Gene Overview
Target Gene: CYP1A1
NCBI Official Symbol: CYP1A1
Entrez ID: 1543
Ensembl ID: ENSG00000140465
Gene Full Name: cytochrome P450 family 1 subfamily A member 1
Strand: -
Gene Locus: 15q24.1
External Links:

CYP1A1 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate CYP1A1   
T(co)Fs that Repress CYP1A1
The Intensity of the Gene Regulated by T(co)Fs:
CYP1A1-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
CYP1A1 HNF1B shRNA Ovary RMG2 2.12571 1.08794 0.00098 0.00414 DataSet_01_103
CYP1A1 FOXA1 siRNA Prostate LNCaP 1.51985 0.60393 - - DataSet_01_104
CYP1A1 HOXA1 siRNA Lung_fibroblast IMR-90 4.67594 2.22526 0.01466 0.1288 DataSet_01_110
CYP1A1 ID1 siRNA Lung A549 1.87849 0.90957 0.24826 0.48509 DataSet_01_117
CYP1A1 ID1 siRNA Lung H1650 0.07005 -3.83549 0.00088 0.32206 DataSet_01_118
CYP1A1 GATA3 siRNA Mammary_gland MCF7 2.19337 1.13315 0.04933 0.1944 DataSet_01_120
CYP1A1 ZIC2 siRNA Pancreas PANC1 28.4876 4.83226 - - DataSet_01_121
CYP1A1 FOXM1 siRNA Central_nervous_system U87 0.38899 -1.3622 - - DataSet_01_122
CYP1A1 ZNF43 siRNA Gastrointestinal_tissue GIST-T1 0.58343 -0.77736 6.60556e-05 0.00547 DataSet_01_125
CYP1A1 ZNF254 siRNA Gastrointestinal_tissue GIST-T1 0.3559 -1.49045 2.66102e-07 0.00016 DataSet_01_127
CYP1A1 ZNF665 siRNA Gastrointestinal_tissue GIST-T1 0.65674 -0.6066 0.00043 0.00948 DataSet_01_129
CYP1A1 ZNF708 siRNA Gastrointestinal_tissue GIST-T1 0.50129 -0.99629 8.72331e-06 0.00139 DataSet_01_130
CYP1A1 SPDEF shRNA Mammary_gland MCF7 4.03276 2.01177 1.15413e-06 0.00251 DataSet_01_135
CYP1A1 POLR3A siRNA Mammary_gland MCF7 3.06202 1.61448 - - DataSet_01_139
CYP1A1 GLI2 siRNA Bone_marrow U2OS 0.57869 -0.78914 - - DataSet_01_143
CYP1A1 EHF siRNA Corneal_epithelial Corneal epithelial cells 0.6015 -0.73336 2.09597e-05 0.00229 DataSet_01_147
CYP1A1 STAT1 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 2.075 1.05311 0.29814 0.6071 DataSet_01_154
CYP1A1 ELK1 siRNA Peripheral_blood CD4+ T cells 0.18748 -2.41516 5.92322e-06 0.00061 DataSet_01_162
CYP1A1 JUN siRNA Peripheral_blood CD4+ T cells 0.1759 -2.50721 4.7759e-06 0.00077 DataSet_01_164
CYP1A1 MAF siRNA Peripheral_blood CD4+ T cells 0.18127 -2.46378 1.15138e-05 0.00173 DataSet_01_165
CYP1A1 NFATC3 siRNA Peripheral_blood CD4+ T cells 0.20121 -2.31321 1.95148e-05 0.00356 DataSet_01_166
CYP1A1 HOXB7 siRNA Pancreas MIA PaCa-2 0.65092 -0.61944 0.08872 0.62609 DataSet_01_169
CYP1A1 HSF1 shRNA Liver KYN2 3.87025 1.95243 - - DataSet_01_178
CYP1A1 STAT3 siRNA Oesophagus OE21 0.66535 -0.58781 0.23344 0.76137 DataSet_01_180
CYP1A1 NR5A2 siRNA Mammary_gland MCF7 1.95652 0.96829 4.74549e-07 8.15588e-05 DataSet_01_182
CYP1A1 TP63 shRNA Bladder UC14 2.33331 1.22238 1.41249e-05 0.00039 DataSet_01_183
CYP1A1 GATA2 siRNA Prostate LNCaP 3.20393 1.67984 0.00312 0.01407 DataSet_01_193
CYP1A1 CREB1 shRNA Parotid_gland H3118 MEC 7.75754 2.9556 0.00093 0.10095 DataSet_01_194
CYP1A1 CREB1 shRNA Parotid_gland HSY 0.61525 -0.70076 0.21561 0.88214 DataSet_01_195
CYP1A1 TP63 siRNA Immortalized_keratinocyte HaCaT RG 4.12786 2.04539 - - DataSet_01_196
CYP1A1 TP63 siRNA Head_and_neck SCC-1 0.64847 -0.62488 - - DataSet_01_198
CYP1A1 TP63 siRNA Head_and_neck SCC-6 0.54928 -0.8644 - - DataSet_01_202
CYP1A1 XBP1 shRNA Mammary_gland T47D 2.7595 1.46441 2.20561e-06 0.00023 DataSet_01_203
CYP1A1 MITF shRNA Skin COLO829 2.38516 1.25408 0.00367 0.04827 DataSet_01_207
CYP1A1 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly10 0.45201 -1.14558 - - DataSet_01_208
CYP1A1 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 0.5082 -0.97653 - - DataSet_01_210
CYP1A1 LIN28A siRNA Embryo H9 3.00666 1.58816 7.55732e-05 0.00256 DataSet_01_215
CYP1A1 ATM shRNA Mammary_gland MCF10A 0.36519 -1.45328 2.27497e-06 4.58869e-05 DataSet_01_219
CYP1A1 SNAI2 shRNA Skin Primary human keratinocytes 3.53837 1.82309 0.00027 0.01025 DataSet_01_225
CYP1A1 KLF2 shRNA Bone_marrow RPMI8226 9.84077 3.29877 0.04053 0.59735 DataSet_01_226
CYP1A1 FOXA1 siRNA Prostate LNCaP 1.69227 0.75896 0.06239 0.33696 DataSet_01_233
CYP1A1 ARNT shRNA Embryo hESC HSF1 0.60295 -0.72989 0.75501 0.99999 DataSet_01_240
CYP1A1 TWIST1 shRNA Stomach CAF14 1.7074 0.7718 0.31938 0.99996 DataSet_01_252
CYP1A1 TWIST1 shRNA Stomach CAF32 0.18943 -2.40024 0.00058 0.01678 DataSet_01_253
CYP1A1 TWIST1 shRNA Stomach CAF 0.56872 -0.81422 0.34888 0.76841 DataSet_01_254
CYP1A1 YBX1 shRNA Mammary_gland MDA 2.24541 1.16698 0.20271 0.42339 DataSet_01_257
CYP1A1 SIX4 siRNA Ovary PEO1 3.76479 1.91257 1.85866e-05 0.0016 DataSet_01_269
CYP1A1 ESRRA shRNA Embryo_kidney 293T 0.54007 -0.88878 0.0056 0.48291 DataSet_01_280
CYP1A1 MSX1 siRNA Tooth Dental Pulp Cells 2.48424 1.31281 0.0195 0.05056 DataSet_01_281
CYP1A1 ZIC5 siRNA Skin A375 6.01777 2.58923 - - DataSet_01_284
CYP1A1 ZIC5 siRNA Skin SK-MEL-28 2.09519 1.06708 - - DataSet_01_285
CYP1A1 POSTN shRNA Brain GSC272 2.22851 1.15608 0.08565 0.54319 DataSet_01_293
CYP1A1 TFAP4 siRNA Brain BE(2)-C 0.09419 -3.40829 0.15304 0.51625 DataSet_01_295
CYP1A1 ELK3 shRNA Mammary_gland MDA-MB-231 0.46813 -1.09501 1e-04 0.00061 DataSet_01_318
CYP1A1 MYC siRNA Colon HCT116 1.57615 0.6564 0.00361 0.00875 DataSet_01_324
CYP1A1 TP63 shRNA Head_and_neck JHU-029 1.65068 0.72306 0.00018 0.01327 DataSet_01_326
CYP1A1 TP63 shRNA Head_and_neck JHU-029 1.65068 0.72306 0.00018 0.01327 DataSet_01_329
CYP1A1 KLF4 siRNA Embryo HCE 1.98824 0.99149 8.74554e-05 0.03669 DataSet_01_339
CYP1A1 KLF7 siRNA Embryo HCE 0.52152 -0.93922 0.26311 0.65386 DataSet_01_340
CYP1A1 HIF1A siRNA Oral_cavity OEC-M1 1.77316 0.82632 0.05353 0.85151 DataSet_01_348
CYP1A1 ZNF24 siRNA Embryo_kidney HEK293 0.63464 -0.656 - - DataSet_01_353
CYP1A1 CDX2 siRNA Colon COLO320 2.22587 1.15437 - - DataSet_01_357
CYP1A1 PAX3 shRNA Soft_tissue Rh30 1.66809 0.7382 - - DataSet_01_359
CYP1A1 SOX17 siRNA Umbilical_vein HUVEC 0.60381 -0.72783 - - DataSet_01_360
CYP1A1 SAFB2 shRNA Liver HepG2 2.35786 1.23748 0.02071 0.06014 DataSet_02_102
CYP1A1 FIP1L1 shRNA Liver HepG2 0.59062 -0.7597 0.07824 0.14822 DataSet_02_103
CYP1A1 TAF15 shRNA Liver HepG2 0.28671 -1.80232 0.00117 0.01179 DataSet_02_106
CYP1A1 ZNF622 shRNA Liver HepG2 1.60141 0.67934 0.05584 0.09738 DataSet_02_108
CYP1A1 HNRNPUL1 shRNA Liver HepG2 2.11706 1.08206 0.03694 0.08671 DataSet_02_109
CYP1A1 RBM39 shRNA Liver HepG2 0.36772 -1.4433 0.00354 0.21042 DataSet_02_111
CYP1A1 BCLAF1 shRNA Liver HepG2 1.97826 0.98423 0.00124 0.02531 DataSet_02_112
CYP1A1 U2AF2 shRNA Liver HepG2 0.54894 -0.86527 0.44581 0.58939 DataSet_02_113
CYP1A1 PCBP1 shRNA Liver HepG2 0.51981 -0.94393 0.00037 0.01339 DataSet_02_115
CYP1A1 SUB1 shRNA Liver HepG2 1.5931 0.67184 0.12746 0.30438 DataSet_02_117
CYP1A1 RBM25 shRNA Liver HepG2 0.25641 -1.96347 0.00171 0.0227 DataSet_02_119
CYP1A1 PTBP1 shRNA Liver HepG2 0.28089 -1.83194 8.30521e-05 0.00582 DataSet_02_120
CYP1A1 EWSR1 shRNA Liver HepG2 0.28782 -1.79679 0.00147 0.04273 DataSet_02_122
CYP1A1 SNRNP70 shRNA Liver HepG2 2.85657 1.51429 0.02813 0.08597 DataSet_02_126
CYP1A1 PRPF4 shRNA Liver HepG2 2.23415 1.15972 0.00797 0.04835 DataSet_02_128
CYP1A1 TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 4 2 0.68946 0.85519 DataSet_02_129
CYP1A1 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 4.25 2.08746 0.00014 0.02779 DataSet_02_131
CYP1A1 AGO2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.6 -0.73697 0.49592 0.64728 DataSet_02_132
CYP1A1 SRSF7 shRNA Haematopoietic_and_lymphoid_tissue K562 4 2 0.00085 0.22541 DataSet_02_133
CYP1A1 SRSF9 shRNA Haematopoietic_and_lymphoid_tissue K562 2.75 1.45943 0.00107 0.0884 DataSet_02_134
CYP1A1 HNRNPK shRNA Haematopoietic_and_lymphoid_tissue K562 2.75 1.45943 0.00125 0.14272 DataSet_02_136
CYP1A1 PCBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 3 1.58496 0.03237 0.24166 DataSet_02_137
CYP1A1 RBM17 shRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.20974 0.48905 DataSet_02_138
CYP1A1 RBM34 shRNA Haematopoietic_and_lymphoid_tissue K562 3.75 1.90689 0.0172 0.21274 DataSet_02_141
CYP1A1 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.42857 -1.22239 0.93302 0.95677 DataSet_02_143
CYP1A1 DROSHA shRNA Haematopoietic_and_lymphoid_tissue K562 6.75 2.75489 0.33183 0.63536 DataSet_02_145
CYP1A1 CCAR2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.33333 -1.58496 0.07015 0.48869 DataSet_02_146
CYP1A1 NONO shRNA Haematopoietic_and_lymphoid_tissue K562 0.46875 -1.09311 0.80663 0.8899 DataSet_02_149
CYP1A1 SAFB2 shRNA Haematopoietic_and_lymphoid_tissue K562 6.33333 2.66297 0.0651 0.4965 DataSet_02_150
CYP1A1 RBM39 shRNA Haematopoietic_and_lymphoid_tissue K562 10 3.32193 0.1368 0.3363 DataSet_02_151
CYP1A1 SRSF4 shRNA Haematopoietic_and_lymphoid_tissue K562 1.71429 0.77761 0.2488 0.54767 DataSet_02_154
CYP1A1 HNRNPUL1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.25 1.16993 0.63677 0.82847 DataSet_02_156
CYP1A1 GTF2F1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.57143 -0.80735 0.17986 0.99879 DataSet_02_157
CYP1A1 PSIP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.53333 -0.90689 0.7845 0.85554 DataSet_02_158
CYP1A1 XRCC5 shRNA Haematopoietic_and_lymphoid_tissue K562 0.38095 -1.39232 0.12079 0.68885 DataSet_02_159
CYP1A1 SUB1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.47619 -1.07039 0.70325 0.95234 DataSet_02_161
CYP1A1 U2AF1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.26316 -1.926 0.02063 0.15825 DataSet_02_165
CYP1A1 EWSR1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.21053 -2.24793 0.00796 0.22555 DataSet_02_167
CYP1A1 RBM22 shRNA Haematopoietic_and_lymphoid_tissue K562 2.5 1.32193 0.00127 0.05289 DataSet_02_168
CYP1A1 TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 0.46667 -1.09954 0.00082 0.04354 DataSet_02_169
CYP1A1 U2AF2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.57895 -0.7885 0.25358 0.38457 DataSet_02_170
CYP1A1 ZFX siRNA Prostate C4-2B 1.66933 0.73927 0.00034 0.00331 DataSet_02_172
CYP1A1 NFE2L2 siRNA Haematopoietic_and_lymphoid_tissue K562 4.42857 2.14684 0.00321 1 DataSet_02_174
CYP1A1 CEBPZ siRNA Haematopoietic_and_lymphoid_tissue K562 0.07692 -3.70044 0.00719 1 DataSet_02_176
CYP1A1 ZNF180 siRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.06125 1 DataSet_02_177
CYP1A1 VEZF1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.41176 -1.28011 0.60121 1 DataSet_02_179
CYP1A1 ATF3 siRNA Haematopoietic_and_lymphoid_tissue K562 2.71429 1.44057 0.34325 1 DataSet_02_180
CYP1A1 STAT5A siRNA Haematopoietic_and_lymphoid_tissue K562 0.61111 -0.71049 0.60518 1 DataSet_02_182
CYP1A1 CTCF siRNA Haematopoietic_and_lymphoid_tissue K562 1.8 0.848 0.32613 1 DataSet_02_185
CYP1A1 BHLHE40 siRNA Haematopoietic_and_lymphoid_tissue K562 5 2.32193 0.07089 1 DataSet_02_186
CYP1A1 CHD1 siRNA Haematopoietic_and_lymphoid_tissue K562 3.66667 1.87447 0.09934 1 DataSet_02_187
CYP1A1 BACH1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.53846 -0.89308 0.78435 1 DataSet_02_188
CYP1A1 MAFG siRNA Haematopoietic_and_lymphoid_tissue K562 0.53846 -0.89308 0.7492 1 DataSet_02_189
CYP1A1 RAD21 siRNA Haematopoietic_and_lymphoid_tissue K562 1.73333 0.79355 0.95109 1 DataSet_02_190
CYP1A1 LMNB2 siRNA Haematopoietic_and_lymphoid_tissue K562 0.42857 -1.22239 0.11206 1 DataSet_02_191
CYP1A1 MAX siRNA Haematopoietic_and_lymphoid_tissue K562 2.30769 1.20645 0.00966 1 DataSet_02_192
CYP1A1 TCP1 siRNA Haematopoietic_and_lymphoid_tissue K562 2.71429 1.44057 0.44622 1 DataSet_02_194
CYP1A1 LMNB1 siRNA Haematopoietic_and_lymphoid_tissue K562 2.76923 1.46949 0.4036 1 DataSet_02_195
CYP1A1 CDAN1 siRNA Haematopoietic_and_lymphoid_tissue K562 2.15385 1.10692 0.03716 1 DataSet_02_197
CYP1A1 MAZ siRNA Haematopoietic_and_lymphoid_tissue K562 3 1.58496 0.21791 1 DataSet_02_199
CYP1A1 E2F4 siRNA Haematopoietic_and_lymphoid_tissue K562 0.04762 -4.39232 0.0169 1 DataSet_02_200
CYP1A1 BRCA1 siRNA Haematopoietic_and_lymphoid_tissue K562 2.88889 1.53051 0.65874 1 DataSet_02_202
CYP1A1 ZNF384 siRNA Haematopoietic_and_lymphoid_tissue K562 4.33333 2.11548 0.05601 1 DataSet_02_203
CYP1A1 RCOR1 siRNA Haematopoietic_and_lymphoid_tissue K562 2.42857 1.28011 0.96747 1 DataSet_02_204
CYP1A1 ZFX siRNA Mammary_gland MCF7 7.95932 2.99265 0.03182 0.16052 DataSet_02_206
CYP1A1 AR siRNA Prostate abl cells 1.82279 0.866144 0.852263070052245 0.999852161656754 DataSet_03_004
CYP1A1 AR siRNA Prostate LNCaP 0.361702 -1.46713 0.0919831142596403 1 DataSet_03_005
CYP1A1 AR siRNA Prostate LNCaP 1.89848 0.924848 0.00331165677645506 0.00512729701984664 DataSet_03_011
CYP1A1 ARID2 CRISPR Liver JHH4 1.67113 0.740824 0.508945698792474 1 DataSet_03_015
CYP1A1 BCL6 siRNA Lymph OCI-Ly7 DLBCL 2.38895 1.25638 0.284284986105354 0.846715734253707 DataSet_03_025
CYP1A1 CASP8AP2 siRNA Bone_marrow hTERT-RPE1 4.77863 2.2566 1.79781745231504e-13 7.88298007403836e-10 DataSet_03_030
CYP1A1 CCNA2 siRNA Mammary_gland MCF7 1.71484 0.77807 0.00201796810028912 0.872422373040044 DataSet_03_034
CYP1A1 CEBPB siRNA Embryo hESC 0.258907 -1.94949 0.0456250247309729 0.358935931237773 DataSet_03_049
CYP1A1 CREBBP siRNA Mammary_gland MCF7 1.72085 0.783118 0.00194999099643689 0.963067261754673 DataSet_03_055
CYP1A1 EP300 siRNA Prostate LNCaP 0.59057 -0.759821 0.113866328346164 0.223666002108536 DataSet_03_065
CYP1A1 FHL2 siRNA Prostate LNCaP 0.525973 -0.926938 0.0465043491313855 0.56327612890306 DataSet_03_076
CYP1A1 FOXA1 siRNA Mammary_gland MCF7 1.8792 0.91012 3.60673417802611e-05 0.00105538938390898 DataSet_03_080
CYP1A1 FOXA1 siRNA Mammary_gland MCF7 2.1563 1.10856 1.41068808091224e-09 6.52070638907487e-08 DataSet_03_081
CYP1A1 FOXA1 siRNA Mammary_gland MCF7 2.1563 1.10856 1.41068808091224e-09 6.52070638907487e-08 DataSet_03_082
CYP1A1 FOXA1 siRNA Prostate LNCaP 2.77543 1.47271 2.28190538647797e-05 0.000785748356385778 DataSet_03_083
CYP1A1 FOXM1 siRNA Mammary_gland BT-20 cells 0.555556 -0.847997 0.00263678150724145 0.169673509501875 DataSet_03_091
CYP1A1 GATA2 siRNA Lymph Lymphatic endothelial cells 0.490294 -1.02828 0.00985978563115908 0.0231827413986592 DataSet_03_101
CYP1A1 GATA3 siRNA Mammary_gland MCF7 2.81446 1.49286 4.70999399001987e-05 0.254987299634701 DataSet_03_102
CYP1A1 GATA4 siRNA Stomach YCC3 0.444744 -1.16895 0.00554216149428594 0.4378992877045 DataSet_03_107
CYP1A1 HINFP siRNA Bone_marrow hTERT-RPE1 1.54701 0.629481 0.0013108391225749 0.0789527824070916 DataSet_03_122
CYP1A1 HSF2 siRNA Mammary_gland MCF7 0.649117 -0.623449 0.00619490167022875 0.990969613280381 DataSet_03_130
CYP1A1 HTATIP siRNA Prostate LNCaP 2.12904 1.0902 0.0416011383907113 0.062320771519159 DataSet_03_131
CYP1A1 KLF5 siRNA Stomach YCC3 0.407854 -1.29387 0.000776073963375875 0.0481543887590389 DataSet_03_151
CYP1A1 MAPK14 siRNA Mammary_gland MCF7 1.62453 0.700024 0.0201914996062489 0.999824418484635 DataSet_03_157
CYP1A1 MCM2 siRNA Mammary_gland MCF7 1.96994 0.978148 0.000574254028411792 0.999925560383539 DataSet_03_161
CYP1A1 MEF2D siRNA Liver HuH7 1.74908 0.806599 - - DataSet_03_163
CYP1A1 MTA2 siRNA Stomach SGC-7901 3.1486 1.65471 - - DataSet_03_169
CYP1A1 MYB siRNA Prostate VCaP 0.294975 -1.76133 9.18618657327725e-06 0.00357146548099482 DataSet_03_174
CYP1A1 MYBL2 siRNA Mammary_gland MCF7 2.15386 1.10692 0.000281864357781007 0.999907476570542 DataSet_03_176
CYP1A1 MYC siRNA Colon HT29 3.20073 1.6784 - - DataSet_03_177
CYP1A1 MYC siRNA Mammary_gland MCF7 2.13641 1.09519 0.000299914648969193 0.999887767096734 DataSet_03_182
CYP1A1 MYCN siRNA Brain NB1691 1.52511 0.608917 0.23573661870675 0.755701017438047 DataSet_03_186
CYP1A1 NPAT siRNA Bone_marrow hTERT-RPE1 2.6044 1.38095 5.04223850512032e-06 0.00374778844015904 DataSet_03_200
CYP1A1 NR2F2 siRNA Uterus Primary eutopic stromal cells 1.87529 0.907116 0.0865732701363862 0.99947668859931 DataSet_03_202
CYP1A1 NR4A3 siRNA Pancreas 1.1B4 3.95606 1.98406 1.31630404129958e-07 8.98863030169407e-06 DataSet_03_203
CYP1A1 PBX1 siRNA Mammary_gland LTED 1.55494 0.636856 0.0118028436604081 0.99990029707784 DataSet_03_208
CYP1A1 PCNA siRNA Mammary_gland MCF7 0.637237 -0.650097 0.00505384128962672 0.999448838103647 DataSet_03_210
CYP1A1 PHB shRNA Embryo Embryonic stem cells (ESCs) 0.46211 -1.11369 0.0213287552476652 0.0574613330291352 DataSet_03_211
CYP1A1 RB1 siRNA Mammary_gland MCF7 0.658546 -0.602643 0.00728437856318642 0.999890290262508 DataSet_03_219
CYP1A1 RELB siRNA Immortalized_keratinocyte HaCaT 0.421918 -1.24496 1.52491652403589e-05 0.00026703016986179 DataSet_03_227
CYP1A1 SOX11 siRNA Lung_fibroblast NHLF 4.68595 2.22834 0.145069637239744 0.557111095499226 DataSet_03_237
CYP1A1 SOX11 siRNA Lung_fibroblast NHLF 2.71219 1.43946 0.259738874821037 0.627785721703712 DataSet_03_238
CYP1A1 SOX2 siRNA Embryo 2102Ep 0.652165 -0.61669 0.000562579681694818 0.0125334139421407 DataSet_03_242
CYP1A1 SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 0.517544 -0.950247 - - DataSet_03_246
CYP1A1 SP1 siRNA Cervix HeLa 2.16679 1.11556 2.94163436009105e-05 0.000865737505247447 DataSet_03_249
CYP1A1 SP1 siRNA Ovary OVSAYO 0.344578 -1.5371 0.0154907946423582 0.160846065630841 DataSet_03_251
CYP1A1 STAT3 CRISPR Embryo hESC 2.67491 1.41949 0.092621162573938 0.177580478310876 DataSet_03_258
CYP1A1 STAT3 siRNA Prostate LNCaP 1.52172 0.605704 0.108607354217637 0.15372732122717 DataSet_03_262
CYP1A1 STAT6 siRNA Umbilical_vein HUVEC 4.41197 2.14142 0.00919350382120413 0.507121113801904 DataSet_03_264
CYP1A1 TFE3 siRNA Kidney UOK257-2 0.484259 -1.04615 - - DataSet_03_275
CYP1A1 TP63 siRNA Skin Primary neonatal keratinocytes 0.387523 -1.36765 0.00815951687507856 0.0418806205095582 DataSet_03_281
CYP1A1 TP63 siRNA Foreskin Neonatal foreskin keratinocytes 1.73165 0.79215 0.104687449089724 0.739449081419525 DataSet_03_282
CYP1A1 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 1.71429 0.777608 0.297480851475341 0.742575819861349 DataSet_04_001
CYP1A1 CIZ1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.441177 -1.18057 0.123047571506533 0.206486128988989 DataSet_04_004
CYP1A1 ERN1 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.6 1.37851 0.190889394996244 0.746385818798742 DataSet_04_009
CYP1A1 RPS3 CRISPR Haematopoietic_and_lymphoid_tissue K562 5.5 2.45943 0.0244365723545737 0.395419358221978 DataSet_04_017
CYP1A1 SMAD2 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.125 1.08746 0.00130412284619598 0.0786343354168621 DataSet_04_018
CYP1A1 XRCC5 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.558824 -0.839535 0.252503430488901 0.489161000558771 DataSet_04_021
CYP1A1 ZNF574 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.583333 -0.777608 0.55193947093889 0.685508822906101 DataSet_04_023
CYP1A1 APTX CRISPR Liver HepG2 4.6 2.20163 0.0013821825711799 0.26153545007819 DataSet_04_025
CYP1A1 CIZ1 CRISPR Liver HepG2 0.626087 -0.675565 0.0768524828983162 0.294338984576097 DataSet_04_026
CYP1A1 E4F1 CRISPR Liver HepG2 1.60935 0.686477 0.0595389811409552 0.320632880685664 DataSet_04_028
CYP1A1 ERN1 CRISPR Liver HepG2 1.63949 0.71325 0.0020469782632913 0.0616247264343673 DataSet_04_029
CYP1A1 PAN2 CRISPR Liver HepG2 0.573333 -0.802554 0.0111949911200887 0.110571572995694 DataSet_04_033
CYP1A1 YBX1 CRISPR Liver HepG2 0.493455 -1.01901 0.137492043086825 0.972884761036538 DataSet_04_039
CYP1A1 ZNF574 CRISPR Liver HepG2 0.628148 -0.670823 0.0181479142394811 0.0884092974679495 DataSet_04_041
CYP1A1 ABT1 shRNA Liver HepG2 0.628763 -0.669413 0.0305218978215046 0.076939689143479 DataSet_04_052
CYP1A1 CCAR1 shRNA Liver HepG2 2.93578 1.55374 0.000130022740067145 0.00907135395817293 DataSet_04_054
CYP1A1 DDX1 shRNA Liver HepG2 1.52189 0.60586 0.240724964896015 0.482084100031554 DataSet_04_057
CYP1A1 PRPF6 shRNA Liver HepG2 0.608997 -0.715494 0.167803654837837 0.359833186411344 DataSet_04_056
CYP1A1 DDX17 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.25 1.16992 0.594963233353833 0.92290563574867 DataSet_04_047
CYP1A1 DDX20 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.92857 0.947533 0.447228495773295 0.785384430823389 DataSet_04_050
CYP1A1 NPM1 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.83333 0.874469 0.691547517832614 0.834253250963705 DataSet_04_046
CYP1A1 CITED2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.15385 1.10692 0.570145765073456 0.775941235705824 DataSet_02_38
CYP1A1 HMGA1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.06667 1.04731 0.450644347147809 0.780242232788874 DataSet_02_75
CYP1A1 HMGN3 CRISPRi Haematopoietic_and_lymphoid_tissue K562 3.30769 1.72583 0.263140019722647 0.725149508087263 DataSet_02_45
CYP1A1 LDB1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.53846 1.34395 0.179215082864685 0.324237160457351 DataSet_02_35
CYP1A1 NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 5.26923 2.39759 0.245764200662612 0.518267496783096 DataSet_02_32
CYP1A1 TBL1XR1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.307692 -1.70044 0.503146773589523 0.68422320651865 DataSet_02_43
CYP1A1 TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.461538 -1.11548 0.562356663535363 0.71407038626056 DataSet_02_33
CYP1A1 TLE2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.07692 1.05445 0.232368559893953 0.395196513370689 DataSet_02_53
CYP1A1 CNOT7 shRNA Haematopoietic_and_lymphoid_tissue K562 2 1 0.674705915471951 0.825735118667443 DataSet_04_061
CYP1A1 HDGF shRNA Haematopoietic_and_lymphoid_tissue K562 1.6 0.678072 0.731094828001451 0.82962595563117 DataSet_04_059
CYP1A1 PRPF6 shRNA Haematopoietic_and_lymphoid_tissue K562 0.47619 -1.07039 0.443036984479728 0.776078970129389 DataSet_04_065
CYP1A1 UBE2L3 shRNA Haematopoietic_and_lymphoid_tissue K562 0.238095 -2.07039 0.111970383144556 0.324798480520539 DataSet_04_062
CYP1A1 CNOT3 shRNA Lung A549 0.385618 -1.37476 3.348084e-02 0.8830540 DataSet_03_340
CYP1A1 EZH2 knockdown Uterus Ishikawa (ISK) cell 1.96564 0.975 - - DataSet_03_324
CYP1A1 SMARCA4 siRNA Colon HCT116 0.492812 -1.02089 5.002831e-03 0.1301617 DataSet_03_302
CYP1A1 ELF3 CRISPR Bile_duct HBDEC2 0.16769 -2.57613 1.177973e-06 1.264153e-04 DataSet_03_304
CYP1A1 ELF3 knockdown Bile_duct HBDEC2 0.648781 -0.624198 5.414485e-03 5.147689e-02 DataSet_03_305
CYP1A1 HDAC4 siRNA Liver human hepatocytes 0.583175 -0.778 2.178997e-05 2.194503e-03 DataSet_03_345
CYP1A1 SNAI2 shRNA Pancreas pancreatic cancer stem cells 0.305504 -1.71074 2.567577e-03 0.5311185 DataSet_03_306
CYP1A1 SNAI2 shRNA Pancreas KLM1 0.570651 -0.80932 7.989340e-02 0.37376512 DataSet_03_307
CYP1A1 ACTR5 siRNA Muscle RD 2.98629 1.57835 - - DataSet_03_343
CYP1A1 INO80 siRNA Muscle RD 3.41769 1.77302 - - DataSet_03_344
CYP1A1 ARID3B CRISPR Colon HCT15 0.397575 -1.3307 - - DataSet_03_335
CYP1A1 ZFX siRNA Prostate C4-2B 1.62402 0.699566 7.897830e-07 3.832798e-05 DataSet_03_348
CYP1A1 ZFX siRNA Mammary_gland MCF7 9.6786 3.2748 2.313400e-03 2.390513e-02 DataSet_03_349
CYP1A1 SKI CRISPR Blood HL60 0.392857 -1.34792 3.058576e-02 0.307754477 DataSet_03_351
CYP1A1 ETV5 knockdown Colon HT29 2.31788 1.21281 8.198257e-01 0.906079431 DataSet_03_353
CYP1A1 PARP1 siRNA Prostate LNCaP 1.57405 0.654483 6.494781e-01 0.836254629 DataSet_03_354
CYP1A1 TET1 CRISPR Mammary_gland Hs578T 1.67859 0.74725 1.877357e-01 3.650377e-01 DataSet_03_355
CYP1A1 CREBBP CRISPR Brain U5-NPC 2.57143 1.36257 0.3811134097 0.7490853 DataSet_03_356
CYP1A1 TP53 CRISPR Brain U5-NPC 2.28571 1.19265 7.666177e-02 2.127164e-01 DataSet_03_358
CYP1A1 ARID2 shRNA Haematopoietic_and_lymphoid_tissue MM.1S 0.353183 -1.50151 1.014289e-01 1.673081e-01 DataSet_03_362
CYP1A1 EP300 shRNA Mammary_gland MCF10AT 0.412844 -1.27633 4.803398e-03 0.048618007 DataSet_03_364
CYP1A1 TP53 knockout Stomach SNU1 8.78145 3.13446 0.1765891345 0.9301241 DataSet_03_365
CYP1A1 ZNF148 shRNA Mammary_gland MDA-MB-231 3.19711 1.67677 7.810605e-03 0.063659544 DataSet_03_366
CYP1A1 ABL1 shRNA Liver HuH7 1.83109 0.872705 3.964418e-06 0.0005205709 DataSet_03_367
CYP1A1 HNRNPU siRNA Colon RKO 3.39531 1.76354 - - DataSet_03_374
CYP1A1 GLI1 siRNA Skeletal_muscle RMS13 2.35192 1.23384 5.064101e-01 0.678862320 DataSet_03_375
CYP1A1 SMARCA2 shRNA Lung NCI-H1944 0.501025 -0.997045 2.446777e-03 1.522370e-01 DataSet_03_377
CYP1A1 EZH2 CRISPR Ovary SKOV3 11.6 3.53605 1.266781e-04 0.0063287039 DataSet_03_378
CYP1A1 DDX5 shRNA Stomach HGC-27 2.17606 1.12172 - - DataSet_03_379
CYP1A1 NFKB2 siRNA Bone_marrow U2OS 3.05263 1.61005 1.142442e-03 0.06724126 DataSet_03_381
CYP1A1 DNMT1 siRNA Skin Human melanoma cells 1.95833 0.969621 4.038783e-05 2.749656e-04 DataSet_03_382
CYP1A1 KAT6A CRISPR Haematopoietic_and_lymphoid_tissue MOLM-13 2.01821 1.01308 0.4947956565 0.8873980 DataSet_03_387
CYP1A1 TRIM8 siRNA Mammary_gland MCF7 2.90816 1.54011 8.440322e-04 0.0117118667 DataSet_03_388
CYP1A1 NFKBIA shRNA Bone_marrow U2OS 0.271834 -1.8792 4.581272e-01 0.87005461 DataSet_03_389
CYP1A1 YY1 knockdown Liver HepG2 6.18535 2.62885 1.965137e-07 3.700003e-06 DataSet_03_390
CYP1A1 KDM5A CRISPR Lung GLC16 2.33213 1.22165 2.578286e-02 0.077212811 DataSet_03_392
CYP1A1 ILF2 siRNA Stomach SGC-7901 2.05882 1.04182 0.0451237259 0.14686930 DataSet_03_393
CYP1A1 TLE4 CRISPR Lymph CAR T Cell 1.68785 0.755189 1.435426e-03 0.07828708 DataSet_03_398
CYP1A1 RELA CRISPR Brain T30 2.8169 1.49411 0.0940700950 0.8400824 DataSet_03_399
CYP1A1 HMGA1 shRNA Bile_duct HUCCT1 2.02254 1.01617 1.545383e-02 0.149233583 DataSet_03_400
CYP1A1 SUMO1 CRISPR Bone_marrow U2OS 0.474359 -1.07595 4.206938e-02 1.332392e-01 DataSet_03_401
CYP1A1 JARID2 siRNA Adipose_tissue human adipose tissue derived stem cells 9 3.16992 2.375104e-01 0.4412111 DataSet_03_403
CYP1A1 CDK7 shRNA Bone_marrow D458 8.5 3.08746 1.254342e-01 0.44353336 DataSet_03_404
CYP1A1 SATB2 CRISPR Colon Colon organoid 3.2311 1.69202 4.116116e-01 0.95735254 DataSet_03_406
CYP1A1 CHD1 shRNA Prostate LNCaP 1.86747 0.901085 9.305312e-04 5.679395e-02 DataSet_03_407
CYP1A1 MAP3K7 shRNA Prostate LNCaP 2.26506 1.17955 6.500753e-06 7.674511e-04 DataSet_03_408
CYP1A1 STRAP knockout Nerve SK-N-AS 2.20412 1.1402 - - DataSet_03_409
CYP1A1 SIRT1 siRNA Pancreas PANC1 0.328859 -1.60446 1.379881e-02 0.060325341 DataSet_03_410
CYP1A1 E2F2 siRNA Prostate LNCaP 3.14943 1.65509 3.140190e-05 1.749694e-03 DataSet_03_414
CYP1A1 RUNX2 shRNA Cord_blood Natural Killer Cell 0.346154 -1.53051 3.421972e-01 0.793390621 DataSet_03_416
CYP1A1 DNMT3B shRNA Embryo 2102Ep 0.662652 -0.593676 7.953719e-06 1.087910e-03 DataSet_03_417
CYP1A1 FOXK2 shRNA Ovary OVCAR-5 4.09722 2.03465 4.296718e-03 0.08266460 DataSet_03_419
CYP1A1 BRD4 CRISPR Lymph CD8+ T cells 1.50173 0.586626 - - DataSet_03_420
CYP1A1 MAEL CRISPR Liver Alexander cells 0.184795 -2.436 - - DataSet_03_423
CYP1A1 FOXP3 CRISPR Peripheral_blood Naive Treg 2.78243 1.47634 4.983679e-02 0.313242566 DataSet_03_427
CYP1A1 LHX2 shRNA Bone_marrow ES-derived RPE cells 3.5 1.80735 4.992100e-02 1.000000e+00 DataSet_03_428
CYP1A1 STAT3 siRNA Peripheral_blood Monocyte-derived M-CSF macrophages 0.26087 -1.9386 0.3903093119 1 DataSet_03_430
CYP1A1 USP7 shRNA Skin xenograft cells 0.430543 -1.21577 0.26163265 0.4348960 DataSet_03_431
CYP1A1 PLAG1 shRNA Cord_blood Lin-CD34+ HSPCs 0.542683 -0.881819 - - DataSet_03_432
CYP1A1 POU2AF1 CRISPR Haematopoietic_and_lymphoid_tissue OCI-Ly7 0.41202 -1.27921 2.637703e-01 0.574894029 DataSet_03_434
CYP1A1 POU2AF1 CRISPR Lymph SUDHL4 29.9151 4.9028 2.695890e-03 0.019316376 DataSet_03_435
CYP1A1 EP300 knockout Pancreas HPAF-II orthotopic cells 5.23125 2.38716 1.546501e-02 5.830201e-02 DataSet_03_436
CYP1A1 CIC knockout Brain Immortalized Astrocyte Cells 1.5655 0.646619 2.351280e-01 6.776163e-01 DataSet_03_438
CYP1A1 SETDB1 shRNA Colon HCT116 3.84992 1.94483 - - DataSet_03_440
CYP1A1 PHF14 siRNA Mammary_gland MDA-MB-231 0.398357 -1.32787 0.0125466816 0.2851977 DataSet_03_443
CYP1A1 FOSL1 siRNA Prostate MSKPCa3 2.39655 1.26096 0.0422386597 0.4361780 DataSet_03_445
CYP1A1 CBX2 siRNA Mammary_gland MCF7 7.59577 2.92519 2.887320e-04 0.0025360293 DataSet_03_451
CYP1A1 OGT siRNA Embryo BeWo cells 0.656061 -0.608099 1.602980e-02 0.41762810 DataSet_03_453
CYP1A1 SREBF2 siRNA Umbilical_vein HUVEC 2.7856 1.47799 9.740934e-02 4.851113e-01 DataSet_03_457
CYP1A1 IRF2 shRNA Cord_Blood CD34+ cells 0.113445 -3.13993 - - DataSet_03_460
CYP1A1 TXNIP shRNA Cord_Blood CD34+ cells 0.113445 -3.13993 - - DataSet_03_461
CYP1A1 PARP1 knockout Embryo_kidney HEK293a 2.70388 1.43503 1.916645e-06 2.428910e-05 DataSet_03_464
CYP1A1 STAT3 shRNA Liver HepG2 2.30582 1.20528 2.427650e-03 0.0671167305 DataSet_03_465
CYP1A1 SMARCA1 Cas13 Embryo_kidney HEK293T 0.532468 -0.909235 - - DataSet_03_466
CYP1A1 SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 2.15584 1.10825 - - DataSet_03_467
CYP1A1 SMARCA1 shRNA Embryo_kidney HEK293T 0.532468 -0.909235 - - DataSet_03_468
CYP1A1 EZH2 siRNA Prostate LNCaP 4.06729 2.02407 - - DataSet_03_472
CYP1A1 CREBBP CRISPR Lymph U2932 1.6 0.678072 3.510112e-01 1.0000000 DataSet_03_474
CYP1A1 CHCHD3 CRISPR Haematopoietic_and_lymphoid_tissue K562 4 2 0.4707338 0.9402719 DataSet_04_071
CYP1A1 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 1.71429 0.777608 0.3640355 0.780522 DataSet_04_072
CYP1A1 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 4.25 2.08746 0.2211994 0.369794284 DataSet_04_074
Regulation Region
 
T(co)Fs that significantly regulate SOX2 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of CYP1A1
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines