Gene Overview
Target Gene: OAS1
NCBI Official Symbol: OAS1
Entrez ID: 4938
Ensembl ID: ENSG00000089127
Gene Full Name: 2'-5'-oligoadenylate synthetase 1
Strand: +
Gene Locus: 12q24.13
External Links:

OAS1 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate OAS1   
T(co)Fs that Repress OAS1
The Intensity of the Gene Regulated by T(co)Fs:
OAS1-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
OAS1 HNF1B shRNA Ovary RMG2 3.93414 1.97605 0.00029 0.00152 DataSet_01_103
OAS1 ARID1A shRNA Ovary OSE4 0.41449 -1.27058 - - DataSet_01_108
OAS1 GABPA siRNA Lung A549 2.38552 1.25431 1.42746e-10 2.05988e-08 DataSet_01_113
OAS1 ID1 siRNA Lung A549 3.2868 1.71668 0.0118 0.14819 DataSet_01_117
OAS1 ID1 siRNA Lung H1650 0.40206 -1.31453 0.10817 0.45394 DataSet_01_118
OAS1 GATA3 siRNA Mammary_gland MCF7 0.43736 -1.1931 3.39234e-06 0.00031 DataSet_01_120
OAS1 FOXM1 siRNA Central_nervous_system U87 6.52021 2.70492 - - DataSet_01_122
OAS1 ZNF85 siRNA Gastrointestinal_tissue GIST-T1 1.98186 0.98686 0.00121 0.01131 DataSet_01_126
OAS1 ZNF254 siRNA Gastrointestinal_tissue GIST-T1 0.64823 -0.62543 0.01689 0.07801 DataSet_01_127
OAS1 ID1 shRNA Neuroepithelium GSC8 0.64108 -0.64141 1.48185e-08 4.10015e-08 DataSet_01_134
OAS1 SPDEF shRNA Mammary_gland MCF7 7.10819 2.82948 2.67936e-07 0.00222 DataSet_01_135
OAS1 IKZF1 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 2.12844 1.0898 0.0537 0.99993 DataSet_01_138
OAS1 POLR3A siRNA Mammary_gland MCF7 0.59192 -0.75653 - - DataSet_01_139
OAS1 ZFX shRNA Haematopoietic_and_lymphoid_tissue NOMO-1 2.73619 1.45217 0.00971 0.99999 DataSet_01_144
OAS1 TAL1 shRNA Umbilical_cord_blood ECFCs 2.34581 1.23009 0.19685 0.7485 DataSet_01_152
OAS1 MYCN siRNA Autonomic_ganglia SKNBE2 0.4401 -1.18409 0.00014 0.05014 DataSet_01_160
OAS1 ELK1 siRNA Peripheral_blood CD4+ T cells 44.3215 5.46994 2.45747e-09 2.82219e-06 DataSet_01_162
OAS1 JUN siRNA Peripheral_blood CD4+ T cells 46.2729 5.5321 1.99811e-09 2.78636e-06 DataSet_01_164
OAS1 MAF siRNA Peripheral_blood CD4+ T cells 12723.5 13.6352 0.00028 0.01099 DataSet_01_165
OAS1 NFATC3 siRNA Peripheral_blood CD4+ T cells 12888.8 13.6538 0.00118 0.02576 DataSet_01_166
OAS1 FOSL1 siRNA Mammary_gland BT549 1.70587 0.77051 5.08199e-05 0.00469 DataSet_01_171
OAS1 JUN siRNA Mammary_gland BT549 1.91592 0.93804 6.71022e-05 0.00951 DataSet_01_172
OAS1 STAT3 siRNA Oesophagus OE21 1.63814 0.71206 0.02511 0.44272 DataSet_01_180
OAS1 TP63 shRNA Bladder UC14 1.80247 0.84998 2.05595e-06 0.00011 DataSet_01_183
OAS1 STAT3 siRNA Urothelial Scaber 1.62934 0.70429 4.41518e-07 5.07137e-05 DataSet_01_184
OAS1 TCF4 siRNA Autonomic_ganglia SH-SY5Y 2.1728 1.11955 0.02367 0.12513 DataSet_01_185
OAS1 GABPA shRNA Prostate C4-2B 1420.66 10.4724 0.23808 0.43934 DataSet_01_190
OAS1 GABPA shRNA Prostate LNCaP 921.906 9.84848 0.46495 0.7048 DataSet_01_191
OAS1 TP63 siRNA Head_and_neck SCC-6 2.66177 1.41239 - - DataSet_01_202
OAS1 XBP1 shRNA Mammary_gland T47D 2.00623 1.00449 0.00026 0.00235 DataSet_01_203
OAS1 XBP1 shRNA Mammary_gland MDA-MB-231 1.88031 0.91097 5.28219e-05 0.004 DataSet_01_204
OAS1 MITF shRNA Skin COLO829 3.92745 1.97359 1.27814e-05 0.00169 DataSet_01_207
OAS1 REST siRNA Prostate LNCaP 1.87555 0.90731 0.04834 0.26397 DataSet_01_211
OAS1 EGR3 shRNA Prostate M12 0.16363 -2.61149 2.60878e-06 0.00208 DataSet_01_212
OAS1 SOX11 shRNA Lymph MCL 1.6542 0.72614 0.00126 0.19405 DataSet_01_213
OAS1 BCLAF1 shRNA Colon RKO 0.63315 -0.65939 - - DataSet_01_214
OAS1 FOXM1 siRNA Mammary_gland MCF7 88.9463 6.47486 4.05297e-05 0.02633 DataSet_01_223
OAS1 HIF1A shRNA Liver HuH7 0.4965 -1.01012 - - DataSet_01_224
OAS1 SNAI2 shRNA Skin Primary human keratinocytes 0.53237 -0.90949 0.00081 0.01395 DataSet_01_225
OAS1 KLF2 shRNA Bone_marrow RPMI8226 1.86959 0.90273 0.01645 0.5125 DataSet_01_226
OAS1 EGR2 siRNA Muscle A673 0.5498 -0.86301 0.02303 0.51582 DataSet_01_242
OAS1 EGR2 siRNA Neuroepithelium SK-N-MC 0.6329 -0.65995 0.01078 0.55607 DataSet_01_243
OAS1 TWIST1 shRNA Stomach CAF32 0.3986 -1.327 0.00038 0.01545 DataSet_01_253
OAS1 SOX4 shRNA Mammary_gland MDA-MB-231 1.72931 0.79019 0.00035 0.01923 DataSet_01_260
OAS1 IRF4 shRNA Lymph BL2 0.53245 -0.90927 - - DataSet_01_262
OAS1 SIX4 siRNA Ovary PEO1 2.84586 1.50886 0.00023 0.00589 DataSet_01_269
OAS1 SALL4 shRNA Lung H661 0.51897 -0.94628 0.18153 0.54982 DataSet_01_277
OAS1 POSTN shRNA Brain GSC272 0.32488 -1.62201 0.02992 0.51888 DataSet_01_293
OAS1 TFAP4 siRNA Brain BE(2)-C 0.12688 -2.97842 0.18922 0.51625 DataSet_01_295
OAS1 ARID1B shRNA Liver IRM90 1.99241 0.99451 0.00014 0.00389 DataSet_01_298
OAS1 SOX17 siRNA Umbilical_vein HUVEC 0.56627 -0.82045 0.38568 0.99998 DataSet_01_300
OAS1 PTEN shRNA Skin A431 3.62642 1.85855 0.00043 0.0655 DataSet_01_301
OAS1 ETV5 siRNA Soft_tissue hADSC 3.02116 1.5951 3.35812e-06 0.00083 DataSet_01_304
OAS1 OVOL2 siRNA Corneal_epithelial Corneal epithelial cells 0.41558 -1.26681 0.00071 0.14694 DataSet_01_313
OAS1 ERG siRNA Cervix HeLa 4.58294 2.19627 1.64509e-07 1.58255e-06 DataSet_01_316
OAS1 MYC siRNA Colon HCT116 1.55288 0.63494 0.0201 0.0374 DataSet_01_324
OAS1 TP63 shRNA Immortalized_keratinocyte HaCaT 1.51386 0.59824 4.81925e-07 1.78391e-05 DataSet_01_325
OAS1 TP63 shRNA Immortalized_keratinocyte HaCaT 1.51386 0.59824 4.81925e-07 1.78391e-05 DataSet_01_328
OAS1 REST siRNA Skin NHEK 1.70896 0.77312 0.00385 0.06199 DataSet_01_337
OAS1 GATA3 siRNA Oral_cavity OEC-M1 0.40505 -1.30383 0.10507 0.99787 DataSet_01_347
OAS1 SOX2 shRNA Neuroepithelium HF2303 0.53201 -0.91047 0.06693 1 DataSet_01_349
OAS1 ELK1 siRNA Mammary_gland MDA-MB-231 1.80327 0.85061 - - DataSet_01_354
OAS1 ETV4 shRNA Prostate PC3 1.98953 0.99243 - - DataSet_01_356
OAS1 PAX3 shRNA Soft_tissue Rh30 1.52869 0.6123 - - DataSet_01_359
OAS1 SOX17 siRNA Umbilical_vein HUVEC 1.61423 0.69085 - - DataSet_01_360
OAS1 SSB shRNA Liver HepG2 0.14318 -2.80407 0.01494 0.03525 DataSet_02_107
OAS1 ZNF622 shRNA Liver HepG2 1.91097 0.9343 0.00455 0.01742 DataSet_02_108
OAS1 HNRNPUL1 shRNA Liver HepG2 1.51854 0.60269 0.03752 0.08749 DataSet_02_109
OAS1 GTF2F1 shRNA Liver HepG2 1.92916 0.94797 0.0156 0.23265 DataSet_02_110
OAS1 U2AF2 shRNA Liver HepG2 2.07085 1.05022 0.01372 0.07685 DataSet_02_113
OAS1 XRCC5 shRNA Liver HepG2 0.62412 -0.6801 0.01011 0.14276 DataSet_02_114
OAS1 PTBP1 shRNA Liver HepG2 2.35904 1.2382 0.00216 0.00933 DataSet_02_120
OAS1 EWSR1 shRNA Liver HepG2 2.47067 1.3049 0.00184 0.04273 DataSet_02_122
OAS1 FUS shRNA Liver HepG2 1.62061 0.69654 0.0035 0.0629 DataSet_02_124
OAS1 HNRNPLL shRNA Liver HepG2 0.53339 -0.90673 0.00405 0.02103 DataSet_02_125
OAS1 SNRNP70 shRNA Liver HepG2 1.92004 0.94113 0.0113 0.05483 DataSet_02_126
OAS1 SRSF3 shRNA Liver HepG2 2.76274 1.4661 0.00095 0.0662 DataSet_02_127
OAS1 CCAR2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.16667 -2.58496 0.02715 0.47274 DataSet_02_146
OAS1 HNRNPL shRNA Haematopoietic_and_lymphoid_tissue K562 2.5 1.32193 0.05694 0.20101 DataSet_02_160
OAS1 AGO1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.31818 -1.65208 0.04773 0.54825 DataSet_02_162
OAS1 ZFX siRNA Prostate C4-2B 3.89535 1.96175 0.0149 0.04195 DataSet_02_172
OAS1 MXI1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.42857 -1.22239 0.63044 1 DataSet_02_173
OAS1 CEBPZ siRNA Haematopoietic_and_lymphoid_tissue K562 2 1 0.20805 1 DataSet_02_176
OAS1 MAFK siRNA Haematopoietic_and_lymphoid_tissue K562 1.66667 0.73697 0.27163 1 DataSet_02_183
OAS1 CTCF siRNA Haematopoietic_and_lymphoid_tissue K562 4 2 0.11123 1 DataSet_02_185
OAS1 CDAN1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.66667 0.73697 0.28876 1 DataSet_02_197
OAS1 BRCA1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.42857 -1.22239 0.62185 1 DataSet_02_202
OAS1 RCOR1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.66667 0.73697 0.26728 1 DataSet_02_204
OAS1 AR siRNA Prostate LNCaP 1.72419 0.785919 0.272995208135166 1 DataSet_03_005
OAS1 BCL6 siRNA Mammary_gland MCF7 2.51803 1.3323 0.0434243942544101 0.989541443114508 DataSet_03_024
OAS1 BCL6 siRNA Lymph Pfeiffer DLBCL 0.554877 -0.849761 0.000443844359486454 0.118314833051446 DataSet_03_026
OAS1 BRCA1 siRNA Mammary_gland MCF7 0.519798 -0.943978 0.122833152602379 0.999850583334387 DataSet_03_028
OAS1 CENPF siRNA Mammary_gland MCF7 2.07296 1.05169 0.0920014334662978 0.999662524742916 DataSet_03_052
OAS1 CTNNB1 siRNA Mammary_gland MCF7 2.40427 1.2656 0.0518409825183095 0.999436862066063 DataSet_03_058
OAS1 E2F1 siRNA Mammary_gland MCF7 2.34001 1.22651 0.0575414068040898 0.999927373439084 DataSet_03_061
OAS1 E2F5 siRNA Mammary_gland MCF7 2.08549 1.06038 0.0898759057007154 0.999540347732068 DataSet_03_062
OAS1 E2F7 siRNA Upper_aerodigestive_tract SCC25 2.39078 1.25748 4.80487681659115e-09 1.86796334667476e-06 DataSet_03_063
OAS1 ESR1 siRNA Mammary_gland MCF7 0.478274 -1.06409 1.48625653082271e-05 0.00254263737899141 DataSet_03_071
OAS1 ESRRA siRNA Mammary_gland MCF7 0.555238 -0.848821 0.158224226661659 0.999964003642835 DataSet_03_072
OAS1 FOXA1 siRNA Mammary_gland MCF7 0.615527 -0.700107 0.000121453928099051 0.0013530421185072 DataSet_03_081
OAS1 FOXA1 siRNA Mammary_gland MCF7 0.615527 -0.700107 0.000121453928099051 0.0013530421185072 DataSet_03_082
OAS1 FOXO1 shRNA Haematopoietic_and_lymphoid_tissue Namalwa 1.82077 0.86455 0.00014255429090461 0.0263691496675694 DataSet_03_095
OAS1 FOXO1 siRNA Skin primary human dermal lymphatic endothelial cells 2.17701 1.12234 - - DataSet_03_096
OAS1 GATA2 siRNA Uterus Decidual stromal cells 2.00548 1.00395 0.373276542255548 0.896415157927495 DataSet_03_100
OAS1 GATA3 siRNA Mammary_gland MCF7 0.559283 -0.838349 0.00343008444313587 0.0591157076928528 DataSet_03_103
OAS1 GATA6 siRNA Stomach KatoIII 0.605639 -0.723471 0.00299291903041806 0.253170553139465 DataSet_03_109
OAS1 GFP siRNA Upper_aerodigestive_tract SCC25 1.83904 0.878956 1.44697624328152e-06 0.000134584349509518 DataSet_03_112
OAS1 HDAC3 siRNA Mammary_gland MCF7 2.84671 1.5093 0.0273311302366109 0.99997791025972 DataSet_03_114
OAS1 HDAC5 siRNA Mammary_gland MCF7 2.23802 1.16223 0.0683558439448458 0.999966625300244 DataSet_03_115
OAS1 HES6 siRNA Brain A172 0.630515 -0.665397 0.0153649808358292 0.999995680871491 DataSet_03_116
OAS1 HIF1A siRNA Mammary_gland MCF7 1.97349 0.980748 0.111312676870583 0.999966843283762 DataSet_03_119
OAS1 HMGA1 siRNA Mammary_gland MDA-MB-231 1.72858 0.78959 2.99227343059837e-08 2.01235034595055e-06 DataSet_03_124
OAS1 HNF4a siRNA Liver HepG2 0.666292 -0.585774 0.174264407957826 0.785301853394449 DataSet_03_126
OAS1 HOXB7 siRNA Mammary_gland MCF7 0.648949 -0.623823 0.282507062349241 0.999977683706165 DataSet_03_127
OAS1 HSF2 siRNA Mammary_gland MCF7 1.78622 0.836912 0.163279867374595 0.990969613280381 DataSet_03_130
OAS1 IRF4 siRNA Skin Cutaneous T cell lymphoma HuT-102 cells 3.77097 1.91493 0.00961435995575364 0.59575244460433 DataSet_03_134
OAS1 JARID1A siRNA Autonomic_ganglia SKNBE2 0.413273 -1.27483 0.00640164095971371 0.23281439880233 DataSet_03_135
OAS1 JUND siRNA Mammary_gland MCF7 0.664047 -0.590643 0.794613900335505 0.999848956486105 DataSet_03_145
OAS1 Klf4 siRNA Skin Primary neonatal keratinocytes 1.65788 0.729337 0.0106691803326162 0.0465245872136133 DataSet_03_147
OAS1 MAFB siRNA Peripheral_blood Monocyte-derived M-CSF macrophages 0.552227 -0.856667 0.137054333375109 1 DataSet_03_155
OAS1 MEF2D shRNA Liver HuH7 4.49916 2.16966 - - DataSet_03_162
OAS1 MITF siRNA Skin SK-MEL-5 0.609465 -0.714384 0.00206913849448236 0.00606473824079231 DataSet_03_168
OAS1 MYB siRNA Cord_Blood CD34+ progenitor cells 2.64266 1.40199 - - DataSet_03_170
OAS1 MYC siRNA Colon HT29 3.04368 1.60582 - - DataSet_03_177
OAS1 MYC siRNA Central_nervous_system DAOY M2.1 3.28902 1.71766 1.97495278605857e-08 6.04062183362972e-07 DataSet_03_178
OAS1 MYC siRNA Haematopoietic_and_lymphoid_tissue B-cell lymphoma cell line Blue1 1.51572 0.6 0.000968689137920502 0.307484751942852 DataSet_03_180
OAS1 MYCN siRNA Autonomic_ganglia SKNBE2 0.440104 -1.18409 0.000135881223234276 0.0507261591185134 DataSet_03_185
OAS1 NFAT5 siRNA Synovial Primary fibroblast-like synoviocytes 1.77629 0.828864 0.200309097507128 0.60680282377397 DataSet_03_194
OAS1 NFAT5 siRNA Umbilical_vein HUVEC 2.4452 1.28995 9.79179603681065e-06 0.00144034652675327 DataSet_03_195
OAS1 NR4A3 siRNA Pancreas 1.1B4 1.59445 0.673062 5.77385456716836e-05 0.000536852482132585 DataSet_03_203
OAS1 PBX1 siRNA Mammary_gland MCF7 1.51252 0.596951 0.000171437692573315 0.395472469228122 DataSet_03_207
OAS1 PBX1 siRNA Mammary_gland LTED 1.91495 0.937308 0.00229834606946028 0.99990029707784 DataSet_03_208
OAS1 PCNA siRNA Mammary_gland MCF7 2.61099 1.3846 0.0378277789491753 0.999448838103647 DataSet_03_210
OAS1 RARA siRNA Mammary_gland MCF7 0.523848 -0.932779 1.24885072203696e-05 0.00178831638999565 DataSet_03_218
OAS1 RB1 siRNA Mammary_gland MCF7 1.84004 0.879734 0.145779273027479 0.999890290262508 DataSet_03_219
OAS1 RBL2 siRNA Mammary_gland MCF7 4.33566 2.11625 0.0062437888099378 0.999927471951507 DataSet_03_220
OAS1 RELB siRNA Pancreas MIA PaCa-2 3.72908 1.89882 1.12646447963575e-06 0.004467488941496 DataSet_03_225
OAS1 SOX2 siRNA Mammary_gland GSC-11 0.498285 -1.00496 0.0322913391590956 0.157793950478325 DataSet_03_245
OAS1 SP1 siRNA Cervix HeLa 2.69105 1.42817 7.8539183038929e-07 0.000125982667311704 DataSet_03_249
OAS1 SP1 siRNA Ovary OVSAYO 5.52321 2.46551 0.00358124129553423 0.0924822591015329 DataSet_03_251
OAS1 SRF siRNA Prostate LNCaP 1.62808 0.703173 0.101946114020573 0.329056953214415 DataSet_03_254
OAS1 STAT3 CRISPR Embryo hESC 0.036705 -4.76788 0.00846423577790121 0.0603510275688178 DataSet_03_258
OAS1 STAT5B siRNA Mammary_gland MCF7 2.09009 1.06356 0.0891103857082344 0.999932708473107 DataSet_03_263
OAS1 TCEA1 siRNA Mammary_gland MCF7 2.6916 1.42847 0.0337175785783881 0.999762252994287 DataSet_03_266
OAS1 TFAP2C siRNA Mammary_gland MCF7 25.5732 4.67656 0.00154928024483479 0.184703246713571 DataSet_03_274
OAS1 TP53 siRNA Mammary_gland MCF7 2.36194 1.23997 0.0555088552966926 0.999938217444253 DataSet_03_277
OAS1 TP63 siRNA Skin Primary neonatal keratinocytes 2.94596 1.55874 6.36319906258716e-05 0.0024140063205812 DataSet_03_281
OAS1 TP63 siRNA Foreskin Neonatal foreskin keratinocytes 2.4639 1.30095 0.0227333789979373 0.729684006943091 DataSet_03_282
OAS1 ZNF750 siRNA Skin Primary neonatal keratinocytes 2.13266 1.09266 0.025330484979163 0.131375721423192 DataSet_03_294
OAS1 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 231.724 7.85626 0.105587220816774 0.221762041383113 DataSet_04_014
OAS1 YBX1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.448276 -1.15754 0.170993619348184 0.577667411580903 DataSet_04_022
OAS1 ERN1 CRISPR Liver HepG2 0.630096 -0.666357 0.00366246100099806 0.0740917584049855 DataSet_04_029
OAS1 YBX1 CRISPR Liver HepG2 0.584139 -0.775618 0.575011424224659 0.972884761036538 DataSet_04_039
OAS1 ZC3H8 shRNA Liver HepG2 0.534104 -0.904807 0.00476332714538464 0.0853116958887745 DataSet_04_040
OAS1 ACTN4 CRISPR Liver HepG2 1.63562 0.709837 0.0270219757647281 0.0909230457653166 DataSet_04_042
OAS1 ABT1 shRNA Liver HepG2 4.79595 2.26182 0.000156698250801781 0.00317141520956635 DataSet_04_052
OAS1 CCAR1 shRNA Liver HepG2 3.28481 1.71581 6.94802744883266e-05 0.0077627032912778 DataSet_04_054
OAS1 DDX1 shRNA Liver HepG2 1.69007 0.757083 0.00516232260923095 0.0825370648605097 DataSet_04_057
OAS1 PRPF6 shRNA Liver HepG2 0.595032 -0.748961 0.00239233335729324 0.0445107412946865 DataSet_04_056
OAS1 UBE2L3 shRNA Liver HepG2 1.62958 0.704499 0.000594615651973881 0.00945203727906051 DataSet_04_055
OAS1 YBX3 shRNA Liver HepG2 0.471853 -1.08359 0.00216362311183992 0.0479435975796516 DataSet_02_98
OAS1 DDX20 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.66667 1.41504 0.632904735883304 0.885126809744738 DataSet_04_050
OAS1 SMG5 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.272727 -1.87447 0.488658278482822 0.811305838729753 DataSet_04_073
OAS1 SMG7 CRISPR Haematopoietic_and_lymphoid_tissue K562 3.09091 1.62803 0.406264529434601 0.728357200435775 DataSet_04_075
OAS1 SNW1 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.90909 0.932886 0.464368887398356 0.632445800522064 DataSet_04_049
OAS1 DPF2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.104478 -3.25873 0.0116338105815396 0.0417190520648494 DataSet_02_14
OAS1 ERF CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.208955 -2.25873 0.0225067060405806 0.0752204215734097 DataSet_02_34
OAS1 HMGA1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.62069 1.38995 0.108486272771681 0.496507366864173 DataSet_02_75
OAS1 NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.62687 1.39334 0.0829728338085782 0.406097081759288 DataSet_02_32
OAS1 TBL1XR1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.55224 1.35176 0.388635627519003 0.579117351013682 DataSet_02_43
OAS1 TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.50746 0.592122 0.453177425576837 0.614507174253701 DataSet_02_33
OAS1 TLE2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.71642 1.44171 0.00589216258465412 0.0428460973953585 DataSet_02_53
OAS1 UBE2L3 shRNA Haematopoietic_and_lymphoid_tissue K562 3 1.58496 0.211783083079119 0.457886115734208 DataSet_04_062
OAS1 EZH2 shRNA Colon SW480 1.9599 0.97078 - - DataSet_03_298
OAS1 DNMT1 siRNA Lung_fibroblast IMR-90 1.60416 0.681822 3.102118e-01 0.9999458 DataSet_03_317
OAS1 NFKBIZ knockout Colon Colon organoid 0.603237 -0.729204 3.125669e-01 0.727970061 DataSet_03_323
OAS1 AEBP1 siRNA Umbilical_vein HUVEC 1.78316 0.834436 1.172600e-03 0.563238092 DataSet_03_300
OAS1 SMARCA4 siRNA Colon HCT116 0.331837 -1.59145 1.276961e-03 0.1301247 DataSet_03_302
OAS1 ELF3 CRISPR Bile_duct HBDEC2 0.538126 -0.893983 3.716948e-03 1.644035e-02 DataSet_03_304
OAS1 ELF3 knockdown Bile_duct HBDEC2 0.274908 -1.86298 1.972490e-01 3.374942e-01 DataSet_03_305
OAS1 SNAI2 shRNA Pancreas pancreatic cancer stem cells 1.66775 0.737901 1.807227e-02 0.6006470 DataSet_03_306
OAS1 SNAI2 shRNA Pancreas KLM1 0.455166 -1.13554 2.621732e-02 0.23166609 DataSet_03_307
OAS1 ACTR5 siRNA Muscle RD 0.392853 -1.34794 - - DataSet_03_343
OAS1 EZH2 shRNA Mammary_gland MCF7 2.01588 1.01141 6.653096e-06 7.105531e-04 DataSet_03_331
OAS1 TET1 CRISPR Mammary_gland MDA-MB-231 22.4427 4.48817 2.671721e-02 1.155042e-01 DataSet_03_347
OAS1 ZFX siRNA Prostate C4-2B 1.80734 0.853869 1.425511e-02 2.919782e-02 DataSet_03_348
OAS1 SKI CRISPR Blood HL60 0.573018 -0.803347 3.635017e-02 0.337473069 DataSet_03_351
OAS1 ETV5 knockdown Colon HT29 0.15598 -2.68056 6.839787e-06 0.008453315 DataSet_03_353
OAS1 PARP1 siRNA Prostate LNCaP 1.81361 0.858863 2.689407e-01 0.564621925 DataSet_03_354
OAS1 TET1 CRISPR Mammary_gland Hs578T 15.5696 3.96066 4.527714e-04 7.697791e-03 DataSet_03_355
OAS1 CREBBP CRISPR Brain U5-NPC 2.125 1.08746 0.3633504222 0.7490853 DataSet_03_356
OAS1 PTPN14 CRISPR Brain U5-NPC 6.81034 2.76773 5.106667e-01 0.70680078 DataSet_03_357
OAS1 TP53 CRISPR Brain U5-NPC 12.9688 3.69697 1.559815e-03 1.623145e-01 DataSet_03_358
OAS1 RUNX1 shRNA Haematopoietic_and_lymphoid_tissue OCI-AML5 4.57959 2.19522 3.759793e-04 3.380131e-02 DataSet_03_359
OAS1 EP300 shRNA Mammary_gland MCF10AT 1.59716 0.675506 1.837370e-02 0.100405838 DataSet_03_364
OAS1 TP53 knockout Stomach SNU1 1.85116 0.888429 0.6625141265 0.9766057 DataSet_03_365
OAS1 ZNF148 shRNA Mammary_gland MDA-MB-231 2.49862 1.32113 3.027090e-03 0.043542897 DataSet_03_366
OAS1 ZFP36L1 siRNA Urinary_bladder J82 2.4878 1.31487 - - DataSet_03_371
OAS1 BHLHE40 shRNA Cervix HeLaS3 5.03639 2.33239 5.815769e-01 0.92761365 DataSet_03_372
OAS1 ZNF213 siRNA Mammary_gland MCF7 1.77752 0.829868 2.469218e-02 2.778024e-01 DataSet_03_376
OAS1 EZH2 CRISPR Ovary SKOV3 4.4375 2.14975 7.011783e-04 0.0172034059 DataSet_03_378
OAS1 DNMT1 siRNA Skin Human melanoma cells 3.22976 1.69143 1.245846e-06 3.278754e-05 DataSet_03_382
OAS1 TCF19 CRISPR Oral_squamous CAL27 1.78837 0.838646 5.852151e-04 0.0145536939 DataSet_03_383
OAS1 KAT6A CRISPR Haematopoietic_and_lymphoid_tissue MOLM-13 6.3673 2.67068 0.1559000298 0.8388073 DataSet_03_387
OAS1 TRIM8 siRNA Mammary_gland MCF7 13.9449 3.80167 1.961061e-02 0.0821162088 DataSet_03_388
OAS1 NFKBIA shRNA Bone_marrow U2OS 0.173299 -2.52866 9.747044e-01 0.98910899 DataSet_03_389
OAS1 YY1 knockdown Liver HepG2 5.53 2.46728 9.744267e-09 2.911489e-07 DataSet_03_390
OAS1 KDM5A CRISPR Lung GLC16 6.84894 2.77588 1.261822e-01 0.238792854 DataSet_03_392
OAS1 ASXL1 CRISPR Embryo iPSC 0.445735 -1.16574 0.1986440722 0.8187866 DataSet_03_394
OAS1 RELA CRISPR Brain T30 0.470675 -1.0872 0.1313070333 0.8400824 DataSet_03_399
OAS1 SUMO1 CRISPR Bone_marrow U2OS 6.6 2.72247 2.985993e-04 6.739022e-03 DataSet_03_401
OAS1 EHF shRNA Stomach MKN7 25.5461 4.67503 - - DataSet_03_402
OAS1 CHD1 shRNA Prostate LNCaP 0.260828 -1.93883 9.706671e-03 2.243500e-01 DataSet_03_407
OAS1 MAP3K7 shRNA Prostate LNCaP 0.189605 -2.39893 2.322025e-03 3.364517e-02 DataSet_03_408
OAS1 E2F1 siRNA Prostate LNCaP 3.42197 1.77482 8.895629e-07 0.0030848931 DataSet_03_413
OAS1 E2F2 siRNA Prostate LNCaP 3.84393 1.94258 3.472407e-08 7.662296e-05 DataSet_03_414
OAS1 ZKSCAN3 CRISPR Colon HCT116 0.00731707 -7.09452 8.109524e-05 0.017755522 DataSet_03_415
OAS1 RUNX2 shRNA Cord_blood Natural Killer Cell 0.601711 -0.732857 5.103758e-01 0.822418152 DataSet_03_416
OAS1 NFATC2 shRNA Haematopoietic_and_lymphoid_tissue THP-1 0.598321 -0.741008 7.153596e-02 0.207360408 DataSet_03_418
OAS1 FOXK2 shRNA Ovary OVCAR-5 0.233793 -2.0967 3.732053e-02 0.15523001 DataSet_03_419
OAS1 PRDM1 CRISPR Lymph CD8+ T cells 3.55222 1.82872 - - DataSet_03_421
OAS1 MAEL CRISPR Liver Alexander cells 0.249357 -2.00371 - - DataSet_03_423
OAS1 FOXP3 CRISPR Peripheral_blood Naive Treg 2.23563 1.16068 6.792370e-02 0.354928368 DataSet_03_427
OAS1 USP7 shRNA Skin xenograft cells 0.365069 -1.45376 0.25943988 0.4348960 DataSet_03_431
OAS1 PLAG1 shRNA Cord_blood Lin-CD34+ HSPCs 0.557692 -0.842459 - - DataSet_03_432
OAS1 NFE2L1 knockout Lung A549 1.57544 0.655759 1.165071e-01 7.634105e-01 DataSet_03_433
OAS1 POU2AF1 CRISPR Lymph SUDHL4 2.22194 1.15182 1.585462e-04 0.006317888 DataSet_03_435
OAS1 EP300 knockout Pancreas HPAF-II orthotopic cells 0.611204 -0.710273 3.652604e-04 3.898626e-03 DataSet_03_436
OAS1 SUFU shRNA Mammary_gland HCC1954 cells 0.601653 -0.732997 0.0859895831 0.6236973 DataSet_03_437
OAS1 FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 6.28571 2.65208 9.516123e-02 0.90558273 DataSet_03_439
OAS1 SETDB1 shRNA Colon HCT116 0.638402 -0.647464 - - DataSet_03_440
OAS1 DAXX shRNA Mammary_gland MDA-MB-231 0.179757 -2.47588 6.542507e-04 0.04480740 DataSet_03_441
OAS1 PHF14 siRNA Mammary_gland MDA-MB-231 0.656522 -0.607085 0.0231243479 0.3557304 DataSet_03_443
OAS1 FOSL1 siRNA Prostate MSKPCa3 1.7201 0.782496 0.1201028486 0.5082498 DataSet_03_445
OAS1 RELB CRISPR Colon SW480 1.67895 0.747557 8.108518e-03 6.974224e-02 DataSet_03_449
OAS1 CBX2 siRNA Mammary_gland MCF7 2.59636 1.37649 5.355742e-01 0.6973956985 DataSet_03_451
OAS1 OGT siRNA Embryo BeWo cells 2.2 1.1375 2.721115e-03 0.24417287 DataSet_03_453
OAS1 SMARCA2 shRNA Lung HCC2302 8.28421 3.05036 5.379947e-07 1.518153e-06 DataSet_03_455
OAS1 SREBF2 siRNA Umbilical_vein HUVEC 3.3382 1.73907 2.262715e-01 6.734409e-01 DataSet_03_457
OAS1 HAND1 siRNA Placenta HPMVEC 1.65 0.722466 4.728598e-01 0.9463341 DataSet_03_459
OAS1 TXNIP shRNA Cord_blood ST3 1.77193 0.825321 9.523760e-01 0.9816293280 DataSet_03_462
OAS1 SOX9 knockout Liver HuH7 0.635514 -0.654004 6.172333e-02 1.644533e-01 DataSet_03_463
OAS1 PARP1 knockout Embryo_kidney HEK293a 0.436214 -1.19689 2.247092e-03 9.159623e-03 DataSet_03_464
OAS1 LIN28A siRNA Mammary_gland MCF7M 2.43845 1.28596 5.220176e-03 0.1821968 DataSet_03_469
OAS1 LIN28A siRNA Mammary_gland MCF7M 2.43845 1.28596 5.220176e-03 0.1821968 DataSet_03_470
OAS1 WHSC1 siRNA Prostate PC3 0.523636 -0.933363 1.266553e-02 0.11715776 DataSet_03_471
OAS1 HMGB2 knockdown Umbilical_vein HUVEC 0.592593 -0.754888 3.915053e-02 0.14091062 DataSet_03_476
OAS1 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.7693132 0.9610517 DataSet_04_072
Regulation Region
 
T(co)Fs that significantly regulate NFATC3 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of OAS1
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines