Gene Overview
Target Gene: IFIT3
NCBI Official Symbol: IFIT3
Entrez ID: 3437
Ensembl ID: ENSG00000119917
Gene Full Name: interferon induced protein with tetratricopeptide repeats 3
Strand: +
Gene Locus: 10q23.31
External Links:

IFIT3 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate IFIT3   
T(co)Fs that Repress IFIT3
The Intensity of the Gene Regulated by T(co)Fs:
IFIT3-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
IFIT3 HNF1B shRNA Ovary RMG2 1.94791 0.96193 2.72748e-05 0.00021 DataSet_01_103
IFIT3 ARID1A shRNA Ovary OSE4 0.42203 -1.24457 - - DataSet_01_108
IFIT3 ID1 siRNA Lung A549 10.4845 3.39018 0.00187 0.09914 DataSet_01_117
IFIT3 GATA3 siRNA Mammary_gland MCF7 0.317 -1.65743 3.69271e-05 0.00145 DataSet_01_120
IFIT3 ZIC2 siRNA Pancreas PANC1 3.92857 1.974 - - DataSet_01_121
IFIT3 FOXM1 siRNA Central_nervous_system U87 2.43622 1.28465 - - DataSet_01_122
IFIT3 ZNF91 siRNA Gastrointestinal_tissue GIST-T1 1.52429 0.60813 0.01727 0.10112 DataSet_01_123
IFIT3 ZNF85 siRNA Gastrointestinal_tissue GIST-T1 1.51406 0.59842 0.01864 0.0526 DataSet_01_126
IFIT3 ZNF254 siRNA Gastrointestinal_tissue GIST-T1 0.60975 -0.7137 0.00759 0.04733 DataSet_01_127
IFIT3 EGR4 siRNA Lung SBC-5 0.62801 -0.67114 0.07498 0.40865 DataSet_01_132
IFIT3 SPDEF shRNA Mammary_gland MCF7 5.19977 2.37845 2.897e-05 0.00788 DataSet_01_135
IFIT3 POLR3A siRNA Mammary_gland MCF7 0.64813 -0.62563 - - DataSet_01_139
IFIT3 TAL1 shRNA Umbilical_cord_blood ECFCs 2.94693 1.55921 0.10249 0.62511 DataSet_01_152
IFIT3 ZFX shRNA Central_nervous_system DAOY 0.64356 -0.63585 0.09044 0.99991 DataSet_01_157
IFIT3 ELK1 siRNA Peripheral_blood CD4+ T cells 14.0552 3.81303 2.51109e-07 0.00012 DataSet_01_162
IFIT3 JUN siRNA Peripheral_blood CD4+ T cells 8935.65 13.1254 0.00055 0.01049 DataSet_01_164
IFIT3 MAF siRNA Peripheral_blood CD4+ T cells 16.4582 4.04074 1.03639e-07 7.19392e-05 DataSet_01_165
IFIT3 NFATC3 siRNA Peripheral_blood CD4+ T cells 8394.41 13.0352 0.001 0.02336 DataSet_01_166
IFIT3 HOXB7 siRNA Pancreas Capan-1 1.57423 0.65465 0.01333 0.43809 DataSet_01_170
IFIT3 FOSL1 siRNA Mammary_gland BT549 1.71907 0.78163 3.04568e-05 0.00309 DataSet_01_171
IFIT3 JUN siRNA Mammary_gland BT549 2.18206 1.12569 8.99541e-06 0.00203 DataSet_01_172
IFIT3 ESRRG siRNA Placenta_tissue Trophoblast cells 0.48475 -1.0447 0.20841 0.64084 DataSet_01_173
IFIT3 STAT3 siRNA Oesophagus OE21 1.65596 0.72767 0.02807 0.45914 DataSet_01_180
IFIT3 TP63 shRNA Bladder UC14 1.73448 0.7945 9.97393e-05 0.00152 DataSet_01_183
IFIT3 GABPA shRNA Prostate C4-2B 1559.38 10.6067 0.23977 0.43934 DataSet_01_190
IFIT3 GABPA shRNA Prostate LNCaP 1133.09 10.1461 0.46339 0.7048 DataSet_01_191
IFIT3 CREB1 shRNA Parotid_gland H3118 MEC 2.2332 1.15911 0.17786 0.53839 DataSet_01_194
IFIT3 TP63 siRNA Head_and_neck SCC-1 1.87775 0.90901 - - DataSet_01_198
IFIT3 TP63 siRNA Head_and_neck SCC-1 2.63846 1.39969 - - DataSet_01_199
IFIT3 TP63 siRNA Head_and_neck SCC-6 3.32256 1.7323 - - DataSet_01_202
IFIT3 XBP1 shRNA Mammary_gland MDA-MB-231 3.75412 1.90847 3.09353e-06 0.00123 DataSet_01_204
IFIT3 MITF shRNA Skin COLO829 4.16448 2.05814 1.05733e-05 0.00154 DataSet_01_207
IFIT3 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 0.57775 -0.79148 - - DataSet_01_210
IFIT3 EGR3 shRNA Prostate M12 0.52756 -0.92258 0.27714 0.51884 DataSet_01_212
IFIT3 BCLAF1 shRNA Colon RKO 0.591 -0.75876 - - DataSet_01_214
IFIT3 LIN28A siRNA Embryo H9 5.29972 2.40592 1.06477e-05 0.00088 DataSet_01_215
IFIT3 KLF9 siRNA Liver HepG2 2.28397 1.19154 1.57027e-09 1.46514e-07 DataSet_01_222
IFIT3 FOXM1 siRNA Mammary_gland MCF7 33.914 5.08381 0.00052 0.07321 DataSet_01_223
IFIT3 SNAI2 shRNA Skin Primary human keratinocytes 0.24954 -2.00268 8.85808e-05 0.00742 DataSet_01_225
IFIT3 KLF2 shRNA Bone_marrow RPMI8226 3.11125 1.63749 0.04372 0.60056 DataSet_01_226
IFIT3 JUN shRNA Soft_tissue LP6 1.52794 0.61159 0.24419 0.70975 DataSet_01_230
IFIT3 MYC shRNA Soft_tissue HT1080 21.8014 4.44635 - - DataSet_01_237
IFIT3 STAT5 shRNA Haematopoietic_and_lymphoid_tissue K562 1.95862 0.96984 0.00048 0.00431 DataSet_01_239
IFIT3 TWIST1 shRNA Stomach CAF32 0.18636 -2.42383 3.32662e-05 0.01146 DataSet_01_253
IFIT3 TWIST1 shRNA Stomach CAF 0.47502 -1.07394 0.07062 0.56934 DataSet_01_254
IFIT3 YBX1 shRNA Mammary_gland MDA 0.61742 -0.69568 2.85014e-06 5.57872e-05 DataSet_01_255
IFIT3 YBX1 shRNA Mammary_gland MDA 0.57822 -0.7903 0.0068 0.0284 DataSet_01_259
IFIT3 SOX4 shRNA Mammary_gland MDA-MB-231 2.05299 1.03773 0.00012 0.01013 DataSet_01_260
IFIT3 SALL4 shRNA Lung H661 0.08814 -3.50399 0.0043 0.08352 DataSet_01_277
IFIT3 STAT5 shRNA Prostate CWR22Pc 2.59966 1.37832 0.03715 0.12368 DataSet_01_279
IFIT3 ESRRA shRNA Embryo_kidney 293T 2.16368 1.11349 0.38156 0.83849 DataSet_01_280
IFIT3 POSTN shRNA Brain GSC272 0.33127 -1.59393 0.04413 0.53257 DataSet_01_293
IFIT3 TFAP4 siRNA Brain BE(2)-C 0.10364 -3.27033 0.19657 0.51625 DataSet_01_295
IFIT3 MYCN siRNA Brain BE(2)-C 1.87734 0.90869 0.81595 1 DataSet_01_296
IFIT3 ARID1B shRNA Liver IRM90 1.86131 0.89632 0.00038 0.00717 DataSet_01_298
IFIT3 SOX17 siRNA Umbilical_vein HUVEC 0.47178 -1.08382 0.14126 0.99998 DataSet_01_300
IFIT3 PTEN shRNA Skin A431 2.95998 1.56559 0.00041 0.0655 DataSet_01_301
IFIT3 PTEN shRNA Mammary_gland SKBR3 0.39811 -1.32875 0.09522 0.60447 DataSet_01_303
IFIT3 ETV5 siRNA Soft_tissue hADSC 3.76256 1.91172 1.55985e-07 0.00025 DataSet_01_304
IFIT3 BRD4 siRNA Ovary Ovcar8 0.45364 -1.14038 0.00011 0.00214 DataSet_01_311
IFIT3 TFAP2C siRNA Lung NCI-H292 4.8302 2.27208 - - DataSet_01_312
IFIT3 ARNT siRNA Upper_aerodigestive_tract HSC3 0.57409 -0.80066 - - DataSet_01_315
IFIT3 ERG siRNA Cervix HeLa 2.9355 1.55361 3.13271e-09 4.30765e-08 DataSet_01_316
IFIT3 ELK3 shRNA Mammary_gland MDA-MB-231 0.11983 -3.06099 1.43118e-05 0.00016 DataSet_01_318
IFIT3 MYC siRNA Colon HCT116 4.58335 2.1964 1.49601e-05 8.5008e-05 DataSet_01_324
IFIT3 TP63 shRNA Head_and_neck FaDU 1.57253 0.65308 7.76571e-05 0.00179 DataSet_01_327
IFIT3 TP63 shRNA Head_and_neck FaDU 1.57253 0.65308 7.76571e-05 0.00179 DataSet_01_330
IFIT3 TOX shRNA Haematopoietic_and_lymphoid_tissue HPB-ALL 2.34651 1.23052 0.0048 0.63404 DataSet_01_332
IFIT3 REST siRNA Skin NHEK 1.94037 0.95634 0.02708 0.16774 DataSet_01_337
IFIT3 KLF7 siRNA Embryo HCE 0.4023 -1.31367 0.3159 0.67517 DataSet_01_340
IFIT3 SOX2 shRNA Neuroepithelium HF2303 0.62952 -0.66768 0.1571 1 DataSet_01_349
IFIT3 ELK1 siRNA Mammary_gland MDA-MB-231 1.98396 0.98838 - - DataSet_01_354
IFIT3 PAX3 shRNA Soft_tissue Rh30 2.92685 1.54935 - - DataSet_01_359
IFIT3 RBM17 shRNA Liver HepG2 0.48413 -1.04654 0.00546 0.26816 DataSet_02_100
IFIT3 RBFOX2 shRNA Liver HepG2 0.61111 -0.71049 0.10645 0.65168 DataSet_02_101
IFIT3 SAFB2 shRNA Liver HepG2 0.61441 -0.70273 0.14266 0.22608 DataSet_02_102
IFIT3 U2AF2 shRNA Liver HepG2 1.7665 0.82089 0.77351 0.8542 DataSet_02_105
IFIT3 SSB shRNA Liver HepG2 2.4067 1.26706 0.00059 0.00608 DataSet_02_107
IFIT3 ZNF622 shRNA Liver HepG2 0.28421 -1.81497 0.00054 0.007 DataSet_02_108
IFIT3 HNRNPUL1 shRNA Liver HepG2 1.59746 0.67578 0.07521 0.13984 DataSet_02_109
IFIT3 GTF2F1 shRNA Liver HepG2 1.60914 0.68629 0.02408 0.26082 DataSet_02_110
IFIT3 PCBP1 shRNA Liver HepG2 1.64078 0.71438 0.01779 0.04626 DataSet_02_115
IFIT3 PTBP1 shRNA Liver HepG2 1.96602 0.97528 0.05804 0.08656 DataSet_02_120
IFIT3 EWSR1 shRNA Liver HepG2 1.59524 0.67377 0.01429 0.0699 DataSet_02_122
IFIT3 PCBP2 shRNA Liver HepG2 1.8934 0.92098 0.01311 0.08454 DataSet_02_123
IFIT3 FUS shRNA Liver HepG2 1.6599 0.7311 0.06802 0.20561 DataSet_02_124
IFIT3 SNRNP70 shRNA Liver HepG2 2.67513 1.41961 0.02421 0.0798 DataSet_02_126
IFIT3 POLR2G shRNA Haematopoietic_and_lymphoid_tissue K562 0.53552 -0.90099 0.06766 0.71542 DataSet_02_130
IFIT3 SRSF7 shRNA Haematopoietic_and_lymphoid_tissue K562 0.60284 -0.73016 0.10522 0.33864 DataSet_02_133
IFIT3 RBFOX2 shRNA Haematopoietic_and_lymphoid_tissue K562 2.01786 1.01282 0.01471 0.45812 DataSet_02_139
IFIT3 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.53125 -0.91254 0.02311 0.05974 DataSet_02_143
IFIT3 FIP1L1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.55952 0.64111 0.03847 0.13807 DataSet_02_147
IFIT3 ILF3 shRNA Haematopoietic_and_lymphoid_tissue K562 2.26786 1.18133 0.01083 0.24383 DataSet_02_148
IFIT3 SAFB2 shRNA Haematopoietic_and_lymphoid_tissue K562 1.54054 0.62344 0.07743 0.51146 DataSet_02_150
IFIT3 ILF2 shRNA Haematopoietic_and_lymphoid_tissue K562 4 2 0.00247 0.23369 DataSet_02_152
IFIT3 YBX3 shRNA Haematopoietic_and_lymphoid_tissue K562 1.51786 0.60204 0.06015 0.49492 DataSet_02_153
IFIT3 XRCC5 shRNA Haematopoietic_and_lymphoid_tissue K562 1.65854 0.72991 0.02794 0.5977 DataSet_02_159
IFIT3 HNRNPL shRNA Haematopoietic_and_lymphoid_tissue K562 2.19355 1.13327 0.01325 0.12656 DataSet_02_160
IFIT3 SSB shRNA Haematopoietic_and_lymphoid_tissue K562 1.64607 0.71902 0.00357 0.20269 DataSet_02_164
IFIT3 ZFX siRNA Prostate C4-2B 1.80952 0.85561 0.02693 0.06538 DataSet_02_172
IFIT3 CHD2 siRNA Haematopoietic_and_lymphoid_tissue K562 0.57306 -0.80324 0.00498 0.12618 DataSet_02_196
IFIT3 UBTF siRNA Haematopoietic_and_lymphoid_tissue K562 1.61538 0.69188 0.10172 1 DataSet_02_198
IFIT3 TAL1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.82677 0.8693 0.18755 1 DataSet_02_201
IFIT3 ZFX siRNA Mammary_gland MCF7 2 1 0.07637 0.25315 DataSet_02_206
IFIT3 ABL1 siRNA Mammary_gland MCF7 0.598607 -0.740319 0.451152822688292 0.976385569407162 DataSet_03_001
IFIT3 AR siRNA Prostate LNCaP 2.50686 1.32588 0.165173789344371 1 DataSet_03_005
IFIT3 BCL6 siRNA Mammary_gland MCF7 6.39193 2.67625 0.0250823929994273 0.989541443114508 DataSet_03_024
IFIT3 BCL6 siRNA Lymph OCI-Ly7 DLBCL 1.77894 0.831021 0.00141999679697398 0.342471156812105 DataSet_03_025
IFIT3 BCL6 siRNA Lymph Pfeiffer DLBCL 0.636647 -0.651434 0.0449947561452547 0.475412524254065 DataSet_03_026
IFIT3 BRCA1 siRNA Mammary_gland MCF7 0.343065 -1.54345 0.141977379640982 0.999850583334387 DataSet_03_028
IFIT3 CEBPA siRNA Mammary_gland MCF7 2.3182 1.21301 0.233584930501727 0.999962793175751 DataSet_03_047
IFIT3 CEBPB siRNA Embryo hESC 0.433554 -1.20572 0.0383191375020551 0.33526301639438 DataSet_03_049
IFIT3 CENPF siRNA Mammary_gland MCF7 3.49051 1.80344 0.0950556695090564 0.999662524742916 DataSet_03_052
IFIT3 CHEK1 siRNA Mammary_gland MCF7 2.03458 1.02473 0.306624042615105 0.999587656258211 DataSet_03_053
IFIT3 CTNNB1 siRNA Mammary_gland MCF7 4.37632 2.12972 0.0573720007196852 0.999436862066063 DataSet_03_058
IFIT3 E2F1 siRNA Mammary_gland MCF7 3.67876 1.87922 0.0845222995773814 0.999927373439084 DataSet_03_061
IFIT3 E2F5 siRNA Mammary_gland MCF7 3.09585 1.63033 0.124226215718533 0.999540347732068 DataSet_03_062
IFIT3 E2F7 siRNA Upper_aerodigestive_tract SCC25 2.78015 1.47516 5.86017368016838e-09 1.93406440746002e-06 DataSet_03_063
IFIT3 ERF siRNA Mammary_gland MCF7 1.50731 0.591975 0.5435191782168 0.999855523449227 DataSet_03_067
IFIT3 ESRRA siRNA Mammary_gland MCF7 0.477718 -1.06577 0.289244037513285 0.999964003642835 DataSet_03_072
IFIT3 FOXA1 siRNA Mammary_gland MCF7 0.455229 -1.13533 1.14585355167507e-05 0.000171639933311952 DataSet_03_081
IFIT3 FOXA1 siRNA Mammary_gland MCF7 0.455229 -1.13533 1.14585355167507e-05 0.000171639933311952 DataSet_03_082
IFIT3 FOXM1 siRNA Aorta Vascular smooth muscle cells 1.56927 0.650092 - - DataSet_03_090
IFIT3 FOXO1 shRNA Haematopoietic_and_lymphoid_tissue Namalwa 2.41651 1.27293 0.00143995258340077 0.0907053374630319 DataSet_03_095
IFIT3 FOXO1 siRNA Skin primary human dermal lymphatic endothelial cells 0.410253 -1.28541 - - DataSet_03_096
IFIT3 GATA3 siRNA Mammary_gland MCF7 1.99104 0.993526 0.320410529085208 0.999831535534034 DataSet_03_102
IFIT3 GATA4 siRNA Stomach AGS 1.75839 0.814256 0.000472598044602289 0.241208241053736 DataSet_03_105
IFIT3 GATA6 siRNA Stomach AGS 2.41873 1.27425 7.18382760184226e-05 0.0501825118444819 DataSet_03_108
IFIT3 GFP siRNA Upper_aerodigestive_tract SCC25 1.98979 0.99262 1.05601073824191e-05 0.000443960772091982 DataSet_03_112
IFIT3 GRHL3 siRNA Skin Primary neonatal keratinocytes 0.655325 -0.609718 0.304087184212106 0.550346327258235 DataSet_03_113
IFIT3 HDAC3 siRNA Mammary_gland MCF7 7.41899 2.89122 0.018312815224262 0.99997791025972 DataSet_03_114
IFIT3 HDAC5 siRNA Mammary_gland MCF7 3.63059 1.8602 0.0870504638917086 0.999966625300244 DataSet_03_115
IFIT3 HES6 siRNA Brain A172 0.45459 -1.13736 3.4321571731183e-05 0.0682854765569568 DataSet_03_116
IFIT3 HES6 siRNA Brain LN405 0.564537 -0.824859 0.00873429876941601 0.959972868676594 DataSet_03_117
IFIT3 HIC1 CRISPR Prostate PC3 1.86235 0.897128 - - DataSet_03_118
IFIT3 HIF1A siRNA Mammary_gland MCF7 2.84105 1.50642 0.15025663518973 0.999966843283762 DataSet_03_119
IFIT3 HINFP siRNA Bone_marrow hTERT-RPE1 1.63467 0.708997 0.000775568720965823 0.0670083733843329 DataSet_03_122
IFIT3 HMGA2 siRNA Mammary_gland MDA-MB-231 1.66967 0.739559 0.0234204180853044 0.684339964316225 DataSet_03_125
IFIT3 HNF4a siRNA Liver HepG2 0.628205 -0.670692 0.0363685873751791 0.611288534863205 DataSet_03_126
IFIT3 HOXB7 siRNA Mammary_gland MCF7 0.550512 -0.861154 0.38451012082309 0.999977683706165 DataSet_03_127
IFIT3 HSF2 siRNA Mammary_gland MCF7 2.36259 1.24037 0.224340855533729 0.990969613280381 DataSet_03_130
IFIT3 ID1 siRNA Mammary_gland MCF7 0.574463 -0.799715 0.417418771668132 0.999926480273844 DataSet_03_133
IFIT3 IRF4 siRNA Skin Cutaneous T cell lymphoma HuT-102 cells 2.27969 1.18884 0.0174883735841871 0.652519368107949 DataSet_03_134
IFIT3 JUND siRNA Mammary_gland MCF7 0.567629 -0.816979 0.89339982783091 0.999848956486105 DataSet_03_145
IFIT3 Klf4 siRNA Skin Primary neonatal keratinocytes 2.24674 1.16783 0.00558642929997832 0.0290314678404201 DataSet_03_147
IFIT3 KLF5 siRNA Stomach AGS 2.06605 1.04687 0.000168736340215883 0.0629997490926714 DataSet_03_149
IFIT3 KLF5 siRNA Stomach KatoIII 1.67365 0.742995 0.00511796848159093 0.201660926910527 DataSet_03_150
IFIT3 MAFB siRNA Peripheral_blood Monocyte-derived M-CSF macrophages 0.569066 -0.813333 0.52339928523026 1 DataSet_03_155
IFIT3 MEF2D shRNA Liver HuH7 1.59077 0.669725 - - DataSet_03_162
IFIT3 MITF siRNA Skin MZ7 1.71988 0.782305 0.000252223660354895 0.00204789320672893 DataSet_03_165
IFIT3 MITF siRNA Skin SK-MEL-5 0.515195 -0.95681 3.05278040708513e-05 0.000219043320618395 DataSet_03_168
IFIT3 MYC siRNA Colon HT29 2.82671 1.49912 - - DataSet_03_177
IFIT3 MYC siRNA Central_nervous_system DAOY M2.1 1.82007 0.863993 1.41449067820841e-06 1.05313045315776e-05 DataSet_03_178
IFIT3 MYCN siRNA Brain BE(2)C cells 1.67981 0.7483 - - DataSet_03_187
IFIT3 NCOR2 siRNA Mammary_gland MCF7 0.629297 -0.668186 0.494639567660427 0.999834929103349 DataSet_03_193
IFIT3 NMI siRNA Mammary_gland MCF7 0.623747 -0.680968 0.486734522124627 0.875523425203708 DataSet_03_199
IFIT3 NR4A3 siRNA Pancreas 1.1B4 1.67793 0.74668 1.08953894406011e-05 0.000159946236880437 DataSet_03_203
IFIT3 PAX3 siRNA Mammary_gland MCF7 0.653975 -0.612692 0.417956278303502 0.922311915825255 DataSet_03_206
IFIT3 PBX1 siRNA Mammary_gland LTED 2.47179 1.30556 0.00114829062562983 0.903026187000988 DataSet_03_208
IFIT3 PCNA siRNA Mammary_gland MCF7 4.63894 2.21379 0.0504137060552823 0.999448838103647 DataSet_03_210
IFIT3 PHB shRNA Embryo Embryonic stem cells (ESCs) 1.91309 0.935902 0.000964303660282672 0.00549885029019057 DataSet_03_211
IFIT3 PRRX1 siRNA Skin Fibroblast 1.58633 0.665698 0.00591352443844044 0.214656428766147 DataSet_03_216
IFIT3 PRRX1 CRISPR Neuroblastoma 691-MES 1.57669 0.656895 0.0941052005091117 0.89189998148014 DataSet_03_217
IFIT3 RARA siRNA Mammary_gland MCF7 0.476965 -1.06804 1.56782064941653e-05 0.00206507054534983 DataSet_03_218
IFIT3 RB1 siRNA Mammary_gland MCF7 3.15697 1.65854 0.118938259034113 0.999890290262508 DataSet_03_219
IFIT3 RBL2 siRNA Mammary_gland MCF7 14.9299 3.90014 0.00464821753489353 0.999927471951507 DataSet_03_220
IFIT3 RELA siRNA Fibroblasts WI38 0.455673 -1.13393 1.45659742480532e-06 0.000201653810388317 DataSet_03_222
IFIT3 RELA siRNA Fibroblasts WI38 0.501239 -0.996429 6.91723977015356e-07 4.26455209825914e-05 DataSet_03_223
IFIT3 RELB siRNA Pancreas MIA PaCa-2 2.85708 1.51454 3.80618562105499e-05 0.00924909030783266 DataSet_03_225
IFIT3 SOX11 siRNA Lung_fibroblast NHLF 1.83824 0.878322 0.0157512815631967 0.314096769871352 DataSet_03_237
IFIT3 SOX11 siRNA Lung_fibroblast NHLF 2.16802 1.11637 0.113105339021236 0.465010580956938 DataSet_03_238
IFIT3 SOX2 siRNA Mammary_gland GSC-11 0.604298 -0.726667 0.411249602083383 0.650560337031289 DataSet_03_245
IFIT3 SP1 siRNA Cervix HeLa 2.13061 1.09126 4.44125940593392e-07 0.000100182783786978 DataSet_03_249
IFIT3 SP1 siRNA Mammary_gland MDA-MB-231 1.81966 0.863671 4.69283150229258e-05 0.131130360428994 DataSet_03_250
IFIT3 SP1 siRNA Ovary OVSAYO 2.00004 1.00003 0.0895316029754234 0.365805272170327 DataSet_03_251
IFIT3 SP100 siRNA Mammary_gland MCF7 0.462384 -1.11284 0.270332811539757 0.999952086018951 DataSet_03_252
IFIT3 STAT1 knockout Liver Huh-7.5 0.474224 -1.07636 0.573918204704137 0.831594858107827 DataSet_03_257
IFIT3 STAT3 CRISPR Embryo hESC 1.98628 0.990072 0.0547865466435019 0.13054889743165 DataSet_03_258
IFIT3 STAT5B siRNA Mammary_gland MCF7 3.44926 1.78629 0.0976154887695478 0.999932708473107 DataSet_03_263
IFIT3 TCEA1 siRNA Mammary_gland MCF7 5.65379 2.49922 0.032665553412535 0.999762252994287 DataSet_03_266
IFIT3 TFAP2C siRNA Mammary_gland MCF7 53.103 5.73072 0.00010453053035786 0.155242545857633 DataSet_03_274
IFIT3 TP53 siRNA Mammary_gland MCF7 3.60832 1.85133 0.0882564317662273 0.999938217444253 DataSet_03_277
IFIT3 TP63 siRNA Skin Primary neonatal keratinocytes 6.87967 2.78234 4.77247712455565e-06 0.000998104114597337 DataSet_03_281
IFIT3 ZNF750 siRNA Skin Primary neonatal keratinocytes 2.2436 1.16582 0.00138937897474925 0.0348632696386965 DataSet_03_294
IFIT3 FUBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.82609 1.49881 0.00182343751409833 0.0558885446698448 DataSet_04_010
IFIT3 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 6.79888 2.7653 0.318867628262626 0.46766533489273 DataSet_04_014
IFIT3 ZNF574 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.226519 -2.14229 0.037065889240158 0.153330910529282 DataSet_04_023
IFIT3 SMAD2 CRISPR Liver HepG2 1.58511 0.66458 0.00517290693950821 0.488156813010195 DataSet_04_034
IFIT3 DDX20 CRISPR Liver HepG2 1.57396 0.654403 0.00338326653156945 0.0481489153018846 DataSet_04_043
IFIT3 CHCHD3 CRISPR Liver HepG2 2.43262 1.28251 0.012081202753842 0.462359872902174 DataSet_04_067
IFIT3 CALR shRNA Liver HepG2 0.621053 -0.687213 0.0172742745934355 0.0532464858997303 DataSet_04_053
IFIT3 CCAR1 shRNA Liver HepG2 4.78736 2.25923 0.0001109612585087 0.00860913704335324 DataSet_04_054
IFIT3 CNOT7 shRNA Liver HepG2 2.42647 1.27886 0.0075166209801524 0.023661296384052 DataSet_04_051
IFIT3 PRPF6 shRNA Liver HepG2 1.65482 0.726676 0.0143204494808004 0.0900195492787725 DataSet_04_056
IFIT3 YBX3 shRNA Liver HepG2 0.550847 -0.860275 0.0368925935826693 0.142018030685812 DataSet_02_98
IFIT3 SNW1 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.65421 1.40828 0.00549915800203505 0.0312893242163206 DataSet_04_049
IFIT3 DPF2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.457399 -1.12847 0.00670189602074095 0.0288674423549808 DataSet_02_14
IFIT3 ERF CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.473094 -1.0798 0.0115612489577163 0.0496529279485459 DataSet_02_34
IFIT3 HMGN3 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.607623 -0.718751 0.10270894184347 0.584876128485685 DataSet_02_45
IFIT3 NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.61435 -0.702868 0.103764721127905 0.419049965167568 DataSet_02_32
IFIT3 ABT1 shRNA Haematopoietic_and_lymphoid_tissue K562 4.08696 2.03103 0.000127090834721901 0.0130368318965116 DataSet_04_060
IFIT3 CNOT7 shRNA Haematopoietic_and_lymphoid_tissue K562 4.39623 2.13627 0.00179008056800535 0.0483130297745383 DataSet_04_061
IFIT3 DDX1 shRNA Haematopoietic_and_lymphoid_tissue K562 2 1 0.0912423630304409 0.551406302021682 DataSet_04_063
IFIT3 UBE2L3 shRNA Haematopoietic_and_lymphoid_tissue K562 1.63043 0.705257 0.00618608800246614 0.100127035013368 DataSet_04_062
IFIT3 EZH2 shRNA Colon SW480 2.65149 1.40681 - - DataSet_03_298
IFIT3 DNMT1 siRNA Lung_fibroblast IMR-90 1.80835 0.854677 2.250224e-01 0.9999458 DataSet_03_317
IFIT3 EZH2 knockdown Uterus Ishikawa (ISK) cell 1.89212 0.92 - - DataSet_03_324
IFIT3 SMARCA4 siRNA Colon HCT116 0.294755 -1.76241 4.979117e-03 0.1301247 DataSet_03_302
IFIT3 HDAC4 siRNA Liver human hepatocytes 0.647673 -0.626662 2.750284e-05 2.555875e-03 DataSet_03_345
IFIT3 ACTR5 siRNA Muscle RD 0.409973 -1.2864 - - DataSet_03_343
IFIT3 EZH2 siRNA Prostate LNCaP 0.421023 -1.24803 0.0372331854 0.9997152 DataSet_03_328
IFIT3 EZH2 siRNA Prostate LNCaP 0.421023 -1.24803 0.0372331854 0.9997152 DataSet_03_330
IFIT3 EZH2 shRNA Mammary_gland MCF7 9.35219 3.22531 7.124548e-13 4.463672e-09 DataSet_03_331
IFIT3 EZH2 knockdown Colon HCT116 2.96525 1.56816 0.108974234 0.8488990 DataSet_03_334
IFIT3 ARID3B CRISPR Colon HCT15 0.349532 -1.51651 - - DataSet_03_335
IFIT3 ZFX siRNA Prostate C4-2B 1.94086 0.956696 6.811049e-03 1.583644e-02 DataSet_03_348
IFIT3 ZFX siRNA Mammary_gland MCF7 1.96559 0.974962 2.594152e-02 1.128910e-01 DataSet_03_349
IFIT3 EZH2 shRNA Mammary_gland LM2 0.61801 -0.694298 1.639297e-05 1.177802e-02 DataSet_03_350
IFIT3 ESR1 siRNA Mammary_gland MCF7 1.64565 0.718655 4.904214e-02 0.1848631741 DataSet_03_352
IFIT3 ETV5 knockdown Colon HT29 0.186769 -2.42067 1.010802e-03 0.045748566 DataSet_03_353
IFIT3 TET1 CRISPR Mammary_gland Hs578T 4.13595 2.04822 3.660509e-05 2.755061e-03 DataSet_03_355
IFIT3 CREBBP CRISPR Brain U5-NPC 1.57377 0.654225 0.5615597363 0.7615550 DataSet_03_356
IFIT3 PTPN14 CRISPR Brain U5-NPC 1.7675 0.821714 1.227561e-01 0.35014388 DataSet_03_357
IFIT3 TP53 CRISPR Brain U5-NPC 5.79157 2.53395 9.495302e-04 1.623145e-01 DataSet_03_358
IFIT3 ZNF148 shRNA Mammary_gland MDA-MB-231 3.39215 1.7622 5.855190e-03 0.056065181 DataSet_03_366
IFIT3 ZFP36L1 siRNA Urinary_bladder J82 4.34021 2.11776 - - DataSet_03_371
IFIT3 BHLHE40 shRNA Cervix HeLaS3 15.5957 3.96308 5.210285e-01 0.91201136 DataSet_03_372
IFIT3 ZNF213 siRNA Mammary_gland MCF7 2.47196 1.30566 6.566377e-01 8.372674e-01 DataSet_03_376
IFIT3 SMARCA2 shRNA Lung NCI-H1944 0.624035 -0.680301 1.267178e-02 2.421027e-01 DataSet_03_377
IFIT3 DDX5 shRNA Stomach HGC-27 0.410256 -1.2854 - - DataSet_03_379
IFIT3 ZBTB7A siRNA Stomach BGC823 0.425524 -1.23269 - - DataSet_03_380
IFIT3 DNMT1 siRNA Skin Human melanoma cells 1.66353 0.734251 8.533219e-06 9.485962e-05 DataSet_03_382
IFIT3 TCF19 CRISPR Oral_squamous CAL27 1.60247 0.680293 2.365772e-02 0.1315247433 DataSet_03_383
IFIT3 YY1 shRNA Brain GSC1517 3.33816 1.73905 - - DataSet_03_384
IFIT3 YY1 shRNA Brain GSC3028 2.16703 1.11572 - - DataSet_03_386
IFIT3 KAT6A CRISPR Haematopoietic_and_lymphoid_tissue MOLM-13 3.75447 1.90861 0.1998854068 0.8388073 DataSet_03_387
IFIT3 TRIM8 siRNA Mammary_gland MCF7 32.6492 5.02898 1.510136e-02 0.0688067438 DataSet_03_388
IFIT3 ASXL1 CRISPR Embryo iPSC 0.608261 -0.717238 0.2062539601 0.8187866 DataSet_03_394
IFIT3 JAZF1 siRNA Cervix HeLa Kyoto 0.571816 -0.806378 7.124118e-03 0.437508478 DataSet_03_396
IFIT3 RELA CRISPR Brain T30 1.59679 0.675176 0.3792208187 0.8400824 DataSet_03_399
IFIT3 HMGA1 shRNA Bile_duct HUCCT1 2.44697 1.291 1.818117e-03 0.050836921 DataSet_03_400
IFIT3 EHF shRNA Stomach MKN7 6.91639 2.79002 - - DataSet_03_402
IFIT3 JARID2 siRNA Adipose_tissue human adipose tissue derived stem cells 1.55494 0.63686 1.038578e-02 0.3239928 DataSet_03_403
IFIT3 TFAP2A knockout Embryo H9 4.85714 2.28011 9.916759e-03 0.06477231 DataSet_03_405
IFIT3 USP22 shRNA Liver HuH7 13.3433 3.73805 - - DataSet_03_411
IFIT3 E2F1 siRNA Prostate LNCaP 3.06667 1.61667 2.918355e-06 0.0073603574 DataSet_03_413
IFIT3 E2F2 siRNA Prostate LNCaP 4.51333 2.17419 6.443200e-08 1.068586e-04 DataSet_03_414
IFIT3 ZKSCAN3 CRISPR Colon HCT116 0.238494 -2.06798 1.452667e-03 0.092301465 DataSet_03_415
IFIT3 RUNX2 shRNA Cord_blood Natural Killer Cell 0.395143 -1.33955 1.050505e-01 0.793390621 DataSet_03_416
IFIT3 NFATC2 shRNA Haematopoietic_and_lymphoid_tissue THP-1 1.99275 0.994763 2.660660e-02 0.107666819 DataSet_03_418
IFIT3 PRDM1 CRISPR Lymph CD8+ T cells 11.3707 3.50726 - - DataSet_03_421
IFIT3 FOXQ1 CRISPR Lymph Primary CD4+ T cells 1.68605 0.753644 - - DataSet_03_422
IFIT3 MAEL CRISPR Liver Alexander cells 0.432432 -1.20945 - - DataSet_03_423
IFIT3 FOXP3 CRISPR Peripheral_blood Naive Treg 2.06743 1.04784 2.392742e-01 0.594905086 DataSet_03_427
IFIT3 IKZF2 shRNA Lymph Hut78 2.1703 1.11789 3.639730e-02 0.43145201 DataSet_03_429
IFIT3 USP7 shRNA Skin xenograft cells 0.408343 -1.29215 0.26787056 0.4348960 DataSet_03_431
IFIT3 PLAG1 shRNA Cord_blood Lin-CD34+ HSPCs 0.463696 -1.10875 - - DataSet_03_432
IFIT3 POU2AF1 CRISPR Haematopoietic_and_lymphoid_tissue OCI-Ly7 3.56372 1.83338 3.484955e-04 0.076768042 DataSet_03_434
IFIT3 POU2AF1 CRISPR Lymph SUDHL4 213.897 7.74077 3.695704e-04 0.008971682 DataSet_03_435
IFIT3 SUFU shRNA Mammary_gland HCC1954 cells 0.547619 -0.868755 0.0324948620 0.4392140 DataSet_03_437
IFIT3 FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 1.59429 0.67291 3.047143e-01 0.90558273 DataSet_03_439
IFIT3 SETDB1 shRNA Colon HCT116 1.5984 0.676633 - - DataSet_03_440
IFIT3 CAMTA1 knockout Embryo_kidney HEK293T 3.2 1.67807 1.831602e-01 0.38241787 DataSet_03_448
IFIT3 RELB CRISPR Colon SW480 1.59519 0.673729 4.807088e-03 5.210346e-02 DataSet_03_449
IFIT3 CBX2 siRNA Mammary_gland MDA-MB-231 0.395551 -1.33806 2.116900e-03 1.546691e-02 DataSet_03_450
IFIT3 CBX2 siRNA Mammary_gland MCF7 2.23568 1.16071 8.078611e-01 0.8862257948 DataSet_03_451
IFIT3 OGT siRNA Embryo BeWo cells 2.4 1.26303 4.743012e-02 0.55837810 DataSet_03_453
IFIT3 SMARCA2 shRNA Lung HCC2302 0.47762 -1.06606 5.082630e-10 3.315955e-09 DataSet_03_455
IFIT3 SREBF2 siRNA Umbilical_vein HUVEC 4.31031 2.10779 1.238951e-01 5.379037e-01 DataSet_03_457
IFIT3 ARID1A shRNA Bile_duct MMNK1 5.33309 2.41497 1.116170e-04 0.011522039 DataSet_03_458
IFIT3 TXNIP shRNA Cord_Blood CD34+ cells 1.91933 0.9406 - - DataSet_03_461
IFIT3 TXNIP shRNA Cord_blood ST3 2.25624 1.17392 8.848956e-03 0.1460198401 DataSet_03_462
IFIT3 SOX9 knockout Liver HuH7 1.6828 0.75086 1.357462e-02 5.374846e-02 DataSet_03_463
IFIT3 SMARCA1 Cas13 Embryo_kidney HEK293T 0.391304 -1.35364 - - DataSet_03_466
IFIT3 LIN28A siRNA Mammary_gland MCF7M 4.78708 2.25915 1.443843e-03 0.1499769 DataSet_03_469
IFIT3 LIN28A siRNA Mammary_gland MCF7M 4.78708 2.25915 1.443843e-03 0.1499769 DataSet_03_470
IFIT3 WHSC1 siRNA Prostate PC3 0.518708 -0.947004 2.122150e-03 0.07761533 DataSet_03_471
Regulation Region
 
T(co)Fs that significantly regulate SP100 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of IFIT3
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines