Gene Overview
Target Gene: DUOX2
NCBI Official Symbol: DUOX2
Entrez ID: 50506
Ensembl ID: ENSG00000140279
Gene Full Name: dual oxidase 2
Strand: -
Gene Locus: 15q21.1
External Links:

DUOX2 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate DUOX2   
T(co)Fs that Repress DUOX2
The Intensity of the Gene Regulated by T(co)Fs:
DUOX2-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
DUOX2 SPDEF shRNA Mammary_gland MCF7 1.81844 0.8627 0.77264 0.99999 DataSet_01_107
DUOX2 ID1 siRNA Lung A549 0.28385 -1.81678 0.19057 0.4276 DataSet_01_117
DUOX2 ID1 siRNA Lung H1650 0.15423 -2.69685 0.0152 0.32206 DataSet_01_118
DUOX2 ZIC2 siRNA Pancreas PANC1 21.9555 4.45651 - - DataSet_01_121
DUOX2 FOXM1 siRNA Central_nervous_system U87 17.5664 4.13474 - - DataSet_01_122
DUOX2 HOXB7 siRNA Pancreas Capan-1 0.61796 -0.6944 0.01512 0.44724 DataSet_01_170
DUOX2 TP53 siRNA Lung SAECs 2.07595 1.05377 0.04377 0.3893 DataSet_01_175
DUOX2 CREB1 shRNA Parotid_gland HSY 0.09527 -3.39187 0.35524 0.97302 DataSet_01_195
DUOX2 TP63 siRNA Immortalized_keratinocyte HaCaT RG 0.59565 -0.74745 - - DataSet_01_196
DUOX2 TP63 siRNA Head_and_neck SCC-1 2.39037 1.25724 - - DataSet_01_198
DUOX2 TP63 siRNA Head_and_neck SCC-012 0.39023 -1.35761 - - DataSet_01_201
DUOX2 TP63 siRNA Head_and_neck SCC-6 0.46033 -1.11925 - - DataSet_01_202
DUOX2 HIC1 shRNA Mammary_gland HBL100 1.52421 0.60806 - - DataSet_01_205
DUOX2 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 8.13935 3.02491 - - DataSet_01_209
DUOX2 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 0.39946 -1.32389 - - DataSet_01_210
DUOX2 LIN28A siRNA Embryo H9 0.38663 -1.37097 0.00933 0.04746 DataSet_01_215
DUOX2 SNAI2 shRNA Skin Primary human keratinocytes 1.62386 0.69942 0.0106 0.04871 DataSet_01_225
DUOX2 KLF2 shRNA Bone_marrow RPMI8226 1.76108 0.81646 0.51018 0.90781 DataSet_01_226
DUOX2 FOXP1 siRNA Prostate LNCaP 1.52647 0.61019 0.00803 0.24494 DataSet_01_234
DUOX2 AR shRNA Prostate CWR22Pc 0.36033 -1.47261 0.18705 0.39534 DataSet_01_278
DUOX2 MSX1 siRNA Tooth Dental Pulp Cells 0.57987 -0.78621 0.45699 0.55751 DataSet_01_281
DUOX2 SP3 siRNA Haematopoietic_and_lymphoid_tissue JURKAT 0.40432 -1.30645 0.25837 0.90406 DataSet_01_290
DUOX2 TFAP4 siRNA Brain BE(2)-C 0.19854 -2.3325 0.35005 0.51625 DataSet_01_295
DUOX2 PTEN shRNA Lung HCC827 0.0636 -3.97479 0.00806 0.40778 DataSet_01_302
DUOX2 PTEN shRNA Mammary_gland SKBR3 0.38193 -1.3886 0.53128 0.83736 DataSet_01_303
DUOX2 OVOL2 siRNA Corneal_epithelial Corneal epithelial cells 2.41896 1.27439 0.08413 0.34434 DataSet_01_313
DUOX2 ARNT siRNA Upper_aerodigestive_tract HSC3 0.41055 -1.28438 - - DataSet_01_315
DUOX2 HOXC6 siRNA Prostate LNCaP 6.15929 2.62276 0.01231 0.99927 DataSet_01_333
DUOX2 GATA3 siRNA Oral_cavity OEC-M1 0.62255 -0.68373 0.50702 0.99787 DataSet_01_347
DUOX2 HIF1A siRNA Oral_cavity OEC-M1 1.63644 0.71056 0.50633 0.87577 DataSet_01_348
DUOX2 RBM17 shRNA Liver HepG2 0.32609 -1.61667 0.46934 0.70118 DataSet_02_100
DUOX2 SAFB2 shRNA Liver HepG2 2.34615 1.2303 0.2061 0.29996 DataSet_02_102
DUOX2 FIP1L1 shRNA Liver HepG2 5.11765 2.35548 0.00169 0.018 DataSet_02_103
DUOX2 HDGF shRNA Liver HepG2 2.03448 1.02466 0.02105 0.1182 DataSet_02_104
DUOX2 TAF15 shRNA Liver HepG2 12.75 3.67243 0.01672 0.04111 DataSet_02_106
DUOX2 SSB shRNA Liver HepG2 35 5.12928 6.28876e-05 0.00363 DataSet_02_107
DUOX2 ZNF622 shRNA Liver HepG2 12.7778 3.67557 0.01265 0.03292 DataSet_02_108
DUOX2 HNRNPUL1 shRNA Liver HepG2 2.30769 1.20645 0.11864 0.19523 DataSet_02_109
DUOX2 GTF2F1 shRNA Liver HepG2 11.5625 3.53138 0.00093 0.20753 DataSet_02_110
DUOX2 U2AF2 shRNA Liver HepG2 0.3913 -1.35364 0.47599 0.61314 DataSet_02_113
DUOX2 XRCC5 shRNA Liver HepG2 2.125 1.08746 0.36729 0.56466 DataSet_02_114
DUOX2 PCBP1 shRNA Liver HepG2 2.875 1.52356 0.22631 0.29965 DataSet_02_115
DUOX2 TARDBP shRNA Liver HepG2 0.14286 -2.80735 0.01457 0.04623 DataSet_02_116
DUOX2 SUB1 shRNA Liver HepG2 19.25 4.26679 0.00196 0.12645 DataSet_02_117
DUOX2 RBM25 shRNA Liver HepG2 5 2.32193 0.03457 0.08217 DataSet_02_119
DUOX2 PTBP1 shRNA Liver HepG2 3.625 1.85798 0.07987 0.11295 DataSet_02_120
DUOX2 PCBP2 shRNA Liver HepG2 2.25 1.16993 0.23287 0.4007 DataSet_02_123
DUOX2 FUS shRNA Liver HepG2 3.625 1.85798 0.00597 0.07459 DataSet_02_124
DUOX2 SNRNP70 shRNA Liver HepG2 10.2857 3.36257 0.00038 0.03074 DataSet_02_126
DUOX2 SRSF3 shRNA Liver HepG2 2.57143 1.36257 0.88408 0.93483 DataSet_02_127
DUOX2 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.07417 0.1469 DataSet_02_131
DUOX2 SRSF7 shRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.08227 0.30939 DataSet_02_133
DUOX2 PCBP2 shRNA Haematopoietic_and_lymphoid_tissue K562 3.5 1.80735 0.47743 0.62552 DataSet_02_135
DUOX2 HNRNPK shRNA Haematopoietic_and_lymphoid_tissue K562 6 2.58496 0.26662 0.48393 DataSet_02_136
DUOX2 RBM17 shRNA Haematopoietic_and_lymphoid_tissue K562 5.33333 2.41504 0.3337 0.60296 DataSet_02_138
DUOX2 RBFOX2 shRNA Haematopoietic_and_lymphoid_tissue K562 12 3.58496 0.02454 0.45829 DataSet_02_139
DUOX2 RBM34 shRNA Haematopoietic_and_lymphoid_tissue K562 3 1.58496 0.02605 0.22214 DataSet_02_141
DUOX2 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 5.33333 2.41504 0.21141 0.2918 DataSet_02_143
DUOX2 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 2 1 1 1 DataSet_02_144
DUOX2 DROSHA shRNA Haematopoietic_and_lymphoid_tissue K562 6.5 2.70044 0.43613 0.70392 DataSet_02_145
DUOX2 CCAR2 shRNA Haematopoietic_and_lymphoid_tissue K562 5.5 2.45943 0.10013 0.52666 DataSet_02_146
DUOX2 ILF3 shRNA Haematopoietic_and_lymphoid_tissue K562 15 3.90689 0.00141 0.2373 DataSet_02_148
DUOX2 NONO shRNA Haematopoietic_and_lymphoid_tissue K562 2.4 1.26303 0.13917 0.33342 DataSet_02_149
DUOX2 RBM39 shRNA Haematopoietic_and_lymphoid_tissue K562 5 2.32193 0.05164 0.25594 DataSet_02_151
DUOX2 ILF2 shRNA Haematopoietic_and_lymphoid_tissue K562 15.5 3.9542 0.04531 0.30885 DataSet_02_152
DUOX2 YBX3 shRNA Haematopoietic_and_lymphoid_tissue K562 11 3.45943 0.00299 0.41577 DataSet_02_153
DUOX2 FUS shRNA Haematopoietic_and_lymphoid_tissue K562 2 1 0.77689 0.88174 DataSet_02_155
DUOX2 HNRNPUL1 shRNA Haematopoietic_and_lymphoid_tissue K562 6 2.58496 0.71009 0.86905 DataSet_02_156
DUOX2 PSIP1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.66667 0.73697 0.48529 0.60917 DataSet_02_158
DUOX2 HNRNPL shRNA Haematopoietic_and_lymphoid_tissue K562 1.75 0.80735 0.22685 0.40979 DataSet_02_160
DUOX2 AGO1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.33333 1.22239 0.92817 0.98727 DataSet_02_162
DUOX2 SSB shRNA Haematopoietic_and_lymphoid_tissue K562 2.33333 1.22239 0.93184 0.97158 DataSet_02_164
DUOX2 U2AF1 shRNA Haematopoietic_and_lymphoid_tissue K562 2 1 0.04526 0.19423 DataSet_02_165
DUOX2 RBM22 shRNA Haematopoietic_and_lymphoid_tissue K562 15.5 3.9542 0.11404 0.22325 DataSet_02_168
DUOX2 U2AF2 shRNA Haematopoietic_and_lymphoid_tissue K562 2.5 1.32193 0.2909 0.4234 DataSet_02_170
DUOX2 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.00108 0.20622 DataSet_02_171
DUOX2 ZNF180 siRNA Haematopoietic_and_lymphoid_tissue K562 2.75 1.45943 0.12043 1 DataSet_02_177
DUOX2 VEZF1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.41353 1 DataSet_02_179
DUOX2 ZMIZ1 siRNA Haematopoietic_and_lymphoid_tissue K562 2.125 1.08746 0.09695 1 DataSet_02_181
DUOX2 MAFK siRNA Haematopoietic_and_lymphoid_tissue K562 4.66667 2.22239 0.26154 1 DataSet_02_183
DUOX2 KAT2B siRNA Haematopoietic_and_lymphoid_tissue K562 0.33333 -1.58496 0.48412 1 DataSet_02_184
DUOX2 CHD1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.125 -3 0.12976 1 DataSet_02_187
DUOX2 BACH1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.42857 -1.22239 0.0542 1 DataSet_02_188
DUOX2 MAFG siRNA Haematopoietic_and_lymphoid_tissue K562 0.42857 -1.22239 0.61619 1 DataSet_02_189
DUOX2 ARID3A siRNA Haematopoietic_and_lymphoid_tissue K562 0.41667 -1.26303 0.33994 1 DataSet_02_193
DUOX2 UBTF siRNA Haematopoietic_and_lymphoid_tissue K562 0.25 -2 0.45628 1 DataSet_02_198
DUOX2 MAZ siRNA Haematopoietic_and_lymphoid_tissue K562 3.25 1.70044 0.64764 1 DataSet_02_199
DUOX2 E2F4 siRNA Haematopoietic_and_lymphoid_tissue K562 0.57143 -0.80735 0.20479 1 DataSet_02_200
DUOX2 TAL1 siRNA Haematopoietic_and_lymphoid_tissue K562 2.25 1.16993 0.22334 1 DataSet_02_201
DUOX2 RCOR1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.4 -1.32193 0.55643 1 DataSet_02_204
DUOX2 ZFX siRNA Mammary_gland MCF7 0.17647 -2.5025 0.61327 0.78641 DataSet_02_206
DUOX2 AR siRNA Prostate abl cells 2.50365 1.32403 0.170404771891118 0.999852161656754 DataSet_03_004
DUOX2 AR siRNA Prostate LNCaP 0.466667 -1.09954 0.0742050300170655 1 DataSet_03_005
DUOX2 ARID2 CRISPR Liver JHH4 0.478672 -1.06289 0.381301843348474 1 DataSet_03_015
DUOX2 ASCL1 siRNA Lung DMS79 0.534091 -0.904843 0.0553990512468805 0.683685280198898 DataSet_03_016
DUOX2 BCL6 siRNA Lymph OCI-Ly7 DLBCL 3.43488 1.78026 0.139742343321766 0.782289370094745 DataSet_03_025
DUOX2 GATA2 siRNA Uterus Decidual stromal cells 2.15943 1.11065 0.0526563494704702 0.649358341562091 DataSet_03_100
DUOX2 GATA6 siRNA Stomach AGS 0.231581 -2.11041 0.0177564348367964 0.356693503145479 DataSet_03_108
DUOX2 GATA6 siRNA Stomach KatoIII 1.63521 0.709474 0.00272279908380602 0.243521825292446 DataSet_03_109
DUOX2 GATA6 siRNA Stomach YCC3 0.639689 -0.644558 0.381409234153939 0.870856156745891 DataSet_03_110
DUOX2 GFP siRNA Mammary_gland BT-20 cells 1.66667 0.736966 0.0868702831141833 0.582206573414568 DataSet_03_111
DUOX2 GRHL3 siRNA Skin Primary neonatal keratinocytes 0.578296 -0.790121 0.000242914621844904 0.07650825799107 DataSet_03_113
DUOX2 HIF3A siRNA Liver Hep3B 0.650671 -0.62 0.0606707053130461 1 DataSet_03_120
DUOX2 HIF3A siRNA Liver Hep3B 0.650671 -0.62 0.0606707053130461 1 DataSet_03_121
DUOX2 HNF4a siRNA Liver HepG2 2.67442 1.41922 0.119079265093104 0.73218449190883 DataSet_03_126
DUOX2 IRF4 siRNA Skin Cutaneous T cell lymphoma HuT-102 cells 1.64989 0.722372 0.366021748971555 0.999948959532916 DataSet_03_134
DUOX2 KLF5 siRNA Stomach KatoIII 0.136795 -2.86992 0.00377881304281116 0.17712163732051 DataSet_03_150
DUOX2 MEF2D shRNA Liver HuH7 1.98063 0.985956 - - DataSet_03_162
DUOX2 MEF2D siRNA Liver HuH7 0.539635 -0.889945 - - DataSet_03_163
DUOX2 MITF siRNA Skin Ma-Mel-15 2.01385 1.00996 0.032770864800029 0.353558387699473 DataSet_03_166
DUOX2 MYB siRNA Cord_Blood CD34+ progenitor cells 3.46942 1.7947 - - DataSet_03_170
DUOX2 MYC siRNA Colon HT29 0.366231 -1.44918 - - DataSet_03_177
DUOX2 MYC siRNA Central_nervous_system DAOY M2.1 1.67121 0.740895 0.000473263582161657 0.001382133900433 DataSet_03_178
DUOX2 NR2F2 siRNA Uterus Primary eutopic stromal cells 0.659227 -0.601153 0.0713370237927652 0.99947668859931 DataSet_03_202
DUOX2 PHB shRNA Embryo Embryonic stem cells (ESCs) 0.376889 -1.40779 0.168972298683602 0.291064079652337 DataSet_03_211
DUOX2 PRRX1 CRISPR Neuroblastoma 691-MES 0.499823 -1.00051 0.0686587833304911 0.89189998148014 DataSet_03_217
DUOX2 STAT3 CRISPR Embryo hESC 0.0725229 -3.78542 0.119118198604343 0.191445035318795 DataSet_03_258
DUOX2 TFE3 siRNA Kidney UOK257-2 0.0834087 -3.58366 - - DataSet_03_275
DUOX2 TP63 siRNA Skin Primary neonatal keratinocytes 0.656161 -0.607879 0.00300114838739069 0.0213309734962055 DataSet_03_281
DUOX2 ZNF746 siRNA Colon HCT116 1.53901 0.622 - - DataSet_03_293
DUOX2 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 0.4 -1.32193 0.367375230235048 0.776017735219839 DataSet_04_001
DUOX2 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 3.53846 1.82312 0.00554044678520432 0.0524724097871993 DataSet_04_002
DUOX2 CHCHD3 CRISPR Haematopoietic_and_lymphoid_tissue K562 4.84615 2.27684 0.027424009932002 0.871203452435347 DataSet_04_003
DUOX2 CIZ1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.333333 -1.58496 0.0286399445768612 0.0754269886291503 DataSet_04_004
DUOX2 DDX59 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.76471 0.819428 0.00221976597437882 0.458197110673681 DataSet_04_006
DUOX2 E4F1 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.78571 0.836501 0.28516084995531 0.678154042619166 DataSet_04_007
DUOX2 EIF2AK2 CRISPR Haematopoietic_and_lymphoid_tissue K562 11 3.45943 0.0269083600547358 0.475866920558352 DataSet_04_008
DUOX2 MARK2 shRNA Haematopoietic_and_lymphoid_tissue K562 16.1667 4.01495 6.94531467000323e-05 0.0116174763701763 DataSet_04_012
DUOX2 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 72.2188 6.1743 0.0486646215383349 0.134845656657745 DataSet_04_014
DUOX2 SMAD5 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.428571 -1.22239 0.0457192524437708 0.417780416390472 DataSet_04_020
DUOX2 YBX1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.0939984914383945 0.531315694668649 DataSet_04_022
DUOX2 ZNF574 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.259259 -1.94753 0.00339941877326694 0.113567209536072 DataSet_04_023
DUOX2 CTCF CRISPR Liver HepG2 0.416667 -1.26303 0.0625733772116112 0.86679156788789 DataSet_04_027
DUOX2 ERN1 CRISPR Liver HepG2 1.56757 0.648528 0.205379195433753 0.405043743762923 DataSet_04_029
DUOX2 NFX1 CRISPR Liver HepG2 0.266667 -1.90689 0.0339793711467164 0.0776757453604022 DataSet_04_032
DUOX2 PAN2 CRISPR Liver HepG2 3.5 1.80736 0.0979225930633924 0.252063850271273 DataSet_04_033
DUOX2 SMAD2 CRISPR Liver HepG2 0.476191 -1.07039 0.0790633382739347 0.621153619552668 DataSet_04_034
DUOX2 SMAD4 CRISPR Liver HepG2 0.56 -0.836501 0.0855098431737508 0.216379265632169 DataSet_04_035
DUOX2 SMAD5 CRISPR Liver HepG2 1.75 0.807355 0.193217350320514 0.586798378491902 DataSet_04_036
DUOX2 ACTN4 CRISPR Liver HepG2 20.6 4.36457 0.00419124932082159 0.0424667285995555 DataSet_04_042
DUOX2 APTX CRISPR Liver HepG2 0.416667 -1.26303 0.219294428989183 0.824268978173362 DataSet_04_069
DUOX2 PAN2 CRISPR Liver HepG2 0.56 -0.836501 0.201271845610283 0.364725564360281 DataSet_04_066
DUOX2 RIOK2 CRISPR Liver HepG2 0.477612 -1.06609 0.308489097760103 1 DataSet_04_070
DUOX2 ABT1 shRNA Liver HepG2 90.8 6.50462 6.33934931445203e-07 0.00102327025477054 DataSet_04_052
DUOX2 CALR shRNA Liver HepG2 2.93333 1.55254 0.170314538608919 0.285881571171878 DataSet_04_053
DUOX2 DDX1 shRNA Liver HepG2 0.5 -1 0.429747219261908 0.661231045187435 DataSet_04_057
DUOX2 PRPF6 shRNA Liver HepG2 0.375 -1.41504 0.454650737406171 0.668152970213249 DataSet_04_056
DUOX2 UBE2L3 shRNA Liver HepG2 34.6 5.1127 0.000105174530536278 0.00595433009880097 DataSet_04_055
DUOX2 YBX3 shRNA Liver HepG2 2.30769 1.20645 0.101755107677407 0.250528593683709 DataSet_02_98
DUOX2 ACTN4 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.416667 -1.26303 0.427766083580724 0.635555503404292 DataSet_04_048
DUOX2 SEPT11 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.36 -1.47393 0.340934574380835 1 DataSet_04_077
DUOX2 SMG5 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.96 0.970854 0.539747283697143 0.83817561788323 DataSet_04_073
DUOX2 SNW1 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.76 0.815575 0.264794477838228 0.424446172768985 DataSet_04_049
DUOX2 CITED2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.625 0.70044 0.55855454803971 0.768239305223446 DataSet_02_38
DUOX2 DPF2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.541667 -0.884523 0.128284908837348 0.243831427598815 DataSet_02_14
DUOX2 ERF CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.416667 -1.26303 0.0970059412483888 0.210682007683886 DataSet_02_34
DUOX2 HMGA1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 3.35 1.74416 0.149216841295354 0.545419951332337 DataSet_02_75
DUOX2 HMGN3 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.35417 1.23522 0.17817870072936 0.665377916225149 DataSet_02_45
DUOX2 LDB1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.541667 -0.884523 0.158216868344307 0.295456505918897 DataSet_02_35
DUOX2 NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 4.20833 2.07325 0.101711042890984 0.418357129540174 DataSet_02_32
DUOX2 SMARCA4 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.479167 -1.0614 0.0703271619802878 0.154466614736593 DataSet_02_47
DUOX2 SNW1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.37931 -1.39855 0.363329406906041 0.754511678318881 DataSet_02_49
DUOX2 TBL1XR1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.4375 -1.19265 0.113050809799072 0.246615365796822 DataSet_02_43
DUOX2 TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.3125 -1.67807 0.0408678417552721 0.0969077303132294 DataSet_02_33
DUOX2 TLE2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2 1 0.0148373575444356 0.0665263269150156 DataSet_02_53
DUOX2 CCAR1 shRNA Haematopoietic_and_lymphoid_tissue K562 36 5.16993 0.219638667532898 0.398841889150432 DataSet_04_064
DUOX2 CNOT7 shRNA Haematopoietic_and_lymphoid_tissue K562 44.5 5.47573 0.0032051776833013 0.0567969695526302 DataSet_04_061
DUOX2 DDX1 shRNA Haematopoietic_and_lymphoid_tissue K562 11 3.45943 0.607781820089855 0.891504337785736 DataSet_04_063
DUOX2 HDGF shRNA Haematopoietic_and_lymphoid_tissue K562 6 2.58496 0.191532177501247 0.299857025805358 DataSet_04_059
DUOX2 UBE2L3 shRNA Haematopoietic_and_lymphoid_tissue K562 5.5 2.45943 0.254509814893246 0.508186082357802 DataSet_04_062
DUOX2 NFKBIZ knockout Colon Colon organoid 0.157091 -2.67033 2.713456e-02 0.620790401 DataSet_03_323
DUOX2 SMARCA4 siRNA Colon HCT116 2.36566 1.24224 3.705996e-02 6.510331e-01 DataSet_03_301
DUOX2 SMARCA4 siRNA Colon HCT116 0.36237 -1.46446 2.326311e-03 0.1301247 DataSet_03_302
DUOX2 ELF3 CRISPR Bile_duct HBDEC2 0.458608 -1.12467 7.668051e-04 5.049515e-03 DataSet_03_304
DUOX2 HDAC4 siRNA Liver human hepatocytes 0.633592 -0.658375 9.001944e-07 3.248652e-04 DataSet_03_345
DUOX2 SNAI2 shRNA Pancreas pancreatic cancer stem cells 1.89113 0.919248 9.047566e-02 0.6510154 DataSet_03_306
DUOX2 BRCA1 siRNA Mammary_gland MCF7 0.325801 -1.61794 5.131739e-02 0.9999931 DataSet_03_308
DUOX2 RUNX1 shRNA Haematopoietic_and_lymphoid_tissue OCI-AML5 0.263254 -1.92547 4.884310e-01 7.149559e-01 DataSet_03_359
DUOX2 NCOA2 siRNA Uterus endometrial stromal cells 0.4 -1.32193 0.2004894431 1 DataSet_03_360
DUOX2 ARID2 shRNA Haematopoietic_and_lymphoid_tissue MM.1S 7.14499 2.83693 2.559635e-01 3.666837e-01 DataSet_03_362
DUOX2 TP53 knockout Stomach SNU1 0.182601 -2.45324 0.3202102460 0.9301241 DataSet_03_365
DUOX2 ZNF148 shRNA Mammary_gland MDA-MB-231 0.303108 -1.7221 4.254412e-02 0.160093927 DataSet_03_366
DUOX2 ABL1 shRNA Liver HuH7 0.53331 -0.906954 1.108865e-03 0.0066877651 DataSet_03_367
DUOX2 USP22 shRNA Liver PLC_PRF_5 cells 0.0579585 -4.10884 5.954411e-04 0.05559130 DataSet_03_368
DUOX2 TPR shRNA Bone_marrow U2OS 1.73984 0.798955 8.403399e-02 4.300028e-01 DataSet_03_370
DUOX2 GLI1 siRNA Skeletal_muscle RMS13 2.75124 1.46008 1.806962e-02 0.106474367 DataSet_03_375
DUOX2 SMARCA2 shRNA Lung NCI-H1944 1.53333 0.616671 1.727741e-01 5.690372e-01 DataSet_03_377
DUOX2 EZH2 CRISPR Ovary SKOV3 4 2 2.746599e-01 0.4966825035 DataSet_03_378
DUOX2 NFKB2 siRNA Bone_marrow U2OS 2 1 4.464682e-01 0.67239995 DataSet_03_381
DUOX2 TRIM8 siRNA Mammary_gland MCF7 0.538462 -0.893085 5.162120e-01 0.6963128667 DataSet_03_388
DUOX2 NFKBIA shRNA Bone_marrow U2OS 0.0102926 -6.60224 7.421594e-01 0.89048631 DataSet_03_389
DUOX2 KDM5A CRISPR Lung GLC16 3.27689 1.71233 1.417651e-01 0.259790759 DataSet_03_392
DUOX2 ASXL1 CRISPR Embryo iPSC 9.02234 3.1735 0.0031661678 0.8024343 DataSet_03_394
DUOX2 BMI1 shRNA Bile_duct QBC-939 0.429103 -1.22061 1.749834e-02 0.0602610669 DataSet_03_395
DUOX2 RELA CRISPR Brain T30 2.72994 1.44887 0.5066220766 0.8579919 DataSet_03_399
DUOX2 EHF shRNA Stomach MKN7 0.0871469 -3.52041 - - DataSet_03_402
DUOX2 TFAP2A knockout Embryo H9 0.384615 -1.37851 3.006155e-02 0.11008866 DataSet_03_405
DUOX2 CHD1 shRNA Prostate LNCaP 0.113402 -3.14048 1.344850e-01 6.643582e-01 DataSet_03_407
DUOX2 MAP3K7 shRNA Prostate LNCaP 0.201031 -2.31451 5.092050e-01 7.098061e-01 DataSet_03_408
DUOX2 USP22 shRNA Liver HuH7 0.272347 -1.87648 - - DataSet_03_411
DUOX2 E2F2 siRNA Prostate LNCaP 2.07692 1.05445 4.825249e-02 1.829584e-01 DataSet_03_414
DUOX2 FOXK2 shRNA Ovary OVCAR-5 0.1875 -2.41504 2.923430e-02 0.13821102 DataSet_03_419
DUOX2 BRD4 CRISPR Lymph CD8+ T cells 0.333333 -1.58496 - - DataSet_03_420
DUOX2 FOXP3 CRISPR Peripheral_blood Naive Treg 0.181818 -2.45943 1.739986e-01 0.530672752 DataSet_03_427
DUOX2 USP7 shRNA Skin xenograft cells 0.631579 -0.662965 0.33375269 0.4745846 DataSet_03_431
DUOX2 POU2AF1 CRISPR Haematopoietic_and_lymphoid_tissue OCI-Ly7 0.217235 -2.20267 1.738877e-01 0.536920230 DataSet_03_434
DUOX2 EP300 knockout Pancreas HPAF-II orthotopic cells 0.415385 -1.26748 9.654737e-02 2.311381e-01 DataSet_03_436
DUOX2 SUFU shRNA Mammary_gland HCC1954 cells 0.5 -1 0.3216134124 0.6455297 DataSet_03_437
DUOX2 CIC knockout Brain Immortalized Astrocyte Cells 4.75 2.24793 3.393916e-01 7.558017e-01 DataSet_03_438
DUOX2 PURA siRNA Cervix HeLa 0.333333 -1.58496 1.591768e-01 0.382849032 DataSet_03_444
DUOX2 CAMTA1 knockout Embryo_kidney HEK293T 2.11111 1.078 5.352489e-01 0.65742840 DataSet_03_448
DUOX2 CBX2 siRNA Mammary_gland MDA-MB-231 0.399089 -1.32522 1.143257e-01 2.677896e-01 DataSet_03_450
DUOX2 CBX2 siRNA Mammary_gland MCF7 0.464078 -1.10756 5.535393e-01 0.7132421719 DataSet_03_451
DUOX2 ZFP36L1 CRISPR Lung NCI-H1876 0.407572 -1.29488 7.654617e-01 0.992664775 DataSet_03_454
DUOX2 ARID1A shRNA Bile_duct MMNK1 0.518351 -0.947999 1.100519e-01 0.354860451 DataSet_03_458
DUOX2 IRF2 shRNA Cord_Blood CD34+ cells 4.25 2.08746 - - DataSet_03_460
DUOX2 TXNIP shRNA Cord_Blood CD34+ cells 6.5 2.70044 - - DataSet_03_461
DUOX2 TXNIP shRNA Cord_blood ST3 5.16667 2.36923 3.993505e-02 0.2739314134 DataSet_03_462
DUOX2 SMARCA1 Cas13 Embryo_kidney HEK293T 0.25 -2 - - DataSet_03_466
DUOX2 SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 5 2.32193 - - DataSet_03_467
DUOX2 SMARCA1 shRNA Embryo_kidney HEK293T 0.25 -2 - - DataSet_03_468
DUOX2 LIN28A siRNA Mammary_gland MCF7M 0.65946 -0.600643 7.315622e-01 0.9498314 DataSet_03_469
DUOX2 LIN28A siRNA Mammary_gland MCF7M 0.65946 -0.600643 7.315622e-01 0.9498314 DataSet_03_470
DUOX2 EZH2 siRNA Prostate LNCaP 0.451779 -1.14631 - - DataSet_03_472
DUOX2 CHCHD3 CRISPR Haematopoietic_and_lymphoid_tissue K562 4.84615 2.27684 0.07179569 0.8523564 DataSet_04_071
DUOX2 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 0.4 -1.32193 0.2971169 0.7334424 DataSet_04_072
DUOX2 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 3.53846 1.82312 0.04149676 0.109578095 DataSet_04_074
Regulation Region
 
T(co)Fs that significantly regulate CNOT7 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of DUOX2
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines