Gene Overview
Target Gene: CAV1
NCBI Official Symbol: CAV1
Entrez ID: 857
Ensembl ID: ENSG00000105974
Gene Full Name: caveolin 1
Strand: +
Gene Locus: 7q31.2
External Links:

CAV1 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate CAV1   
T(co)Fs that Repress CAV1
The Intensity of the Gene Regulated by T(co)Fs:
CAV1-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
CAV1 HNF1B shRNA Ovary RMG2 0.40994 -1.28653 0.06232 0.11044 DataSet_01_103
CAV1 SPDEF shRNA Mammary_gland MCF7 0.27152 -1.8809 0.42568 0.99999 DataSet_01_107
CAV1 ESR1 siRNA Mammary_gland MCF7 0.60903 -0.71541 6.96505e-06 0.00275 DataSet_01_111
CAV1 TCF3 shRNA Mammary_gland MDA-MB468 1.62064 0.69656 3.8751e-07 4.8209e-05 DataSet_01_116
CAV1 GATA3 siRNA Mammary_gland MCF7 0.30647 -1.70617 1.0431e-07 3.47789e-05 DataSet_01_120
CAV1 ZIC2 siRNA Pancreas PANC1 1.77313 0.8263 - - DataSet_01_121
CAV1 FOXM1 siRNA Central_nervous_system U87 9.36778 3.22771 - - DataSet_01_122
CAV1 ZNF91 siRNA Gastrointestinal_tissue GIST-T1 0.51984 -0.94385 2.13776e-05 0.00224 DataSet_01_123
CAV1 ZNF100 siRNA Gastrointestinal_tissue GIST-T1 0.41973 -1.25246 1.96427e-06 0.00097 DataSet_01_124
CAV1 ZNF43 siRNA Gastrointestinal_tissue GIST-T1 0.37602 -1.41112 6.94641e-07 0.00083 DataSet_01_125
CAV1 ZNF85 siRNA Gastrointestinal_tissue GIST-T1 0.58532 -0.77271 0.00011 0.00326 DataSet_01_126
CAV1 ZNF254 siRNA Gastrointestinal_tissue GIST-T1 0.35335 -1.50085 4.03538e-07 0.00018 DataSet_01_127
CAV1 ZNF708 siRNA Gastrointestinal_tissue GIST-T1 0.53974 -0.88965 3.4594e-05 0.00269 DataSet_01_130
CAV1 NFYA shRNA Cervix HeLaS3 0.61302 -0.706 0.00119 0.02024 DataSet_01_131
CAV1 ID1 shRNA Neuroepithelium GSC2 2.73141 1.44964 1.03418e-13 1.5436e-11 DataSet_01_133
CAV1 ID1 shRNA Neuroepithelium GSC8 0.19025 -2.39405 4.36736e-16 1.46671e-13 DataSet_01_134
CAV1 SPDEF shRNA Mammary_gland MCF7 1.55341 0.63544 0.02425 0.26046 DataSet_01_135
CAV1 IKZF2 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 2.66834 1.41594 0.00795 0.2687 DataSet_01_137
CAV1 IKZF1 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 4.85999 2.28095 7.36979e-05 0.06005 DataSet_01_138
CAV1 TFAP2C shRNA Mammary_gland MCF7 3.06613 1.61642 6.46988e-11 1.76037e-09 DataSet_01_150
CAV1 ELK1 siRNA Peripheral_blood CD4+ T cells 0.30898 -1.6944 0.00381 0.02714 DataSet_01_162
CAV1 GATA3 siRNA Peripheral_blood CD4+ T cells 2.2596 1.17607 0.0084 0.17495 DataSet_01_163
CAV1 JUN siRNA Peripheral_blood CD4+ T cells 0.26923 -1.89306 0.00175 0.02228 DataSet_01_164
CAV1 MAF siRNA Peripheral_blood CD4+ T cells 0.35466 -1.4955 0.00865 0.09645 DataSet_01_165
CAV1 NFATC3 siRNA Peripheral_blood CD4+ T cells 0.38176 -1.38925 0.01498 0.11484 DataSet_01_166
CAV1 NFKB1 siRNA Peripheral_blood CD4+ T cells 2.00351 1.00253 0.02763 0.44682 DataSet_01_167
CAV1 STAT3 siRNA Peripheral_blood CD4+ T cells 0.49771 -1.00661 0.07056 0.99183 DataSet_01_168
CAV1 NR5A2 siRNA Mammary_gland MCF7 0.60207 -0.73201 8.1202e-06 0.00062 DataSet_01_182
CAV1 TP63 shRNA Bladder UC14 0.24132 -2.05096 2.44963e-09 1.17472e-06 DataSet_01_183
CAV1 SPDEF siRNA Mammary_gland MCF7 0.4877 -1.03593 7.07727e-05 0.03841 DataSet_01_189
CAV1 GABPA shRNA Prostate C4-2B 2232.81 11.1247 0.23761 0.43934 DataSet_01_190
CAV1 GABPA shRNA Prostate LNCaP 1348.07 10.3967 0.46154 0.7048 DataSet_01_191
CAV1 HIC1 shRNA Mammary_gland HBL100 0.65489 -0.61068 - - DataSet_01_205
CAV1 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly10 0.6505 -0.62038 - - DataSet_01_208
CAV1 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 0.3856 -1.37484 - - DataSet_01_209
CAV1 LIN28A siRNA Embryo H9 22.8125 4.51175 6.557e-08 0.00013 DataSet_01_215
CAV1 TAL1 shRNA Haematopoietic_and_lymphoid_tissue HEL 2.84744 1.50967 1.74094e-05 0.00343 DataSet_01_217
CAV1 KLF9 siRNA Liver HepG2 1.69278 0.7594 2.10928e-05 3e-04 DataSet_01_222
CAV1 FOXM1 siRNA Mammary_gland MCF7 0.61583 -0.69939 0.06102 0.61807 DataSet_01_223
CAV1 SNAI2 shRNA Skin Primary human keratinocytes 0.64027 -0.64326 0.0011 0.01538 DataSet_01_225
CAV1 ARNT shRNA Embryo hESC HSF1 0.64043 -0.64289 0.25633 0.99999 DataSet_01_240
CAV1 TWIST1 shRNA Stomach CAF32 0.42348 -1.23964 0.00164 0.02299 DataSet_01_253
CAV1 TWIST1 shRNA Stomach CAF 0.58432 -0.77517 0.14142 0.62661 DataSet_01_254
CAV1 MYT1L shRNA Fetal_spinal_cord SPC04 1.7551 0.81155 0.02252 0.24406 DataSet_01_264
CAV1 SIX4 siRNA Ovary PEO1 1.72942 0.79029 0.00151 0.01925 DataSet_01_269
CAV1 SALL4 shRNA Lung H661 0.45757 -1.12794 0.00221 0.06053 DataSet_01_277
CAV1 ZIC5 siRNA Skin A375 0.44553 -1.16639 - - DataSet_01_284
CAV1 TP53 shRNA Haematopoietic_and_lymphoid_tissue JVM2 0.58982 -0.76166 3.84669e-05 0.00056 DataSet_01_286
CAV1 NFYA shRNA Lung H322 0.6333 -0.65903 8.77333e-05 0.00159 DataSet_01_288
CAV1 SP3 siRNA Haematopoietic_and_lymphoid_tissue JURKAT 3.22775 1.69053 0.00408 0.77909 DataSet_01_290
CAV1 SNAI2 siRNA Mammary_gland MCFDCIS 0.53564 -0.90066 0.01448 0.46133 DataSet_01_292
CAV1 POSTN shRNA Brain GSC272 0.33447 -1.58005 0.04025 0.53146 DataSet_01_293
CAV1 TFAP4 siRNA Brain BE(2)-C 0.25759 -1.95685 0.40839 0.51625 DataSet_01_295
CAV1 PTEN shRNA Mammary_gland SKBR3 0.64064 -0.64242 0.04442 0.561 DataSet_01_303
CAV1 BRD4 siRNA Ovary Ovcar8 0.32853 -1.60592 1.62137e-06 3e-04 DataSet_01_311
CAV1 RUNX1 shRNA Embryo H9 0.52242 -0.93672 0.30322 0.529 DataSet_01_314
CAV1 ARNT siRNA Upper_aerodigestive_tract HSC3 4898.32 12.2581 - - DataSet_01_315
CAV1 ARNT shRNA Placenta_tissue CTB 0.35736 -1.48456 0.00011 0.0074 DataSet_01_317
CAV1 ELK3 shRNA Mammary_gland MDA-MB-231 0.11668 -3.09941 7.22971e-08 9.50653e-06 DataSet_01_318
CAV1 MYC siRNA Colon HCT116 1.73245 0.79282 1.99292e-09 5.9371e-08 DataSet_01_324
CAV1 TP63 shRNA Head_and_neck FaDU 0.61278 -0.70656 3.2645e-06 0.00028 DataSet_01_327
CAV1 TP63 shRNA Head_and_neck FaDU 0.61278 -0.70656 3.2645e-06 0.00028 DataSet_01_330
CAV1 HIF1A siRNA Oral_cavity OEC-M1 0.60682 -0.72066 0.09405 0.85151 DataSet_01_348
CAV1 SOX2 shRNA Neuroepithelium HF2303 0.48287 -1.0503 0.0532 1 DataSet_01_349
CAV1 ETV4 shRNA Prostate PC3 0.4649 -1.10499 - - DataSet_01_356
CAV1 CDX2 siRNA Colon COLO320 0.3418 -1.54877 - - DataSet_01_357
CAV1 GTF2B siRNA Cervix HeLa 0.60016 -0.73658 - - DataSet_01_362
CAV1 RBM17 shRNA Liver HepG2 1.51351 0.5979 0.40399 0.65739 DataSet_02_100
CAV1 SAFB2 shRNA Liver HepG2 0.26923 -1.89308 0.01883 0.05672 DataSet_02_102
CAV1 FIP1L1 shRNA Liver HepG2 0.49123 -1.02554 0.81767 0.86562 DataSet_02_103
CAV1 U2AF2 shRNA Liver HepG2 1.76923 0.82312 0.61826 0.73223 DataSet_02_105
CAV1 SSB shRNA Liver HepG2 0.27778 -1.848 0.91873 0.94054 DataSet_02_107
CAV1 ZNF622 shRNA Liver HepG2 3.30769 1.72583 0.07211 0.11886 DataSet_02_108
CAV1 HNRNPUL1 shRNA Liver HepG2 0.65385 -0.61298 0.35386 0.45131 DataSet_02_109
CAV1 BCLAF1 shRNA Liver HepG2 0.61111 -0.71049 0.10229 0.19552 DataSet_02_112
CAV1 U2AF2 shRNA Liver HepG2 1.89189 0.91983 0.67649 0.77599 DataSet_02_113
CAV1 XRCC5 shRNA Liver HepG2 0.38462 -1.37851 0.01198 0.14405 DataSet_02_114
CAV1 TARDBP shRNA Liver HepG2 0.625 -0.67807 0.61873 0.69767 DataSet_02_116
CAV1 RBM34 shRNA Liver HepG2 1.61538 0.69188 0.47988 0.74924 DataSet_02_121
CAV1 EWSR1 shRNA Liver HepG2 1.55556 0.63743 0.1022 0.20448 DataSet_02_122
CAV1 FUS shRNA Liver HepG2 3.69231 1.88452 0.05428 0.18167 DataSet_02_124
CAV1 HNRNPLL shRNA Liver HepG2 2.6875 1.42626 0.17461 0.24803 DataSet_02_125
CAV1 SNRNP70 shRNA Liver HepG2 1.625 0.70044 0.3752 0.49202 DataSet_02_126
CAV1 SRSF3 shRNA Liver HepG2 5 2.32193 0.06831 0.18557 DataSet_02_127
CAV1 TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 0.57812 -0.79055 0.32281 0.60364 DataSet_02_129
CAV1 SRSF7 shRNA Haematopoietic_and_lymphoid_tissue K562 0.23438 -2.09311 0.18411 0.42718 DataSet_02_133
CAV1 PCBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.65625 -0.60768 0.62244 0.78752 DataSet_02_137
CAV1 RBM17 shRNA Haematopoietic_and_lymphoid_tissue K562 2.04082 1.02915 0.13101 0.40491 DataSet_02_138
CAV1 RBFOX2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.38824 -1.365 0.00738 0.44546 DataSet_02_139
CAV1 TAF15 shRNA Haematopoietic_and_lymphoid_tissue K562 2.14545 1.10128 0.88406 0.94622 DataSet_02_140
CAV1 BCLAF1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.03659 1.02615 0.01286 0.11489 DataSet_02_142
CAV1 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 1.65957 0.73081 0.41559 0.50356 DataSet_02_143
CAV1 DROSHA shRNA Haematopoietic_and_lymphoid_tissue K562 3.40909 1.76939 0.00219 0.46951 DataSet_02_145
CAV1 CCAR2 shRNA Haematopoietic_and_lymphoid_tissue K562 2.27586 1.18641 0.12488 0.55125 DataSet_02_146
CAV1 NONO shRNA Haematopoietic_and_lymphoid_tissue K562 1.78947 0.83954 0.23412 0.43306 DataSet_02_149
CAV1 ILF2 shRNA Haematopoietic_and_lymphoid_tissue K562 2.20833 1.14296 0.03181 0.29002 DataSet_02_152
CAV1 HNRNPUL1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.68182 1.42321 0.00393 0.51515 DataSet_02_156
CAV1 PSIP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.41346 -1.27417 0.23768 0.36794 DataSet_02_158
CAV1 HNRNPL shRNA Haematopoietic_and_lymphoid_tissue K562 4.31818 2.11042 0.03504 0.16742 DataSet_02_160
CAV1 AGO1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.68675 0.75424 0.19504 0.6603 DataSet_02_162
CAV1 U2AF1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.38182 1.25206 0.29864 0.47426 DataSet_02_165
CAV1 EWSR1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.76471 0.81943 0.01887 0.22555 DataSet_02_167
CAV1 TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 1.86207 0.89691 0.4947 0.59119 DataSet_02_169
CAV1 U2AF2 shRNA Haematopoietic_and_lymphoid_tissue K562 3.29091 1.71849 0.00029 0.04371 DataSet_02_170
CAV1 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 2.18182 1.12553 0.01801 0.2135 DataSet_02_171
CAV1 LMNA siRNA Haematopoietic_and_lymphoid_tissue K562 3.51852 1.81497 0.45003 1 DataSet_02_175
CAV1 CEBPZ siRNA Haematopoietic_and_lymphoid_tissue K562 0.5098 -0.97199 0.99671 1 DataSet_02_176
CAV1 TBL1XR1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.46875 -1.09311 0.01316 1 DataSet_02_178
CAV1 ATF3 siRNA Haematopoietic_and_lymphoid_tissue K562 0.45946 -1.12199 0.09938 1 DataSet_02_180
CAV1 ZMIZ1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.57576 -0.79647 0.55235 1 DataSet_02_181
CAV1 MAFK siRNA Haematopoietic_and_lymphoid_tissue K562 2.5 1.32193 0.38862 1 DataSet_02_183
CAV1 KAT2B siRNA Haematopoietic_and_lymphoid_tissue K562 0.38272 -1.38565 0.02188 1 DataSet_02_184
CAV1 CTCF siRNA Haematopoietic_and_lymphoid_tissue K562 2.78788 1.47917 0.6723 1 DataSet_02_185
CAV1 BHLHE40 siRNA Haematopoietic_and_lymphoid_tissue K562 1.67105 0.74076 0.18535 1 DataSet_02_186
CAV1 CHD1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.91594 1 DataSet_02_187
CAV1 BACH1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.2451 -2.02857 0.59225 1 DataSet_02_188
CAV1 MAFG siRNA Haematopoietic_and_lymphoid_tissue K562 0.42157 -1.24616 0.9001 1 DataSet_02_189
CAV1 LMNB2 siRNA Haematopoietic_and_lymphoid_tissue K562 2.81481 1.49304 0.45301 1 DataSet_02_191
CAV1 ARID3A siRNA Haematopoietic_and_lymphoid_tissue K562 0.23699 -2.07708 0.01398 1 DataSet_02_193
CAV1 TCP1 siRNA Haematopoietic_and_lymphoid_tissue K562 4.88889 2.28951 0.25555 1 DataSet_02_194
CAV1 LMNB1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.51961 -0.9445 0.94793 1 DataSet_02_195
CAV1 CHD2 siRNA Haematopoietic_and_lymphoid_tissue K562 3.5 1.80735 0.03624 0.14583 DataSet_02_196
CAV1 MAZ siRNA Haematopoietic_and_lymphoid_tissue K562 0.43353 -1.20581 0.08427 1 DataSet_02_199
CAV1 E2F4 siRNA Haematopoietic_and_lymphoid_tissue K562 3.62963 1.85982 0.13594 1 DataSet_02_200
CAV1 TAL1 siRNA Haematopoietic_and_lymphoid_tissue K562 2.35 1.23266 0.03485 1 DataSet_02_201
CAV1 BRCA1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.37838 -1.4021 0.44411 1 DataSet_02_202
CAV1 ZNF384 siRNA Haematopoietic_and_lymphoid_tissue K562 0.34375 -1.54057 0.00637 1 DataSet_02_203
CAV1 RCOR1 siRNA Haematopoietic_and_lymphoid_tissue K562 2.03846 1.02748 0.38247 1 DataSet_02_204
CAV1 E2F6 siRNA Haematopoietic_and_lymphoid_tissue K562 0.30392 -1.71823 0.66374 1 DataSet_02_205
CAV1 ARID2 CRISPR Liver JHH4 0.59751 -0.742965 0.841201239271439 1 DataSet_03_015
CAV1 ASCL1 siRNA Lung DMS79 1.7 0.765535 0.966391069746264 0.992507227385187 DataSet_03_016
CAV1 ATF4 siRNA Skin A375 0.508734 -0.975018 0.0615784556513812 0.775512819201899 DataSet_03_018
CAV1 ATR siRNA Mammary_gland MCF7 0.635616 -0.653773 0.409006690766391 0.999819450785634 DataSet_03_020
CAV1 BCL6 siRNA Mammary_gland MCF7 0.583096 -0.778194 0.331048237882438 0.989541443114508 DataSet_03_024
CAV1 BCL6 siRNA Lymph Pfeiffer DLBCL 1.93449 0.951954 0.376037906507882 0.786163148318103 DataSet_03_026
CAV1 BRCA1 siRNA Mammary_gland MCF7 0.647886 -0.626187 0.4280274447317 0.999850583334387 DataSet_03_028
CAV1 CDK2 siRNA Mammary_gland MCF7 0.661238 -0.596759 0.449015594782943 0.99987175116756 DataSet_03_044
CAV1 CEBPA siRNA Mammary_gland MCF7 3.96167 1.98611 0.0338222246982924 0.999962793175751 DataSet_03_047
CAV1 CENPF siRNA Mammary_gland MCF7 1.92967 0.948355 0.244349313052593 0.999662524742916 DataSet_03_052
CAV1 CTNNB1 siRNA Mammary_gland MCF7 2.44341 1.2889 0.128794503331199 0.999436862066063 DataSet_03_058
CAV1 E2F1 siRNA Mammary_gland MCF7 1.84755 0.885613 0.273760841382186 0.999927373439084 DataSet_03_061
CAV1 E2F5 siRNA Mammary_gland MCF7 1.91514 0.93745 0.249255891951737 0.999540347732068 DataSet_03_062
CAV1 ERBB2 siRNA Mammary_gland MCF7 0.665193 -0.588155 0.455287545788187 0.998282799776643 DataSet_03_066
CAV1 ERF siRNA Mammary_gland MCF7 0.647676 -0.626655 0.427699817064569 0.999855523449227 DataSet_03_067
CAV1 ESR1 siRNA Mammary_gland MCF7 0.642608 -0.637988 0.285950057250946 0.999753934970283 DataSet_03_068
CAV1 ESR1 siRNA Mammary_gland MCF7 1.98662 0.990316 0.0044952946131881 0.0199788952107782 DataSet_03_071
CAV1 ESRRA siRNA Mammary_gland MCF7 0.592115 -0.756051 0.343994163864972 0.999964003642835 DataSet_03_072
CAV1 FHL2 siRNA Prostate LNCaP 1.72116 0.783378 0.0377578070345075 0.53183252591288 DataSet_03_076
CAV1 FOS siRNA Mammary_gland MCF7 0.637728 -0.648987 0.412261477184932 0.999966427400474 DataSet_03_079
CAV1 FOXA1 siRNA Mammary_gland MCF7 6.6423 2.73168 1.04101364102527e-08 3.06075654760429e-06 DataSet_03_080
CAV1 FOXA1 siRNA Mammary_gland MCF7 3.08147 1.62362 4.27079660940602e-14 1.07867229400487e-11 DataSet_03_081
CAV1 FOXA1 siRNA Mammary_gland MCF7 3.08147 1.62362 4.27079660940602e-14 1.07867229400487e-11 DataSet_03_082
CAV1 FOXP1 siRNA Mammary_gland MCF7 0.648411 -0.62502 0.428846310789411 0.999975993110711 DataSet_03_099
CAV1 GATA3 siRNA Mammary_gland MCF7 0.633191 -0.659288 0.405280227026473 0.999831535534034 DataSet_03_102
CAV1 GATA3 siRNA Mammary_gland MCF7 1.59829 0.67653 0.0202443091079797 0.126804732785688 DataSet_03_103
CAV1 GATA6 siRNA Stomach AGS 0.388941 -1.36238 0.00426336257245542 0.212237049440281 DataSet_03_108
CAV1 HDAC5 siRNA Mammary_gland MCF7 2.34354 1.22869 0.144529450962376 0.999966625300244 DataSet_03_115
CAV1 HIF1A siRNA Mammary_gland MCF7 0.573954 -0.800992 0.318132572241633 0.999966843283762 DataSet_03_119
CAV1 HINFP siRNA Bone_marrow U2OS 0.605368 -0.724115 0.000196677742437501 0.0141059945967261 DataSet_03_123
CAV1 HOXB7 siRNA Mammary_gland MCF7 0.575591 -0.796883 0.32042963260806 0.999977683706165 DataSet_03_127
CAV1 HSF2 siRNA Mammary_gland MCF7 2.10341 1.07273 0.194135980162835 0.990969613280381 DataSet_03_130
CAV1 HTATIP siRNA Prostate LNCaP 1.60558 0.683099 0.0391351800897944 0.059086448370866 DataSet_03_131
CAV1 ID1 siRNA Mammary_gland MCF7 0.632486 -0.660894 0.404199951767346 0.999926480273844 DataSet_03_133
CAV1 JUND siRNA Mammary_gland MCF7 0.662961 -0.593003 0.658714162573541 0.999848956486105 DataSet_03_145
CAV1 KDM3A siRNA Mammary_gland MCF7 2.5692 1.36132 7.23192878940006e-05 0.00342765761501975 DataSet_03_146
CAV1 Klf4 siRNA Skin Primary neonatal keratinocytes 2.77715 1.4736 1.54059808020976e-05 0.000829891826540857 DataSet_03_147
CAV1 KLF5 siRNA Stomach YCC3 0.523997 -0.932369 0.00145118494053083 0.0654696039316563 DataSet_03_151
CAV1 MAPK14 siRNA Mammary_gland MCF7 0.602555 -0.730834 0.492514638643824 0.999824418484635 DataSet_03_157
CAV1 MAX siRNA Mammary_gland MCF7 0.626967 -0.673538 0.395768407161273 0.999907009675999 DataSet_03_158
CAV1 MCM2 siRNA Mammary_gland MCF7 0.629166 -0.668487 0.399120703093058 0.999925560383539 DataSet_03_161
CAV1 MEF2D shRNA Liver HuH7 2.77486 1.47241 - - DataSet_03_162
CAV1 MEF2D siRNA Liver HuH7 0.546205 -0.872486 - - DataSet_03_163
CAV1 MITF siRNA Skin MZ7 1.54393 0.626607 1.76757111257598e-06 2.56157527901884e-05 DataSet_03_165
CAV1 MITF siRNA Skin Ma-Mel-15 1.72747 0.788658 0.0103203649985445 0.13939726648735 DataSet_03_167
CAV1 MTA2 siRNA Stomach SGC-7901 1.66477 0.735318 - - DataSet_03_169
CAV1 MYB siRNA Cord_Blood CD34+ progenitor cells 3.84567 1.94324 - - DataSet_03_170
CAV1 MYC siRNA Central_nervous_system DAOY M2.1 2.17566 1.12145 1.85296905210677e-08 5.84076343862766e-07 DataSet_03_178
CAV1 NCOR2 siRNA Mammary_gland MCF7 0.600945 -0.734696 0.356856361859994 0.999834929103349 DataSet_03_193
CAV1 NMI siRNA Mammary_gland MCF7 0.591243 -0.758176 0.342734413721975 0.830321011382357 DataSet_03_199
CAV1 NPAT siRNA Bone_marrow U2OS 0.603652 -0.728211 7.97660045940898e-05 0.00723721306651363 DataSet_03_201
CAV1 NR4A3 siRNA Pancreas 1.1B4 0.421737 -1.24558 5.07931443546565e-08 5.49555435868367e-06 DataSet_03_203
CAV1 PAX3 siRNA Mammary_gland MCF7 0.612619 -0.706938 0.257060408984828 0.919978041032696 DataSet_03_206
CAV1 PCNA siRNA Mammary_gland MCF7 1.80928 0.855418 0.288959271365317 0.999448838103647 DataSet_03_210
CAV1 PHB shRNA Embryo Embryonic stem cells (ESCs) 12.1362 3.60124 1.39926894084294e-07 8.92520379260888e-05 DataSet_03_211
CAV1 RB1 siRNA Mammary_gland MCF7 1.84493 0.883565 0.274769939820404 0.999890290262508 DataSet_03_219
CAV1 RELB siRNA Immortalized_keratinocyte HaCaT 58.566 5.87199 2.50585056308576e-12 1.57649893061624e-09 DataSet_03_227
CAV1 SOX11 siRNA Lung_fibroblast NHLF 0.56625 -0.820488 0.0062770858081131 0.304507242190339 DataSet_03_237
CAV1 SOX2 siRNA Lung LK2 0.486984 -1.03805 - - DataSet_03_241
CAV1 SOX9 knockdown Liver HepG2 1.51028 0.594813 3.74457834800948e-05 0.00169368790742985 DataSet_03_248
CAV1 SP1 siRNA Ovary OVSAYO 0.346316 -1.52984 0.0487587394824657 0.271402577801357 DataSet_03_251
CAV1 STAT1 siRNA Mammary_gland MCF7 0.657214 -0.605565 0.442659913720101 0.999890411872485 DataSet_03_256
CAV1 STAT3 CRISPR Embryo hESC 0.117772 -3.08593 0.00295267733416955 0.0391260289059535 DataSet_03_258
CAV1 STAT5B siRNA Mammary_gland MCF7 2.44322 1.28879 0.128822555743521 0.999932708473107 DataSet_03_263
CAV1 TP53 knockout Haematopoietic_and_lymphoid_tissue MOLP8 0.48882 -1.03262 0.0449266911545307 0.695067431188456 DataSet_03_280
CAV1 WT1 siRNA Mammary_gland MCF7 0.612143 -0.708059 0.373424374112243 0.999957852801679 DataSet_03_285
CAV1 ZNF750 siRNA Skin Primary neonatal keratinocytes 1.66287 0.733672 0.00301013273947804 0.0459368741884404 DataSet_03_294
CAV1 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 1.82955 0.871485 0.00181176626280117 0.297985037448865 DataSet_04_001
CAV1 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 2.08929 1.06301 0.13612355691864 0.249575770766924 DataSet_04_002
CAV1 CHCHD3 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.24107 1.16419 0.0905099165968056 0.915844825866729 DataSet_04_003
CAV1 DDX59 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.640244 -0.643306 0.00377377247154372 0.518744806039141 DataSet_04_006
CAV1 EIF2AK2 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.96471 0.974313 0.0880060619865866 0.493847232938386 DataSet_04_008
CAV1 FUBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 3.63636 1.8625 0.148839904950131 0.261016729865202 DataSet_04_010
CAV1 FUBP3 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.457317 -1.12873 0.00188772550347982 0.47285050092628 DataSet_04_011
CAV1 MARK2 shRNA Haematopoietic_and_lymphoid_tissue K562 1.7963 0.845025 0.13102336738685 0.192388279586544 DataSet_04_012
CAV1 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 131.111 7.03465 0.000580907710117958 0.00902209289640242 DataSet_04_014
CAV1 NUP35 shRNA Haematopoietic_and_lymphoid_tissue K562 1.61111 0.688056 0.20679114039859 0.286562611816768 DataSet_04_015
CAV1 PAN2 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.340909 -1.55254 0.686090174379596 0.951903199101707 DataSet_04_016
CAV1 E4F1 CRISPR Liver HepG2 0.265306 -1.91427 0.0312623424696377 0.280261049717748 DataSet_04_028
CAV1 PAN2 CRISPR Liver HepG2 0.529412 -0.917538 0.0950964302105072 0.248442977967702 DataSet_04_033
CAV1 SMAD4 CRISPR Liver HepG2 0.508197 -0.976541 0.0610165760805894 0.181851281401586 DataSet_04_035
CAV1 ZNF574 CRISPR Liver HepG2 0.588235 -0.765535 0.252387334494889 0.394861746058724 DataSet_04_041
CAV1 CNOT7 CRISPR Liver HepG2 0.375 -1.41504 0.0844220509664578 0.190167329308394 DataSet_04_045
CAV1 DNMT3B CRISPR Liver HepG2 0.346939 -1.52725 0.113541392207008 0.33917646546782 DataSet_04_044
CAV1 PAN2 CRISPR Liver HepG2 0.508197 -0.976541 0.0471635924642957 0.141089248556385 DataSet_04_066
CAV1 RIOK2 CRISPR Liver HepG2 0.512195 -0.965235 0.333066135287593 1 DataSet_04_070
CAV1 SEPT11 CRISPR Liver HepG2 0.130435 -2.9386 0.0115178371743961 0.109117726181933 DataSet_04_068
CAV1 CALR shRNA Liver HepG2 0.62069 -0.688056 0.427960491955788 0.571431019614124 DataSet_04_053
CAV1 PRPF6 shRNA Liver HepG2 2.15385 1.10692 0.441635164144229 0.656856796463907 DataSet_04_056
CAV1 UBE2L3 shRNA Liver HepG2 0.478261 -1.06413 0.404853012338552 0.561296164144944 DataSet_04_055
CAV1 YBX3 shRNA Liver HepG2 0.461538 -1.11548 0.131440627721429 0.292392899147864 DataSet_02_98
CAV1 RIOK2 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.5 1.32193 0.0696524279406534 0.582132661549598 DataSet_04_076
CAV1 SEPT11 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.6281 0.703189 0.0651293264268127 1 DataSet_04_077
CAV1 SMG7 CRISPR Haematopoietic_and_lymphoid_tissue K562 2 1 0.0183512747381516 0.36988468995597 DataSet_04_075
CAV1 CITED2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.42222 1.27633 0.399606417983711 0.648110909455471 DataSet_02_38
CAV1 DPF2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.24444 1.16636 0.133209702794615 0.251154293701415 DataSet_02_14
CAV1 ERF CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.555556 -0.847997 0.292310805350693 0.469009432893042 DataSet_02_34
CAV1 HMGN3 CRISPRi Haematopoietic_and_lymphoid_tissue K562 3.24444 1.69797 0.0297653031742382 0.480607566711255 DataSet_02_45
CAV1 NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 3 1.58496 0.0834662643859663 0.40642623682262 DataSet_02_32
CAV1 SNW1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.477612 -1.06609 0.185626259793917 0.602581095176111 DataSet_02_49
CAV1 TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.53333 1.34104 0.371989238553387 0.530115178091575 DataSet_02_33
CAV1 TLE2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.71111 0.774933 0.0917880311503995 0.209068516316494 DataSet_02_53
CAV1 ABT1 shRNA Haematopoietic_and_lymphoid_tissue K562 5.93182 2.56847 0.00334560103819679 0.0321981772439248 DataSet_04_060
CAV1 CCAR1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.91765 0.939337 0.0806459010406026 0.2082850743678 DataSet_04_064
CAV1 CNOT7 shRNA Haematopoietic_and_lymphoid_tissue K562 3.21277 1.68382 0.00358309222963445 0.0584097635500595 DataSet_04_061
CAV1 HDGF shRNA Haematopoietic_and_lymphoid_tissue K562 1.80556 0.852443 0.157836489946134 0.256709871841624 DataSet_04_059
CAV1 UBE2L3 shRNA Haematopoietic_and_lymphoid_tissue K562 4.2069 2.07276 0.00313551878460645 0.0832486226804717 DataSet_04_062
CAV1 KDM5A shRNA Brain NCH644 1.6172 0.6935 4.538077e-02 0.491245153 DataSet_03_316
CAV1 EZH2 shRNA Colon SW480 1.72417 0.785902 - - DataSet_03_298
CAV1 TET1 siRNA Lung H1299 0.497892 -1.0061 - - DataSet_03_319
CAV1 TET1 siRNA Lung H1299 0.497892 -1.0061 - - DataSet_03_321
CAV1 ZNF598 knockout Cervix HeLa 0.604916 -0.725192 1.825926e-02 1.0000000 DataSet_03_299
CAV1 EZH2 knockdown Uterus Ishikawa (ISK) cell 18.2101 4.18667 - - DataSet_03_324
CAV1 SNAI2 shRNA Pancreas pancreatic cancer stem cells 0.56874 -0.814158 1.146551e-02 0.5617739 DataSet_03_306
CAV1 BRCA1 siRNA Mammary_gland MCF7 0.324658 -1.62301 9.620504e-05 0.2603910 DataSet_03_308
CAV1 EZH2 shRNA Mammary_gland MCF7 2.91475 1.54337 1.235657e-05 1.102798e-03 DataSet_03_331
CAV1 TET1 CRISPR Mammary_gland MDA-MB-231 0.523211 -0.934534 4.633905e-04 7.722079e-03 DataSet_03_347
CAV1 ETV5 knockdown Colon HT29 2.66281 1.41295 1.614550e-01 0.437528915 DataSet_03_353
CAV1 CREBBP CRISPR Brain U5-NPC 2.20884 1.14329 0.2734548308 0.7490853 DataSet_03_356
CAV1 PTPN14 CRISPR Brain U5-NPC 1.67605 0.745063 1.321205e-01 0.35823981 DataSet_03_357
CAV1 TP53 CRISPR Brain U5-NPC 1.8749 0.906817 8.321472e-02 2.201021e-01 DataSet_03_358
CAV1 RUNX1 shRNA Haematopoietic_and_lymphoid_tissue OCI-AML5 2.06025 1.04282 7.208786e-02 2.758113e-01 DataSet_03_359
CAV1 TP53 knockout Stomach SNU1 21.8306 4.44828 0.0139515006 0.9301241 DataSet_03_365
CAV1 USP22 shRNA Liver PLC_PRF_5 cells 0.147448 -2.76172 2.643846e-03 0.07721955 DataSet_03_368
CAV1 ZFP36L1 siRNA Urinary_bladder J82 2.60453 1.38102 - - DataSet_03_371
CAV1 HNRNPU siRNA Colon RKO 0.300294 -1.73555 - - DataSet_03_374
CAV1 GLI1 siRNA Skeletal_muscle RMS13 1.90569 0.930314 1.812689e-03 0.028749609 DataSet_03_375
CAV1 SMARCA2 shRNA Lung NCI-H1944 1.65827 0.72968 2.436932e-02 3.032963e-01 DataSet_03_377
CAV1 DDX5 shRNA Stomach HGC-27 0.0740741 -3.75489 - - DataSet_03_379
CAV1 NFKB2 siRNA Bone_marrow U2OS 0.408177 -1.29273 7.568883e-03 0.12204505 DataSet_03_381
CAV1 TCF19 CRISPR Oral_squamous CAL27 0.603803 -0.727849 4.360964e-05 0.0043642029 DataSet_03_383
CAV1 YY1 shRNA Brain GSC1517 1.60976 0.686842 - - DataSet_03_384
CAV1 NFKBIA shRNA Bone_marrow U2OS 0.649974 -0.621545 2.157569e-04 0.15074477 DataSet_03_389
CAV1 KDM5A CRISPR Lung GLC16 1.98486 0.98904 1.831312e-02 0.062013176 DataSet_03_392
CAV1 ILF2 siRNA Stomach SGC-7901 4.60061 2.20183 0.0117382125 0.05155068 DataSet_03_393
CAV1 ASXL1 CRISPR Embryo iPSC 2.42901 1.28037 0.2764936179 0.8207323 DataSet_03_394
CAV1 IKZF2 CRISPR Lymph CAR T Cell 7.51348 2.90948 1.016609e-01 0.540092595 DataSet_03_397
CAV1 RELA CRISPR Brain T30 2.09269 1.06536 0.3133206353 0.8400824 DataSet_03_399
CAV1 SUMO1 CRISPR Bone_marrow U2OS 0.472539 -1.08149 3.236440e-04 7.023359e-03 DataSet_03_401
CAV1 EHF shRNA Stomach MKN7 2.07761 1.05493 - - DataSet_03_402
CAV1 TFAP2A knockout Embryo H9 0.131579 -2.926 4.366198e-04 0.02122994 DataSet_03_405
CAV1 MAP3K7 shRNA Prostate LNCaP 0.344444 -1.53766 1.462418e-02 1.013494e-01 DataSet_03_408
CAV1 STRAP knockout Nerve SK-N-AS 0.362783 -1.46282 - - DataSet_03_409
CAV1 USP22 shRNA Liver HuH7 2.3103 1.20808 - - DataSet_03_411
CAV1 E2F1 siRNA Prostate LNCaP 0.5 -1 7.448402e-01 0.9327351904 DataSet_03_413
CAV1 FOXK2 shRNA Ovary OVCAR-5 3.69342 1.88496 4.191015e-02 0.16473302 DataSet_03_419
CAV1 FOXQ1 CRISPR Lymph Primary CD4+ T cells 0.482759 -1.05063 - - DataSet_03_422
CAV1 MAEL CRISPR Liver Alexander cells 0.428571 -1.22239 - - DataSet_03_423
CAV1 FOXP3 CRISPR Peripheral_blood Naive Treg 0.423963 -1.23799 5.231648e-01 0.790177835 DataSet_03_427
CAV1 LHX2 shRNA Bone_marrow ES-derived RPE cells 1.94766 0.961741 1.651205e-01 1.000000e+00 DataSet_03_428
CAV1 STAT3 siRNA Peripheral_blood Monocyte-derived M-CSF macrophages 4.2 2.07039 0.1760652009 1 DataSet_03_430
CAV1 USP7 shRNA Skin xenograft cells 0.490467 -1.02777 0.27177550 0.4348960 DataSet_03_431
CAV1 PLAG1 shRNA Cord_blood Lin-CD34+ HSPCs 0.571429 -0.807355 - - DataSet_03_432
CAV1 POU2AF1 CRISPR Haematopoietic_and_lymphoid_tissue OCI-Ly7 3.5 1.80736 3.338574e-01 0.574894029 DataSet_03_434
CAV1 EP300 knockout Pancreas HPAF-II orthotopic cells 0.351032 -1.51033 5.852441e-06 2.757570e-04 DataSet_03_436
CAV1 FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 1.92031 0.941339 4.173178e-01 0.90558273 DataSet_03_439
CAV1 SETDB1 shRNA Colon HCT116 0.623826 -0.680783 - - DataSet_03_440
CAV1 HMG20A siRNA Mammary_gland MDA-MB-231 1.59073 0.669689 0.0132613993 0.1744886 DataSet_03_442
CAV1 PURA siRNA Cervix HeLa 1.74971 0.807119 2.450367e-03 0.057094083 DataSet_03_444
CAV1 FOSL1 siRNA Prostate MSKPCa3 0.481488 -1.05443 0.0040906612 0.2142419 DataSet_03_445
CAV1 CAMTA1 knockout Embryo_kidney HEK293T 1.51969 0.603772 1.146741e-01 0.28103475 DataSet_03_448
CAV1 CBX2 siRNA Mammary_gland MCF7 3.92289 1.97192 1.220683e-01 0.2226973450 DataSet_03_451
CAV1 ZFP36L1 CRISPR Lung NCI-H1876 0.436976 -1.19437 6.739463e-01 0.992381486 DataSet_03_454
CAV1 SMARCA2 shRNA Lung HCC2302 0.427914 -1.22461 2.280883e-10 1.675326e-09 DataSet_03_455
CAV1 IRF2 shRNA Cord_Blood CD34+ cells 0.433962 -1.20436 - - DataSet_03_460
CAV1 TXNIP shRNA Cord_blood ST3 14.4 3.848 2.568582e-05 0.0090004114 DataSet_03_462
CAV1 SOX9 knockout Liver HuH7 0.552589 -0.855722 4.452073e-03 2.434080e-02 DataSet_03_463
CAV1 SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 2.02193 1.01573 - - DataSet_03_467
CAV1 SMARCA1 shRNA Embryo_kidney HEK293T 1.88158 0.911944 - - DataSet_03_468
CAV1 EZH2 siRNA Prostate LNCaP 0.225968 -2.14581 - - DataSet_03_472
CAV1 CHCHD3 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.24107 1.16419 0.03092455 0.8431706 DataSet_04_071
CAV1 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 1.82955 0.871485 0.005415483 0.3569644 DataSet_04_072
CAV1 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 2.08929 1.06301 0.07190166 0.162306252 DataSet_04_074
Regulation Region
 
T(co)Fs that significantly regulate SPDEF by the evidences of both expression and ChIP-seq/motif
Expression Atlas of CAV1
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines