Gene Overview
Target Gene: IFI6
NCBI Official Symbol: IFI6
Entrez ID: 2537
Ensembl ID: ENSG00000126709
Gene Full Name: interferon alpha inducible protein 6
Strand: -
Gene Locus: 1p35.3
External Links:

IFI6 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate IFI6   
T(co)Fs that Repress IFI6
The Intensity of the Gene Regulated by T(co)Fs:
IFI6-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
IFI6 HNF1B shRNA Ovary RMG2 0.65038 -0.62064 0.24272 0.32927 DataSet_01_103
IFI6 SPDEF shRNA Mammary_gland MCF7 0.35396 -1.49833 0.34796 0.99999 DataSet_01_107
IFI6 ARID1A shRNA Ovary OSE4 0.45056 -1.1502 - - DataSet_01_108
IFI6 HSF1 siRNA Upper_aerodigestive_tract HSC3 1.58632 0.66568 0.00184 0.07413 DataSet_01_112
IFI6 TCF3 shRNA Mammary_gland MDA-MB468 0.5852 -0.773 1.56138e-05 0.00069 DataSet_01_116
IFI6 ID1 siRNA Lung A549 4.51441 2.17454 0.01692 0.16457 DataSet_01_117
IFI6 GATA3 siRNA Mammary_gland MCF7 0.40527 -1.30306 1.11872e-05 0.00065 DataSet_01_120
IFI6 ZIC2 siRNA Pancreas PANC1 2.53937 1.34447 - - DataSet_01_121
IFI6 FOXM1 siRNA Central_nervous_system U87 4.79394 2.26121 - - DataSet_01_122
IFI6 NFYA shRNA Cervix HeLaS3 1.74623 0.80424 5.94211e-05 0.0033 DataSet_01_131
IFI6 ID1 shRNA Neuroepithelium GSC8 0.05964 -4.06767 5.47892e-17 3.74362e-14 DataSet_01_134
IFI6 SPDEF shRNA Mammary_gland MCF7 5.44729 2.44554 1.00408e-06 0.00251 DataSet_01_135
IFI6 ZFX shRNA Haematopoietic_and_lymphoid_tissue NOMO-1 1.76986 0.82363 0.04523 0.99999 DataSet_01_144
IFI6 TFAP2C shRNA Mammary_gland MCF7 2.72017 1.4437 1.22148e-11 4.30511e-10 DataSet_01_150
IFI6 TAL1 shRNA Umbilical_cord_blood ECFCs 1.81782 0.86221 0.0977 0.61765 DataSet_01_152
IFI6 ELK1 siRNA Peripheral_blood CD4+ T cells 62668.1 15.9354 5.7274e-15 1.11816e-10 DataSet_01_162
IFI6 JUN siRNA Peripheral_blood CD4+ T cells 34779.1 15.0859 9.66374e-05 0.00365 DataSet_01_164
IFI6 MAF siRNA Peripheral_blood CD4+ T cells 52142.4 15.6702 5.30179e-15 2.58767e-11 DataSet_01_165
IFI6 NFATC3 siRNA Peripheral_blood CD4+ T cells 30479.3 14.8955 0.00018 0.0109 DataSet_01_166
IFI6 HOXB7 siRNA Pancreas MIA PaCa-2 1.52104 0.60506 0.03705 0.6094 DataSet_01_169
IFI6 HSF1 shRNA Liver KYN2 1.65644 0.72808 - - DataSet_01_178
IFI6 NR5A2 siRNA Mammary_gland MCF7 0.45753 -1.12808 0.04689 0.24318 DataSet_01_182
IFI6 TP63 shRNA Bladder UC14 3.07887 1.6224 4.59767e-07 4.00875e-05 DataSet_01_183
IFI6 TCF4 siRNA Autonomic_ganglia SH-SY5Y 2.24322 1.16557 0.03969 0.15957 DataSet_01_185
IFI6 GABPA shRNA Prostate C4-2B 1174.4 10.1977 0.23564 0.43934 DataSet_01_190
IFI6 GABPA shRNA Prostate LNCaP 778.155 9.60391 0.45932 0.7048 DataSet_01_191
IFI6 TP63 siRNA Immortalized_keratinocyte HaCaT RG 2.72619 1.44689 - - DataSet_01_196
IFI6 TP63 siRNA Head_and_neck SCC-1 1.68999 0.75702 - - DataSet_01_198
IFI6 TP63 siRNA Head_and_neck SCC-6 2.80039 1.48563 - - DataSet_01_202
IFI6 XBP1 shRNA Mammary_gland MDA-MB-231 1.56552 0.64664 0.00075 0.01478 DataSet_01_204
IFI6 MITF shRNA Skin COLO829 2.05773 1.04105 0.00026 0.00992 DataSet_01_207
IFI6 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 0.53873 -0.89238 - - DataSet_01_210
IFI6 EGR3 shRNA Prostate M12 0.27242 -1.8761 0.0338 0.19367 DataSet_01_212
IFI6 BCLAF1 shRNA Colon RKO 0.6584 -0.60297 - - DataSet_01_214
IFI6 LIN28A siRNA Embryo H9 1.91042 0.93389 0.00171 0.01703 DataSet_01_215
IFI6 ATM shRNA Mammary_gland MCF10A 1.69995 0.76549 0.26079 0.47018 DataSet_01_219
IFI6 KLF3 shRNA Haematopoietic_and_lymphoid_tissue K562 1.53036 0.61387 1.6716e-07 1.27741e-05 DataSet_01_221
IFI6 FOXM1 siRNA Mammary_gland MCF7 273.636 8.09612 3.86015e-07 0.00226 DataSet_01_223
IFI6 SNAI2 shRNA Skin Primary human keratinocytes 0.42996 -1.21772 0.00038 0.01095 DataSet_01_225
IFI6 KLF2 shRNA Bone_marrow RPMI8226 3.37363 1.7543 0.00294 0.415 DataSet_01_226
IFI6 MYC siRNA White_adipose_tissue Adipose stem cells 1.77335 0.82647 0.03492 0.17457 DataSet_01_231
IFI6 STAT5 shRNA Haematopoietic_and_lymphoid_tissue K562 8.09535 3.01709 2.00898e-07 7.87825e-05 DataSet_01_239
IFI6 TWIST1 shRNA Stomach CAF14 2.30223 1.20304 0.08686 0.99996 DataSet_01_252
IFI6 TWIST1 shRNA Stomach CAF 1.56453 0.64573 0.38723 0.78866 DataSet_01_254
IFI6 YBX1 shRNA Mammary_gland MDA 1.74283 0.80143 0.00182 0.01429 DataSet_01_257
IFI6 HES1 shRNA Haematopoietic_and_lymphoid_tissue_Blood CUTLL1 2.03905 1.0279 5.37723e-07 1e-04 DataSet_01_266
IFI6 FOXO1 siRNA Umbilical_vein HUVEC 1.56518 0.64633 0.00401 0.03936 DataSet_01_270
IFI6 SALL4 shRNA Lung H661 0.41666 -1.26306 0.01062 0.12623 DataSet_01_277
IFI6 NFYA shRNA Lung H322 0.61471 -0.70203 0.0158 0.05885 DataSet_01_288
IFI6 POSTN shRNA Brain GSC272 0.18846 -2.40766 0.00791 0.47578 DataSet_01_293
IFI6 TFAP4 siRNA Brain BE(2)-C 0.1459 -2.77694 0.26639 0.51625 DataSet_01_295
IFI6 SOX17 siRNA Umbilical_vein HUVEC 0.36209 -1.46558 0.26831 0.99998 DataSet_01_300
IFI6 PTEN shRNA Skin A431 1.68215 0.7503 0.01083 0.09875 DataSet_01_301
IFI6 NR2E1 shRNA Neuroepithelium PBT003 1.71838 0.78105 0.36831 0.74503 DataSet_01_306
IFI6 ARNT shRNA Embryo WA09/H9 1.56754 0.6485 0.1515 0.99363 DataSet_01_307
IFI6 BRD4 siRNA Ovary Ovcar8 2.09937 1.06996 0.00466 0.02259 DataSet_01_311
IFI6 OVOL2 siRNA Corneal_epithelial Corneal epithelial cells 0.37518 -1.41434 0.01551 0.26258 DataSet_01_313
IFI6 RUNX1 shRNA Embryo H9 1.53852 0.62155 0.00088 0.02531 DataSet_01_314
IFI6 ERG siRNA Cervix HeLa 6.22453 2.63797 4.85998e-10 7.77517e-09 DataSet_01_316
IFI6 ELK3 shRNA Mammary_gland MDA-MB-231 1.87128 0.90403 2e-04 0.00098 DataSet_01_318
IFI6 MYC siRNA Colon HCT116 2.34506 1.22963 5.54093e-05 0.00026 DataSet_01_324
IFI6 TP63 shRNA Immortalized_keratinocyte HaCaT 3.64787 1.86705 1.51208e-10 1.6724e-07 DataSet_01_325
IFI6 TP63 shRNA Immortalized_keratinocyte HaCaT 3.64787 1.86705 1.51208e-10 1.6724e-07 DataSet_01_328
IFI6 HOXC6 siRNA Prostate LNCaP 0.64132 -0.64088 0.29421 0.99927 DataSet_01_333
IFI6 NFE2L2 siRNA Lung A549 1.57178 0.6524 4.28372e-06 0.00021 DataSet_01_335
IFI6 REST siRNA Skin NHEK 1.86377 0.89822 0.00073 0.0299 DataSet_01_337
IFI6 TCF7L1 shRNA Colon HCT116 0.60592 -0.7228 0.00017 0.0077 DataSet_01_346
IFI6 SOX2 shRNA Neuroepithelium HF2303 0.24505 -2.02885 0.00314 1 DataSet_01_349
IFI6 ETV4 shRNA Prostate PC3 1.94312 0.95838 - - DataSet_01_356
IFI6 PAX3 shRNA Soft_tissue Rh30 1.92007 0.94116 - - DataSet_01_359
IFI6 GTF2B siRNA Cervix HeLa 0.58884 -0.76404 - - DataSet_01_362
IFI6 RBM17 shRNA Liver HepG2 0.48798 -1.03512 0.00729 0.26816 DataSet_02_100
IFI6 FIP1L1 shRNA Liver HepG2 2.01541 1.01107 0.01311 0.04767 DataSet_02_103
IFI6 U2AF2 shRNA Liver HepG2 0.48207 -1.05269 0.04872 0.14238 DataSet_02_105
IFI6 TAF15 shRNA Liver HepG2 0.64836 -0.62513 0.06609 0.11032 DataSet_02_106
IFI6 ZNF622 shRNA Liver HepG2 1.5847 0.66421 0.00534 0.01905 DataSet_02_108
IFI6 GTF2F1 shRNA Liver HepG2 1.52711 0.6108 0.06304 0.33546 DataSet_02_110
IFI6 TARDBP shRNA Liver HepG2 3.51934 1.8153 0.00244 0.02043 DataSet_02_116
IFI6 PTBP1 shRNA Liver HepG2 3.7736 1.91594 0.00575 0.01605 DataSet_02_120
IFI6 EWSR1 shRNA Liver HepG2 2.04038 1.02884 0.00207 0.04273 DataSet_02_122
IFI6 FUS shRNA Liver HepG2 2.11927 1.08356 0.00192 0.05473 DataSet_02_124
IFI6 HNRNPLL shRNA Liver HepG2 0.63674 -0.65122 0.02898 0.06551 DataSet_02_125
IFI6 SNRNP70 shRNA Liver HepG2 1.75691 0.81304 0.01099 0.05428 DataSet_02_126
IFI6 SRSF3 shRNA Liver HepG2 1.73895 0.79822 0.06082 0.17439 DataSet_02_127
IFI6 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.59091 -0.75899 0.00204 0.02902 DataSet_02_131
IFI6 AGO2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.52778 -0.922 0.10094 0.24624 DataSet_02_132
IFI6 SRSF7 shRNA Haematopoietic_and_lymphoid_tissue K562 0.65613 -0.60795 0.00947 0.22541 DataSet_02_133
IFI6 RBFOX2 shRNA Haematopoietic_and_lymphoid_tissue K562 1.69096 0.75784 0.0253 0.45829 DataSet_02_139
IFI6 TAF15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.62199 -0.68503 0.63168 0.79668 DataSet_02_140
IFI6 BCLAF1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.50336 1.32386 0.00077 0.08476 DataSet_02_142
IFI6 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 1.70048 0.76594 0.0562 0.10743 DataSet_02_143
IFI6 CCAR2 shRNA Haematopoietic_and_lymphoid_tissue K562 1.75362 0.81034 0.00301 0.38027 DataSet_02_146
IFI6 FIP1L1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.81967 1.49553 0.00421 0.08379 DataSet_02_147
IFI6 ILF3 shRNA Haematopoietic_and_lymphoid_tissue K562 2.02624 1.0188 0.00776 0.2373 DataSet_02_148
IFI6 NONO shRNA Haematopoietic_and_lymphoid_tissue K562 3.03086 1.59973 0.00102 0.19424 DataSet_02_149
IFI6 SAFB2 shRNA Haematopoietic_and_lymphoid_tissue K562 2.91667 1.54432 0.00726 0.41496 DataSet_02_150
IFI6 RBM39 shRNA Haematopoietic_and_lymphoid_tissue K562 1.51095 0.59545 0.08506 0.28669 DataSet_02_151
IFI6 ILF2 shRNA Haematopoietic_and_lymphoid_tissue K562 1.9749 0.98178 0.02384 0.2779 DataSet_02_152
IFI6 GTF2F1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.52201 0.60598 0.05046 0.87116 DataSet_02_157
IFI6 HNRNPL shRNA Haematopoietic_and_lymphoid_tissue K562 1.56684 0.64786 0.09228 0.24908 DataSet_02_160
IFI6 U2AF1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.38488 -1.37752 0.01354 0.14234 DataSet_02_165
IFI6 U2AF2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.54124 -0.88567 0.04874 0.13401 DataSet_02_170
IFI6 NFE2L2 siRNA Haematopoietic_and_lymphoid_tissue K562 1.52954 0.6131 0.18725 1 DataSet_02_174
IFI6 RAD21 siRNA Haematopoietic_and_lymphoid_tissue K562 1.59239 0.67119 0.17563 1 DataSet_02_190
IFI6 TCP1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.66272 -0.59352 0.18469 1 DataSet_02_194
IFI6 UBTF siRNA Haematopoietic_and_lymphoid_tissue K562 1.61341 0.69012 0.31625 1 DataSet_02_198
IFI6 ZNF384 siRNA Haematopoietic_and_lymphoid_tissue K562 1.62785 0.70297 0.0763 1 DataSet_02_203
IFI6 ABL1 siRNA Mammary_gland MCF7 0.479754 -1.05963 0.0543516512406849 0.976385569407162 DataSet_03_001
IFI6 AKT1 siRNA Mammary_gland MCF7 0.659733 -0.600045 0.229187273052284 0.937512920166337 DataSet_03_002
IFI6 AR siRNA Prostate abl cells 1.9461 0.960583 0.119802406697487 0.999852161656754 DataSet_03_004
IFI6 AR siRNA Prostate LNCaP 1.79884 0.847066 0.31669064993521 1 DataSet_03_005
IFI6 ARID1A siRNA Mammary_gland MDA-MB-157 1.60072 0.678722 - - DataSet_03_014
IFI6 ATOH8 siRNA Umbilical_vein HUVEC 1.99878 0.999123 0.0366386870642192 0.671527781959894 DataSet_03_019
IFI6 ATR siRNA Mammary_gland MCF7 0.582219 -0.780367 0.131312345128581 0.999819450785634 DataSet_03_020
IFI6 BRCA2 siRNA Mammary_gland MCF7 0.566969 -0.818659 0.116396816443384 0.999441861952364 DataSet_03_029
IFI6 CCNA2 siRNA Mammary_gland MCF7 0.351177 -1.50973 0.0138916984063358 0.872422373040044 DataSet_03_034
IFI6 CDK2 siRNA Mammary_gland MCF7 0.472609 -1.08128 0.0507804582074647 0.99987175116756 DataSet_03_044
IFI6 CEBPA siRNA Mammary_gland MCF7 1.51402 0.598383 0.230338800183963 0.999962793175751 DataSet_03_047
IFI6 CEBPB siRNA Mammary_gland MCF7 0.45994 -1.12048 0.0449189765718039 0.993756826434039 DataSet_03_048
IFI6 CEBPD siRNA Mammary_gland MCF7 0.350476 -1.51261 0.0137765402300721 0.999848455332859 DataSet_03_050
IFI6 CHEK1 siRNA Mammary_gland MCF7 0.491734 -1.02405 0.0607942368697695 0.999587656258211 DataSet_03_053
IFI6 CREBBP siRNA Mammary_gland MCF7 0.42489 -1.23484 0.0315287844757799 0.963067261754673 DataSet_03_055
IFI6 CTNNB1 siRNA Mammary_gland MCF7 1.51767 0.601859 0.227937437882209 0.999436862066063 DataSet_03_058
IFI6 E2F1 siRNA Mammary_gland MCF7 1.53141 0.614859 0.219151959636008 0.999927373439084 DataSet_03_061
IFI6 E2F5 siRNA Mammary_gland MCF7 1.6876 0.754975 0.142200733785308 0.999540347732068 DataSet_03_062
IFI6 E2F7 siRNA Upper_aerodigestive_tract SCC25 0.354432 -1.49642 1.86127609977208e-09 1.17030665351451e-06 DataSet_03_063
IFI6 ERBB2 siRNA Mammary_gland MCF7 0.649301 -0.623041 0.213778045685681 0.998282799776643 DataSet_03_066
IFI6 ERF siRNA Mammary_gland MCF7 0.541216 -0.885722 0.0941606653360809 0.999855523449227 DataSet_03_067
IFI6 FOS siRNA Mammary_gland MCF7 0.536185 -0.899198 0.0902277805516751 0.999966427400474 DataSet_03_079
IFI6 FOXA1 siRNA Mammary_gland MCF7 2.73269 1.45032 5.39382940805634e-07 4.67833793707767e-05 DataSet_03_080
IFI6 FOXA1 siRNA Mammary_gland MCF7 0.535586 -0.900809 8.3908760652561e-05 0.000982874385951224 DataSet_03_081
IFI6 FOXA1 siRNA Mammary_gland MCF7 0.535586 -0.900809 8.3908760652561e-05 0.000982874385951224 DataSet_03_082
IFI6 FOXC1 siRNA Mammary_gland MCF7 0.6139 -0.703925 0.16673543421407 0.999669928105298 DataSet_03_084
IFI6 FOXJ2 siRNA Mammary_gland MCF7 0.632396 -0.6611 0.190309636790886 0.999965704179325 DataSet_03_088
IFI6 FOXK1 siRNA Cervix HeLa 1.50741 0.592067 3.00502031983727e-08 0.000100054297992068 DataSet_03_089
IFI6 FOXM1 siRNA Aorta Vascular smooth muscle cells 1.78757 0.838001 - - DataSet_03_090
IFI6 FOXM1 siRNA Mammary_gland BT-20 cells 0.555556 -0.847997 0.0928804765044918 0.505121775366111 DataSet_03_091
IFI6 FOXO1 shRNA Haematopoietic_and_lymphoid_tissue Namalwa 2.42933 1.28056 4.73528207842868e-05 0.0188050517418353 DataSet_03_095
IFI6 FOXO1 siRNA Skin primary human dermal lymphatic endothelial cells 1.79799 0.846386 - - DataSet_03_096
IFI6 FOXP1 siRNA Mammary_gland MCF7 0.532606 -0.908859 0.0875093835144007 0.999975993110711 DataSet_03_099
IFI6 GATA3 siRNA Mammary_gland MCF7 0.47461 -1.07518 0.0517608538594012 0.999831535534034 DataSet_03_102
IFI6 GATA3 siRNA Mammary_gland MCF7 0.62191 -0.685221 0.00278086895189473 0.0539740996527419 DataSet_03_103
IFI6 GFP siRNA Upper_aerodigestive_tract SCC25 0.330119 -1.59894 9.61616801609361e-08 4.92933871665928e-05 DataSet_03_112
IFI6 HES6 siRNA Brain LN405 0.602073 -0.73199 0.019962708061161 0.959972868676594 DataSet_03_117
IFI6 HNF4a siRNA Liver HepG2 0.545847 -0.873432 0.141648767254084 0.763035834549052 DataSet_03_126
IFI6 ID1 siRNA Mammary_gland MCF7 0.4587 -1.12438 0.0443762734844992 0.999926480273844 DataSet_03_133
IFI6 IRF4 siRNA Skin Cutaneous T cell lymphoma HuT-102 cells 4.98591 2.31786 0.0405256795044977 0.78777701047567 DataSet_03_134
IFI6 JUN siRNA Fibroblasts WI38 0.530607 -0.914286 0.0916577364865559 0.232971827513715 DataSet_03_140
IFI6 JUN siRNA Fibroblasts WI38 0.530607 -0.914286 0.0916336455861842 0.232717232911321 DataSet_03_141
IFI6 JUN siRNA Mammary_gland MCF7 0.319353 -1.64678 0.0233080916428042 0.999857657786768 DataSet_03_142
IFI6 JUND siRNA Mammary_gland MCF7 0.396589 -1.33428 0.00941406933215276 0.999848956486105 DataSet_03_145
IFI6 KDM3A siRNA Mammary_gland MCF7 1.92604 0.94564 3.99003011155405e-06 0.000723499032094404 DataSet_03_146
IFI6 Klf4 siRNA Skin Primary neonatal keratinocytes 2.46361 1.30078 0.00012183276172638 0.00245422181877651 DataSet_03_147
IFI6 KLF5 siRNA Colon SW480 0.627427 -0.672481 0.000468322995507824 0.048936036181397 DataSet_03_148
IFI6 KLF5 siRNA Stomach KatoIII 1.59404 0.672687 0.00214963985896039 0.138131902509755 DataSet_03_150
IFI6 MAPK1 siRNA Mammary_gland MCF7 0.509336 -0.97331 0.0704996595479483 0.999829384224364 DataSet_03_156
IFI6 MAPK14 siRNA Mammary_gland MCF7 0.507984 -0.977144 0.0713594850612227 0.999824418484635 DataSet_03_157
IFI6 MAX siRNA Mammary_gland MCF7 0.383312 -1.38341 0.0201218103044755 0.999907009675999 DataSet_03_158
IFI6 MCM2 siRNA Mammary_gland MCF7 0.393167 -1.34679 0.0224488440830993 0.999925560383539 DataSet_03_161
IFI6 MITF siRNA Skin MZ7 1.7332 0.793437 1.98588070425647e-06 2.83648189186801e-05 DataSet_03_165
IFI6 MYB siRNA Cord_Blood CD34+ progenitor cells 1.78417 0.835253 - - DataSet_03_170
IFI6 MYBL2 siRNA Mammary_gland MCF7 0.488822 -1.03262 0.0591743951570696 0.999907476570542 DataSet_03_176
IFI6 MYC siRNA Colon HT29 4.27566 2.09615 - - DataSet_03_177
IFI6 MYC siRNA Central_nervous_system DAOY M2.1 1.73782 0.79728 9.96101488828072e-06 4.95647466465347e-05 DataSet_03_178
IFI6 MYC siRNA Mammary_gland MCF7 0.649042 -0.623615 0.213405140684304 0.999887767096734 DataSet_03_182
IFI6 NCOR2 siRNA Mammary_gland MCF7 0.339906 -1.55679 0.0121354835987793 0.999834929103349 DataSet_03_193
IFI6 NMI siRNA Mammary_gland MCF7 0.65727 -0.605442 0.225484600159475 0.783569713919107 DataSet_03_199
IFI6 NR4A3 siRNA Pancreas 1.1B4 2.00163 1.00118 5.22525345429441e-07 2.02140580143516e-05 DataSet_03_203
IFI6 PBX1 siRNA Mammary_gland MCF7 2.04222 1.03014 0.00027980124538029 0.509562246981515 DataSet_03_207
IFI6 PBX1 siRNA Mammary_gland LTED 1.95028 0.963684 0.000165894287282522 0.644454904907285 DataSet_03_208
IFI6 POLR2A siRNA Mammary_gland MCF7 0.622711 -0.683364 0.241114876105688 0.999513313282531 DataSet_03_213
IFI6 PRRX1 siRNA Skin Fibroblast 1.71622 0.779233 0.00633755513498923 0.218197608200054 DataSet_03_216
IFI6 PRRX1 CRISPR Neuroblastoma 691-MES 0.381541 -1.39009 0.222499099001894 0.894427234823585 DataSet_03_217
IFI6 RARA siRNA Mammary_gland MCF7 0.445901 -1.1652 2.32365900825833e-06 0.000554773221685779 DataSet_03_218
IFI6 RELA siRNA Fibroblasts WI38 0.166168 -2.58929 0.000146664730692533 0.00389202440118298 DataSet_03_222
IFI6 RELA siRNA Fibroblasts WI38 0.13973 -2.83929 2.25969090043912e-06 9.5309459001655e-05 DataSet_03_223
IFI6 RELA siRNA Mammary_gland MCF7 0.469656 -1.09032 0.0493616056687575 0.999993711976373 DataSet_03_224
IFI6 RELB siRNA Pancreas MIA PaCa-2 2.79935 1.48509 1.73838687155776e-05 0.00700807444307563 DataSet_03_225
IFI6 SMAD7 siRNA Mammary_gland MCF7 0.525543 -0.928118 0.0823317616511665 0.99858912864726 DataSet_03_234
IFI6 SOX11 siRNA Lung_fibroblast NHLF 1.70777 0.772113 0.0126312969692192 0.308493468732866 DataSet_03_237
IFI6 SOX11 siRNA Lung_fibroblast NHLF 1.86193 0.896796 0.119663692657352 0.476611464394485 DataSet_03_238
IFI6 SOX2 siRNA Lung H520 0.655418 -0.609514 - - DataSet_03_240
IFI6 SOX2 CRISPR Seminoma-like TCam-2 4.25298 2.08847 0.0583047909364241 0.999580851453413 DataSet_03_244
IFI6 SP1 siRNA Cervix HeLa 1.83056 0.872287 4.2273126959774e-05 0.00107570454090941 DataSet_03_249
IFI6 SP1 siRNA Mammary_gland MDA-MB-231 3.787 1.92106 0.00128857332599271 0.413972819854456 DataSet_03_250
IFI6 SP1 siRNA Ovary OVSAYO 2.24787 1.16856 0.002169875700363 0.0820174146518692 DataSet_03_251
IFI6 STAT1 siRNA Mammary_gland MCF7 0.499131 -1.00251 0.0650693464081656 0.999890411872485 DataSet_03_256
IFI6 STAT3 CRISPR Embryo hESC 3.18141 1.66966 0.0247986473234613 0.0905910619436736 DataSet_03_258
IFI6 TCEA1 siRNA Mammary_gland MCF7 2.35287 1.23442 0.0315689366846456 0.999762252994287 DataSet_03_266
IFI6 TET2 siRNA Embryo NCCIT 0.611488 -0.709605 7.32273946893576e-05 0.00209669642263496 DataSet_03_270
IFI6 TFAP2C siRNA Mammary_gland MCF7 20.3433 4.34648 0.000241894501519774 0.163694544700335 DataSet_03_274
IFI6 TP63 siRNA Skin Primary neonatal keratinocytes 2.49564 1.31941 0.000438329369266954 0.00653051555725617 DataSet_03_281
IFI6 WT1 siRNA Mammary_gland MCF7 0.385481 -1.37527 0.0206157837911678 0.999957852801679 DataSet_03_285
IFI6 CIZ1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.574282 -0.800168 0.0481347395688021 0.105559452959329 DataSet_04_004
IFI6 EIF2AK2 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.29208 1.19666 0.00790041972348256 0.452673378973461 DataSet_04_008
IFI6 FUBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 4.48619 2.16549 0.000137958799890533 0.0536237768466547 DataSet_04_010
IFI6 MARK2 shRNA Haematopoietic_and_lymphoid_tissue K562 1.8939 0.92136 0.00306203305811984 0.0163543667656758 DataSet_04_012
IFI6 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 2.14584 1.10154 0.429992910037272 0.573808851034051 DataSet_04_014
IFI6 PAN2 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.55801 0.639705 0.00883889997014766 0.737667315848746 DataSet_04_016
IFI6 SMAD2 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.632505 -0.660851 0.0261800258281422 0.113830226282151 DataSet_04_018
IFI6 SMAD5 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.653266 -0.614257 0.0282382377943305 0.395800493182546 DataSet_04_020
IFI6 ZNF574 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.453704 -1.14018 0.0102247670697818 0.116203103779809 DataSet_04_023
IFI6 APTX CRISPR Liver HepG2 0.556784 -0.84481 0.0172876820460866 0.42719489609408 DataSet_04_025
IFI6 CIZ1 CRISPR Liver HepG2 1.52014 0.604202 0.186126928623099 0.425267327195804 DataSet_04_026
IFI6 PAN2 CRISPR Liver HepG2 1.5274 0.611079 0.0143911579494526 0.119802602358889 DataSet_04_033
IFI6 SMAD2 CRISPR Liver HepG2 1.98682 0.990459 0.000743264564280131 0.279166152697324 DataSet_04_034
IFI6 SMAD4 CRISPR Liver HepG2 1.63388 0.708302 0.00235610297550922 0.0686419036144452 DataSet_04_035
IFI6 YBX1 CRISPR Liver HepG2 0.452902 -1.14273 0.617193347903296 0.972884761036538 DataSet_04_039
IFI6 CHCHD3 CRISPR Liver HepG2 1.61939 0.695454 0.00125458524445999 0.462359872902174 DataSet_04_067
IFI6 PAN2 CRISPR Liver HepG2 1.63388 0.708302 0.000509416983008322 0.021431285935823 DataSet_04_066
IFI6 ABT1 shRNA Liver HepG2 2.40565 1.26643 0.000375375008159873 0.00485562129401031 DataSet_04_052
IFI6 CCAR1 shRNA Liver HepG2 11.8805 3.57053 1.11328904612432e-05 0.0058084645884747 DataSet_04_054
IFI6 PRPF6 shRNA Liver HepG2 1.52214 0.6061 0.00832719386251959 0.0712973567074173 DataSet_04_056
IFI6 UBE2L3 shRNA Liver HepG2 1.59769 0.675988 0.0100897644393158 0.040295143661085 DataSet_04_055
IFI6 ACTN4 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.593542 -0.752577 0.00314397115838403 0.0534226938050582 DataSet_04_048
IFI6 RIOK2 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.515595 -0.955691 0.00294575940958969 0.518573533515985 DataSet_04_076
IFI6 SNW1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.623946 -0.680507 0.0428830591506451 0.111935003647059 DataSet_04_049
IFI6 DPF2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.540091 -0.888726 0.000610646369408565 0.00878389418039152 DataSet_02_14
IFI6 SNW1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.539056 -0.891493 0.014286010423271 0.396811658374965 DataSet_02_49
IFI6 ABT1 shRNA Haematopoietic_and_lymphoid_tissue K562 4.8895 2.28969 1.76483081809576e-05 0.0103600436529567 DataSet_04_060
IFI6 CCAR1 shRNA Haematopoietic_and_lymphoid_tissue K562 3.62573 1.85827 0.000212545930773334 0.0366438790055592 DataSet_04_064
IFI6 CNOT7 shRNA Haematopoietic_and_lymphoid_tissue K562 4.08368 2.02987 0.00131172775393187 0.0446588303490248 DataSet_04_061
IFI6 HDGF shRNA Haematopoietic_and_lymphoid_tissue K562 0.580902 -0.783634 0.0197306967276009 0.0492411146032868 DataSet_04_059
IFI6 PRPF6 shRNA Haematopoietic_and_lymphoid_tissue K562 2.00629 1.00453 0.036368500745992 0.324593604639847 DataSet_04_065
IFI6 EZH2 shRNA Colon SW480 3.07344 1.61986 - - DataSet_03_298
IFI6 DNMT1 siRNA Lung_fibroblast IMR-90 2.11011 1.07732 4.642674e-02 0.9999458 DataSet_03_317
IFI6 TET1 siRNA Lung A549 0.645006 -0.632615 - - DataSet_03_318
IFI6 TET1 siRNA Lung H1299 1.90321 0.928434 - - DataSet_03_319
IFI6 TET1 siRNA Lung A549 0.645006 -0.632615 - - DataSet_03_320
IFI6 TET1 siRNA Lung H1299 1.90321 0.928434 - - DataSet_03_321
IFI6 NFKBIZ knockout Colon Colon organoid 0.55771 -0.842413 3.619701e-01 0.748451470 DataSet_03_323
IFI6 AEBP1 siRNA Umbilical_vein HUVEC 3.69075 1.88391 8.327072e-03 0.563238092 DataSet_03_300
IFI6 EZH2 knockdown Uterus Ishikawa (ISK) cell 0.378929 -1.4 - - DataSet_03_324
IFI6 SMARCA4 siRNA Colon HCT116 0.487438 -1.03671 2.827764e-03 0.1301247 DataSet_03_302
IFI6 ELF3 knockdown Bile_duct HBDEC2 1.6237 0.699286 1.746693e-03 2.670080e-02 DataSet_03_305
IFI6 SNAI2 shRNA Pancreas KLM1 0.413016 -1.27573 3.465881e-02 0.25808333 DataSet_03_307
IFI6 EZH2 siRNA Prostate LNCaP 0.464061 -1.10761 0.0106208487 0.9997152 DataSet_03_328
IFI6 EZH2 siRNA Prostate LNCaP 0.464061 -1.10761 0.0106208487 0.9997152 DataSet_03_330
IFI6 LITAF siRNA Lymph VAL 1.56404 0.645281 6.460138e-03 0.595410476 DataSet_03_310
IFI6 EZH2 shRNA Mammary_gland MCF7 3.48171 1.7998 2.097718e-09 2.053535e-06 DataSet_03_331
IFI6 ARID3B CRISPR Colon HCT15 0.563142 -0.82843 - - DataSet_03_335
IFI6 ETV5 knockdown Colon HT29 0.0480101 -4.38052 1.095608e-05 0.009420354 DataSet_03_353
IFI6 TET1 CRISPR Mammary_gland Hs578T 2.6312 1.39572 1.477601e-02 6.283491e-02 DataSet_03_355
IFI6 PTPN14 CRISPR Brain U5-NPC 3.51593 1.81391 4.079245e-01 0.62296521 DataSet_03_357
IFI6 TP53 CRISPR Brain U5-NPC 2.76847 1.46909 1.562567e-01 2.918199e-01 DataSet_03_358
IFI6 EP300 shRNA Mammary_gland MCF10AT 4.54545 2.18443 2.919722e-03 0.036143789 DataSet_03_364
IFI6 ZNF148 shRNA Mammary_gland MDA-MB-231 1.91109 0.934395 1.778629e-02 0.097648173 DataSet_03_366
IFI6 USP22 shRNA Liver PLC_PRF_5 cells 0.5 -1 6.032404e-02 0.23644397 DataSet_03_368
IFI6 DNMT3A knockout Embryo_kidney HEK293T 3.17923 1.66868 - - DataSet_03_369
IFI6 ZFP36L1 siRNA Urinary_bladder J82 3.39721 1.76435 - - DataSet_03_371
IFI6 BHLHE40 shRNA Cervix HeLaS3 10.9487 3.45269 3.527534e-01 0.85530765 DataSet_03_372
IFI6 E2F1 siRNA Nasopharynx HK1 0.636832 -0.651016 2.532259e-02 2.194209e-01 DataSet_03_373
IFI6 HNRNPU siRNA Colon RKO 0.518582 -0.947357 - - DataSet_03_374
IFI6 SMARCA2 shRNA Lung NCI-H1944 0.608057 -0.717722 3.747705e-04 8.872096e-02 DataSet_03_377
IFI6 EZH2 CRISPR Ovary SKOV3 2.80034 1.4856 1.930160e-02 0.1114191727 DataSet_03_378
IFI6 DNMT1 siRNA Skin Human melanoma cells 5.58138 2.48062 8.708397e-08 1.064064e-05 DataSet_03_382
IFI6 YY1 shRNA Brain GSC1517 4.70507 2.23422 - - DataSet_03_384
IFI6 YY1 shRNA Brain GSC3028 0.593665 -0.75228 - - DataSet_03_386
IFI6 KAT6A CRISPR Haematopoietic_and_lymphoid_tissue MOLM-13 4.09523 2.03394 0.1820375967 0.8388073 DataSet_03_387
IFI6 TRIM8 siRNA Mammary_gland MCF7 10.6799 3.41683 3.007218e-02 0.1105689837 DataSet_03_388
IFI6 YY1 knockdown Liver HepG2 1.83898 0.878908 6.197434e-03 2.359792e-02 DataSet_03_390
IFI6 PRDM15 CRISPR Kidney Immortalized human podocytes 1.90753 0.931707 2.412430e-03 1.691295e-02 DataSet_03_391
IFI6 KDM5A CRISPR Lung GLC16 2.3439 1.22891 5.552876e-04 0.013349389 DataSet_03_392
IFI6 ILF2 siRNA Stomach SGC-7901 1.68045 0.748849 0.5690744411 0.66041517 DataSet_03_393
IFI6 ASXL1 CRISPR Embryo iPSC 0.603302 -0.729047 0.2113673751 0.8187866 DataSet_03_394
IFI6 HMGA1 shRNA Bile_duct HUCCT1 1.60943 0.686548 4.353339e-03 0.078484997 DataSet_03_400
IFI6 EHF shRNA Stomach MKN7 31.9377 4.99719 - - DataSet_03_402
IFI6 CDK7 shRNA Bone_marrow D458 2.45714 1.29698 4.216668e-02 0.29544972 DataSet_03_404
IFI6 SIRT1 siRNA Pancreas PANC1 2.46559 1.30193 1.507580e-04 0.011160383 DataSet_03_410
IFI6 USP22 shRNA Liver HuH7 0.625683 -0.676496 - - DataSet_03_411
IFI6 E2F6 shRNA Liver HuH7 0.514316 -0.959273 - - DataSet_03_412
IFI6 E2F1 siRNA Prostate LNCaP 4.47862 2.16306 3.122813e-08 0.0004331811 DataSet_03_413
IFI6 E2F2 siRNA Prostate LNCaP 4.70446 2.23403 4.074185e-09 2.871689e-05 DataSet_03_414
IFI6 ZKSCAN3 CRISPR Colon HCT116 0.169302 -2.56233 1.737031e-05 0.008204933 DataSet_03_415
IFI6 RUNX2 shRNA Cord_blood Natural Killer Cell 0.558743 -0.839744 1.154740e-01 0.793390621 DataSet_03_416
IFI6 FOXK2 shRNA Ovary OVCAR-5 0.157895 -2.66297 3.062999e-03 0.08266460 DataSet_03_419
IFI6 PRDM1 CRISPR Lymph CD8+ T cells 3.83524 1.93932 - - DataSet_03_421
IFI6 MAEL CRISPR Liver Alexander cells 0.0688576 -3.86024 - - DataSet_03_423
IFI6 STAT3 siRNA Peripheral_blood Monocyte-derived M-CSF macrophages 1.78538 0.836234 0.0551139811 1 DataSet_03_430
IFI6 USP7 shRNA Skin xenograft cells 0.291694 -1.77747 0.26760523 0.4348960 DataSet_03_431
IFI6 POU2AF1 CRISPR Haematopoietic_and_lymphoid_tissue OCI-Ly7 1.57113 0.651804 5.985455e-02 0.469075184 DataSet_03_434
IFI6 POU2AF1 CRISPR Lymph SUDHL4 13.2571 3.7287 4.654242e-04 0.009715933 DataSet_03_435
IFI6 SUFU shRNA Mammary_gland HCC1954 cells 1.75412 0.810744 0.1116311794 0.6455297 DataSet_03_437
IFI6 FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 4.76724 2.25315 5.655408e-02 0.86717312 DataSet_03_439
IFI6 FOSL1 siRNA Prostate MSKPCa3 2.23256 1.1587 0.1278297113 0.5179746 DataSet_03_445
IFI6 CAMTA1 knockout Embryo_kidney HEK293T 1.56934 0.650161 1.200753e-01 0.28932774 DataSet_03_448
IFI6 RELB CRISPR Colon SW480 2.71731 1.44218 3.373558e-04 1.267385e-02 DataSet_03_449
IFI6 CBX2 siRNA Mammary_gland MCF7 7.52071 2.91087 2.516173e-01 0.3993907913 DataSet_03_451
IFI6 SMARCA2 shRNA Lung HCC2302 0.365584 -1.45172 2.093922e-09 1.131200e-08 DataSet_03_455
IFI6 SREBF2 siRNA Umbilical_vein HUVEC 2.618 1.38847 2.469757e-01 6.906123e-01 DataSet_03_457
IFI6 ARID1A shRNA Bile_duct MMNK1 4.61793 2.20725 2.077653e-02 0.147681306 DataSet_03_458
IFI6 IRF2 shRNA Cord_Blood CD34+ cells 1.58808 0.667286 - - DataSet_03_460
IFI6 TXNIP shRNA Cord_Blood CD34+ cells 2.29983 1.20153 - - DataSet_03_461
IFI6 TXNIP shRNA Cord_blood ST3 5.19133 2.3761 4.199927e-04 0.0384557170 DataSet_03_462
IFI6 SOX9 knockout Liver HuH7 2.01351 1.00972 2.717870e-03 1.738334e-02 DataSet_03_463
IFI6 STAT3 shRNA Liver HepG2 2.10919 1.07669 2.462217e-02 0.2478282954 DataSet_03_465
IFI6 SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 2.59524 1.37587 - - DataSet_03_467
IFI6 SMARCA1 shRNA Embryo_kidney HEK293T 2.0619 1.04398 - - DataSet_03_468
IFI6 LIN28A siRNA Mammary_gland MCF7M 1.88403 0.913826 3.885141e-03 0.1721366 DataSet_03_469
IFI6 LIN28A siRNA Mammary_gland MCF7M 1.88403 0.913826 3.885141e-03 0.1721366 DataSet_03_470
IFI6 EZH2 siRNA Prostate LNCaP 0.602906 -0.729994 - - DataSet_03_472
IFI6 EZH2 siRNA Umbilical_vein HUVEC 0.587209 -0.768053 3.203407e-03 0.091896700 DataSet_03_473
IFI6 HMGB2 knockdown Umbilical_vein HUVEC 0.550388 -0.86148 1.682257e-01 0.31336867 DataSet_03_476
Regulation Region
 
T(co)Fs that significantly regulate MCM2 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of IFI6
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines