.48543 0.572311144153335 0.763535135917712 DataSet_04_056
COL5A1 YBX3 shRNA Liver HepG2 0.583333 -0.777608 0.549926721204832 0.722636608784592 DataSet_02_98
COL5A1 DDX20 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.84615 0.884523 0.479177514581527 0.80369828898881 DataSet_04_050
COL5A1 NPM1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.65 -0.621488 0.653195281325476 0.805182105221812 DataSet_04_046
COL5A1 RIOK2 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.636364 -0.652077 0.728369444244636 0.952297327188961 DataSet_04_076
COL5A1 SEPT11 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.05263 1.03747 0.341232606822449 1 DataSet_04_077
COL5A1 CITED2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 5.64706 2.4975 0.0030310778884335 0.119535699006184 DataSet_02_38
COL5A1 DPF2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.529412 -0.917538 0.499573997127667 0.660275765624259 DataSet_02_14
COL5A1 HMGA1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.306122 -1.70782 0.422579353696738 0.763403094367102 DataSet_02_75
COL5A1 HMGN3 CRISPRi Haematopoietic_and_lymphoid_tissue K562 4.35294 2.12199 0.317809274619917 0.753134077425223 DataSet_02_45
COL5A1 LDB1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 4.05882 2.02106 0.0594539210450766 0.140414205299878 DataSet_02_35
COL5A1 NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.47059 1.30485 0.53654055320764 0.735813219111601 DataSet_02_32
COL5A1 SMARCA4 CRISPRi Haematopoietic_and_lymphoid_tissue K562 3.41176 1.77052 0.352658145363831 0.514645942987532 DataSet_02_47
COL5A1 SNW1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.46809 1.30339 0.0325070926597367 0.40817690914414 DataSet_02_49
COL5A1 TBL1XR1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 6.64706 2.73272 0.00208154222529054 0.0249183371235367 DataSet_02_43
COL5A1 TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 3.17647 1.66742 0.0559715427186771 0.123507062087106 DataSet_02_33
COL5A1 TLE2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.82353 0.866733 0.345738658947049 0.516683219023882 DataSet_02_53
COL5A1 ABT1 shRNA Haematopoietic_and_lymphoid_tissue K562 21 4.39232 0.235719757198513 0.389931468268356 DataSet_04_060
COL5A1 CNOT7 shRNA Haematopoietic_and_lymphoid_tissue K562 2.63636 1.39855 0.335206073800333 0.537589634490605 DataSet_04_061
COL5A1 HDGF shRNA Haematopoietic_and_lymphoid_tissue K562 4 2 0.838824997007549 0.908758529409085 DataSet_04_059
COL5A1 UBE2L3 shRNA Haematopoietic_and_lymphoid_tissue K562 5 2.32193 0.584622759045892 0.79938325486959 DataSet_04_062
COL5A1 PATZ1 siRNA Liver HepG2 3.87948 1.95586 3.186005e-09 8.390678e-05 DataSet_03_296
COL5A1 PATZ1 siRNA Liver HepG2 3.87948 1.95586 3.186005e-09 8.390678e-05 DataSet_03_297
COL5A1 EZH2 siRNA Uterus Hec-1A 1.74917 0.806667 7.148705e-06 1.114415e-03 DataSet_03_314
COL5A1 TET1 siRNA Lung A549 0.404483 -1.30585 - - DataSet_03_318
COL5A1 TET1 siRNA Lung A549 0.404483 -1.30585 - - DataSet_03_320
COL5A1 ZNF598 knockout Cervix HeLa 0.527764 -0.922036 1.904423e-03 1.0000000 DataSet_03_299
COL5A1 ELF3 CRISPR Bile_duct HBDEC2 4.02831 2.01017 1.479569e-06 1.395685e-04 DataSet_03_304
COL5A1 ELF3 knockdown Bile_duct HBDEC2 3.10091 1.63269 5.937224e-07 1.586152e-03 DataSet_03_305
COL5A1 SNAI2 shRNA Pancreas KLM1 0.164682 -2.60224 1.833191e-04 0.06186751 DataSet_03_307
COL5A1 EZH2 shRNA Mammary_gland MCF7 2.7991 1.48496 2.209952e-08 1.098872e-05 DataSet_03_331
COL5A1 BCL3 siRNA Central_nervous_system U87 1.53334 0.616679 3.841177e-05 1.215599e-03 DataSet_03_336
COL5A1 TET1 CRISPR Mammary_gland MDA-MB-231 0.106812 -3.22686 1.111009e-07 3.642558e-05 DataSet_03_347
COL5A1 ESR1 siRNA Mammary_gland MCF7 1.79866 0.846919 1.367630e-04 0.0099343018 DataSet_03_352
COL5A1 RUNX1 shRNA Haematopoietic_and_lymphoid_tissue OCI-AML5 2.62536 1.39251 2.758905e-01 5.161775e-01 DataSet_03_359
COL5A1 ARID2 shRNA Haematopoietic_and_lymphoid_tissue MM.1S 0.341049 -1.55195 2.416995e-01 3.490703e-01 DataSet_03_362
COL5A1 MYC siRNA Peripheral_blood T lymphocyte 3.72896 1.89877 6.246513e-01 0.812843693 DataSet_03_363
COL5A1 EP300 shRNA Mammary_gland MCF10AT 3.5 1.80736 4.879287e-03 0.048618007 DataSet_03_364
COL5A1 DNMT3A knockout Embryo_kidney HEK293T 45.6561 5.51274 - - DataSet_03_369
COL5A1 HNRNPU siRNA Colon RKO 1.59779 0.676079 - - DataSet_03_374
COL5A1 GLI1 siRNA Skeletal_muscle RMS13 0.59425 -0.750858 2.624234e-02 0.132524179 DataSet_03_375
COL5A1 EZH2 CRISPR Ovary SKOV3 0.349794 -1.51542 9.905739e-02 0.2729554969 DataSet_03_378
COL5A1 NFKB2 siRNA Bone_marrow U2OS 0.21956 -2.18731 1.893034e-04 0.05110355 DataSet_03_381
COL5A1 DNMT1 siRNA Skin Human melanoma cells 7.82833 2.9687 1.429278e-07 1.293015e-05 DataSet_03_382
COL5A1 TCF19 CRISPR Oral_squamous CAL27 2.37456 1.24766 1.326467e-04 0.0071319428 DataSet_03_383
COL5A1 KAT6A CRISPR Haematopoietic_and_lymphoid_tissue MOLM-13 0.652463 -0.616033 0.7211339561 0.9488745 DataSet_03_387
COL5A1 TRIM8 siRNA Mammary_gland MCF7 0.489185 -1.03155 4.700937e-05 0.0030017299 DataSet_03_388
COL5A1 YY1 knockdown Liver HepG2 5.25 2.39232 7.405430e-02 1.742776e-01 DataSet_03_390
COL5A1 ILF2 siRNA Stomach SGC-7901 4.43763 2.14979 0.4163539763 0.62879733 DataSet_03_393
COL5A1 ASXL1 CRISPR Embryo iPSC 5.16537 2.36887 0.0290541897 0.8048302 DataSet_03_394
COL5A1 IKZF2 CRISPR Lymph CAR T Cell 0.0217698 -5.52153 4.170241e-01 0.785717288 DataSet_03_397
COL5A1 TLE4 CRISPR Lymph CAR T Cell 0.0235943 -5.40542 4.348622e-01 0.71882415 DataSet_03_398
COL5A1 EHF shRNA Stomach MKN7 0.00194546 -9.00567 - - DataSet_03_402
COL5A1 JARID2 siRNA Adipose_tissue human adipose tissue derived stem cells 1.5188 0.60293 2.786546e-01 0.4870071 DataSet_03_403
COL5A1 CDK7 shRNA Bone_marrow D458 0.20303 -2.30023 1.281342e-03 0.08057741 DataSet_03_404
COL5A1 TFAP2A knockout Embryo H9 0.430219 -1.21686 1.181403e-03 0.02756260 DataSet_03_405
COL5A1 SATB2 CRISPR Colon Colon organoid 2 1 3.979752e-01 0.95735254 DataSet_03_406
COL5A1 CHD1 shRNA Prostate LNCaP 0.427935 -1.22454 9.726025e-04 5.792180e-02 DataSet_03_407
COL5A1 MAP3K7 shRNA Prostate LNCaP 0.43685 -1.19479 1.191984e-04 5.475222e-03 DataSet_03_408
COL5A1 SIRT1 siRNA Pancreas PANC1 4.1113 2.03959 7.509805e-06 0.007234717 DataSet_03_410
COL5A1 ZKSCAN3 CRISPR Colon HCT116 2.45455 1.29546 2.338966e-02 0.320292131 DataSet_03_415
COL5A1 FOXK2 shRNA Ovary OVCAR-5 0.625 -0.678072 2.359673e-01 0.45139695 DataSet_03_419
COL5A1 BRD4 CRISPR Lymph CD8+ T cells 0.105263 -3.24793 - - DataSet_03_420
COL5A1 MAEL CRISPR Liver Alexander cells 0.627907 -0.671377 - - DataSet_03_423
COL5A1 FOXP3 CRISPR Peripheral_blood Naive Treg 0.165138 -2.59826 6.782905e-01 0.846134537 DataSet_03_427
COL5A1 USP7 shRNA Skin xenograft cells 0.556331 -0.845985 0.29705630 0.4417890 DataSet_03_431
COL5A1 PLAG1 shRNA Cord_blood Lin-CD34+ HSPCs 0.285132 -1.8103 - - DataSet_03_432
COL5A1 POU2AF1 CRISPR Haematopoietic_and_lymphoid_tissue OCI-Ly7 0.214493 -2.221 2.099770e-02 0.406050444 DataSet_03_434
COL5A1 SUFU shRNA Mammary_gland HCC1954 cells 2.36596 1.24242 0.0687568911 0.5805438 DataSet_03_437
COL5A1 CAMTA1 knockout Embryo_kidney HEK293T 1.50126 0.586171 7.763328e-03 0.10788235 DataSet_03_448
COL5A1 CBX2 siRNA Mammary_gland MDA-MB-231 3.12796 1.64522 5.465214e-04 5.984481e-03 DataSet_03_450
COL5A1 CBX2 siRNA Mammary_gland MCF7 4.26671 2.09312 1.406910e-04 0.0016618947 DataSet_03_451
COL5A1 ZFP36L1 CRISPR Lung NCI-H1876 4.91798 2.29807 2.082988e-01 0.992381486 DataSet_03_454
COL5A1 SMARCA2 shRNA Lung HCC2302 0.000906583 -10.1073 1.325026e-20 1.581961e-17 DataSet_03_455
COL5A1 ARID1A shRNA Bile_duct MMNK1 0.145613 -2.77979 1.406871e-06 0.003233341 DataSet_03_458
COL5A1 IRF2 shRNA Cord_Blood CD34+ cells 0.593407 -0.752907 - - DataSet_03_460
COL5A1 TXNIP shRNA Cord_Blood CD34+ cells 1.89041 0.9187 - - DataSet_03_461
COL5A1 TXNIP shRNA Cord_blood ST3 1.97222 0.979822 6.492819e-02 0.3240140801 DataSet_03_462
COL5A1 PARP1 knockout Embryo_kidney HEK293a 0.356993 -1.48603 2.119145e-10 1.315174e-08 DataSet_03_464
COL5A1 SMARCA1 Cas13 Embryo_kidney HEK293T 0.192343 -2.37825 - - DataSet_03_466
COL5A1 SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 1.50866 0.593268 - - DataSet_03_467
COL5A1 WHSC1 siRNA Prostate PC3 1.76537 0.819974 2.454915e-03 0.07831401 DataSet_03_471
COL5A1 CREBBP CRISPR Lymph U2932 0.62963 -0.667425 6.967379e-01 1.0000000 DataSet_03_474
COL5A1 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 0.435897 -1.19794 0.5012202 0.8613018 DataSet_04_072
COL5A1 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.6288278 0.768612897 DataSet_04_074
Regulation Region
 
T(co)Fs that significantly regulate NONO by the evidences of both expression and ChIP-seq/motif
Expression Atlas of COL5A1
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines