Gene Overview
Target Gene: GBP3
NCBI Official Symbol: GBP3
Entrez ID: 2635
Ensembl ID: ENSG00000117226
Gene Full Name: guanylate binding protein 3
Strand: -
Gene Locus: 1p22.2
External Links:

GBP3 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate GBP3   
T(co)Fs that Repress GBP3
The Intensity of the Gene Regulated by T(co)Fs:
GBP3-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
GBP3 IRF6 shRNA Fetal_liver Primary CD34+ hematopoietic stem/progenitor cells (HSPCs) 2.03617 1.02586 6.8353e-05 0.00455 DataSet_01_101
GBP3 MYB shRNA Fetal_liver Primary CD34+ hematopoietic stem/progenitor cells (HSPCs) 2.50454 1.32454 1.43477e-06 1.73351e-05 DataSet_01_102
GBP3 HNF1B shRNA Ovary RMG2 7.31343 2.87055 0.00044 0.00215 DataSet_01_103
GBP3 ARID1A shRNA Ovary OSE4 0.51061 -0.9697 - - DataSet_01_108
GBP3 GABPA siRNA Lung A549 4.74023 2.24496 1.04468e-09 7.55485e-08 DataSet_01_113
GBP3 ID1 siRNA Lung A549 8.96225 3.16386 0.00011 0.08908 DataSet_01_117
GBP3 ZIC2 siRNA Pancreas PANC1 3.2093 1.68226 - - DataSet_01_121
GBP3 FOXM1 siRNA Central_nervous_system U87 3.5938 1.84551 - - DataSet_01_122
GBP3 ZNF43 siRNA Gastrointestinal_tissue GIST-T1 0.50329 -0.99053 4.04118e-05 0.00422 DataSet_01_125
GBP3 ZNF254 siRNA Gastrointestinal_tissue GIST-T1 0.47071 -1.08709 1.89636e-05 0.00124 DataSet_01_127
GBP3 ZNF431 siRNA Gastrointestinal_tissue GIST-T1 0.42753 -1.2259 6.96505e-06 0.00045 DataSet_01_128
GBP3 ZNF708 siRNA Gastrointestinal_tissue GIST-T1 0.64156 -0.64035 0.00105 0.01884 DataSet_01_130
GBP3 SPDEF shRNA Mammary_gland MCF7 2.03629 1.02595 1e-04 0.01414 DataSet_01_135
GBP3 IKZF2 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 1.52811 0.61174 0.1998 0.99993 DataSet_01_137
GBP3 IKZF1 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 1.552 0.63413 0.30326 0.99993 DataSet_01_138
GBP3 HSF1 shRNA Skin A375 0.41924 -1.25417 0.00899 0.06057 DataSet_01_155
GBP3 JUN siRNA Peripheral_blood CD4+ T cells 764.229 9.57786 0.01236 0.07801 DataSet_01_164
GBP3 MAF siRNA Peripheral_blood CD4+ T cells 444.432 8.79582 0.07485 0.33906 DataSet_01_165
GBP3 JUN siRNA Mammary_gland BT549 1.52991 0.61345 0.0046 0.14845 DataSet_01_172
GBP3 TCF4 siRNA Autonomic_ganglia SH-SY5Y 6.46003 2.69154 0.00023 0.01669 DataSet_01_185
GBP3 CREB1 shRNA Parotid_gland HSY 1.70336 0.76838 0.00815 0.36005 DataSet_01_195
GBP3 TP63 siRNA Head_and_neck SCC-1 1.84434 0.8831 - - DataSet_01_199
GBP3 XBP1 shRNA Mammary_gland MDA-MB-231 8.26214 3.04652 2.06631e-07 0.00062 DataSet_01_204
GBP3 MITF shRNA Skin COLO829 1.71933 0.78185 0.00047 0.01389 DataSet_01_207
GBP3 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 3.35159 1.74485 - - DataSet_01_209
GBP3 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 1.68117 0.74947 - - DataSet_01_210
GBP3 REST siRNA Prostate LNCaP 0.53675 -0.89768 0.14849 0.42806 DataSet_01_211
GBP3 EGR3 shRNA Prostate M12 0.61667 -0.69744 0.06475 0.25836 DataSet_01_212
GBP3 LIN28A siRNA Embryo H9 4.29254 2.10183 9.59303e-05 0.00294 DataSet_01_215
GBP3 TAL1 shRNA Haematopoietic_and_lymphoid_tissue HEL 0.66328 -0.59232 0.00106 0.01486 DataSet_01_217
GBP3 SNAI2 shRNA Skin Primary human keratinocytes 0.54594 -0.87318 0.00066 0.013 DataSet_01_225
GBP3 MYC siRNA White_adipose_tissue Adipose stem cells 1.59862 0.67682 3.31469e-07 1e-04 DataSet_01_231
GBP3 ZEB1 siRNA Cervix HeLa229 1.50707 0.59175 - - DataSet_01_232
GBP3 FOXA1 siRNA Prostate LNCaP 2.60626 1.38198 0.00316 0.10368 DataSet_01_233
GBP3 FOXP1 siRNA Prostate LNCaP 1.57291 0.65344 0.08147 0.47513 DataSet_01_234
GBP3 MYC shRNA Soft_tissue HT1080 3.86776 1.9515 - - DataSet_01_237
GBP3 TWIST1 shRNA Stomach CAF32 0.63732 -0.6499 0.02152 0.08123 DataSet_01_253
GBP3 SIX4 siRNA Ovary PEO1 0.60983 -0.71352 0.01231 0.07844 DataSet_01_269
GBP3 AR shRNA Prostate CWR22Pc 1.55673 0.63852 0.16696 0.36897 DataSet_01_278
GBP3 STAT5 shRNA Prostate CWR22Pc 1.56958 0.65038 0.15007 0.31065 DataSet_01_279
GBP3 ZIC5 siRNA Skin A375 1.89729 0.92394 - - DataSet_01_284
GBP3 ZIC5 siRNA Skin SK-MEL-28 0.62576 -0.67632 - - DataSet_01_285
GBP3 NFYA shRNA Lung H322 2.01964 1.0141 2.74851e-06 0.00027 DataSet_01_288
GBP3 SNAI2 siRNA Mammary_gland MCFDCIS 1.62744 0.70261 0.26607 0.76991 DataSet_01_292
GBP3 POSTN shRNA Brain GSC272 0.43046 -1.21607 0.07347 0.54319 DataSet_01_293
GBP3 TFAP4 siRNA Brain BE(2)-C 0.29227 -1.77462 0.45731 0.51665 DataSet_01_295
GBP3 PTEN shRNA Skin A431 3.93627 1.97683 0.00078 0.0655 DataSet_01_301
GBP3 PTEN shRNA Mammary_gland SKBR3 0.5914 -0.75779 0.00446 0.425 DataSet_01_303
GBP3 NR2E1 shRNA Neuroepithelium PBT003 0.56383 -0.82666 0.34566 0.73158 DataSet_01_306
GBP3 BRD4 siRNA Ovary Ovcar8 0.23554 -2.08594 1.57215e-06 3e-04 DataSet_01_311
GBP3 ARNT siRNA Upper_aerodigestive_tract HSC3 0.24856 -2.00831 - - DataSet_01_315
GBP3 ELK3 shRNA Mammary_gland MDA-MB-231 0.04726 -4.40338 2.31731e-08 6.69044e-06 DataSet_01_318
GBP3 MYC siRNA Colon HCT116 8.85455 3.14642 4.93784e-11 4.46333e-09 DataSet_01_324
GBP3 HIF1A siRNA Oral_cavity OEC-M1 0.66363 -0.59155 0.23395 0.85151 DataSet_01_348
GBP3 SMAD3 siRNA Pancreas BxPC-3 0.55993 -0.83667 - - DataSet_01_352
GBP3 ZNF24 siRNA Embryo_kidney HEK293 0.5924 -0.75535 - - DataSet_01_353
GBP3 PAX3 shRNA Soft_tissue Rh30 1.73645 0.79614 - - DataSet_01_359
GBP3 SOX17 siRNA Umbilical_vein HUVEC 1.72187 0.78398 - - DataSet_01_360
GBP3 GTF2B siRNA Cervix HeLa 1.72783 0.78896 - - DataSet_01_362
GBP3 SAFB2 shRNA Liver HepG2 1.89103 0.91917 0.1021 0.1754 DataSet_02_102
GBP3 FIP1L1 shRNA Liver HepG2 5.68831 2.508 0.01459 0.05113 DataSet_02_103
GBP3 TAF15 shRNA Liver HepG2 2.475 1.30743 0.07442 0.12114 DataSet_02_106
GBP3 SSB shRNA Liver HepG2 2.2037 1.13993 0.17809 0.24078 DataSet_02_107
GBP3 ZNF622 shRNA Liver HepG2 4.05128 2.01838 0.06109 0.10448 DataSet_02_108
GBP3 GTF2F1 shRNA Liver HepG2 2.49074 1.31657 0.17636 0.50267 DataSet_02_110
GBP3 RBM39 shRNA Liver HepG2 2.92537 1.54862 0.04336 0.24601 DataSet_02_111
GBP3 BCLAF1 shRNA Liver HepG2 2.55556 1.35364 0.01202 0.05355 DataSet_02_112
GBP3 U2AF2 shRNA Liver HepG2 2.72388 1.44566 0.86229 0.91494 DataSet_02_113
GBP3 XRCC5 shRNA Liver HepG2 0.62037 -0.6888 0.54578 0.70631 DataSet_02_114
GBP3 PCBP1 shRNA Liver HepG2 3.75 1.90689 0.02646 0.06033 DataSet_02_115
GBP3 TARDBP shRNA Liver HepG2 0.16549 -2.59516 0.01769 0.05223 DataSet_02_116
GBP3 SUB1 shRNA Liver HepG2 1.86111 0.89616 0.28546 0.47622 DataSet_02_117
GBP3 CEBPZ shRNA Liver HepG2 0.41558 -1.26679 0.88956 1 DataSet_02_118
GBP3 RBM25 shRNA Liver HepG2 6.85 2.7761 0.01502 0.0493 DataSet_02_119
GBP3 PTBP1 shRNA Liver HepG2 8.525 3.0917 0.00033 0.00591 DataSet_02_120
GBP3 FUS shRNA Liver HepG2 3.42593 1.77649 0.05459 0.18219 DataSet_02_124
GBP3 HNRNPLL shRNA Liver HepG2 0.46479 -1.10535 0.07483 0.12938 DataSet_02_125
GBP3 SNRNP70 shRNA Liver HepG2 1.82042 0.86427 0.28365 0.39903 DataSet_02_126
GBP3 PRPF4 shRNA Liver HepG2 1.54717 0.62963 0.1278 0.23267 DataSet_02_128
GBP3 RBM17 shRNA Haematopoietic_and_lymphoid_tissue K562 2 1 0.79099 0.90706 DataSet_02_138
GBP3 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 3.16667 1.66297 0.24424 0.47691 DataSet_02_144
GBP3 DROSHA shRNA Haematopoietic_and_lymphoid_tissue K562 3.4 1.76553 0.44821 0.70906 DataSet_02_145
GBP3 FIP1L1 shRNA Haematopoietic_and_lymphoid_tissue K562 3.1 1.63227 0.37287 0.52071 DataSet_02_147
GBP3 RBM39 shRNA Haematopoietic_and_lymphoid_tissue K562 3.2 1.67807 0.05181 0.2561 DataSet_02_151
GBP3 ILF2 shRNA Haematopoietic_and_lymphoid_tissue K562 2 1 0.10434 0.38683 DataSet_02_152
GBP3 GTF2F1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.35714 -1.48543 0.01011 0.75941 DataSet_02_157
GBP3 HNRNPL shRNA Haematopoietic_and_lymphoid_tissue K562 19 4.24793 0.007 0.11802 DataSet_02_160
GBP3 SUB1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.92857 0.94753 0.09192 0.72081 DataSet_02_161
GBP3 AGO1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.21875 -2.19265 0.03261 0.53443 DataSet_02_162
GBP3 U2AF2 shRNA Haematopoietic_and_lymphoid_tissue K562 2.55172 1.35147 0.54318 0.65509 DataSet_02_170
GBP3 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.65517 -0.61005 0.25457 0.46021 DataSet_02_171
GBP3 ZFX siRNA Prostate C4-2B 0.57895 -0.7885 0.20092 0.30423 DataSet_02_172
GBP3 MXI1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.91667 0.9386 0.79044 1 DataSet_02_173
GBP3 NFE2L2 siRNA Haematopoietic_and_lymphoid_tissue K562 0.08333 -3.58496 0.00624 1 DataSet_02_174
GBP3 LMNA siRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.22625 1 DataSet_02_175
GBP3 CEBPZ siRNA Haematopoietic_and_lymphoid_tissue K562 0.47222 -1.08246 0.9971 1 DataSet_02_176
GBP3 TBL1XR1 siRNA Haematopoietic_and_lymphoid_tissue K562 2.47059 1.30485 0.48311 1 DataSet_02_178
GBP3 ZMIZ1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.33333 -1.58496 0.48607 1 DataSet_02_181
GBP3 STAT5A siRNA Haematopoietic_and_lymphoid_tissue K562 5.8 2.53605 0.9732 1 DataSet_02_182
GBP3 MAFK siRNA Haematopoietic_and_lymphoid_tissue K562 0.16129 -2.63227 0.04967 1 DataSet_02_183
GBP3 KAT2B siRNA Haematopoietic_and_lymphoid_tissue K562 0.35294 -1.5025 0.10169 1 DataSet_02_184
GBP3 CHD1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.45 -1.152 0.50579 1 DataSet_02_187
GBP3 BACH1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.19444 -2.36257 0.14483 1 DataSet_02_188
GBP3 MAFG siRNA Haematopoietic_and_lymphoid_tissue K562 0.16667 -2.58496 0.10682 1 DataSet_02_189
GBP3 RAD21 siRNA Haematopoietic_and_lymphoid_tissue K562 0.29167 -1.77761 0.45926 1 DataSet_02_190
GBP3 LMNB2 siRNA Haematopoietic_and_lymphoid_tissue K562 0.33333 -1.58496 0.13861 1 DataSet_02_191
GBP3 MAX siRNA Haematopoietic_and_lymphoid_tissue K562 0.41667 -1.26303 0.06954 1 DataSet_02_192
GBP3 ARID3A siRNA Haematopoietic_and_lymphoid_tissue K562 1.61364 0.69032 0.28209 1 DataSet_02_193
GBP3 LMNB1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.58333 0.66297 0.84436 1 DataSet_02_195
GBP3 CDAN1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.41667 -1.26303 0.0734 1 DataSet_02_197
GBP3 UBTF siRNA Haematopoietic_and_lymphoid_tissue K562 6.55556 2.71272 0.04037 1 DataSet_02_198
GBP3 ZNF384 siRNA Haematopoietic_and_lymphoid_tissue K562 2.11765 1.08246 0.92995 1 DataSet_02_203
GBP3 E2F6 siRNA Haematopoietic_and_lymphoid_tissue K562 0.08333 -3.58496 0.03567 1 DataSet_02_205
GBP3 ARID2 CRISPR Liver JHH4 0.652485 -0.615983 0.647545317381393 1 DataSet_03_015
GBP3 BCL6 siRNA Mammary_gland MCF7 2.45186 1.29388 0.0539505930404102 0.989541443114508 DataSet_03_024
GBP3 BRCA1 siRNA Mammary_gland MCF7 0.478689 -1.06284 0.0982290808387011 0.999850583334387 DataSet_03_028
GBP3 CCNA2 siRNA Mammary_gland MCF7 1.53503 0.618265 0.301449125836519 0.881144737092661 DataSet_03_034
GBP3 CENPF siRNA Mammary_gland MCF7 1.8194 0.863464 0.164275431533679 0.999662524742916 DataSet_03_052
GBP3 CHEK1 siRNA Mammary_gland MCF7 1.64436 0.717523 0.236983277550231 0.999587656258211 DataSet_03_053
GBP3 CIC CRISPR Embryo_kidney HEK293a 1.67894 0.747548 0.0517419282821087 0.999983353971111 DataSet_03_054
GBP3 CTNNB1 siRNA Mammary_gland MCF7 2.55532 1.3535 0.0462794627006257 0.999436862066063 DataSet_03_058
GBP3 E2F1 siRNA Mammary_gland MCF7 2.46403 1.30102 0.0529665927841121 0.999927373439084 DataSet_03_061
GBP3 E2F5 siRNA Mammary_gland MCF7 1.74112 0.800014 0.192936074270655 0.999540347732068 DataSet_03_062
GBP3 FLI1 siRNA Haematopoietic_and_lymphoid_tissue THP-1 1.71833 0.781007 0.0100033009470444 0.214207227103099 DataSet_03_078
GBP3 FOS siRNA Mammary_gland MCF7 0.647214 -0.627686 0.29475365112209 0.999966427400474 DataSet_03_079
GBP3 FOXC1 siRNA Mammary_gland MCF7 0.525198 -0.929067 0.138860969550705 0.999669928105298 DataSet_03_084
GBP3 FOXO1 siRNA Skin primary human dermal lymphatic endothelial cells 0.582123 -0.780603 - - DataSet_03_096
GBP3 GATA2 siRNA Lymph Lymphatic endothelial cells 2.13233 1.09243 1.71098564572229e-06 6.1072524178207e-05 DataSet_03_101
GBP3 HDAC3 siRNA Mammary_gland MCF7 2.04478 1.03195 0.106431620027661 0.99997791025972 DataSet_03_114
GBP3 HDAC5 siRNA Mammary_gland MCF7 1.7168 0.779721 0.203028114120374 0.999966625300244 DataSet_03_115
GBP3 HNF4a siRNA Liver HepG2 3.11806 1.64065 0.0806276851938023 0.691255694312614 DataSet_03_126
GBP3 HOXB7 siRNA Mammary_gland MCF7 0.589483 -0.762477 0.21197618578674 0.999977683706165 DataSet_03_127
GBP3 HSF2 siRNA Mammary_gland MCF7 1.80482 0.851859 0.169203284781459 0.990969613280381 DataSet_03_130
GBP3 IRF4 siRNA Skin Cutaneous T cell lymphoma HuT-102 cells 2.79899 1.48491 0.018947966132013 0.657309041386197 DataSet_03_134
GBP3 Klf4 siRNA Skin Primary neonatal keratinocytes 7.91958 2.98542 5.7933492724341e-06 0.000550460326466311 DataSet_03_147
GBP3 MAF siRNA Lymph Lymphatic endothelial cells 1.53937 0.622341 0.211164171892235 0.829600896648468 DataSet_03_154
GBP3 MITF siRNA Skin MZ7 1.8156 0.860445 0.000498032740258504 0.00371121385227133 DataSet_03_165
GBP3 MITF siRNA Skin Ma-Mel-15 1.52222 0.60618 0.10850674915958 0.541534546956718 DataSet_03_166
GBP3 MTA2 siRNA Stomach SGC-7901 1.53771 0.620784 - - DataSet_03_169
GBP3 MYC siRNA Colon HT29 3.27323 1.71071 - - DataSet_03_177
GBP3 MYC siRNA Central_nervous_system DAOY M2.1 5.74643 2.52267 4.01316970740968e-11 7.54774616267242e-08 DataSet_03_178
GBP3 MYC siRNA Mammary_gland MCF7 1.53631 0.619472 0.300584834754321 0.999887767096734 DataSet_03_182
GBP3 NCOR2 siRNA Mammary_gland MCF7 0.637514 -0.649471 0.279745255307619 0.999834929103349 DataSet_03_193
GBP3 NFKB1 siRNA Central_nervous_system U251 0.549524 -0.863746 0.0082973397582448 0.045560283422449 DataSet_03_197
GBP3 NMI siRNA Mammary_gland MCF7 0.514535 -0.958659 0.128664439893737 0.718075264009716 DataSet_03_199
GBP3 NR4A3 siRNA Pancreas 1.1B4 1.65586 0.727584 1.80497405990725e-05 0.000227492267671517 DataSet_03_203
GBP3 PAX3 siRNA Mammary_gland MCF7 0.581439 -0.782299 0.137747447812571 0.919978041032696 DataSet_03_206
GBP3 PCNA siRNA Mammary_gland MCF7 2.70574 1.43603 0.0374871996772024 0.999448838103647 DataSet_03_210
GBP3 PHB shRNA Embryo Embryonic stem cells (ESCs) 15.4983 3.95403 0.000238985745365538 0.00214597425205772 DataSet_03_211
GBP3 RB1 siRNA Mammary_gland MCF7 1.77081 0.82441 0.181410671683659 0.999890290262508 DataSet_03_219
GBP3 RBL2 siRNA Mammary_gland MCF7 3.6406 1.86418 0.0131006203282153 0.999927471951507 DataSet_03_220
GBP3 RELA siRNA Fibroblasts WI38 0.640443 -0.642857 4.59735067477591e-08 6.50806321095957e-06 DataSet_03_223
GBP3 RELB siRNA Immortalized_keratinocyte HaCaT 1.70358 0.768571 0.0108504172680059 0.061048152570332 DataSet_03_227
GBP3 SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 0.467456 -1.0971 - - DataSet_03_246
GBP3 SOX9 knockdown Liver HepG2 1.79048 0.840349 2.34385042081641e-06 0.000351429919001465 DataSet_03_248
GBP3 SP1 siRNA Cervix HeLa 4.30302 2.10535 7.35031369108202e-06 0.00038262269947207 DataSet_03_249
GBP3 STAT3 CRISPR Embryo hESC 0.0433624 -4.52741 0.0426847695473901 0.115593735433079 DataSet_03_258
GBP3 STAT5B siRNA Mammary_gland MCF7 1.99724 0.998005 0.116219795984606 0.999932708473107 DataSet_03_263
GBP3 TCEA1 siRNA Mammary_gland MCF7 2.07872 1.05569 0.100069504531823 0.999762252994287 DataSet_03_266
GBP3 TFAP2C siRNA Mammary_gland MCF7 15.4431 3.94889 0.000139328320265551 0.155242545857633 DataSet_03_274
GBP3 TP53 siRNA Mammary_gland MCF7 1.8899 0.918311 0.142755203470359 0.999938217444253 DataSet_03_277
GBP3 TP63 siRNA Foreskin Neonatal foreskin keratinocytes 2.70052 1.43324 0.0124125843019608 0.729684006943091 DataSet_03_282
GBP3 TWIST1 siRNA Bone_marrow MSCs 0.298035 -1.74645 - - DataSet_03_283
GBP3 ZNF746 siRNA Colon HCT116 1.59218 0.671 - - DataSet_03_293
GBP3 ZNF750 siRNA Skin Primary neonatal keratinocytes 3.82473 1.93536 0.000320420360269759 0.0219241064382946 DataSet_03_294
GBP3 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 4.28571 2.09954 0.239239902539874 0.714787127057324 DataSet_04_001
GBP3 MARK2 shRNA Haematopoietic_and_lymphoid_tissue K562 1.78571 0.836501 0.0441830185773145 0.0826372612768098 DataSet_04_012
GBP3 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 47.1226 5.55835 0.0165480792706028 0.0678340950257938 DataSet_04_014
GBP3 YBX1 CRISPR Haematopoietic_and_lymphoid_tissue K562 4.6 2.20163 0.0400860268694883 0.496278363481095 DataSet_04_022
GBP3 CIZ1 CRISPR Liver HepG2 1.77049 0.82415 0.136622438387148 0.368932399993612 DataSet_04_026
GBP3 E4F1 CRISPR Liver HepG2 1.5303 0.613817 0.158647336219414 0.44504228689668 DataSet_04_028
GBP3 FUBP1 shRNA Liver HepG2 0.641026 -0.641546 0.111321137613408 0.482037978611271 DataSet_04_030
GBP3 NFX1 CRISPR Liver HepG2 0.511111 -0.968291 0.0932019161796483 0.160368526090392 DataSet_04_032
GBP3 PAN2 CRISPR Liver HepG2 1.93478 0.952172 0.0073985003477811 0.0991806726822287 DataSet_04_033
GBP3 SMAD4 CRISPR Liver HepG2 1.52672 0.610433 0.0275413965548877 0.130173306476473 DataSet_04_035
GBP3 SMAD5 CRISPR Liver HepG2 1.54348 0.626185 0.0860424500127359 0.473429619305688 DataSet_04_036
GBP3 ZC3H8 shRNA Liver HepG2 1.74444 0.802768 0.427997383940184 0.606417723583473 DataSet_04_040
GBP3 PAN2 CRISPR Liver HepG2 1.52672 0.610433 0.0170921650500422 0.0798507330917231 DataSet_04_066
GBP3 SEPT11 CRISPR Liver HepG2 0.504951 -0.985786 0.281299831173827 0.547300580425805 DataSet_04_068
GBP3 ABT1 shRNA Liver HepG2 3.66667 1.87447 0.000538367642954545 0.00588371093336557 DataSet_04_052
GBP3 CALR shRNA Liver HepG2 2.35165 1.23367 0.0108281043872661 0.0391122103143589 DataSet_04_053
GBP3 CCAR1 shRNA Liver HepG2 4.74775 2.24724 0.00356446194789695 0.0280073342273165 DataSet_04_054
GBP3 CNOT7 shRNA Liver HepG2 5.73134 2.51887 0.000770766568046094 0.00593549940647443 DataSet_04_051
GBP3 DDX1 shRNA Liver HepG2 2.08974 1.06333 0.0263887313374 0.157058973810952 DataSet_04_057
GBP3 NPM1 shRNA Liver HepG2 1.85926 0.894728 0.0906937404035366 0.451431378863691 DataSet_04_058
GBP3 PRPF6 shRNA Liver HepG2 2.26606 1.18018 0.0418052233970902 0.155875031523388 DataSet_04_056
GBP3 YBX3 shRNA Liver HepG2 0.416667 -1.26303 0.0587813522039874 0.182652861615406 DataSet_02_98
GBP3 ACTN4 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.57143 0.652077 0.579414184058898 0.761121519680488 DataSet_04_048
GBP3 DDX17 CRISPR Haematopoietic_and_lymphoid_tissue K562 3.2 1.67807 0.360567398921134 0.811074794715046 DataSet_04_047
GBP3 DDX20 CRISPR Haematopoietic_and_lymphoid_tissue K562 10 3.32193 0.35175766421279 0.719045144296139 DataSet_04_050
GBP3 NPM1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.636364 -0.652077 0.660482891095504 0.810729250262248 DataSet_04_046
GBP3 SMG5 CRISPR Haematopoietic_and_lymphoid_tissue K562 7.33333 2.87447 0.279424687198299 0.661374086785901 DataSet_04_073
GBP3 SMG7 CRISPR Haematopoietic_and_lymphoid_tissue K562 3.66667 1.87447 0.577987978995935 0.84504174244553 DataSet_04_075
GBP3 SNW1 CRISPR Haematopoietic_and_lymphoid_tissue K562 6 2.58496 0.165771234132268 0.301139700108946 DataSet_04_049
GBP3 CITED2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.64151 1.40136 0.0246646420334542 0.166094384179584 DataSet_02_38
GBP3 DPF2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.0943396 -3.40599 0.0724402864957183 0.157438761677762 DataSet_02_14
GBP3 ERF CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.471698 -1.08406 0.358171471783865 0.537152865627308 DataSet_02_34
GBP3 HMGA1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 18.5 4.20945 0.0214573427489174 0.3937702583054 DataSet_02_75
GBP3 HMGN3 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.566038 -0.82103 0.514619828481702 0.85586972457874 DataSet_02_45
GBP3 LDB1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.90566 0.930291 0.144935509623269 0.276220864916514 DataSet_02_35
GBP3 NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.62264 0.698344 0.583421229836262 0.768658389372334 DataSet_02_32
GBP3 TBL1XR1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.66038 0.731511 0.414003643218241 0.603071380115249 DataSet_02_43
GBP3 TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.54717 0.629632 0.254759439877428 0.400706025744237 DataSet_02_33
GBP3 TLE2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.88679 1.52947 0.0734101870929089 0.180803935359814 DataSet_02_53
GBP3 CNOT7 shRNA Haematopoietic_and_lymphoid_tissue K562 45 5.49185 0.0490154977247307 0.169148243792579 DataSet_04_061
GBP3 HDGF shRNA Haematopoietic_and_lymphoid_tissue K562 0.333333 -1.58496 0.202651832732353 0.313452771837589 DataSet_04_059
GBP3 PRPF6 shRNA Haematopoietic_and_lymphoid_tissue K562 1.92857 0.947533 0.473372014316119 0.793187325032946 DataSet_04_065
GBP3 UBE2L3 shRNA Haematopoietic_and_lymphoid_tissue K562 3.4 1.76553 0.192142490877084 0.434869130164501 DataSet_04_062
GBP3 SMARCA4 siRNA Colon HCT116 1.513 0.59741 3.322653e-01 9.892536e-01 DataSet_03_301
GBP3 SMARCA4 siRNA Colon HCT116 0.420877 -1.24853 4.157648e-02 0.2052143 DataSet_03_302
GBP3 ELF3 CRISPR Bile_duct HBDEC2 0.590065 -0.761055 4.120114e-04 3.202188e-03 DataSet_03_304
GBP3 SNAI2 shRNA Pancreas pancreatic cancer stem cells 1.53867 0.621689 3.516680e-02 0.6330193 DataSet_03_306
GBP3 SNAI2 shRNA Pancreas KLM1 1.5001 0.585059 3.858045e-02 0.27048869 DataSet_03_307
GBP3 PRMT1 shRNA Lung A549 3.29869 1.72189 - - DataSet_03_342
GBP3 ACTR5 siRNA Muscle RD 0.640717 -0.642241 - - DataSet_03_343
GBP3 INO80 siRNA Muscle RD 1.7201 0.782489 - - DataSet_03_344
GBP3 LITAF siRNA Lymph KARPAS-231 1.56497 0.646136 4.659502e-03 0.33241110 DataSet_03_309
GBP3 EZH2 knockdown Colon HCT116 1.72139 0.783575 0.159150027 0.8558365 DataSet_03_334
GBP3 ZFX siRNA Prostate C4-2B 0.662066 -0.594952 2.024755e-01 2.689073e-01 DataSet_03_348
GBP3 SKI CRISPR Blood HL60 2.08243 1.05826 3.238548e-03 0.112116528 DataSet_03_351
GBP3 ESR1 siRNA Mammary_gland MCF7 0.370697 -1.43169 1.559252e-04 0.0102919612 DataSet_03_352
GBP3 ETV5 knockdown Colon HT29 0.484127 -1.04654 3.969162e-03 0.077464360 DataSet_03_353
GBP3 TET1 CRISPR Mammary_gland Hs578T 2.36646 1.24273 3.646014e-03 2.521436e-02 DataSet_03_355
GBP3 TP53 CRISPR Brain U5-NPC 1.93086 0.949244 3.551229e-02 1.696555e-01 DataSet_03_358
GBP3 RUNX1 shRNA Haematopoietic_and_lymphoid_tissue OCI-AML5 2.17478 1.12087 3.718500e-02 2.206681e-01 DataSet_03_359
GBP3 EP300 shRNA Mammary_gland MCF10AT 0.608454 -0.71678 1.346220e-02 0.087985774 DataSet_03_364
GBP3 ZNF148 shRNA Mammary_gland MDA-MB-231 1.7008 0.76621 6.783889e-04 0.024865395 DataSet_03_366
GBP3 ABL1 shRNA Liver HuH7 1.8523 0.889319 1.299331e-04 0.0018382020 DataSet_03_367
GBP3 DNMT3A knockout Embryo_kidney HEK293T 0.485122 -1.04358 - - DataSet_03_369
GBP3 ZFP36L1 siRNA Urinary_bladder J82 2.65429 1.40832 - - DataSet_03_371
GBP3 BHLHE40 shRNA Cervix HeLaS3 5.29358 2.40424 4.536409e-01 0.89208548 DataSet_03_372
GBP3 E2F1 siRNA Nasopharynx HK1 3.86651 1.95103 4.850645e-05 2.486414e-03 DataSet_03_373
GBP3 ZBTB7A siRNA Stomach BGC823 0.59081 -0.759233 - - DataSet_03_380
GBP3 NFKB2 siRNA Bone_marrow U2OS 1.88579 0.91517 5.804659e-03 0.10815471 DataSet_03_381
GBP3 DNMT1 siRNA Skin Human melanoma cells 1.92581 0.945469 9.394152e-04 2.996098e-03 DataSet_03_382
GBP3 YY1 shRNA Brain GSC1517 9 3.16992 - - DataSet_03_384
GBP3 NFKBIA shRNA Bone_marrow U2OS 0.650131 -0.621198 3.564027e-01 0.87005461 DataSet_03_389
GBP3 ILF2 siRNA Stomach SGC-7901 2.05152 1.03669 0.1886487208 0.37277664 DataSet_03_393
GBP3 BMI1 shRNA Bile_duct QBC-939 1.95768 0.969144 1.697576e-04 0.0026258977 DataSet_03_395
GBP3 RELA CRISPR Brain T30 1.62784 0.702954 0.3719753203 0.8400824 DataSet_03_399
GBP3 EHF shRNA Stomach MKN7 418.771 8.71002 - - DataSet_03_402
GBP3 CHD1 shRNA Prostate LNCaP 0.211752 -2.23956 6.458839e-04 4.507419e-02 DataSet_03_407
GBP3 MAP3K7 shRNA Prostate LNCaP 0.484764 -1.04464 1.263150e-01 3.393149e-01 DataSet_03_408
GBP3 USP22 shRNA Liver HuH7 17.6476 4.1414 - - DataSet_03_411
GBP3 E2F6 shRNA Liver HuH7 0.515197 -0.956803 - - DataSet_03_412
GBP3 E2F2 siRNA Prostate LNCaP 1.92145 0.942195 1.359498e-02 7.966320e-02 DataSet_03_414
GBP3 ZKSCAN3 CRISPR Colon HCT116 0.149573 -2.74108 3.291260e-02 0.359801871 DataSet_03_415
GBP3 MAEL CRISPR Liver Alexander cells 0.148148 -2.75489 - - DataSet_03_423
GBP3 USP7 shRNA Skin xenograft cells 0.501716 -0.995056 0.29486378 0.4409976 DataSet_03_431
GBP3 PLAG1 shRNA Cord_blood Lin-CD34+ HSPCs 0.531496 -0.911869 - - DataSet_03_432
GBP3 POU2AF1 CRISPR Haematopoietic_and_lymphoid_tissue OCI-Ly7 2.579 1.36681 6.676749e-03 0.270467188 DataSet_03_434
GBP3 POU2AF1 CRISPR Lymph SUDHL4 6.50162 2.7008 5.651409e-03 0.028721719 DataSet_03_435
GBP3 SUFU shRNA Mammary_gland HCC1954 cells 0.304779 -1.71416 0.0951706366 0.6407192 DataSet_03_437
GBP3 FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 2.92308 1.54749 8.483825e-02 0.90558273 DataSet_03_439
GBP3 SETDB1 shRNA Colon HCT116 4.26241 2.09167 - - DataSet_03_440
GBP3 PHF14 siRNA Mammary_gland MDA-MB-231 0.612856 -0.706381 0.0156238174 0.3130938 DataSet_03_443
GBP3 PURA siRNA Cervix HeLa 2.74632 1.4575 2.027527e-03 0.054304060 DataSet_03_444
GBP3 CBX2 siRNA Mammary_gland MDA-MB-231 1.5961 0.674553 1.490177e-03 1.205475e-02 DataSet_03_450
GBP3 SMARCA2 shRNA Lung HCC2302 2.35645 1.23662 2.856365e-05 5.606433e-05 DataSet_03_455
GBP3 IRF2 shRNA Cord_Blood CD34+ cells 1.94792 0.961932 - - DataSet_03_460
GBP3 TXNIP shRNA Cord_Blood CD34+ cells 4.04673 2.01676 - - DataSet_03_461
GBP3 TXNIP shRNA Cord_blood ST3 3.2027 1.67929 3.459452e-02 0.2576679995 DataSet_03_462
GBP3 SOX9 knockout Liver HuH7 2.28571 1.19265 1.022792e-03 9.150396e-03 DataSet_03_463
GBP3 PARP1 knockout Embryo_kidney HEK293a 0.526914 -0.92436 8.149754e-02 1.730266e-01 DataSet_03_464
GBP3 STAT3 shRNA Liver HepG2 4.89583 2.29155 1.838613e-04 0.0155583327 DataSet_03_465
GBP3 EZH2 siRNA Prostate LNCaP 1.80754 0.854032 - - DataSet_03_472
GBP3 EZH2 siRNA Umbilical_vein HUVEC 0.537084 -0.896779 4.146803e-04 0.047194117 DataSet_03_473
GBP3 CHCHD3 CRISPR Haematopoietic_and_lymphoid_tissue K562 4.5 2.16992 0.04570411 0.8431706 DataSet_04_071
GBP3 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 4.28571 2.09954 0.2790141 0.7209135 DataSet_04_072
GBP3 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 2.9 1.53605 0.3054809 0.465493098 DataSet_04_074
Regulation Region
 
T(co)Fs that significantly regulate CNOT7 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of GBP3
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines